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Lu Ding, Wan Zhang, Lili Yang, Helene Pelicano, Kaiwen Zhou, Ran Yin, Ruibin Huang & Junyi Zeng. (2018) Targeting the autophagy in bone marrow stromal cells overcomes resistance to vorinostat in chronic lymphocytic leukemia. OncoTargets and Therapy 11, pages 5151-5170.
Read now
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Kyle Crassini, Yandong Shen, Stephen Mulligan & O. Giles Best. (2017) Modeling the chronic lymphocytic leukemia microenvironment in vitro. Leukemia & Lymphoma 58:2, pages 266-279.
Read now
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Sanne H. Tonino, Chantal E. Mulkens, Jacoline van Laar, Ingrid A. M. Derks, Guangli Suo, Fransien Croon-de Boer, Marinus H. J. van Oers, Eric Eldering, Jean Y. Wang & Arnon P. Kater. (2015) Induction of TAp73 by platinum-based compounds to overcome drug resistance in p53 dysfunctional chronic lymphocytic leukemia. Leukemia & Lymphoma 56:8, pages 2439-2447.
Read now
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Ronald J. Hill, Yan Lou & Seng-Lai Tan. (2013) B-Cell Antigen Receptor Signaling in Chronic Lymphocytic Leukemia: Therapeutic Targets and Translational Opportunities. International Reviews of Immunology 32:4, pages 377-396.
Read now
Read now
Melinda Burgess, Catherine Cheung, Lynne Chambers, Karunya Ravindranath, Gunjeet Minhas, Louise Knop, Peter Mollee, Nigel A. J. McMillan & Devinder Gill. (2012) CCL2 and CXCL2 enhance survival of primary chronic lymphocytic leukemia cells in vitro. Leukemia & Lymphoma 53:10, pages 1988-1998.
Read now
Read now
Rachel E. Hayden, Guy Pratt, Claudia Roberts, Mark T. Drayson & Chris M. Bunce. (2012) Treatment of chronic lymphocytic leukemia requires targeting of the protective lymph node environment with novel therapeutic approaches. Leukemia & Lymphoma 53:4, pages 537-549.
Read now
Read now
PaulaX. Fernández-Calotti, Dolors Colomer & Marçal Pastor-Anglada. (2011) Translocation of Nucleoside Analogs Across the Plasma Membrane in Hematologic Malignancies. Nucleosides, Nucleotides & Nucleic Acids 30:12, pages 1324-1340.
Read now
Read now
Eva M. Trinidad, Agustín G. Zapata & Luis M. Alonso-Colmenar. (2010) Eph-ephrin bidirectional signaling comes into the context of lymphocyte transendothelial migration. Cell Adhesion & Migration 4:3, pages 363-367.
Read now
Read now
Zhifeng Yu, Baohua Sun, Hagop M. Kantarjian, Michael J. Keating, Hesham M. Amin & Xiaoping Sun. (2008) Protein expression profiling of cytokines and cytokine receptors on purified chronic lymphocytic leukemia cells from patients with favourable prognostic indicators. Leukemia & Lymphoma 49:4, pages 751-756.
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Articles from other publishers (95)
Atefeh Khodakarami, Mahsa Afsari Kashani, Atefeh Nazer, Armin Mahmoudsalehi Kheshti, Bentolhoda Rashidi, Vahid Karpisheh, Ali Masjedi, Shiva Abolhasani, Sepideh Izadi, Rafieh Bagherifar, Seyyed Sina Hejazian, Hamed Mohammadi, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Mohammad Hojjat-Farsangi & Farhad Jadidi-Niaragh. (2023) Targeted Silencing of NRF2 by rituximab-conjugated nanoparticles increases the sensitivity of chronic lymphoblastic leukemia cells to Cyclophosphamide. Cell Communication and Signaling 21:1.
Crossref
Crossref
Anne Kruchen, Pascal-David Johann, Laura Rekowski & Ingo Müller. (2023) Epigenetic Modification of Mesenchymal Stromal Cells Derived from Bone Marrow and Embryonal Tumors to Facilitate Immunotherapeutic Approaches in Pediatric Malignancies. Current Issues in Molecular Biology 45:3, pages 2121-2135.
Crossref
Crossref
Zekhethelo A. Mkhwanazi, Tawanda M. Nyambuya, Snenhlanhla A. Mfusi & Bongani B. Nkambule. (2022) Prognostic markers in patients with chronic lymphocytic leukaemia on targeted therapy, chemoimmunotherapy with anti-CD20 monoclonal antibody: a systematic review and meta-analysis of prognostic factors. BMC Cancer 22:1.
