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Original Article

Regulatory mechanisms of cellular response to oxidative stress

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Pages 319-324 | Received 17 Mar 1999, Published online: 07 Jul 2009

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Read on this site (11)

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Crossref
Ilaria Bellezza, Ileana Giambanco, Alba Minelli & Rosario Donato. (2018) Nrf2-Keap1 signaling in oxidative and reductive stress. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865:5, pages 721-733.
Crossref
Xiancheng Qu, Menghong Hu, Yueyong Shang, Lisha Pan, Peixuan Jia, Chunxue Fu, Qigen Liu & Youji Wang. (2018) Liver Transcriptome and miRNA Analysis of Silver Carp (Hypophthalmichthys molitrix) Intraperitoneally Injected With Microcystin-LR. Frontiers in Physiology 9.
Crossref
Esmaeil Dehghan, Yiqiang Zhang, Bahar Saremi, Sivaramakrishna Yadavali, Amirmansoor Hakimi, Maryam Dehghani, Mohammad Goodarzi, Xiaoqin Tu, Scott Robertson, Rueyling Lin, Asish Chudhuri & Hamid Mirzaei. (2017) Hydralazine induces stress resistance and extends C. elegans lifespan by activating the NRF2/SKN-1 signalling pathway. Nature Communications 8:1.
Crossref
Sei-ichiro Motegi, Akiko Sekiguchi, Akihiko Uchiyama, Akihito Uehara, Chisako Fujiwara, Sahori Yamazaki, Buddhini Perera, Hideharu Nakamura, Sachiko Ogino, Yoko Yokoyama, Ryoko Akai, Takao Iwawaki & Osamu Ishikawa. (2017) Protective effect of mesenchymal stem cells on the pressure ulcer formation by the regulation of oxidative and endoplasmic reticulum stress. Scientific Reports 7:1.
Crossref
Sara Petrillo, Emanuela Piermarini, Anna Pastore, Gessica Vasco, Tommaso Schirinzi, Rosalba Carrozzo, Enrico Bertini & Fiorella Piemonte. (2017) Nrf2-Inducers Counteract Neurodegeneration in Frataxin-Silenced Motor Neurons: Disclosing New Therapeutic Targets for Friedreich’s Ataxia. International Journal of Molecular Sciences 18:10, pages 2173.
Crossref
Jinxia Xu, Wei Zhang, Zhongbing Lu, Fang Zhang & Wenjun Ding. (2017) Airborne PM2.5-Induced Hepatic Insulin Resistance by Nrf2/JNK-Mediated Signaling Pathway. International Journal of Environmental Research and Public Health 14:7, pages 787.
Crossref
Sharon Wui Sing Tan, Qian Ying Lee, Belinda Shu Ee Wong, Yu Cai & Gyeong Hun Baeg. (2017) Redox Homeostasis Plays Important Roles in the Maintenance of the Drosophila Testis Germline Stem Cells. Stem Cell Reports 9:1, pages 342-354.
Crossref
Chao Sun, Weiguo Jin & Hongcan Shi. (2017) Oligomeric proanthocyanidins protects A549 cells against H2O2-induced oxidative stress via the Nrf2-ARE pathway. International Journal of Molecular Medicine 39:6, pages 1548-1554.
Crossref
Tetsunari Fukushige, Harold E Smith, Johji Miwa, Michael W Krause & John A Hanover. (2017) A Genetic Analysis of the Caenorhabditis elegans Detoxification Response . Genetics 206:2, pages 939-952.
Crossref
Mina Kim, Sang Yoon Choi, Kyung-Tak Kim, Young Kyoung Rhee & Jinyoung Hur. (2017) Ginsenoside Rg18 suppresses lipopolysaccharide-induced neuroinflammation in BV2 microglia and amyloid-β-induced oxidative stress in SH-SY5Y neurons via nuclear factor erythroid 2-related factor 2/heme oxygenase-1 induction. Journal of Functional Foods 31, pages 71-78.
Crossref
R. Rakowska, A. Sadowska & B. Waszkiewicz-Robak. (2017) Influence of pre- and post-slaughter factors on the reduced glutathione content of beef muscles. Meat Science 124, pages 48-53.
Crossref
Smriti P.K. Mittal, Swati Khole, Nidhi Jagadish, Debjani Ghosh, Vijay Gadgil, Vilas Sinkar & Saroj S. Ghaskadbi. (2016) Andrographolide protects liver cells from H2O2 induced cell death by upregulation of Nrf-2/HO-1 mediated via adenosine A2a receptor signalling. Biochimica et Biophysica Acta (BBA) - General Subjects 1860:11, pages 2377-2390.
