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Research Article

Effect of 6(5H)-phenanthridinone, a poly (ADP-ribose)polymerase inhibitor, and ionizing radiation on the growth of cultured lymphoma cells

Pages 685-692 | Published online: 03 Jul 2009

References

  • BANASIK, M., KOMURA, H., SHIMOYAMA, M. and UEDA, K., 1992, Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl) transferase. Journal of Biochemical Chemistry, 267, 1569–1575.
  • BEN-HUR, E., CHIA-CHIEH CHEN and ELKIND, M. M., 1985, Inhibitors of poly (adenosine diphosphoribose)synthetase, examination of metabolic perturbations, and enhance-ment of radiation response in Chinese hamster cells. Cancer Research, 45, 2123 —2127.
  • BEN-HuR, E., UTSUMI, H. and ELKIND, M. M., 1984, Inhibitors of poly(ADP-ribose)synthesis, enhance radiation response by differentially affecting repair of potentially lethal versus sublethal damage. British Journal of Cancer, 49, 39–42.
  • BERGER, N. A. and BERGER, S. J., 1986, Metabolic consequences of DNA damage: the role of poly(ADP-ribose)polymerase as mediator of the suicide response. Basic Life Sciences, 38, 357–363.
  • BERGER, N. A., WEBER, G. and KAICHI, A. S., 1978, Characterization and comparison of poly(adenosine diphosphorib ose) synthesis and DNA synthesis in nucleot-ide-permeable cells. Biochimie B iophy sic Acta, 519, 87–104.
  • BILEN, J., ITTEL, M. E., NIEDERGANG, C. P., OKAZAKI, H. and MANDEL, P., 1981, Poly(adenosine diphosphate ribose)-polymerase activity in neuronal and glial nuclei in bovine c ereb rum. N eurochemical Research, 6, 1253–1263.
  • BOULTON, S., PEMBERTON, L. C., PORTEOUS, J. K., CURTIN, N. J., GRIFFIN, R. J., GoLDING, B. T. and DuRRAcz, B. W., 1995, Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose)polymerase inhibitors. British Journal of Cancer, 72, 849–856.
  • BUMP, E. A., BRAUNUT, S. J., PALAYOOR, S. T., MEDEIROS, D., LAI, L. L., CERCE, B. A., LANGLEY, R. E. and COLEMAN, C. N., 1994, Novel concepts in modification of radiation sensitivity. International Journal of Oncology, Biology, Physics, 29, 249–253.
  • BUTTKE, T. M. and SANDSTROM, P. A., 1994, Oxidative stress as a mediator of apoptosis. Immunology Today, 15, 7–10.
  • CHABERT, M., KOPP, P. C., BISCHOFF, P. L. and MANDEL, P., 1993, Cell culture of tumours alters endogeneous poly (ADPR)polymeraseexpressionandactivity.International J ournal of Cancer, 53, 837–842.
  • CHAPMAN, J. D., REUVERS, A. P., BORSA, J. and GREENSTOCK, C. L., 1973, Chemical radioprotection and radiosensitiza-tion of mammalian cells growing in vitro. Radiation Research, 56, 291–306.
  • CLEAVER, J. E. and MORGAN, W. F., 1991, Poly (ADP-rib o se)poly - merase: a perplexing participant in cellular response to DNA breakage. Mutation Research, 257, 1–18.
  • COLE, L. J. and ELLIS, M. E., 1957, Radiation-induced changes in tissue nucleic acids: Release of soluble deoxypolynucle- 0IideS in the spleen. Radiation Research, 7, 508–516.
  • DARMON, A. J., NICHOLSON, D. W. and BLEACKLEY, R. C., 1995, Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature, 377, 446–448.
  • DARROUDI, F., ZWANNENBERG, T. S. B., NATARAJAN, A. T., DR1ESSEN, 0. and VAN LANGEVELDE, A., 1989, Reduced tumor progression in vivo by inhibitor of poly(ADP-ribose) synthetase (3-aminobenzamide) in combination with X-rays or the cytostatic drug DTIC. In: ADP-ribose Transfer Reactions Mechanisms and Biological Significance, edited by M. K. Jacobson and E. L. Jacobson (New York: Springer Verlag), pp. 390–395.
  • DEMURCIA, J. M., NIEDERGANG, C., TRUCCO, C., RICOUL, M., DUTRILLAUX, B., MARK, M. et al., 1997, Requirement of poly(ADP-ribose)polymerase in recovery from DNA damage in mice and in cells. Proceedings of the National Academy of Sciences USA, 94(14), 7303–7307.
