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Original Article

Fructose induced deactivation of antioxidant enzymes: Preventive effect of pyruvate

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Pages 23-30 | Received 13 Oct 1999, Published online: 07 Jul 2009

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Israel Pérez-Torres, Priscilla Roque, Mohammed El Hafidi, Eulises Diaz-Diaz & Guadalupe Baños. (2009) Association of renal damage and oxidative stress in a rat model of metabolic syndrome. Influence of gender. Free Radical Research 43:8, pages 761-771.
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Guadalupe Baños, Omar N Medina-Campos, Perla D Maldonado, José Zamora, Israel Pérez, Natalia Pavón & José Pedraza-Chaverrí. (2005) Antioxidant Enzymes in Hypertensive and Hypertriglyceridemic Rats: Effect of Gender. Clinical and Experimental Hypertension 27:1, pages 45-57.
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Akira Higa, Takako Nakanishi-Ueda, Yuichiro Arai, Tadaharu Tsuchiya, Toshihiko Ueda, Shohei Fukuda, Kaori Watanabe, Kazuaki Kan, Hajime Yasuhara, Ryohei Koide & Donald Armstrong. (2002) Lipid hydroperoxide induced corneal neovascularization in hyperglycemic rabbits. Current Eye Research 25:1, pages 49-53.
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Articles from other publishers (36)