Crossref
Crossref
Weihang Shan, Guixiang Wu, Yueting Huang, Hanyan Zeng, Weilin Xia, Zhijuan Lin & Bing Xu. (2022) Adverse events in lymphoma patients treated with phosphoinositide 3 kinase Inhibitor in clinical trials: a meta-analysis. Annals of Hematology 101:8, pages 1741-1753.
Crossref
Crossref
Helena Olbertova, Karla Plevova, Sarka Pavlova, Jitka Malcikova, Jana Kotaskova, Kamila Stranska, Michaela Spunarova, Martin Trbusek, Veronika Navrkalova, Barbara Dvorackova, Nikola Tom, Karol Pal, Marie Jarosova, Yvona Brychtova, Anna Panovska, Michael Doubek & Sarka Pospisilova. (2022) Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes. BMC Cancer 22:1.
Crossref
Crossref
Laura Patrussi, Nagaja Capitani & Cosima T. Baldari. (2021) Interleukin (IL)-9 Supports the Tumor-Promoting Environment of Chronic Lymphocytic Leukemia. Cancers 13:24, pages 6301.
Crossref
Crossref
Candida Vitale, Elia Boccellato, Lorenzo Comba, Rebecca Jones, Francesca Perutelli, Valentina Griggio & Marta Coscia. (2021) Impact of Immune Parameters and Immune Dysfunctions on the Prognosis of Patients with Chronic Lymphocytic Leukemia. Cancers 13:15, pages 3856.
Crossref
Crossref
Begüm Alankus, Veronika Ecker, Nathalie Vahl, Martina Braun, Wilko Weichert, Stephan Macher-Göppinger, Torben Gehring, Tanja Neumayer, Thorsten Zenz, Maike Buchner & Jürgen Ruland. (2021) Pathological RANK signaling in B cells drives autoimmunity and chronic lymphocytic leukemia. Journal of Experimental Medicine 218:2.
Crossref
Crossref
Sunil K. Noothi, Mary K. McKenna, Sara S. Alhakeem, James P. Collard, J. T. Greene, Natarajan Muthusamy, Vivek M. Rangnekar & Subbarao Bondada. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
133
148
.
Elena Tibaldi, Enrica Federti, Alessandro Matte, Iana Iatcenko, Anand B. Wilson, Veronica Riccardi, Mario Angelo Pagano & Lucia De Franceschi. (2020) Oxidation Impacts the Intracellular Signaling Machinery in Hematological Disorders. Antioxidants 9:4, pages 353.
Crossref
Crossref
Harry R Haynes & D Simon C Rose. (2019) Synchronous small lymphocytic lymphoma and metastatic breast carcinoma in axillary lymph nodes: Preservation of follicular architecture only in the portions of affected lymph nodes involved by metastatic carcinoma. The Breast Journal 26:2, pages 245-246.
Crossref
Crossref
Sarah Decker, Anabel Zwick, Shifa Khaja Saleem, Sandra Kissel, Andres Rettig, Konrad Aumann & Christine Dierks. (2019) Optimized Xenograft Protocol for Chronic Lymphocytic Leukemia Results in High Engraftment Efficiency for All CLL Subgroups. International Journal of Molecular Sciences 20:24, pages 6277.
Crossref
Crossref
Nagaja Capitani, Giulia Lori, Paolo Paoli, Laura Patrussi, Arianna Troilo, Cosima T. Baldari, Giovanni Raugei & Mario Milco D’Elios. (2019) LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy. Cancer Cell International 19:1.
Crossref
Crossref
Xiaqiu Qiu, Yucheng Tian, Zhuangzhuang Liang, Yujie Sun, Zhiyu Li & Jinlei Bian. (2019) Recent discovery of phosphoinositide 3-kinase γ inhibitors for the treatment of immune diseases and cancers. Future Medicinal Chemistry 11:16, pages 2151-2169.
Crossref
Crossref
Muzammal Hussain, Dickson Adah, Muqddas Tariq, Yongzhi Lu, Jiancun Zhang & Jinsong Liu. (2019) CXCL13/CXCR5 signaling axis in cancer. Life Sciences 227, pages 175-186.
Crossref
Crossref
Ahmed Y. Ali, Xun Wu, Nour Eissa, Sen Hou, Jean-Eric Ghia, Thomas T. Murooka, Versha Banerji, James B. Johnston, Francis Lin, Spencer B. Gibson & Aaron J. Marshall. (2018) Distinct roles for phosphoinositide 3-kinases γ and δ in malignant B cell migration. Leukemia 32:9, pages 1958-1969.
