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Research Article

Effect of 6(5H)-phenanthridinone, a poly (ADP-ribose)polymerase inhibitor, and ionizing radiation on the growth of cultured lymphoma cells

Pages 685-692 | Published online: 03 Jul 2009

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Francis Dumont, Anais Altmeyer & Pierre Bischoff. (2009) Radiosensitising agents for the radiotherapy of cancer: novel molecularly targeted approaches. Expert Opinion on Therapeutic Patents 19:6, pages 775-799.
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Kathryn A. Skelding & Lisa F. Lincz. (2021) PARP Inhibitors and Haematological Malignancies—Friend or Foe?. Cancers 13:21, pages 5328.
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Rajeshwar Reddy Aleti, Alexey A. Festa, Leonid G. Voskressensky & Erik V. Van der Eycken. (2021) Synthetic Strategies in the Preparation of Phenanthridinones. Molecules 26:18, pages 5560.
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Szilvia Juhász, Rebecca Smith, Tamás SchauerDóra Spekhardt, Hasan Mamar, Siham ZentoutCatherine Chapuis, Sébastien Huet & Gyula Timinszky. (2020) The chromatin remodeler ALC1 underlies resistance to PARP inhibitor treatment. Science Advances 6:51.
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Laura Carrassa, Ilaria Colombo, Giovanna Damia & Francesco Bertoni. (2020) Targeting the DNA damage response for patients with lymphoma: Preclinical and clinical evidences. Cancer Treatment Reviews 90, pages 102090.
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Xavier Abel-Snape, Andrew Whyte & Mark Lautens. (2020) Synthesis of Aminated Phenanthridinones via Palladium/Norbornene Catalysis. Organic Letters 22:20, pages 7920-7925.
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Aaron P. Honeycutt & Jessica M. Hoover. (2018) Nickel-Catalyzed Oxidative Decarboxylative Annulation for the Synthesis of Heterocycle-Containing Phenanthridinones. Organic Letters 20:22, pages 7216-7219.
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Yi Du, Hirohito Yamaguchi, Jennifer L. Hsu & Mien-Chie Hung. (2017) PARP inhibitors as precision medicine for cancer treatment. National Science Review 4:4, pages 576-592.
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Mahesh Hegde, Kempegowda Mantelingu, Monica Pandey, Chottanahalli S. Pavankumar, Kanchugarakoppal S. Rangappa & Sathees C. Raghavan. (2016) Combinatorial Study of a Novel Poly (ADP-ribose) Polymerase Inhibitor and an HDAC Inhibitor, SAHA, in Leukemic Cell Lines. Targeted Oncology 11:5, pages 655-665.
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Atanu Ghorai, Asitikantha Sarma, Nitai P. Bhattacharyya & Utpal Ghosh. (2015) Carbon ion beam triggers both caspase-dependent and caspase-independent pathway of apoptosis in HeLa and status of PARP-1 controls intensity of apoptosis. Apoptosis 20:4, pages 562-580.
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Atanu Ghorai, Nitai P. Bhattacharyya, Asitikantha Sarma & Utpal Ghosh. (2014) Radiosensitivity and Induction of Apoptosis by High LET Carbon Ion Beam and Low LET Gamma Radiation: A Comparative Study. Scientifica 2014, pages 1-10.
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Yu Liu, Jia-Ling Zhang, Ming-Bo Zhou, Ren-Jie Song & Jin-Heng Li. (2014) Copper-catalyzed cascade cyclization of 1,7-enynes with aromatic sulfonyl chlorides toward selective assembly of benzo[j]phenanthridin-6(5H)-ones. Chem. Commun. 50:92, pages 14412-14414.
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Nicola J. Curtin & Csaba Szabo. (2013) Therapeutic applications of PARP inhibitors: Anticancer therapy and beyond. Molecular Aspects of Medicine 34:6, pages 1217-1256.
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Chun Lu, Anton V. Dubrovskiy & Richard C. Larock. (2012) Palladium-Catalyzed Annulation of Arynes by o -Halobenzamides: Synthesis of Phenanthridinones . The Journal of Organic Chemistry 77:19, pages 8648-8656.
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Yong Tang, Hossein A. Hamed, Andrew Poklepovic, Yun Dai, Steven Grant & Paul Dent. (2012) Poly(ADP-ribose) Polymerase 1 Modulates the Lethality of CHK1 Inhibitors in Mammary Tumors. Molecular Pharmacology 82:2, pages 322-332.
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C. Powell, C. Mikropoulos, S.B. Kaye, C.M. Nutting, S.A. Bhide, K. Newbold & K.J. Harrington. (2010) Pre-clinical and clinical evaluation of PARP inhibitors as tumour-specific radiosensitisers. Cancer Treatment Reviews 36:7, pages 566-575.
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Mats Ljungman. (2009) Targeting the DNA Damage Response in Cancer. Chemical Reviews 109:7, pages 2929-2950.
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Archana Dhami, Mary F. Mahon, Matthew D. Lloyd & Michael D. Threadgill. (2009) 4-Substituted 5-nitroisoquinolin-1-ones from intramolecular Pd-catalysed reaction of N-(2-alkenyl)-2-halo-3-nitrobenzamides. Tetrahedron 65:24, pages 4751-4765.
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Georges Noël, Camille Godon, Marie Fernet, Nicole Giocanti, Frédérique Mégnin-Chanet & Vincent Favaudon. (2006) Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis. Molecular Cancer Therapeutics 5:3, pages 564-574.
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William A. Brock, Luka Milas, Sherry Bergh, Ruth Lo, Csaba Szabó & Kathy A. Mason. (2004) Radiosensitization of human and rodent cell lines by INO-1001, a novel inhibitor of poly(ADP-ribose) polymerase. Cancer Letters 205:2, pages 155-160.
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B Fischer, S Benzina, V Ganansia-Leymarie, J M Denis, J P Bergerat, P Dufour, J Gueulette & P Bischoff. (2004) Cisplatin enhances the cytotoxicity of fast neutrons in a murine lymphoma cell line. Canadian Journal of Physiology and Pharmacology 82:2, pages 140-145.
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Roberto Pellicciari, Emidio Camaioni & Gabriele Costantino. 2004. 125 169 .
Lucio Tentori, Ilaria Portarena & Grazia Graziani. (2002) Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors. Pharmacological Research 45:2, pages 73-85.
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Jayshree L. Hirpara, Marie-Véronique Clément & Shazib Pervaiz. (2001) Intracellular Acidification Triggered by Mitochondrial-derived Hydrogen Peroxide Is an Effector Mechanism for Drug-induced Apoptosis in Tumor Cells. Journal of Biological Chemistry 276:1, pages 514-521.
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Donna M. Berry, Kathleen Williams & Kelly A. Meckling-Gill. (2000) All trans retinoic acid induces apoptosis in acute promyelocytic NB4 cells when combined with isoquinolinediol, a poly(ADP-ribose) polymerase inhibitor. Leukemia Research 24:4, pages 307-316.
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Serge Plaza, Marc Aumercier, Manuella Bailly, Christine Dozier & Simon Saule. (1999) Involvement of poly (ADP-Ribose)-polymerase in the Pax-6 gene regulation in neuroretina. Oncogene 18:4, pages 1041-1051.
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