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Original Article

Myeloma of the Central Nervous System: Strong Association with Unfavorable Chromosomal Abnormalities and Other High-risk Disease Features

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Pages 291-300 | Received 23 Jun 2003, Published online: 03 Aug 2009

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Nazanin Majd, Xiao Wei, Alexis Demopoulos, Adilia Hormigo & Ajai Chari. (2016) Characterization of central nervous system multiple myeloma in the era of novel therapies. Leukemia & Lymphoma 57:7, pages 1709-1713.
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P Vermeiren, A Vantilborgh & F Offner. (2011) MYELOMA OF THE CENTRAL NERVOUS SYSTEM: REPORT OF A SINGLE CENTER CASE SERIES. Acta Clinica Belgica 66:3, pages 205-208.
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Mark Podberezin. (2017) Case Study of Intracerebral Recurrence of Plasmablastic Myeloma with Achievement of Complete Response after Treatment with Lenalidomide. Advances in Cytology & Pathology 2:3.
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S. Jennane, M. Kerbout, E.M. Mahtat, J. Konopacki & J.V. Malfuson. (2016) Plasmocytomes intraduraux extram?dullaires. Pratique Neurologique - FMC 7:3, pages 209-212.
Crossref
Nischala Ammannagari, Kimberly Celotto, Vishala Neppalli, Kelvin Lee & Sarah A. Holstein. (2016) Anaplastic Multiple Myeloma: An Aggressive Variant With a Poor Response to Novel Therapies. Clinical Lymphoma Myeloma and Leukemia 16:9, pages e129-e131.
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Artur Jurczyszyn, Norbert Grzasko, Alessandro Gozzetti, Jacek Czepiel, Alfonso Cerase, Vania Hungria, Edvan Crusoe, Ana Luiza Miranda Silva Dias, Ravi Vij, Mark A. Fiala, Jo Caers, Leo Rasche, Ajay K. Nooka, Sagar Lonial, David H. Vesole, Sandhya Philip, Shane Gangatharan, Agnieszka Druzd-Sitek, Jan Walewski, Alessandro Corso, Federica Cocito, Marie-Christine M. Vekemans, Erden Atilla, Meral Beksac, Xavier Leleu, Julio Davila, Ashraf Badros, Ekta Aneja, Niels Abildgaard, Efstathios Kastritis, Dorotea Fantl, Natalia Schutz, Tomas Pika, Aleksandra Butrym, Magdalena Olszewska-Szopa, Lidia Usnarska-Zubkiewicz, Saad Z. Usmani, Hareth Nahi, Chor S Chim, Chaim Shustik, Krzysztof Madry, Suzanne Lentzsch, Alina Swiderska, Grzegorz Helbig, Renata Guzicka-Kazimierczak, Nikoletta Lendvai, Anders Waage, Kristian T. Andersen, Hirokazu Murakami, Sonja Zweegman & Jorge J. Castillo. (2016) Central nervous system involvement by multiple myeloma: A multi-institutional retrospective study of 172 patients in daily clinical practice. American Journal of Hematology 91:6, pages 575-580.
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Melissa Gaik-Ming Ooi, Sanjay de Mel & Wee Joo Chng. (2016) Risk Stratification in Multiple Myeloma. Current Hematologic Malignancy Reports 11:2, pages 137-147.
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Jiajia Zhang & Yuping Zhong. (2015) Clinical analysis of 36 multiple myeloma patients with extramedullary plasmacytoma invasion of the spinal canal. Hematological Oncology 33:2, pages 75-79.
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Artur Jurczyszyn, Magdalena Olszewska-Szopa, Szymon Fornagiel & Aleksander Skotnicki. (2015) Zajęcie ośrodkowego układu nerwowego w przebiegu szpiczaka plazmocytowego – opis przypadku i przegląd literatury. Acta Haematologica Polonica 46:3, pages 242-247.
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Katya A. Shpilberg, Steven J. Esses, Mary E. Fowkes, Ajai Chari, Michael Sacher & Thomas P. Naidich. (2015) Imaging of extraosseous intracranial and intraspinal multiple myeloma, including central nervous system involvement. Clinical Imaging 39:2, pages 213-219.
Crossref
Hirono Iriuchishima, Takayuki Saitoh, Hiroshi Handa, Atsushi Isoda, Morio Matsumoto, Morio Sawamura, Atsushi Iwasaki, Chiaki Ushie, Hikaru Hattori, Yoshiko Sasaki, Takeki Mitsui, Akihiko Yokohama, Norifumi Tsukamoto, Hirokazu Murakami & Yoshihisa Nojima. (2015) A new staging system to predict prognosis of patients with multiple myeloma in an era of novel therapeutic agents. European Journal of Haematology 94:2, pages 145-151.