Crossref
Crossref
David K. Edwards V, David Tyler Sweeney, Hibery Ho, Christopher A. Eide, Angela Rofelty, Anupriya Agarwal, Selina Qiuying Liu, Alexey V. Danilov, Patrice Lee, David Chantry, Shannon K. McWeeney, Brian J. Druker, Jeffrey W. Tyner, Stephen E. Spurgeon & Marc M. Loriaux. (2018) Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples. Oncotarget 9:37, pages 24576-24589.
Crossref
Crossref
Laura Patrussi, Nagaja Capitani, Francesca Cattaneo, Noemi Manganaro, Alessandra Gamberucci, Federica Frezzato, Veronica Martini, Andrea Visentin, Pier Giuseppe Pelicci, Mario M. D’Elios, Livio Trentin, Gianpietro Semenzato & Cosima T. Baldari. (2018) p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes. Oncogene 37:11, pages 1534-1550.
Crossref
Crossref
Suliman A. Alsagaby, Paul Brennan & Chris Pepper. (2016) Key Molecular Drivers of Chronic Lymphocytic Leukemia. Clinical Lymphoma Myeloma and Leukemia 16:11, pages 593-606.
Crossref
Crossref
P-P Liu, J Liu, W-Q Jiang, J S Carew, M A Ogasawara, H Pelicano, C M Croce, Z Estrov, R-H Xu, M J Keating & P Huang. (2016) Elimination of chronic lymphocytic leukemia cells in stromal microenvironment by targeting CPT with an antiangina drug perhexiline. Oncogene 35:43, pages 5663-5673.
Crossref
Crossref
Benchang Guo, Lu ZhangNicholas Chiorazzi & Thomas L. Rothstein. (2016) IL-4 rescues surface IgM expression in chronic lymphocytic leukemia. Blood 128:4, pages 553-562.
Crossref
Crossref
Lu Qian Wang, Kwan Yeung Wong, Anders Rosèn & Chor Sang Chim. (2015)
Epigenetic silencing of tumor suppressor
miR-3151
contributes to Chinese chronic lymphocytic leukemia by constitutive activation of MADD/ERK and PIK3R2/AKT signaling pathways
. Oncotarget 6:42, pages 44422-44436.
Crossref
Crossref
Daniela Opel, Andrea Schnaiter, Dagmar Dodier, Marjana Jovanovic, Andreas Gerhardinger, Irina Idler, Daniel Mertens, Lars Bullinger, Stephan Stilgenbauer & Simone Fulda. (2015)
Targeting inhibitor of apoptosis proteins by
S
mac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia
. International Journal of Cancer 137:12, pages 2959-2970.
Crossref
Crossref
Valentina Trimarco, Elisa Ave, Monica Facco, Giorgia Chiodin, Federica Frezzato, Veronica Martini, Cristina Gattazzo, Federica Lessi, Carlo Alberto Giorgi, Andrea Visentin, Monica Castelli, Filippo Severin, Renato Zambello, Francesco Piazza, Gianpietro Semenzato & Livio Trentin. (2015) Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival. Oncotarget 6:39, pages 42130-42149.
Crossref
Crossref
WAN ZHANG, HELENE PELICANO, RAN YIN, JUNYI ZENG, TONG WEN, LU DING & RUIBIN HUANG. (2015) Effective elimination of chronic lymphocytic leukemia cells in the stromal microenvironment by a novel drug combination strategy using redox-mediated mechanisms. Molecular Medicine Reports 12:5, pages 7374-7388.
Crossref
Crossref
Annunziata Gloghini & Italia Bongarzone. (2015) Cell-secreted signals shape lymphoma identity. Seminars in Cancer Biology 34, pages 81-91.
Crossref
Crossref
Antonella Bresin, Elisa Callegari, Lucilla D’Abundo, Caterina Cattani, Cristian Bassi, Barbara Zagatti, M. Grazia Narducci, Elisabetta Caprini, Yuri Pekarsky, Carlo M. Croce, Silvia Sabbioni, Giandomenico Russo & Massimo Negrini. (2015) miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eμ-TCL1 mouse model. Oncotarget 6:23, pages 19807-19818.
Crossref
Crossref
Lu Qian Wang & Chor Sang Chim. (2015) DNA methylation of tumor-suppressor miRNA genes in chronic lymphocytic leukemia. Epigenomics 7:3, pages 461-473.
Crossref
Crossref
M F Huelsemann, M Patz, L Beckmann, K Brinkmann, T Otto, J Fandrey, H J Becker, S Theurich, M von Bergwelt-Baildon, C P Pallasch, R P Zahedi, H Kashkar, H C Reinhardt, M Hallek, C M Wendtner & L P Frenzel. (2014) Hypoxia-induced p38 MAPK activation reduces Mcl-1 expression and facilitates sensitivity towards BH3 mimetics in chronic lymphocytic leukemia. Leukemia 29:4, pages 981-984.
