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Original Article

Radioprotection by Glutathione Esters and Cysteamine in Normal and Glutathione-depleted Mammalian Cells

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Pages 273-281 | Received 26 Jun 1987, Accepted 14 Sep 1987, Published online: 03 Jul 2009

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Angela M. Groves & Jacqueline P. Williams. (2019) Saving normal tissues – a goal for the ages. International Journal of Radiation Biology 95:7, pages 920-935.
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Joseph F. Weiss & Michael R. Landauer. (2009) History and development of radiation-protective agents. International Journal of Radiation Biology 85:7, pages 539-573.
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D. Becker, S. Summerfield, S. Gillich & M.D. Sevilla. (1994) Influence of Oxygen on the Repair of Direct Radiation Damage to DNA by Thiols in Model Systems. International Journal of Radiation Biology 65:5, pages 537-548.
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A. Prager, N.H.A. Terry & D. Murray. (1993) Influence of Intracellular Thiol and Polyamine Levels on Radioprotection by Aminothiols. International Journal of Radiation Biology 64:1, pages 71-81.
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D. Murray, A. Prager, S.C. Vanankeren, E.M. Altschuler, M.S. Kerr, N.H.A. Terry & L. Milas. (1990) Comparative Effect of the Thiols Dithiothreitol, Cysteamine and WR-151326 on Survival and on the Induction of DNA Damage in Cultured Chinese Hamster Ovary Cells Exposed to γ-radiation. International Journal of Radiation Biology 58:1, pages 71-91.
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M.F. Dennis, M.R.L. Stratford, P. Wardman & R.R. Watfa. (1989) Increase in Intracellular Cysteine after Exposure to Dithiothreitol: Implications in Radiobiology. International Journal of Radiation Biology 56:6, pages 877-883.
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Lara Cobler, Hui Zhang, Poojan Suri, Catherine Park & Luika A. Timmerman. (2018) xCT inhibition sensitizes tumors to γ-radiation via glutathione reduction. Oncotarget 9:64, pages 32280-32297.
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Anne Bravard, Monique Vacher, Eva Moritz, Laurence Vaslin, Janet Hall, Bernd Epe & J. Pablo Radicella. (2009) Oxidation Status of Human OGG1-S326C Polymorphic Variant Determines Cellular DNA Repair Capacity. Cancer Research 69:8, pages 3642-3649.
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L. Wtodek, M. Wróbel & J. Czubak. (1996) Selective effect of 2-(Polyhydroxyalkyl)-thiazolidine-4-carboxylic acids on nonprotein sulfhydryl groups in tumor bearing mice. General Pharmacology: The Vascular System 27:8, pages 1373-1376.
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B. P. Lukashin & G. A. Sofronov. (1996) Radioprotective effect of cystamine and heparin in mice with different resistance. Bulletin of Experimental Biology and Medicine 121:5, pages 492-494.
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Harjit S. Minhas & Paul J. Thornalley. (1995) Comparison of the delivery of reduced glutathione into P388D1 cells by reduced glutathione and its mono- and diethyl ester derivatives. Biochemical Pharmacology 49:10, pages 1475-1482.
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Peter E. Morris & Gordon R. Bernard. (1994) Significance of Glutathione in Lung Disease and Implications for Therapy. The American Journal of the Medical Sciences 307:2, pages 119-127.
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Jeffrey K. Rowe, Richard T. Zera, Robert D. Madoff, Andrew S. Fink, Jeanette C. Roberts, Gary R. Johnston, Daniel A. Feeney, H. L. Young & Melvin P. Bubrick. (1993) Protective effect of RibCys following high-dose irradiation of the rectosigmoid. Diseases of the Colon & Rectum 36:7, pages 681-688.
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Theodore W.C. Lo & Paul J. Thornalley. (1992) Inhibition of proliferation of human leukaemia 60 cells by diethyl esters of glyoxalase inhibitors in vitro. Biochemical Pharmacology 44:12, pages 2357-2363.
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O. Vos. (1992) Role of endogenous thiols in protection. Advances in Space Research 12:2-3, pages 201-207.
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J. C. Roberts. (1992) Amino acids and their derivatives as radioprotective agents. Amino Acids 3:1, pages 25-52.
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James B. Mitchell, William DeGraff, Dwight Kaufman, Murali C. Krishna, Amram Samuni, Eli Finkelstein, Min S. Ahn, Stephen M. Hahn, Janet Gamson & Angelo Russo. (1991) Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, Tempol. Archives of Biochemistry and Biophysics 289:1, pages 62-70.
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E. Mullaart, P.H.M. Lohman, F. Berends & J. Vijg. (1990) DNA damage metabolism and aging. Mutation Research/DNAging 237:5-6, pages 189-210.
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Peter F. Smith & Glenn F. Rush. 1990. Toxic Interactions. Toxic Interactions 87 114 .
James B. Mitchell, Angelo Russo, John A. Cook & Eli Glatstein. 1989. Drug Resistance in Cancer Therapy. Drug Resistance in Cancer Therapy 189 203 .

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