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Research Article

Mode of Action: Neurotoxicity Induced by Thyroid Hormone Disruption During Development—Hearing Loss Resulting From Exposure to PHAHs

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Pages 757-769 | Published online: 10 Oct 2008

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Stephanie Melching-Kollmuss, Kathrin Bothe, Alex Charlton, Babunilayam Gangadharan, Rashin Ghaffari, Sylvia Jacobi, Sue Marty, Heike-Antje Marxfeld, Elizabeth F. McInnes, Ursula G. Sauer, Larry P. Sheets, Christian Strupp, Helen Tinwell, Christiane Wiemann, Philip A. Botham & Bennard van Ravenzwaay. (2023) Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – Part IV: the ECETOC and CLE Proposal for a Thyroid Function-Related Neurodevelopmental Toxicity Testing and Assessment Scheme (Thyroid-NDT-TAS). Critical Reviews in Toxicology 53:6, pages 339-371.
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Sue Marty, Manon Beekhuijzen, Alex Charlton, Nina Hallmark, Bethany R. Hannas, Sylvia Jacobi, Stephanie Melching-Kollmuss, Ursula G. Sauer, Larry P. Sheets, Volker Strauss, Daniel Urbisch, Philip A. Botham & Bennard van Ravenzwaay. (2021) Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part II: how can key events of relevant adverse outcome pathways be addressed in toxicological assessments?. Critical Reviews in Toxicology 51:4, pages 328-358.
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Anna Bal-Price, Kevin M. Crofton, Magdalini Sachana, Timothy J. Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J. Lein, Jochem Louisse, Florianne Monnet-Tschudi, Alicia Paini, Alexandra Rolaki, André Schrattenholz, Cristina Suñol, Christoph van Thriel, Maurice Whelan & Ellen Fritsche. (2015) Putative adverse outcome pathways relevant to neurotoxicity. Critical Reviews in Toxicology 45:1, pages 83-91.
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Ulf Hammerling, Annika Tallsjö, Roland Grafström & Nils-Gunnar Ilbäck. (2009) Comparative Hazard Characterization in Food Toxicology. Critical Reviews in Food Science and Nutrition 49:7, pages 626-669.
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KathrynZ. Guyton, Stanley Barone$suffix/text()$suffix/text(), RebeccaC. Brown, SusanY. Euling, Jennifer Jinot & Susan Makris. (2008) Mode of Action Frameworks: A Critical Analysis. Journal of Toxicology and Environmental Health, Part B 11:1, pages 16-31.
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Alan R. Boobis, John E. Doe, Barbara Heinrich-Hirsch, M. E. (Bette) Meek, Sharon Munn, Mathuros Ruchirawat, Josef Schlatter, Jennifer Seed & Carolyn Vickers. (2008) IPCS Framework for Analyzing the Relevance of a Noncancer Mode of Action for Humans. Critical Reviews in Toxicology 38:2, pages 87-96.
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