Crossref
Crossref
Nupur Bhattacharya, Michaela Reichenzeller, Maiwen Caudron-Herger, Sarah Haebe, Nathan Brady, Susanne Diener, Maria Nothing, Hartmut Döhner, Stephan Stilgenbauer, Karsten Rippe & Daniel Mertens. (2015) Loss of cooperativity of secreted CD40L and increased dose-response to IL4 on CLL cell viability correlates with enhanced activation of NF-kB and STAT6. International Journal of Cancer 136:1, pages 65-73.
Crossref
Crossref
Kristina Heinig, Marcel Gätjen, Michael Grau, Vanessa Stache, Ioannis Anagnostopoulos, Kerstin Gerlach, Raluca A. Niesner, Zoltan Cseresnyes, Anja E. Hauser, Peter Lenz, Thomas Hehlgans, Robert Brink, Jörg Westermann, Bernd Dörken, Martin Lipp, Georg Lenz, Armin Rehm & Uta E. Höpken. (2014) Access to Follicular Dendritic Cells Is a Pivotal Step in Murine Chronic Lymphocytic Leukemia B-cell Activation and Proliferation. Cancer Discovery 4:12, pages 1448-1465.
Crossref
Crossref
Nathalie Guriec, Catherine Le Jossic- Corcos, Brigitte Simon, Jean-Christophe Ianotto, Adrian Tempescul, Yvonne Dréano, Jean-Pierre Salaün, Christian Berthou & Laurent Corcos. (2014) The arachidonic acid–LTB4–BLT2 pathway enhances human B-CLL aggressiveness. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1842:11, pages 2096-2105.
Crossref
Crossref
Emily Curran & Sonali M. Smith. (2014) Phosphoinositide 3-kinase inhibitors in lymphoma. Current Opinion in Oncology 26:5, pages 469-475.
Crossref
Crossref
Elisabeth WalsbyAndrea Buggins, Stephen Devereux, Ceri JonesGuy Pratt, Paul BrennanChris FeganChris Pepper. (2014) Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia. Blood 123:23, pages 3607-3617.
Crossref
Crossref
Sarah Decker, Johannes Finter, Aaron James Forde, Sandra Kissel, Juerg Schwaller, Thomas Sebastian Mack, Anabel Kuhn, Nathanael Gray, Marie Follo, Hassan Jumaa, Meike Burger, Katja Zirlik, Dietmar Pfeifer, Chandrasekhar V. Miduturu, Hermann Eibel, Hendrik Veelken & Christine Dierks. (2014) PIM Kinases Are Essential for Chronic Lymphocytic Leukemia Cell Survival (PIM2/3) and CXCR4-Mediated Microenvironmental Interactions (PIM1). Molecular Cancer Therapeutics 13:5, pages 1231-1245.
Crossref
Crossref
Maliha Khan, Areeba Saif, Steven Sandler & Aibek E. Mirrakhimov. (2014) Idelalisib for the Treatment of Chronic Lymphocytic Leukemia. ISRN Oncology 2014, pages 1-7.
Crossref
Crossref
Jennifer A. WoyachEngin BojnikAmy S. RuppertMatthew R. StefanovskiVirginia M. GoettlKelly A. SmuckerLisa L. SmithJason A. DubovskyWilliam H. TownsJessica MacMurrayBonnie K. HarringtonMelanie E. DavisStefania GobessiLuca LaurentiBetty Y. Chang, Joseph J. Buggy, Dimitar G. EfremovJohn C. Byrd & Amy J. Johnson. (2014) Bruton’s tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL). Blood 123:8, pages 1207-1213.
Crossref
Crossref
Arnon P. Kater, Marjolein Spiering, Roberto D. Liu, G. Doreen te Raa, E. Slinger, Sanne H. Tonino, Marielle M. Beckers, Simon Daenen, Jeanette K. Doorduijn, Nienke A.G. Lankheet, Dieuwertje M. Luijks, Eric Eldering & Marinus H.J. van Oers. (2014) Dasatinib in combination with fludarabine in patients with refractory chronic lymphocytic leukemia: A multicenter phase 2 study. Leukemia Research 38:1, pages 34-41.
Crossref
Crossref
Tanja Bladt, Claudia Dürr, Peter Knudsen, Sara Kildgaard, Jens Frisvad, Charlotte Gotfredsen, Martina Seiffert & Thomas Larsen. (2013) Bio-Activity and Dereplication-Based Discovery of Ophiobolins and Other Fungal Secondary Metabolites Targeting Leukemia Cells. Molecules 18:12, pages 14629-14650.