  • DESCHAVANNE, P. J. and FERTIL, B., 1996, A review of human Cell radiosensitivity in vitro. International J ournal of Radiation Oncology, Biology, Physics, 34, 251–266.
  • DEWEY, W. C., LING, C. C. and MEYN, R. E., 1995, Radiation-induced apoptosis: relevance to radiotherapy. International Journal of Radiation Oncology, Biology, Physics, 33, 781 —796.
  • DEWIT, L., 1987, Combined treatment of radiation and cisplati-num: a review of experimental and clinical data. International Journal of Radiation Oncology, Biology, Physics, 13, 403–416.
  • GIOCANTI, N., HENNEQUIN, C., BALOSSO, J., MAHLER, M. and FAVAUDON, V., 1993, DNA repair and cell cycle inter-actions in radiation sensitization by the topoisomerase II pOISOn etoposide. Cancer Research, 53, 2105–2111.
  • GRIFFIN, R. J., CURTIN, N. J., NEWELL, D. R., GOLDING, B. T., DURKACZ, B. W. and CALvERT, A. H., 1995, The role of inhibitors of poly(ADP-ribose)polymerase as resistance-modifying agents in cancer therapy. Biochimie, 77, 408–422.
  • HAIMOVITZ-FRIEDMAN, A., KAN, C. C., EHLEITER, D., PERSAUD, R. S., MCLOUGHLIN, M., FUKS, Z. and KOLESNICK, R. N., 1994, Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. Journal of Experimental Medicine, 180, 525–535.
  • HICICVIAN, J. A., 1992, Apoptosis induced by anticancer drugs. Cancer and Metastasis Reviews, 11, 121–139.
  • HIETTER, H., BISCHOFF, P., BECK, J. P., OURISSON, G. and Luu, B., 1986, Comparative effects of 7fi-hydroxycholes-terol towards murine lymphoma, lymphoblasts and lymphocytes: selective cytotoxicity and blastogenesis inhibition. Cancer Biochemistry & Biophysics, 9, 75–83.
  • HORSMAN, M. R., HOVER, M., HONESS, D., DENNIS, I. F. and OVERGAAR DD., 1993, Nicotinamide pharmacokinetics in humans and mice: a comparative assessment and the implications for radiotherapy. Radiotherapy and Oncology, 27, 131–139.
  • HUET, J. and LAVAL, F., 1985, Influence of poly(ADP-ribose)-sinthesis inhibitors on the repair of sublethal and poten-tially lethal damage in y-irradiated mammalian cells. International Journal of Radiation Biology, 47, 655–662.
  • KELLAND, L. R. and TomuN, K. S., 1989, The effect of 3-aminobenzamide in the radiation response of the human cervix carcinoma xenografts. Radiotherapy and Oncology, 15, 363–369.
  • LANGLEY, R. E., PALAYOOR, S. T., COLEMAN, C. N. and BUMP, E. A., 1993, Modifiers of radiation-induced apoptosis. Radiation Research, 136, 320–326.
  • LAUTIER, D., LAGUEUX, J., THIBODEAU, J., MENARD, L. and POIRIER, G. G., 1993, Molecular and biochemical features of poly(ADP-ribose) metabolism. Molecular and Cellular Biochemistry, 122, 171–193.
  • MAJNO, G. and JORIS, I., 1995, Apoptosis, oncosis and necrosis: an overview of cell death. American Journal of Pathology, 146, 3–15.
  • MARTIN, L. M., THOMAS, C. D. and GUICHARD, M., 1994, Nicotinamide and carbogen: relationship between p02 and radiosensitivity in three tumour lines. International Journal of Radiation Biology, 65, 379–386.
  • MASUTANI, M., NOZAKI, T., WAKABAYASHI, K. and SUGIMURA, T., 1995, Role of poly(ADP-ribose)polymerase in cell-cycle checkpoint mechanisms following y-irradi-ation. Biochimie, 77, 462–465.
  • MCCLAIN, D. E., KALINICH, J. F. and RAMAKRISHNAN, N.7 1995, Trolox inhibits apoptosis in irradiated MOLT-4 lympho-cytes. FASE B Journal, 9, 1345–1354.
  • MEYN, R. E., STEPHENS, L. C. and MILAS, L., 1995, Programmed cell death and radioresistance. cancer Metastasis Review, 15, 119–131.
  • MILAM, K. M. and CLEAVER, J. E., 1984, Inhibitors of poly(ad-enosine diphophate ribose)synthesis: effect on other meta-bolic processes. Science, 223, 589–591.
  • MIRKovic, N., MEYN, R. E., HUNTER, N. R. and MITAs, L., 1994, Radiation-induced apoptosis in a murine lymphoma in vivo. Radiotherapy and Oncology, 33, 11–16.
