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Critical Reviews in Food Science and Nutrition Volume 60, 2020 - Issue 21
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Occurrence, biological properties and potential effects on human health of β-casomorphin 7: Current knowledge and concerns

Andrea SummerDepartment of Veterinary Sciences, Università di Parma, Parma, Italy; View further author information
,
Federica Di FrangiaDepartment of Veterinary Sciences, Università di Parma, Parma, Italy; View further author information
,
Paolo Ajmone MarsanDepartment of Animal Science, Food and Nutrition (DIANA) and Nutrigenomics and Proteomics Research Center (PRONUTRIGEN), Università Cattolica del Sacro Cuore, Piacenza, Italy; ORCID Iconhttp://orcid.org/0000-0003-3165-4579View further author information
ORCID Icon,
Ivano De NoniDepartment of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, Milan, ItalyCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-1281-7053View further author information
ORCID Icon &
Massimo MalacarneDepartment of Veterinary Sciences, Università di Parma, Parma, Italy; ORCID Iconhttp://orcid.org/0000-0003-3329-698XView further author information
ORCID Icon
Pages 3705-3723 | Published online: 07 Feb 2020

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Melanie Salmasi, Riccardo Moretti, Stefania Chessa, Stefano Sartore, Antonio Mimosi & Paolo Cornale. (2020) Genetic variability of milk proteins in two cattle breeds of Piedmont region and the potential effects on milk quality. Italian Journal of Animal Science 19:1, pages 1483-1489.
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Stefania Chessa, Stefano Gattolin, Paola Cremonesi, Dominga Soglia, Raffaella Finocchiaro, Jan-Thijs Van Kaam, Maurizio Marusi & Giorgio Civati. (2020) The effect of selection on casein genetic polymorphisms and haplotypes in Italian Holstein cattle. Italian Journal of Animal Science 19:1, pages 833-839.
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Articles from other publishers (25)