Crossref
Crossref
Ranjana Mazumdar, Paul Evans, Rachel Culpin, James Bailey & David Allsup. (2013) The automated monocyte count is independently predictive of overall survival from diagnosis in chronic lymphocytic leukaemia and of survival following first-line chemotherapy. Leukemia Research 37:6, pages 614-618.
Crossref
Crossref
Hussein Ghamlouch, Hakim Ouled-Haddou, Gandhi Damaj, Bruno Royer, Brigitte Gubler & Jean-Pierre Marolleau. (2013) A Combination of Cytokines Rescues Highly Purified Leukemic CLL B-Cells from Spontaneous Apoptosis In Vitro. PLoS ONE 8:3, pages e60370.
Crossref
Crossref
Deepesh P. Lad, Pankaj Malhotra & Subhash Varma. (2012) Chronic Lymphocytic Leukemia: Inception to Cure: Are We There?. Indian Journal of Hematology and Blood Transfusion 29:1, pages 1-10.
Crossref
Crossref
Valentina Audrito, Tiziana Vaisitti, Sara Serra, Cinzia Bologna, Davide Brusa, Fabio Malavasi & Silvia Deaglio. (2013) Targeting the microenvironment in chronic lymphocytic leukemia offers novel therapeutic options. Cancer Letters 328:1, pages 27-35.
Crossref
Crossref
Alessandro Natoni, Michael O’Dwyer & Corrado Santocanale. 2013. Target Identification and Validation in Drug Discovery. Target Identification and Validation in Drug Discovery
217
226
.
Chris Fegan & Chris Pepper. 2013. Advances in Chronic Lymphocytic Leukemia. Advances in Chronic Lymphocytic Leukemia
151
171
.
Nagaja CapitaniLaura PatrussiLivio TrentinOrso Maria LucheriniEnrica CannizzaroEnrica MigliaccioFederica FrezzatoCristina GattazzoFrancesco Forconi, Piergiuseppe PelicciGianpietro SemenzatoCosima T. Baldari. (2012) S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis. Blood 120:22, pages 4391-4399.
Crossref
Crossref
Halina Antosz, Joanna Sajewicz, Barbara Marzec-Kotarska, Dorota Choroszyńska & Anna Dmoszyńska. (2012) Zaburzenia tolerancji endotoksycznej w PBL-B na przykładzie IL-6. Acta Haematologica Polonica 43:2, pages 222-228.
Crossref
Crossref
Jennifer A. Woyach, Amy J. Johnson & John C. Byrd. (2012) The B-cell receptor signaling pathway as a therapeutic target in CLL. Blood 120:6, pages 1175-1184.
Crossref
Crossref
Elisabeth Walsby, Lawrence Pearce, Alan K. Burnett, Chris Fegan & Chris Pepper. (2012) The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-κB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells. Oncotarget 3:5, pages 525-534.
Crossref
Crossref
Wan Zhang, Dunyaporn Trachootham, Jinyun Liu, Gang Chen, Helene Pelicano, Celia Garcia-Prieto, Weiqin Lu, Jan A. Burger, Carlo M. Croce, William Plunkett, Michael J. Keating & Peng Huang. (2012) Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia. Nature Cell Biology 14:3, pages 276-286.
Crossref
Crossref
Sarah DeckerKatja ZirlikLauritte DjebatchieDavid HartmannGabriele Ihorst, Annette Schmitt-GraeffDieter HerchenbachHassan JumaaMarkus Warmuth, Hendrik Veelken & Christine Dierks. (2012) Trisomy 12 and elevated GLI1 and PTCH1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL. Blood 119:4, pages 997-1007.
Crossref
Crossref
Jacqueline M. Tromp, Christian R. Geest, Esther C.W. Breij, Judith A. Elias, Jacoline van Laar, Dieuwertje M. Luijks, Arnon P. Kater, Tim Beaumont, Marinus H.J. van Oers & Eric Eldering. (2012) Tipping the Noxa/Mcl-1 Balance Overcomes ABT-737 Resistance in Chronic Lymphocytic Leukemia. Clinical Cancer Research 18:2, pages 487-498.
Crossref
Crossref
T. Stiehl & A. Marciniak-Czochra. (2012) Mathematical Modeling of Leukemogenesis and Cancer Stem Cell Dynamics. Mathematical Modelling of Natural Phenomena 7:1, pages 166-202.
Crossref
Crossref
John C. Reed. (2011) Priming Cancer Cells for Death. Science 334:6059, pages 1075-1076.
Crossref
Crossref
Sotirios G. PapageorgiouChristos K. Kontos, Vassiliki PappaHellinida Thomadaki, Frida KontsiotiJohn DervenoulasEfstathios PapageorgiouTheofanis EconomopoulosAndreas Scorilas. (2011)
The Novel Member of the
BCL2
Gene Family,
BCL2L12
, Is Substantially Elevated in Chronic Lymphocytic Leukemia Patients, Supporting Its Value As a Significant Biomarker
. The Oncologist 16:9, pages 1280-1291.