Crossref
Bianca Seminotti, Alexandre Umpierrez Amaral, Rafael Teixeira Ribeiro, Marília Danyelle Nunes Rodrigues, Ana Laura Colín-González, Guilhian Leipnitz, Abel Santamaría & Moacir Wajner. (2015) Oxidative Stress, Disrupted Energy Metabolism, and Altered Signaling Pathways in Glutaryl-CoA Dehydrogenase Knockout Mice: Potential Implications of Quinolinic Acid Toxicity in the Neuropathology of Glutaric Acidemia Type I. Molecular Neurobiology 53:9, pages 6459-6475.
Crossref
Alana Pimentel Moura, Belisa Parmeggiani, Mateus Grings, Leonardo de Moura Alvorcem, Rafael Mello Boldrini, Anna Paula Bumbel, Marcela Moreira Motta, Bianca Seminotti, Moacir Wajner & Guilhian Leipnitz. (2015) Intracerebral Glycine Administration Impairs Energy and Redox Homeostasis and Induces Glial Reactivity in Cerebral Cortex of Newborn Rats. Molecular Neurobiology 53:9, pages 5864-5875.
Crossref
Kyeojin Kim, Jong-Min Park, Nam-Jung Kim, Su-Jung Kim, Hyunyoung Moon, Hongchan An, Jeeyeon Lee, Hyun-Ju Park, Young-Joon Surh & Young-Ger Suh. (2016) Identification and Structural Analysis of New Nrf2 Activators by Mechanism-Based Chemical Transformation of 15-Deoxy-Δ 12, 14 -PGJ 2 . ChemBioChem 17:20, pages 1900-1904.
Crossref
Mohammad Raish, Ajaz Ahmad, Basit L. Jan, Khalid M. Alkharfy, Mushtaq Ahmad Ansari, Kazi Mohsin, Fahad al Jenoobi & Abdullah Al-Mohizea. (2016) Momordica charantia polysaccharides mitigate the progression of STZ induced diabetic nephropathy in rats. International Journal of Biological Macromolecules 91, pages 394-399.
Crossref
Jiayu Zhu, Huihui Wang, Feng Chen, Jingqi Fu, Yuanyuan Xu, Yongyong Hou, Henry H. Kou, Cheng Zhai, M. Bud Nelson, Qiang Zhang, Melvin E. Andersen & Jingbo Pi. (2016) An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy. Free Radical Biology and Medicine 99, pages 544-556.
Crossref
Pu-Rong Chiu, Yu-Chen Hu, Bau-Shan Hsieh, Tzu-Ching Huang, Hsiao-Ling Cheng, Li-Wen Huang & Kee-Lung Chang. (2016) Osteoblasts activate the Nrf2 signalling pathway in response to arsenic trioxide treatment. The International Journal of Biochemistry & Cell Biology 79, pages 327-336.
Crossref
Subhash Dwivedi, N. Rajasekar, Kashif Hanif, Chandishwar Nath & Rakesh Shukla. (2015) Sulforaphane Ameliorates Okadaic Acid-Induced Memory Impairment in Rats by Activating the Nrf2/HO-1 Antioxidant Pathway. Molecular Neurobiology 53:8, pages 5310-5323.
Crossref
Akihiko Uchiyama, Kazuya Yamada, Buddhini Perera, Sachiko Ogino, Yoko Yokoyama, Yuko Takeuchi, Osamu Ishikawa & Sei-ichiro Motegi. (2016) Topical betamethasone butyrate propionate exacerbates pressure ulcers after cutaneous ischemia-reperfusion injury. Experimental Dermatology 25:9, pages 678-683.
Crossref
Mária Maslaňáková, Lucia Balogová, Pavol Miškovský, Ružena Tkáčová & Katarína Štroffeková. (2016) Anti- and Pro-apoptotic Bcl2 Proteins Distribution and Metabolic Profile in Human Coronary Aorta Endothelial Cells Before and After HypPDT. Cell Biochemistry and Biophysics 74:3, pages 435-447.
Crossref
E. Mazur, K. Sieron-Stoltny, G. Cieslar, A. Sieron & P. Sowa. (2016) Impact of electromagnetic field generated by mobile phone on prooxidant-antioxidant balance in testes of rats. Impact of electromagnetic field generated by mobile phone on prooxidant-antioxidant balance in testes of rats.
Britney Johnson, Jing Li, Jagat Adhikari, Megan R. Edwards, Hao Zhang, Toni Schwarz, Daisy W. Leung, Christopher F. Basler, Michael L. Gross & Gaya K. Amarasinghe. (2016) Dimerization Controls Marburg Virus VP24-dependent Modulation of Host Antioxidative Stress Responses. Journal of Molecular Biology 428:17, pages 3483-3494.