Huijin Jeong, Young-Seo Park & Sung-Sik Yoon. (2023) A2 milk consumption and its health benefits: an update. Food Science and Biotechnology.
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Massimo Malacarne, Piero Franceschi, Stefania Chessa & Andrea Summer. (2023) Editorial: Genetic factors affecting the nutritional and processing quality of milk. Frontiers in Animal Science 4.
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Marta Liliane de Vasconcelos, Luisa Maria F. S. Oliveira, Jeremy Paul Hill & Ana Maria Centola Vidal. (2023) Difficulties in Establishing the Adverse Effects of β-Casomorphin-7 Released from β-Casein Variants—A Review. Foods 12:17, pages 3151.
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C. Bengtsson, H. Stålhammar, J.R. Thomasen, W.F. Fikse, E. Strandberg & S. Eriksson. (2023) Mating allocations in Holstein combining genomic information and linear programming optimization at the herd level. Journal of Dairy Science 106:5, pages 3359-3375.
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Roman Kulibaba, Mykola Sakhatskyi & Yuriy Liashenko. (2023) Analysis of genotyping features of bovine cattle individuals at the CSN2 locus using ACRS-PCR methods. Animal Science and Food Technology 14:2.
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Stefano Cattaneo, Fabio Masotti, Milda Stuknytė & Ivano De Noni. (2023) Impact of in vitro static digestion method on the release of β-casomorphin-7 from bovine milk and cheeses with A1 or A2 β-casein phenotypes. Food Chemistry 404, pages 134617.
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Martina Miluchová, Michal Gábor & Juraj Candrák. (2023) The Effect of the Genotypes of the CSN2 Gene on Test-Day Milk Yields in the Slovak Holstein Cow. Agriculture 13:1, pages 154.
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Anna Cieślińska, Ewa Fiedorowicz, Dominika Rozmus, Edyta Sienkiewicz-Szłapka, Beata Jarmołowska & Stanisław Kamiński. (2022) Does a Little Difference Make a Big Difference? Bovine β-Casein A1 and A2 Variants and Human Health—An Update. International Journal of Molecular Sciences 23:24, pages 15637.
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Bibiana Juan & Antonio-José Trujillo. (2022) Acid and Rennet Coagulation Properties of A2 Milk. Foods 11:22, pages 3648.
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V. Vigolo, M. Franzoi, F. Cendron, G. Salvadore, M. Penasa, M. Cassandro & M. De Marchi. (2022) Characterization of the genetic polymorphism linked to the β-casein A1/A2 alleles using different molecular and biochemical methods. Journal of Dairy Science 105:11, pages 8946-8955.
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Barana Hewa Nadugala, Charles N. Pagel, Jared K. Raynes, C.S. Ranadheera & Amy Logan. (2022) The effect of casein genetic variants, glycosylation and phosphorylation on bovine milk protein structure, technological properties, nutrition and product manufacture. International Dairy Journal 133, pages 105440.
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Henrietta Buzás, Rita Székelyhidi, Gabor Szafner, Katalin Szabó, Judit Süle, Solveig Bukovics & Attila József Kovács. (2022) Developed rapid and simple RP-HPLC method for simultaneous separation and quantification of bovine milk protein fractions and their genetic variants. Analytical Biochemistry, pages 114939.
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Salvador Fernández-Rico, Alicia del Carmen Mondragón, Aroa López-Santamarina, Alejandra Cardelle-Cobas, Patricia Regal, Alexandre Lamas, Israel Samuel Ibarra, Alberto Cepeda & José Manuel Miranda. (2022) A2 Milk: New Perspectives for Food Technology and Human Health. Foods 11:16, pages 2387.
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Manishi Mukesh, Shelesh Swami, Gaurav Bhakhri, Vipul Chaudhary, Vishal Sharma, Nikita Goyal, Prince Vivek, Vijaya Dalal, A. K. Mohanty, R. S. Kataria, Parvesh Kumari, Saket K. Niranjan & Monika Sodhi. (2022) Demographic pattern of A1/A2 beta casein variants indicates conservation of A2 type haplotype across native cattle breeds (Bos indicus) of India. 3 Biotech 12:8.
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Nicolò Amalfitano, Lucio Flavio Macedo Mota, GuilhermeJ.M. Rosa, Alessio Cecchinato & Giovanni Bittante. (2022) Role of CSN2, CSN3, and BLG genes and the polygenic background in the cattle milk protein profile. Journal of Dairy Science 105:7, pages 6001-6020.
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V. Bisutti, S. Pegolo, D. Giannuzzi, L.F.M. Mota, A. Vanzin, A. Toscano, E. Trevisi, P. Ajmone Marsan, M. Brasca & A. Cecchinato. (2022) The β-casein (CSN2) A2 allelic variant alters milk protein profile and slightly worsens coagulation properties in Holstein cows. Journal of Dairy Science 105:5, pages 3794-3809.
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Alexandre N. Oglobline, Matthew P. Padula & Philip A. Doble. (2022) Quality control of A1-free dairy. Food Control 135, pages 108685.
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Marzia Giribaldi, Cristina Lamberti, Simona Cirrincione, Maria Gabriella Giuffrida & Laura Cavallarin. (2022) A2 Milk and BCM-7 Peptide as Emerging Parameters of Milk Quality. Frontiers in Nutrition 9.
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Arti Prasad & Naresh Kothari. (2021) Cow products: boon to human health and food security. Tropical Animal Health and Production 54:1.
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Stefan Ehling, Meibo Wang & Luke Weber. (2021) Determination of Total and A1-Type β-Casein in Milk and Milk-Derived Ingredients by Liquid Chromatography-Mass Spectrometry Using Characteristic Tryptic Peptides. Journal of AOAC INTERNATIONAL 104:6, pages 1559-1566.
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Vito Leonardo Miniello, Maria Carmen Verga, Andrea Miniello, Cristina Di Mauro, Lucia Diaferio & Ruggiero Francavilla. (2021) Complementary Feeding and Iron Status: “The Unbearable Lightness of Being” Infants. Nutrients 13:12, pages 4201.
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Valentina Pica, Milda Stuknytė, Fabio Masotti, Ivano De Noni & Stefano Cattaneo. (2021) Model infant biscuits release the opioid-acting peptides milk β-casomorphins and gluten exorphins after in vitro gastrointestinal digestion. Food Chemistry 362, pages 130262.
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Aigerim Zh. Khastayeva, Laura A. Mamayeva, Aizhan T. Abylgazinova, Venera S. Zhamurova, Nurlybek Zh. Karimov & Karlygash M. Muratbekova. (2021) RETRACTED ARTICLE: Influence of the kappa casein genotype on the technological properties of cow milk of Simmental and Alatau breeds. Functional & Integrative Genomics 21:2, pages 231-238.
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Valentina Pica, Milda Stuknytė, Fabio Masotti, Ivano De Noni & Stefano Cattaneo. (2021) Bovine milk fortifiers and fortified pasteurized donor human milk for premature infant nutrition. Peptidomic overview. LWT 135, pages 110037.
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Norberto A. Guzman & Daniel E. Guzman. (2020) A Two-Dimensional Affinity Capture and Separation Mini-Platform for the Isolation, Enrichment, and Quantification of Biomarkers and Its Potential Use for Liquid Biopsy. Biomedicines 8:8, pages 255.
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