Crossref
Crossref
Iris Gehrke, Rajesh Kumar Gandhirajan, Simon Jonas Poll-Wolbeck, Michael Hallek & Karl-Anton Kreuzer. (2011) Bone Marrow Stromal Cell-Derived Vascular Endothelial Growth Factor (VEGF) Rather Than Chronic Lymphocytic Leukemia (CLL) Cell-Derived VEGF Is Essential for the Apoptotic Resistance of Cultured CLL Cells. Molecular Medicine 17:7-8, pages 619-627.
Crossref
Crossref
R. Gitendra Wickremasinghe, Archibald G. Prentice & Andrew J. Steele. (2011) Aberrantly activated anti-apoptotic signalling mechanisms in chronic lymphocytic leukaemia cells: clues to the identification of novel therapeutic targets. British Journal of Haematology 153:5, pages 545-556.
Crossref
Crossref
S H Tonino, J van Laar, M H van Oers, J Y Wang, E Eldering & A P Kater. (2010) ROS-mediated upregulation of Noxa overcomes chemoresistance in chronic lymphocytic leukemia. Oncogene 30:6, pages 701-713.
Crossref
Crossref
Brian J. LannuttiSarah A. MeadowsSarah E. M. Herman, Adam KashishianBart SteinerAmy J. Johnson, John C. Byrd, Jeffrey W. Tyner, Marc M. Loriaux, Mike Deininger, Brian J. Druker, Kamal D. PuriRoger G. UlrichNeill A. Giese. (2011) CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability. Blood 117:2, pages 591-594.
Crossref
Crossref
Martina Seiffert, Angela Schulz, Sibylle Ohl, Hartmut Döhner, Stephan Stilgenbauer & Peter Lichter. (2010) Soluble CD14 is a novel monocyte-derived survival factor for chronic lymphocytic leukemia cells, which is induced by CLL cells in vitro and present at abnormally high levels in vivo. Blood 116:20, pages 4223-4230.
Crossref
Crossref
Medhat Shehata, Susanne SchnablDita DemirtasMartin HilgarthRainer Hubmann, Elena PonathSigrun BadrnyaClaudia LehnerAndrea HoelblMarkus DuechlerAlexander GaigerChristoph Zielinski, Josef D. SchwarzmeierUlrich Jaeger. (2010) Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia. Blood 116:14, pages 2513-2521.
Crossref
Crossref
Andrea G.S. Buggins, Chris Pepper, Piers E.M. Patten, Saman Hewamana, Satyen Gohil, Jane Moorhead, Najeem'deen Folarin, Deborah Yallop, N. Shaun B. Thomas, Ghulam J. Mufti, Chris Fegan & Stephen Devereux. (2010)
Interaction with Vascular Endothelium Enhances Survival in Primary Chronic Lymphocytic Leukemia Cells via NF-κB Activation and
De novo
Gene Transcription
. Cancer Research 70:19, pages 7523-7533.
Crossref
Crossref
J M Tromp, S H Tonino, J A Elias, A Jaspers, D M Luijks, A P Kater, R A W van Lier, M H J van Oers & E Eldering. (2010) Dichotomy in NF-κB signaling and chemoresistance in immunoglobulin variable heavy-chain-mutated versus unmutated CLL cells upon CD40/TLR9 triggering. Oncogene 29:36, pages 5071-5082.
Crossref
Crossref
Andrea G.S. Buggins & Chris J. Pepper. (2010) The role of Bcl-2 family proteins in chronic lymphocytic leukaemia. Leukemia Research 34:7, pages 837-842.
Crossref
Crossref
Simon T. Abrams, Benjamin R. B. Brown, Mirko Zuzel & Joseph R. Slupsky. (2010) Vascular endothelial growth factor stimulates protein kinase CβII expression in chronic lymphocytic leukemia cells. Blood 115:22, pages 4447-4454.
Crossref
Crossref
Nagaja CapitaniOrso Maria LucheriniElisa SozziMicol FerroNico GiommoniFrancesca FinettiGiulia De Falco, Emanuele CenciniDonatella RaspadoriPier Giuseppe Pelicci, Francesco LauriaFrancesco ForconiCosima T. Baldari. (2010) Impaired expression of p66Shc, a novel regulator of B-cell survival, in chronic lymphocytic leukemia. Blood 115:18, pages 3726-3736.
Crossref
Crossref
T Vaisitti, S Aydin, D Rossi, F Cottino, L Bergui, G D'Arena, L Bonello, A L Horenstein, P Brennan, C Pepper, G Gaidano, F Malavasi & S Deaglio. (2010) CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells. Leukemia 24:5, pages 958-969.