Crossref
Shinya Toyokuni. (2016) The origin and future of oxidative stress pathology: From the recognition of carcinogenesis as an iron addiction with ferroptosis‐resistance to non‐thermal plasma therapy. Pathology International 66:5, pages 245-259.
Crossref
Elango Bhakkiyalakshmi, Dornadula Sireesh, Murugesan Sakthivadivel, Srinivasan Sivasubramanian, Palani Gunasekaran & Kunka Mohanram Ramkumar. (2016) Anti-hyperlipidemic and anti-peroxidative role of pterostilbene via Nrf2 signaling in experimental diabetes. European Journal of Pharmacology 777, pages 9-16.
Crossref
Sangeetha Sukumari-Ramesh & Cargill H. AlleyneJrJr. (2016) Post-Injury Administration of Tert-butylhydroquinone Attenuates Acute Neurological Injury After Intracerebral Hemorrhage in Mice. Journal of Molecular Neuroscience 58:4, pages 525-531.
Crossref
Volodymyr I. Lushchak. (2015) Contaminant-induced oxidative stress in fish: a mechanistic approach. Fish Physiology and Biochemistry 42:2, pages 711-747.
Crossref
Brittany C. Lipchick, Emily E. Fink & Mikhail A. Nikiforov. (2016) Oxidative stress and proteasome inhibitors in multiple myeloma. Pharmacological Research 105, pages 210-215.
Crossref
Takemi Yoshida, Takashi Ashino & Yasuna Kobayashi. (2016) Chemical-induced coordinated and reciprocal changes in heme metabolism, cytochrome P450 synthesis and others in the liver of humans and rodents. The Journal of Toxicological Sciences 41:Special, pages SP89-SP103.
Crossref
Yumi Abiko, Fang-Yu Lin, Hsinyu Lee, Alvaro Puga & Yoshito Kumagai. (2016) Quinone-mediated induction of cytochrome P450 1A1 in HepG2 cells through increased interaction of aryl hydrocarbon receptor with aryl hydrocarbon receptor nuclear translocator. The Journal of Toxicological Sciences 41:6, pages 775-781.
Crossref
Regina Medvedev, Daniela Ploen & Eberhard Hildt. (2016) HCV and Oxidative Stress: Implications for HCV Life Cycle and HCV-Associated Pathogenesis. Oxidative Medicine and Cellular Longevity 2016, pages 1-13.
Crossref
Hongquan Wang, Yumin Wang, Linan Zhao, Qifu Cui, Yuehua Wang & Guanhua Du. (2016) Pinocembrin attenuates MPP + -induced neurotoxicity by the induction of heme oxygenase-1 through ERK1/2 pathway. Neuroscience Letters 612, pages 104-109.
Crossref
Kaitlyn N. Lewis & Rochelle Buffenstein. 2016. Handbook of the Biology of Aging. Handbook of the Biology of Aging 179 204 .
Li Li, Jikun Du, Yaru Lian, Yun Zhang, Xingren Li, Ying Liu, Liyi Zou & Tie Wu. (2015) Protective Effects of Coenzyme Q10 Against Hydrogen Peroxide-Induced Oxidative Stress in PC12 Cell: The Role of Nrf2 and Antioxidant Enzymes. Cellular and Molecular Neurobiology 36:1, pages 103-111.
Crossref
Sangeetha Sukumari-Ramesh, Niyathi Prasad, Cargill H AlleyneJrJr, John R Vender & Krishnan M Dhandapani. (2015) Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells. BMC Cancer 15:1.
Crossref
Ajeet Kumar Verma, Arti Yadav, Jayant Dewangan, Sarvendra Vikram Singh, Manisha Mishra, Pradhyumna Kumar Singh & Srikanta Kumar Rath. (2015) Isoniazid prevents Nrf2 translocation by inhibiting ERK1 phosphorylation and induces oxidative stress and apoptosis. Redox Biology 6, pages 80-92.
Crossref
Tao Jiang, Bryan Harder, Montserrat Rojo de la Vega, Pak K. Wong, Eli Chapman & Donna D. Zhang. (2015) p62 links autophagy and Nrf2 signaling. Free Radical Biology and Medicine 88, pages 199-204.
Crossref
Takafumi Suzuki & Masayuki Yamamoto. (2015) Molecular basis of the Keap1–Nrf2 system. Free Radical Biology and Medicine 88, pages 93-100.