Crossref
Xiaoyan Qu, Lijuan Chen, Hairong Qiu, Hua Lu, Hanxin Wu, Hongxia Qiu, Peng Liu, Rui Guo & Jianyong Li. (2015) Extramedullary Manifestation in Multiple Myeloma Bears High Incidence of Poor Cytogenetic Aberration and Novel Agents Resistance. BioMed Research International 2015, pages 1-7.
Crossref
Chafic Y. Karam & Michelle L. Mauermann. 2014. Multiple Myeloma. Multiple Myeloma 245 255 .
Joan Bladé & Laura Rosiñol. 2013. Neoplastic Diseases of the Blood. Neoplastic Diseases of the Blood 665 680 .
Shane A Gangatharan, Dennis A Carney, H Miles Prince, Max M Wolf, E Henry Januszewicz, David S Ritchie & Simon J Harrison. (2011) Emergence of central nervous system myeloma in the era of novel agents. Hematological Oncology 30:4, pages 170-174.
Crossref
Hanny Haaxma-Reiche. 2012. Neuro-Oncology Part II. Neuro-Oncology Part II 711 729 .
Jan Drappatz & Kurt A. Jaeckle. 2012. Lymphoma and Leukemia of the Nervous System. Lymphoma and Leukemia of the Nervous System 299 312 .
Joan BladéCarlos Fernández de LarreaLaura RosiñolMaría Teresa CibeiraRaquel JiménezRay Powles. (2011) Soft-Tissue Plasmacytomas in Multiple Myeloma: Incidence, Mechanisms of Extramedullary Spread, and Treatment Approach. Journal of Clinical Oncology 29:28, pages 3805-3812.
Crossref
Ba D. Nguyen, Panol C. Ram & Michael C. Roarke. (2010) PET/CT and MR Imaging of Central Nervous System Myelomatosis. Clinical Nuclear Medicine 35:12, pages 953-955.
Crossref
C. S. Chim, A. K. W. Lie, E. Y. T. Chan, Y. Y. Leung, S. C. W. Cheung, S. Y. T. Chan, Raymond Liang & Y. L. Kwong. (2010) A staged approach with vincristine, adriamycin, and dexamethasone followed by bortezomib, thalidomide, and dexamethasone before autologous hematopoietic stem cell transplantation in the treatment of newly diagnosed multiple myeloma. Annals of Hematology 89:10, pages 1019-1027.
Crossref
R. Velasco, J. Petit, R. Llatjós, A. Juan & J. Bruna. (2010) Can leptomeningeal myelomatosis be predicted in patients with IgD multiple myeloma?. Journal of Clinical Neuroscience 17:8, pages 1071-1072.
Crossref
Abdul Rahman Mourad, Mohamed A. Kharfan-Dabaja, Kaaron Benson, Lynn C. Moscinski & Rachid C. Baz. (2010) Leptomeningeal Myeloma As the Sole Manifestation of Relapse: An Unusual Presentation. The American Journal of the Medical Sciences 339:1, pages 81-82.
Crossref
Julie M. Wu, Matthew F. Georgy, Frances H. Burroughs, Edward G. Weir, Dorothy L. Rosenthal & Syed Z. Ali. (2009) Lymphoma, leukemia, and pleiocytosis in cerebrospinal fluid: Is accurate cytopathologic diagnosis possible based on morphology alone?. Diagnostic Cytopathology 37:11, pages 820-824.
Crossref
Joan Bladé & Laura Rosiñol. 2009. Treatment of Multiple Myeloma and Related Disorders. Treatment of Multiple Myeloma and Related Disorders 76 85 .
M C Minnema, N W C J van de Donk, S Zweegman, U Hegenbart, S Schonland, R Raymakers, J M J M Zijlmans, M J Kersten, G M J Bos & H M Lokhorst. (2008) Extramedullary relapses after allogeneic non-myeloablative stem cell transplantation in multiple myeloma patients do not negatively affect treatment outcome. Bone Marrow Transplantation 41:9, pages 779-784.
Crossref
Joan Blad?Laura Rosi?ol. (2007) Complications of Multiple Myeloma. Hematology/Oncology Clinics of North America 21:6, pages 1231-1246.
Crossref
Marianna Colagrande, Mauro Di Ianni, Raffaella Ciurnelli, Massimo Gallucci, Guglielmo Mariani & Antonio Tabilio. (2007) Striking response to intrathecal liposomal cytarabine in a patient with meningeal myelomatosis. British Journal of Haematology 138:6, pages 812-813.
Crossref
Aurelia Wavre, Audrey S. Baur, Michael Betz, Dominique Mühlematter, Martine Jotterand, Khalil Zaman & Nicolas Ketterer. (2007) Case study of intracerebral plasmacytoma as an initial presentation of multiple myeloma. Neuro-Oncology 9:3, pages 370-372.
Crossref
Andrea Wong, Noorainun Md Yusof, Sing-Huang Tan & Wee J Chng. (2005) Multiple Myeloma Presenting with Complex Cranial Nerve Palsies. Journal of Neuro-Oncology 74:2, pages 217-218.
Crossref

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