Samreen Amani & Shamila Fatima. (2020) Glycation With Fructose: The Bitter Side of Nature’s Own Sweetener. Current Diabetes Reviews 16:9, pages 962-970.
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Muniza Shaikh, Salman Siddiqui, Humaira Zafar, Uzma Naqeeb, Fakiha Subzwari, Rehan Imad, Khalid M. Khan & Muhammad I. Choudhary. (2020) Antiglycation Activity of Triazole Schiff’s Bases Against Fructosemediated Glycation: In Vitro and In Silico Study. Medicinal Chemistry 16:4, pages 575-591.
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Vladimir I. Muronetz, Aleksandra K. Melnikova, Luciano Saso & Elena V. Schmalhausen. (2020) Influence of Oxidative Stress on Catalytic and Non-glycolytic Functions of Glyceraldehyde-3-phosphate Dehydrogenase. Current Medicinal Chemistry 27:13, pages 2040-2058.
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V. I. Muronetz, A. K. Melnikova, Z. N. Seferbekova, K. V. Barinova & E. V. Schmalhausen. (2017) Glycation, glycolysis, and neurodegenerative diseases: Is there any connection?. Biochemistry (Moscow) 82:8, pages 874-886.
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Alejandro Gugliucci. (2017) Formation of Fructose-Mediated Advanced Glycation End Products and Their Roles in Metabolic and Inflammatory Diseases. Advances in Nutrition 8:1, pages 54-62.
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Hassan Kassassir, Karolina Siewiera, Marcin Talar, Emilia Stec-Martyna, Zofia Pawlowska & Cezary Watala. (2016) Non-enzymatic modifications of prostaglandin H synthase 1 affect bifunctional enzyme activity – Implications for the sensitivity of blood platelets to acetylsalicylic acid. Chemico-Biological Interactions 253, pages 78-92.
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V. Z. Lankin, G. G. Konovalova & A. K. Tikhaze. (2016) Fructose as an inducer of free radical peroxidation of natural lipid-protein supramolecular complexes. Doklady Biochemistry and Biophysics 465:1, pages 398-400.
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S. Ahmad, M. S. Khan, F. Akhter, M. S. Khan, A. Khan, J. M. Ashraf, R. P. Pandey & U. Shahab. (2014) Glycoxidation of biological macromolecules: A critical approach to halt the menace of glycation. Glycobiology 24:11, pages 979-990.
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Izabela Sadowska-Bartosz, Sabina Galiniak & Grzegorz Bartosz. (2014) Kinetics of Glycoxidation of Bovine Serum Albumin by Methylglyoxal and Glyoxal and its Prevention by Various Compounds. Molecules 19:4, pages 4880-4896.
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Rebeca Cambray Guerra, Alejandra Zuñiga-Muñoz, Verónica Guarner Lans, Eulises Díaz-Díaz, Carlos Alberto Tena Betancourt & Israel Pérez-Torres. (2014) Modulation of the Activities of Catalase, Cu-Zn, Mn Superoxide Dismutase, and Glutathione Peroxidase in Adipocyte from Ovariectomised Female Rats with Metabolic Syndrome. International Journal of Endocrinology 2014, pages 1-10.
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Halyna M. Semchyshyn, Jacek Miedzobrodzki, Maria M. Bayliak, Liudmyla M. Lozinska & Bohdana V. Homza. (2014) Fructose compared with glucose is more a potent glycoxidation agent in vitro, but not under carbohydrate-induced stress in vivo: potential role of antioxidant and antiglycation enzymes. Carbohydrate Research 384, pages 61-69.
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Norbert W. SeidlerNorbert W. Seidler. 2013. GAPDH: Biological Properties and Diversity. GAPDH: Biological Properties and Diversity 179 206 .
Mahesh J. Kulkarni, Arvind M. Korwar, Sheon Mary, Hemangi S. Bhonsle & Ashok P. Giri. (2013) Glycated proteome: From reaction to intervention. PROTEOMICS - Clinical Applications 7:1-2, pages 155-170.
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Li Li Wang, Kun Zhang, Chun Yang Xiong & Zi Gang Ge. (2012) Cytotoxicity of core-shell polystyrene magnetic beads and related mechanisms. Molecular & Cellular Toxicology 8:3, pages 217-227.
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Hyun-Ji Kim, Seung-Woo Kim, Ja-Kyeong Lee & Sung-Hwa Yoon. (2011) A Simple and Sensitive High Performance Liquid Chromatography-Electrospray Ionization/Mass Spectrometry Method for the Quantification of Ethyl Pyruvate in Rat Plasma. Bulletin of the Korean Chemical Society 32:4, pages 1221-1227.
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Kristin P. Bibee, Nicholas P. Illsley & Kelle H. Moley. (2011) Asymmetric Syncytial Expression of GLUT9 Splice Variants in Human Term Placenta and Alterations in Diabetic Pregnancies. Reproductive Sciences 18:1, pages 20-27.
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Abhishek Bhattacherjee & Abhay Sankar Chakraborti. (2011) Fructose-induced modifications of myoglobin: Change of structure from met (Fe3+) to oxy (Fe2+) form. International Journal of Biological Macromolecules 48:1, pages 202-209.
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K. R. Hegde, S. Kovtun & Shambhu D. Varma. (2010) Inhibition of glycolysis in the retina by oxidative stress: prevention by pyruvate. Molecular and Cellular Biochemistry 343:1-2, pages 101-105.
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Ann E. Pattin, Sadie Ochs, Christopher S. Theisen, Eugene E. Fibuch & Norbert W. Seidler. (2010) Isoflurane’s effect on interfacial dynamics in GAPDH influences methylglyoxal reactivity. Archives of Biochemistry and Biophysics 498:1, pages 7-12.
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Leone F Mattioli, Naomi B Holloway, James H Thomas & John G Wood. (2010) Fructose, but Not Dextrose, Induces Leukocyte Adherence to the Mesenteric Venule of the Rat by Oxidative Stress. Pediatric Research 67:4, pages 352-356.
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Tania Bose & Abhay Sankar Chakraborti. (2008) Fructose-induced structural and functional modifications of hemoglobin: Implication for oxidative stress in diabetes mellitus. Biochimica et Biophysica Acta (BBA) - General Subjects 1780:5, pages 800-808.
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Mitchell P Fink. (2008) Ethyl pyruvate. Current Opinion in Anaesthesiology 21:2, pages 160-167.
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Susanne Hippeli, Harald Schempp, Erich Elstner & Matthias Elstner. 2008. Free Radicals in Ophthalmic Disorders. Free Radicals in Ophthalmic Disorders 81 105 .
Subhrojit Sen, Tania Bose, Anjana Roy & Abhay Sankar Chakraborti. (2007) Effect of non-enzymatic glycation on esterase activities of hemoglobin and myoglobin. Molecular and Cellular Biochemistry 301:1-2, pages 251-257.
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P. Rajasekar & C. V. Anuradha. (2007) L-Carnitine inhibits protein glycation in vitro and in vivo: evidence for a role in diabetic management. Acta Diabetologica 44:2, pages 83-90.
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M. P. Fink. (2007) Ethyl pyruvate: a novel anti-inflammatory agent. Journal of Internal Medicine 261:4, pages 349-362.
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Shambhu D. VarmaKavita R. Hegde. (2007) Susceptibility of the Ocular Lens to Nitric Oxide: Implications in Cataractogenesis. Journal of Ocular Pharmacology and Therapeutics 23:2, pages 188-195.
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P. Geraldine, B. Brijit Sneha, R. Elanchezhian, E. Ramesh, C.M. Kalavathy, J. Kaliamurthy & P.A. Thomas. (2006) Prevention of selenite-induced cataractogenesis by acetyl-l-carnitine: An experimental study. Experimental Eye Research 83:6, pages 1340-1349.
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Graziela R. Stoppa, Maristela Cesquini, Erika A.F.R. Roman, Satie H. Ogo & Marcio A. Torsoni. (2006) Aminoguanidine prevented impairment of blood antioxidant system in insulin-dependent diabetic rats. Life Sciences 78:12, pages 1352-1361.
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Guadalupe Baños, Omar N Medina-Campos, Perla D Maldonado, José Zamora, Israel Pérez, Natalia Pavón & José Pedraza-Chaverrí. (2005) Activities of antioxidant enzymes in two stages of pathology development in sucrose-fed rats. Canadian Journal of Physiology and Pharmacology 83:3, pages 278-286.
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Casper G. Schalkwijk, Coen D. A. Stehouwer & Victor W. M. van Hinsbergh. (2004) Fructose‐mediated non‐enzymatic glycation: sweet coupling or bad modification. Diabetes/Metabolism Research and Reviews 20:5, pages 369-382.
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Mitchell P. Fink. (2008) The Therapeutic Potential of Ethyl Pyruvate for the Management of Ischemia/Reperfusion Syndromes, Sepsis and Sepsis‐Related Organ Dysfunction, and Other Conditions Associated With Excessive Inflammation. Transfusion Alternatives in Transfusion Medicine 5:4, pages 432-436.
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Yanping LiuHongtao ZhaoHongwei LiB. KalyanaramanAlfred C. NicolosiDavid D. Gutterman. (2003) Mitochondrial Sources of H 2 O 2 Generation Play a Key Role in Flow-Mediated Dilation in Human Coronary Resistance Arteries . Circulation Research 93:6, pages 573-580.
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Mitchell P. Fink. (2003) Ethyl pyruvate: A novel anti-inflammatory agent. Critical Care Medicine 31:Supplement, pages S51-S56.
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M. P. Fink. 2003. Intensive Care Medicine. Intensive Care Medicine 604 614 .
Norbert W Seidler & George S Yeargans. (2002) Effects of thermal denaturation on protein glycation. Life Sciences 70:15, pages 1789-1799.
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