Crossref
Raquel R. Bartz, Hagir B. Suliman & Claude A. Piantadosi. (2015) Redox mechanisms of cardiomyocyte mitochondrial protection. Frontiers in Physiology 6.
Crossref
Vera L. Bonilha, Brent A. Bell, Mary E. Rayborn, Xiaoping Yang, Charlie Kaul, Gregory H. Grossman, Ivy S. Samuels, Joe G. Hollyfield, Chengsong Xie, Huaibin Cai & Karen G. Shadrach. (2015) Loss of DJ-1 elicits retinal abnormalities, visual dysfunction, and increased oxidative stress in mice. Experimental Eye Research 139, pages 22-36.
Crossref
Takeshi Kumagai, Yosuke Kozakai, Tomohiro Ishino, Yuichi Yajima, Yasuhito Nakagawa & Hirotaka Imai. (2015) Nrf2 up-regulates the induction of acidic sphingomyelinase by electrophiles. Journal of Biochemistry 158:2, pages 127-137.
Crossref
Ivraj Singh SandhuNicholas James MaksimEva Alice AmouzouganBryce Wilson GallionAnthony L.J. RavieleAikseng Ooi. (2015) Sustained NRF2 activation in hereditary leiomyomatosis and renal cell cancer (HLRCC) and in hereditary tyrosinemia type 1 (HT1). Biochemical Society Transactions 43:4, pages 650-656.
Crossref
Yang Yang, Gang Chen, Xiaolan Cheng, Zhiying Teng, Xueting Cai, Jie Yang, Xiaoyan Sun, Wuguang Lu, Xiaoning Wang, Yuanzhang Yao, Chunping Hu & Peng Cao. (2015) Therapeutic potential of digitoflavone on diabetic nephropathy: nuclear factor erythroid 2-related factor 2-dependent anti-oxidant and anti-inflammatory effect. Scientific Reports 5:1.
Crossref
Xian Hua Xu, Gai Li Li, Bing Ang Wang, Yang Qin, Shu Rong Bai, Jian Rong, Tao Deng & Qiang Li. (2015) Diallyl trisufide protects against oxygen glucose deprivation -induced apoptosis by scavenging free radicals via the PI3K/Akt -mediated Nrf2/HO-1 signaling pathway in B35 neural cells. Brain Research 1614, pages 38-50.
Crossref
Shan Cao, Dongman Chao, Honghao Zhou, Gianfranco Balboni & Ying Xia. (2015) A novel mechanism for cytoprotection against hypoxic injury: δ-opioid receptor-mediated increase in Nrf2 translocation. British Journal of Pharmacology 172:7, pages 1869-1881.
Crossref
Kaitlyn N. LewisEmily Wason, Yael H. EdreyDeborah M. Kristan, Eviatar Nevo & Rochelle Buffenstein. (2015) Regulation of Nrf2 signaling and longevity in naturally long-lived rodents. Proceedings of the National Academy of Sciences 112:12, pages 3722-3727.
Crossref
Y. J. Lee, S. B. Kwon, J. M. An, C. H. Kim, S. H. Lee, C. Y. Choi, D. H. Nam, J. W. Park, H. S. Nam, S. H. Lee, M. W. Lee & M. K. Cho. (2015) Increased protein oxidation and decreased expression of nuclear factor E2-related factor 2 protein in skin tissue of patients with diabetes. Clinical and Experimental Dermatology 40:2, pages 192-200.
Crossref
Eui Jung Moon & Amato Giaccia. (2015) Dual roles of NRF2 in tumor prevention and progression: Possible implications in cancer treatment. Free Radical Biology and Medicine 79, pages 292-299.
Crossref
Mona Connolly, María Luisa Fernández-Cruz & José María Navas. (2015) Recovery of redox homeostasis altered by CuNPs in H4IIE liver cells does not reduce the cytotoxic effects of these NPs: An investigation using aryl hydrocarbon receptor (AhR) dependent antioxidant activity. Chemico-Biological Interactions 228, pages 57-68.
Crossref
Yoon Jin LeeSun Bum KwonChul Han KimHyun Deuk ChoHae Seon NamSang Han LeeMi Woo LeeDoo Hyun NamChang Yong ChoiMoon Kyun Cho. (2015) Oxidative Damage and Nuclear Factor Erythroid 2-Related Factor 2 Protein Expression in Normal Skin and Keloid Tissue. Annals of Dermatology 27:5, pages 507.