  • MITCHELL, J. B. and GLATSTEIN, E.7 1991, Radiation oncology: past achievements and ongoing controversies. Cancer Research, 51, (suppl), 5065S–5073S.
  • NELIPOVICH, P. A., NIKONOVA, L. V. and UMANSKY, S. R.7 1988, Inhibition of poly(ADP-ribose)polymerase as a possible reason for activation of Ca2±/ Me-dependent endonu-clease in thymocytes of irradiated rats. International Journal of Radiation Biology & Related Studies in Physics, Chemistry & Medicine, 53(5), 749–765.
  • NICOLETTI, I., MIGLIORATI, G., PAGLIACCI, M. C., GRIGNANI, F. and RICARDI, C., 1991, A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. Journal of Immunological Methods, 139, 271–276.
  • PAGE, B., PAGE, M. and NOEL, C.7 1993, A new fluorometric assay for cytotoxicity measurements in vitro. International Journal of Oncology, 3, 473–476.
  • PHILLIPS, R. A. and TOLMACH, L. J., 1966, Repair of potentially lethal damage in X-irradiated HeLa cells. Radiation Research, 29, 413–432.
  • ROCKWELL, S., 1983, Effects of mitomycin C alone and in combination with X-rays on EMT6 mouse mammary tumors in vivo. Journal of National Cancer Institute, 71, 768–771.
  • SATOH, M. S. and LINDAHL, T.7 1992, Role of poly(ADP-ribose) formation in DNA repair. Nature, 356, 356–358.
  • SCHLEGEL, J., PETERS, I., ORRENIUS, S., MILLER, D. K., THORNBERRY, N. A., YAmiN, T. T. and NicHoTsoN, D. W., 1996, CPP32 apopain is a key interleukin 1 beta converting enzyme-like protease involved in Fas-mediated apoptosis. Journal of Biological Chemistry, 271, 1841–1844.
  • SCHREK, R., 1955, Cinemicrographic observations and theoret-ical considerations on reactions of lymphocytes to X-rays. Radiology, 65, 912–919.
  • SEBOLT-LEOPOLD, J. S. and SCAVONE, S. V.71992, Enhancement of alkylating agent activity in vitro by PD128763, a potent poly(ADP-ribose)synthetaSe inhibitor. International Journal of Radiation Oncology, Biology, Physics, 22, 619–621.
  • SOLDATENKOV, V. A., PRASAD, S., NOTARIO, V. and DRITSCHILO, A., 1995, Radiation-induced apoptosis of Ewing's sarcoma cells: DNA fragmentation and proteo-lysis of poly(ADP-ribose)polymerase. Cancer Research, 55, 4240–4242.
  • THRAVES, P., MOSSMAN, K. L., BRENNAN, T. and DRITSCHILO, A.7 1986, Differential radiosensitization of human tumor cells by 3-aminobenzamide and benzamide: inhibitors of poly(ADP-ribosylation). International Journal of Radiation Biology, 50, 961–972.
  • UMANSKY, S. R., 1991, Apoptotic process in the radiation-induced death of lymphocytes. In: Apoptosis: The Molecular Basis of Cell D eath, edited by L. D. Tomei and F. 0. Cope (Cold Spring Harbor: Lab. Press), pp. 193–208.
  • VAN GOOL, L., MEYER, R., TOBIASCH, E., CZIEPLUCH, C., JAUNIAUX, J. C., MINCHEVA, A. et al., 1997, Overexpression of human poly(ADP-ribose)polymerase in transfected hamster cells leads to increased poly(ADP-ribosyl)ation and cellular sensitization to gamma irradi-ation. European Journal of Biochemistry, 244(1), 15–20.
  • WAMBERSIE, A. and WHITMORE, G. F.7 1995, Radiation therapy. ICRU News, X-ray Centenary Issue, 15–20.
  • WEIBERG, M. J. and RAUTH, A. M.71987, 5-flu orou racil infusions and fractionated doses of radiation: studies with a murine carcinoma. InternationalJ ournal of Radiation Oncology, Biology, Physics, 33, 1691–1699.
  • WELTIN, D., MARCHAL, J., DUFOUR, P., POTWOROWSKI, E., 0TH, D. and BISCHOFF, P., 1994, Effect of 6(5H)-phen-anthridinone, an inhibitor of poly(ADP-ribose)poly-merase, on cultured tumor cells. Oncology Research, 6, 399–403.
  • WELTIN, D., PICARD, V., AUPEIX, K., VARIN, M., 0TH, D., MARCHAL, J., DUFOUR, P. and BISCHOFF, P.7 1995, Immunosuppressive activities of 6(5H)-phenanthridinone, a new poly(ADP-ribose)polymerase inhibitor. International Journal of Immunopharmacology, 17, 265–271.

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