Crossref
Crossref
Paula Fernández-Calotti & Marçal Pastor-Anglada. (2010) All-trans-retinoic Acid Promotes Trafficking of Human Concentrative Nucleoside Transporter-3 (hCNT3) to the Plasma Membrane by a TGF-β1-mediated Mechanism. Journal of Biological Chemistry 285:18, pages 13589-13598.
Crossref
Crossref
Rossana Maffei, Silvia Martinelli, Ilaria Castelli, Rita Santachiara, Patrizia Zucchini, Marcella Fontana, Stefania Fiorcari, Goretta Bonacorsi, Fiorella Ilariucci, Giuseppe Torelli & Roberto Marasca. (2010) Increased angiogenesis induced by chronic lymphocytic leukemia B cells is mediated by leukemia-derived Ang2 and VEGF. Leukemia Research 34:3, pages 312-321.
Crossref
Crossref
Amalia Vlad, Pierre-Antoine Deglesne, Rémi Letestu, Stéphane Saint-Georges, Nathalie Chevallier, Fanny Baran-Marszak, Nadine Varin-Blank, Florence Ajchenbaum-Cymbalista & Dominique Ledoux. (2009) Down-regulation of CXCR4 and CD62L in Chronic Lymphocytic Leukemia Cells Is Triggered by B-Cell Receptor Ligation and Associated with Progressive Disease. Cancer Research 69:16, pages 6387-6395.
Crossref
Crossref
Lisa Pleyer, Alexander Egle, Tanja Nicole Hartmann & Richard Greil. (2009) Molecular and cellular mechanisms of CLL: novel therapeutic approaches. Nature Reviews Clinical Oncology 6:7, pages 405-418.
Crossref
Crossref
Matthias Niedermeier, Bryan T. HennessyZachary A. Knight, Marina Henneberg, Jianhua Hu, Antonina V. Kurtova, William G. Wierda, Michael J. Keating, Kevan M. Shokat & Jan A. Burger. (2009) Isoform-selective phosphoinositide 3′-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell–mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach. Blood 113:22, pages 5549-5557.
Crossref
Crossref
Gwendaline Guidicelli, Benjamin Chaigne-Delalande, Marie-Sarah Dilhuydy, Benoît Pinson, Walid Mahfouf, Jean-Max Pasquet, François-Xavier Mahon, Philippe Pourquier, Jean-François Moreau & Patrick Legembre. (2009) The Necrotic Signal Induced by Mycophenolic Acid Overcomes Apoptosis-Resistance in Tumor Cells. PLoS ONE 4:5, pages e5493.
Crossref
Crossref
Anthony Letai. (2009) Hiding from ABT-737 in lymph nodes. Blood 113:18, pages 4132-4133.
Crossref
Crossref
Meike Vogler, Michael Butterworth, Aneela Majid, Renata J. Walewska, Xiao-Ming Sun, Martin J. S. Dyer & Gerald M. Cohen. (2009) Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia. Blood 113:18, pages 4403-4413.
Crossref
Crossref
Jan A. BurgerMaite P. QuirogaElena Hartmann, Andrea Bürkle, William G. WierdaMichael J. KeatingAndreas Rosenwald. (2009) High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation. Blood 113:13, pages 3050-3058.
Crossref
Crossref
Dana S. Levy, Jason A. Kahana & Rakesh Kumar. (2009) AKT inhibitor, GSK690693, induces growth inhibition and apoptosis in acute lymphoblastic leukemia cell lines. Blood 113:8, pages 1723-1729.
Crossref
Crossref
Erica Werner. 2009. Cellular Respiration and Carcinogenesis. Cellular Respiration and Carcinogenesis
161
178
.
Delfine Y. H. Hallaert, Annelieke JaspersCarel J. van Noesel, Marinus H. J. van OersArnon P. KaterEric Eldering. (2008) c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches. Blood 112:13, pages 5141-5149.
Crossref
Crossref
Chris PepperThet Thet LinGuy PrattSaman Hewamana, Paul Brennan, Louise Hiller, Robert HillsRachel WardJane StarczynskiBelinda AustenLaura HooperTatjana StankovicChris Fegan. (2008) Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers. Blood 112:9, pages 3807-3817.
Crossref
Crossref
Liat Nadav, Vyacheslav Kalchenko, Meir Max Barak, Elizabeth Naparstek, Benjamin Geiger & Ben-Zion Katz. (2008) Tumorigenic potential and disease manifestations of malignant B-cell variants differing in their fibronectin adhesiveness. Experimental Hematology 36:11, pages 1524-1534.