Crossref
Pan Gao, Liliang Li, Lili Ji, Yingze Wei, Hui Li, Guoguo Shang, Zhonghua Zhao, Qi Chen, Tao Jiang & Nong Zhang. (2014) Nrf2 ameliorates diabetic nephropathy progression by transcriptional repression of TGFβ1 through interactions with c-Jun and SP1. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1839:11, pages 1110-1120.
Crossref
Daniela Lucchesi, Rossella Russo, Morena Gabriele, Vincenzo Longo, Stefano Del Prato, Giuseppe Penno & Laura Pucci. (2014) Grain and Bean Lysates Improve Function of Endothelial Progenitor Cells from Human Peripheral Blood: Involvement of the Endogenous Antioxidant Defenses. PLoS ONE 9:10, pages e109298.
Crossref
Lenka Dzurová, Dana Petrovajova, Zuzana Nadova, Veronika Huntosova, Pavol Miskovsky & Katarina Stroffekova. (2014) The role of anti-apoptotic protein kinase Cα in response to hypericin photodynamic therapy in U-87 MG cells. Photodiagnosis and Photodynamic Therapy 11:2, pages 213-226.
Crossref
Kuo-Hsuan Chang, Wan-Ling Chen, Yih-Ru Wu, Te-Hsien Lin, Yi-Ci Wu, Chih-Ying Chao, Jung-Yaw Lin, Li-Ching Lee, Yi-Chun Chen, Guey-Jen Lee-Chen & Chiung-Mei Chen. (2014) Aqueous extract of Gardenia jasminoides targeting oxidative stress to reduce polyQ aggregation in cell models of spinocerebellar ataxia 3. Neuropharmacology 81, pages 166-175.
Crossref
Graziano Colombo, Marco Clerici, Daniela Giustarini, Nicola M. Portinaro, Giancarlo Aldini, Ranieri Rossi, Aldo Milzani & Isabella Dalle-Donne. (2014) Pathophysiology of tobacco smoke exposure: Recent insights from comparative and redox proteomics. Mass Spectrometry Reviews 33:3, pages 183-218.
Crossref
Elango Bhakkiyalakshmi, Devibalan Shalini, Thillai Veerapazham Sekar, Palanisamy Rajaguru, Ramasamy Paulmurugan & Kunka Mohanram Ramkumar. (2014) Therapeutic potential of pterostilbene against pancreatic beta-cell apoptosis mediated through Nrf2. British Journal of Pharmacology 171:7, pages 1747-1757.
Crossref
A.L. Colín-González, A. Luna-López, M. Königsberg, S.F. Ali, J. Pedraza-Chaverrí & A. Santamaría. (2014) Early modulation of the transcription factor Nrf2 in rodent striatal slices by quinolinic acid, a toxic metabolite of the kynurenine pathway. Neuroscience 260, pages 130-139.
Crossref
Susan A. Farr, Jessica L. Ripley, Rukhsana Sultana, Zhaoshu Zhang, Michael L. Niehoff, Thomas L. Platt, M. Paul Murphy, John E. Morley, Vijaya Kumar & D. Allan Butterfield. (2014) Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease. Free Radical Biology and Medicine 67, pages 387-395.
Crossref
B. O. Akanbi & O. O. Agarry. (2014) Hypocholesterolemic and Growth Promoting Effects of <i>Lactobacillus plantarum</i> AK Isolated from a Nigerian Fermented Cereal Product on Rats Fed High Fat Diet. Advances in Microbiology 04:03, pages 160-166.
Crossref
Tao Jiang, Fei Tian, Hongting Zheng, Samantha A. Whitman, Yifeng Lin, Zhigang Zhang, Nong Zhang & Donna D. Zhang. (2014) Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory response. Kidney International 85:2, pages 333-343.
Crossref
Brian J. Day. (2014) Antioxidant therapeutics: Pandora′s box. Free Radical Biology and Medicine 66, pages 58-64.
Crossref
Thomas Wyche, Miranda Standiford, Yanpeng Hou, Doug Braun, Delinda Johnson, Jeffrey Johnson & Tim Bugni. (2013) Activation of the Nuclear Factor E2-Related Factor 2 Pathway by Novel Natural Products Halomadurones A–D and a Synthetic Analogue. Marine Drugs 11:12, pages 5089-5099.
Crossref
Jialin Xu, Ajay C. Donepudi, Jamie E. Moscovitz & Angela L. Slitt. (2013) Keap1-Knockdown Decreases Fasting-Induced Fatty Liver via Altered Lipid Metabolism and Decreased Fatty Acid Mobilization from Adipose Tissue. PLoS ONE 8:11, pages e79841.
Crossref
Mary Morada, Lakhsmi Pendyala, Gang Wu, Salim Merali & Nigel Yarlett. (2013) Cryptosporidium parvum Induces an Endoplasmic Stress Response in the Intestinal Adenocarcinoma HCT-8 Cell Line. Journal of Biological Chemistry 288:42, pages 30356-30364.
Crossref
Andrew V. Stachulski, Thomas A. Baillie, B. Kevin Park, R. Scott Obach, Deepak K. Dalvie, Dominic P. Williams, Abhishek Srivastava, Sophie L. Regan, Daniel J. Antoine, Christopher E. P. Goldring, Alvin J. L. Chia, Neil R. Kitteringham, Laura E. Randle, Hayley Callan, J. Luis Castrejon, John Farrell, Dean J. Naisbitt & Martin S. Lennard. (2013) The Generation, Detection, and Effects of Reactive Drug Metabolites. Medicinal Research Reviews 33:5, pages 985-1080.
Crossref
Annmarie Ramkissoon, Aaron M. Shapiro, Margaret M. Loniewska & Peter G. Wells. 2013. Molecular Basis of Oxidative Stress. Molecular Basis of Oxidative Stress 237 310 .
Shu Wang, Hao Zhang, Weiwei Zheng, Xia Wang, Melvin E. Andersen, Jingbo Pi, Gengsheng He & Weidong Qu. (2013) Organic Extract Contaminants from Drinking Water Activate Nrf2-Mediated Antioxidant Response in a Human Cell Line. Environmental Science & Technology 47:9, pages 4768-4777.
Crossref
Cheong-Meng Chong, Zhong-Yan Zhou, Valentina Razmovski-Naumovski, Guo-Zhen Cui, Lun-Qing Zhang, Fei Sa, Pui-Man Hoi, Kelvin Chan & Simon Ming-Yuen Lee. (2013) Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish. Neuroscience Letters 543, pages 121-125.
Crossref
ZHENBO ZHANG, QIANQIAN WANG, JIE MA, XIAOFANG YI, YAPING ZHU, XIAOWEI XI, YOUJI FENG & ZHIJUN JIN. (2013) Reactive oxygen species regulate FSH-induced expression of vascular endothelial growth factor via Nrf2 and HIF1α signaling in human epithelial ovarian cancer. Oncology Reports 29:4, pages 1429-1434.
Crossref
Guangyu Li, Dan Shen, Xu‐Fang Liang, Yan He & Shan He. (2011) Effects of malachite green on the mRNA expression of detoxification‐related genes in Nile tilapia ( Oreochromis niloticus ) and other major Chinese freshwater fishes . Environmental Toxicology 28:3, pages 137-145.
Crossref
Li Li, Ji-kun Du, Li-yi Zou, Tie Wu, Yong-woo Lee & Yong-ho Kim. (2013) Decursin Isolated from Angelica gigas Nakai Rescues PC12 Cells from Amyloid -Protein-Induced Neurotoxicity through Nrf2-Mediated Upregulation of Heme Oxygenase-1: Potential Roles of MAPK . Evidence-Based Complementary and Alternative Medicine 2013, pages 1-14.
Crossref
Amit K. Maiti. 2013. Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy. Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy 135 149 .
Jialin Xu, Supriya R. Kulkarni, Ajay C. Donepudi, Vijay R. More & Angela L. Slitt. (2012) Enhanced Nrf2 Activity Worsens Insulin Resistance, Impairs Lipid Accumulation in Adipose Tissue, and Increases Hepatic Steatosis in Leptin-Deficient Mice. Diabetes 61:12, pages 3208-3218.
Crossref
Steven G. Kelsen. (2012) Respiratory epithelial cell responses to cigarette smoke: The unfolded protein response. Pulmonary Pharmacology & Therapeutics 25:6, pages 447-452.
Crossref
Julio César Tobón-Velasco, Genaro Vázquez-Victorio, Marina Macías-Silva, Elvis Cuevas, Syed F. Ali, Perla D. Maldonado, María Eva González-Trujano, Antonio Cuadrado, José Pedraza-Chaverrí & Abel Santamaría. (2012) RETRACTED: S-allyl cysteine protects against 6-hydroxydopamine-induced neurotoxicity in the rat striatum: Involvement of Nrf2 transcription factor activation and modulation of signaling kinase cascades. Free Radical Biology and Medicine 53:5, pages 1024-1040.
Crossref
Tharine Dal-Cim, Simone Molz, Javier Egea, Esther Parada, Alejandro Romero, Josiane Budni, Maria D. Martín de Saavedra, Laura del Barrio, Carla I. Tasca & Manuela G. López. (2012) Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway. Neurochemistry International 61:3, pages 397-404.