Crossref
Crossref
Tomoko Kohno, Tsutomu Daa, Hiroshi Otani, Isao Shimokawa, Shigeo Yokoyama & Toshifumi Matsuyama. (2008) Aberrant expression of BAFF receptor, a member of the tumor necrosis factor receptor family, in malignant cells of nonhematopoietic origins. Genes to Cells 13:10, pages 1061-1073.
Crossref
Crossref
Paula Fernández Calotti, Carlos María Galmarini, Cristian Cañones, Romina Gamberale, Daniel Saénz, Julio Sánchez Avalos, Mónica Chianelli, Ruth Rosenstein & Mirta Giordano. (2008) Modulation of the human equilibrative nucleoside transporter1 (hENT1) activity by IL-4 and PMA in B cells from chronic lymphocytic leukemia. Biochemical Pharmacology 75:4, pages 857-865.
Crossref
Crossref
Marc S. Raab & Kenneth C. Anderson. 2009. Myeloma Therapy. Myeloma Therapy
23
39
.
Constantine S. Mitsiades, Douglas W. McMillin, Steffen Klippel, Teru Hideshima, Dharminder Chauhan, Paul G. Richardson, Nikhil C. Munshi & Kenneth C. Anderson. (2007) The Role of the Bone Marrow Microenvironment in the Pathophysiology of Myeloma and Its Significance in the Development of More Effective Therapies. Hematology/Oncology Clinics of North America 21:6, pages 1007-1034.
Crossref
Crossref
Onoshua Lahiri, Scott Harris, Graham Packham & Melanie Howell. (2007) p53 pathway gene single nucleotide polymorphisms and chronic lymphocytic leukemia. Cancer Genetics and Cytogenetics 179:1, pages 36-44.
Crossref
Crossref
Constantine S. Mitsiades, Nicholas S. Mitsiades, Paul G. Richardson, Nikhil C. Munshi & Kenneth C. Anderson. (2007) Multiple myeloma: A prototypic disease model for the characterization and therapeutic targeting of interactions between tumor cells and their local microenvironment. Journal of Cellular Biochemistry 101:4, pages 950-968.
Crossref
Crossref
Tasneem Motiwala, Sarmila Majumder, Huban Kutay, David Spencer Smith, Donna S. Neuberg, David M. Lucas, John C. Byrd, Michael Grever & Samson T. Jacob. (2007) Methylation and Silencing of Protein Tyrosine Phosphatase Receptor Type O in Chronic Lymphocytic Leukemia. Clinical Cancer Research 13:11, pages 3174-3181.
Crossref
Crossref
Constantine S. Mitsiades, Nicholas S. Mitsiades, Nikhil C. Munshi, Paul G. Richardson & Kenneth C. Anderson. (2006) The role of the bone microenvironment in the pathophysiology and therapeutic management of multiple myeloma: Interplay of growth factors, their receptors and stromal interactions. European Journal of Cancer 42:11, pages 1564-1573.
Crossref
Crossref
Andrew E. SchadeJennifer J. PowersMarcin W. WlodarskiJaroslaw P. Maciejewski. (2006) Phosphatidylinositol-3-phosphate kinase pathway activation protects leukemic large granular lymphocytes from undergoing homeostatic apoptosis. Blood 107:12, pages 4834-4840.
Crossref
Crossref
Anne Mette BuhlJesper JurlanderFlemming S. JørgensenAnne Marie OttesenJack B. CowlandLise Mette GjerdrumBrian V. HansenHenrik Leffers. (2006) Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia. Blood 107:7, pages 2904-2911.
Crossref
Crossref
Paola Secchiero, Federica Corallini, Elisa Barbarotto, Elisabetta Melloni, Maria Grazia di Iasio, Mario Tiribelli & Giorgio Zauli. (2005) Role of the RANKL/RANK system in the induction of interleukin‐8 (IL‐8) in B chronic lymphocytic leukemia (B‐CLL) cells. Journal of Cellular Physiology 207:1, pages 158-164.
Crossref
Crossref
Jennifer S. CarewSteffan T. NawrockiYelena V. KrupnikKenneth DunnerJrJrDavid J. McConkeyMichael J. KeatingPeng Huang. (2006) Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL. Blood 107:1, pages 222-231.
Crossref
Crossref
Xiong-Zhi Wu. (2006) A new classification system of anticancer drugs – Based on cell biological mechanisms. Medical Hypotheses 66:5, pages 883-887.
Crossref
Crossref
Meike BurgerTanja HartmannMyriam KromeJustyna RawlukHirokazu TamamuraNobutaka FujiiThomas J. KippsJan A. Burger. (2005) Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells. Blood 106:5, pages 1824-1830.
Crossref
Crossref