Crossref
Mei Shan Piao, Jae-Jeong Park, Jee-Young Choi, Dong-Hoon Lee, Sook Jung Yun, Jee-Bum Lee & Seung-Chul Lee. (2012) Nrf2-dependent and Nrf2-independent induction of phase 2 detoxifying and antioxidant enzymes during keratinocyte differentiation. Archives of Dermatological Research 304:5, pages 387-395.
Crossref
Yu-Chen Hu, Hsiao-Ling Cheng, Bau-Shan Hsieh, Li-Wen Huang, Tzu-Ching Huang & Kee-Lung Chang. (2012) Arsenic trioxide affects bone remodeling by effects on osteoblast differentiation and function. Bone 50:6, pages 1406-1415.
Crossref
Hongqiao Zhang, Honglei Liu, Kelvin J.A. Davies, Constantinos Sioutas, Caleb E. Finch, Todd E. Morgan & Henry Jay Forman. (2012) Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments. Free Radical Biology and Medicine 52:9, pages 2038-2046.
Crossref
Akshaya K. Meher, Poonam R. Sharma, Vitor A. Lira, Masayuki Yamamoto, Thomas W. Kensler, Zhen Yan & Norbert Leitinger. (2012) Nrf2 deficiency in myeloid cells is not sufficient to protect mice from high-fat diet-induced adipose tissue inflammation and insulin resistance. Free Radical Biology and Medicine 52:9, pages 1708-1715.
Crossref
Hong-Quan Wang, Yu-Xia Xu & Cui-Qing Zhu. (2011) Upregulation of Heme Oxygenase-1 by Acteoside Through ERK and PI3 K/Akt Pathway Confer Neuroprotection Against Beta-Amyloid-Induced Neurotoxicity. Neurotoxicity Research 21:4, pages 368-378.
Crossref
Jung-Hoon Yoon, Hyo-Eun Yoon, Ok Kim, Sang Kyum Kim, Sang-Gun Ahn & Keon Wook Kang. (2012) The enhanced anti-cancer effect of hexenyl ester of 5-aminolaevulinic acid photodynamic therapy in adriamycin-resistant compared to non-resistant breast cancer cells. Lasers in Surgery and Medicine 44:1, pages 76-86.
Crossref
Carisa Tilton, Amy J. Clippinger, Tobi Maguire & James C. Alwine. (2011) Human Cytomegalovirus Induces Multiple Means To Combat Reactive Oxygen Species. Journal of Virology 85:23, pages 12585-12593.
Crossref
Tomofumi Hoshino, Keiji Tabuchi, Bungo Nishimura, Shuho Tanaka, Masahiro Nakayama, Tetsuro Ishii, Eiji Warabi, Toru Yanagawa, Ritsuku Shimizu, Masayuki Yamamoto & Akira Hara. (2011) Protective role of Nrf2 in age-related hearing loss and gentamicin ototoxicity. Biochemical and Biophysical Research Communications 415:1, pages 94-98.
Crossref
Ayako Hirota, Yasuhiro Kawachi, Masayuki Yamamoto, Tsutomu Koga, Kazuhiko Hamada & Fujio Otsuka. (2011) Acceleration of UVB-induced photoageing in nrf2 gene-deficient mice. Experimental Dermatology 20:8, pages 664-668.
Crossref
Madhumohan R. Katika, Peter J.M. Hendriksen, Henk van Loveren & Ad Peijnenburg. (2011) Exposure of Jurkat cells to bis (tri-n-butyltin) oxide (TBTO) induces transcriptomics changes indicative for ER- and oxidative stress, T cell activation and apoptosis. Toxicology and Applied Pharmacology 254:3, pages 311-322.
Crossref
Brooks M. Hybertson, Bifeng Gao, Swapan K. Bose & Joe M. McCord. (2011) Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation. Molecular Aspects of Medicine 32:4-6, pages 234-246.
Crossref
Huangyuan Li, Siying Wu, Nian Shi, Wei Lin, Junyi You & Wenhua Zhou. (2010) NF-E2-related factor 2 activation in PC12 cells: its protective role in manganese-induced damage. Archives of Toxicology 85:8, pages 901-910.
Crossref
Zhe Jian, Kai Li, Ling Liu, Ying Zhang, Zhou Zhou, Chunying Li & Tianwen Gao. (2011) Heme Oxygenase-1 Protects Human Melanocytes from H2O2-Induced Oxidative Stress via the Nrf2-ARE Pathway. Journal of Investigative Dermatology 131:7, pages 1420-1427.
Crossref
Agnieszka JazwaAna I. RojoNadia G. InnamoratoMarlen HesseJavier Fernández-RuizAntonio Cuadrado. (2011) Pharmacological Targeting of the Transcription Factor Nrf2 at the Basal Ganglia Provides Disease Modifying Therapy for Experimental Parkinsonism. Antioxidants & Redox Signaling 14:12, pages 2347-2360.
Crossref
Su Jin Kang, Aram You & Mi-Kyoung Kwak. (2011) Suppression of Nrf2 signaling by angiotensin II in murine renal epithelial cells. Archives of Pharmacal Research 34:5, pages 829-836.
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David M Duda, Daniel C Scott, Matthew F Calabrese, Erik S Zimmerman, Ning Zheng & Brenda A Schulman. (2011) Structural regulation of cullin-RING ubiquitin ligase complexes. Current Opinion in Structural Biology 21:2, pages 257-264.
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Aiqing Li, Yun-Sik Choi, Heather Dziema, Ruifeng Cao, Hee-Yeon Cho, Yeon Joo Jung & Karl Obrietan. (2010) Proteomic Profiling of the Epileptic Dentate Gyrus. Brain Pathology 20:6, pages 1077-1089.
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Yoon Mee Yang, Kyoung Noh, Chang Yeob Han & Sang Geon Kim. (2010) Transactivation of Genes Encoding for Phase II Enzymes and Phase III Transporters by Phytochemical Antioxidants. Molecules 15:9, pages 6332-6348.
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Sahoko IchiharaYoshiji YamadaFang LiuToyoaki MuroharaKen ItohMasayuki YamamotoGaku Ichihara. (2010) Ablation of the Transcription Factor Nrf2 Promotes Ischemia-Induced Neovascularization by Enhancing the Inflammatory Response. Arteriosclerosis, Thrombosis, and Vascular Biology 30:8, pages 1553-1561.
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Annalaura Mancia, Gregory W. Warr, Jonas S. Almeida, Artur Veloso, Randall S. Wells & Robert W. Chapman. (2010) Transcriptome Profiles: Diagnostic Signature of Dolphin Populations. Estuaries and Coasts 33:4, pages 919-929.
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Tsuyoshi Takahashi, Makoto Sonobe, Toshi Menju, Ei Nakayama, Nobuya Mino, Shotaro Iwakiri, Shinjiro Nagai, Kiyoshi Sato, Ryo Miyahara, Kenichi Okubo, Toshiki Hirata, Hiroshi Date & Hiromi Wada. (2010) Mutations in Keap1 are a potential prognostic factor in resected non‐small cell lung cancer. Journal of Surgical Oncology 101:6, pages 500-506.
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Tao JiangZheping HuangYifeng LinZhigang ZhangDeyu FangDonna D. Zhang. (2010) The Protective Role of Nrf2 in Streptozotocin-Induced Diabetic Nephropathy. Diabetes 59:4, pages 850-860.
Crossref
Hye-Youn Cho & Steven R. Kleeberger. (2010) Nrf2 protects against airway disorders. Toxicology and Applied Pharmacology 244:1, pages 43-56.
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Natalia V. Zhukova, Yulia K. Karaman & Natalia V. Zhukova. (2010) The effect of high fat food on erythrocyte phospholipids, fatty acids composition and glutathione redox-system of rats with alimentary dyslipidemia. Health 02:01, pages 45-50.
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Tomohisa Takagi, Yuji Naito, Hitomi Okada, Takeshi Ishii, Katsura Mizushima, Satomi Akagiri, Satoko Adachi, Osamu Handa, Satoshi Kokura, Hiroshi Ichikawa, Ken Itoh, Masayuki Yamamoto, Hirofumi Matsui & Toshikazu Yoshikawa. (2009) Lansoprazole, a Proton Pump Inhibitor, Mediates Anti-Inflammatory Effect in Gastric Mucosal Cells through the Induction of Heme Oxygenase-1 via Activation of NF-E2-Related Factor 2 and Oxidation of Kelch-Like ECH-Associating Protein 1. Journal of Pharmacology and Experimental Therapeutics 331:1, pages 255-264.
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Samuel Carroll BrooksIIIIII, Janie Sue Brooks, Woo Hyung Lee, Myung Gull Lee & Sang Geon Kim. (2009) Therapeutic potential of dithiolethiones for hepatic diseases. Pharmacology & Therapeutics 124:1, pages 31-43.
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Smadar Levy, Anil K. Jaiswal & Henry Jay Forman. (2009) The role of c-Jun phosphorylation in EpRE activation of phase II genes. Free Radical Biology and Medicine 47:8, pages 1172-1179.
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