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Original Articles

Pesticide Exposures and Developmental Outcomes: The Epidemiological Evidence

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Pages 41-80 | Published online: 10 Dec 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Judy S LaKind, Laura G Anthony & Michael Goodman. (2017) Review of reviews on exposures to synthetic organic chemicals and children’s neurodevelopment: Methodological and interpretation challenges. Journal of Toxicology and Environmental Health, Part B 20:8, pages 390-422.
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Darío A. Maggioni, Marcelo L. Signorini, Nicolás Michlig, María R. Repetti, Mirna E. Sigrist & Horacio R. Beldomenico. (2017) Comprehensive estimate of the theoretical maximum daily intake of pesticide residues for chronic dietary risk assessment in Argentina. Journal of Environmental Science and Health, Part B 52:4, pages 256-266.
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Carol J. Burns, Laura J. McIntosh, Pamela J. Mink, Anne M. Jurek & Abby A. Li. (2013) Pesticide Exposure and Neurodevelopmental Outcomes: Review of the Epidemiologic and Animal Studies. Journal of Toxicology and Environmental Health, Part B 16:3-4, pages 127-283.
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Pamela J. Mink, Carole A. Kimmel & Abby A. Li. (2012) Potential Effects of Chlorpyrifos on Fetal Growth Outcomes: Implications for Risk Assessment. Journal of Toxicology and Environmental Health, Part B 15:4, pages 281-316.
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Abby A. Li, Kimberly A. Lowe, Laura J. McIntosh & Pamela J. Mink. (2012) Evaluation of Epidemiology and Animal Data for Risk Assessment: Chlorpyrifos Developmental Neurobehavioral Outcomes. Journal of Toxicology and Environmental Health, Part B 15:2, pages 109-184.
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Anne-Simone Parent, Elise Naveau, Arlette Gerard, Jean-Pierre Bourguignon & Gary L. Westbrook. (2011) Early Developmental Actions of Endocrine Disruptors on the Hypothalamus, Hippocampus, and Cerebral Cortex. Journal of Toxicology and Environmental Health, Part B 14:5-7, pages 328-345.
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DonaldT. Wigle, TyeE. Arbuckle, MichelleC. Turner, Annie Bérubé, Qiuying Yang, Shiliang Liu & Daniel Krewski. (2008) Epidemiologic Evidence of Relationships Between Reproductive and Child Health Outcomes and Environmental Chemical Contaminants. Journal of Toxicology and Environmental Health, Part B 11:5-6, pages 373-517.
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WarrenG. Foster, MichaelS. Neal, Myoung-Soek Han & MiguelM. Dominguez. (2008) Environmental Contaminants and Human Infertility: Hypothesis or Cause for Concern?. Journal of Toxicology and Environmental Health, Part B 11:3-4, pages 162-176.
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Annie Bérubé. (2007) Toward an Economic Analysis of the Environmental Burden of Disease Among Canadian Children. Journal of Toxicology and Environmental Health, Part B 10:1-2, pages 131-142.
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Articles from other publishers (52)

Shiqi Lin, Jiajia Li, Xiaojin Yan, Lijun Pei & Xuejun Shang. (2023) Maternal pesticide exposure and risk of preterm birth: A systematic review and meta-analysis. Environment International 178, pages 108043.
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Alejandra A. Covarrubias, Erwin De la Fuente-Ortega, Gabriela Rossi, Ennio Cocca, Mosè Rossi, Gianna Palmieri & Floria C. Pancetti. (2022) Differential Distribution and Activity Profile of Acylpeptide Hydrolase in the Rat Seminiferous Epithelium. Biomedicines 10:7, pages 1591.
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Azhar u dinMr.Mr.. (2022) HEALTH IMPACTS IN THE LIGHT OF PESTICIDE CONSUMPTION: A REVIEW. Towards Excellence, pages 922-932.
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. (2022) Poultry feed contamination and its potential hazards on human health. Biomedical Letters 8:1, pages 70-81.
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Abhijit Hazra, Amita Mondal, Suparna Paul, Sourav Bej, Udayan Mondal, Somrita Nag & Priyabrata Banerjee. 2022. Emerging Contaminants in the Environment. Emerging Contaminants in the Environment 407 464 .
Ela Rydz, Kristian Larsen & Cheryl E Peters. (2021) Estimating Exposure to Three Commonly Used, Potentially Carcinogenic Pesticides (Chlorolathonil, 2,4-D, and Glyphosate) Among Agricultural Workers in Canada. Annals of Work Exposures and Health 65:4, pages 377-389.
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Yonit A. Addissie, Paul Kruszka, Angela Troia, Zoë C. Wong, Joshua L. Everson, Beth A. Kozel, Robert J. Lipinski, Kristen M. C. Malecki & Maximilian Muenke. (2020) Prenatal exposure to pesticides and risk for holoprosencephaly: a case-control study. Environmental Health 19:1.
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Ionela-Catalina Vasilachi, Larsia Tapciuc, Gina-Mihaela Finaru Chelaru, Dana-Mihaela Asiminicesei, Mihaela Rsca, Petronela Cozma, Elena-Diana Comanta-Ungureanu, Camelia Smaranda, Raluca-Maria Hlihor, Daniela-Ionela Fertu & Maria Gavrilescu. (2020) Pesticides in the Environment and Harmonized Risk Indicators. Pesticides in the Environment and Harmonized Risk Indicators.
Duvan Sebastián Valbuena, María Paula Meléndez-Flórez, Victoria Eugenia Villegas, Magda Carolina Sánchez & Milena Rondón-Lagos. (2020) Daño celular y genético como determinantes de la toxicidad de los plaguicidas. Ciencia en Desarrollo 11:2, pages 25-42.
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Jolene Kokroko, Katherine Kogut, Kim Harley & Brenda Eskenazi. (2020) Prenatal β-Hexachlorocyclohexane (β-HCH) Exposure and 7-Year Child IQ in the CHAMACOS Birth Cohort. Neurotoxicity Research 37:3, pages 553-563.
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Shameer Khan Bin Sulaiman, Yusoff Ibrahim & Mohammad Saffree Jeffree. (2019) Evaluating the perception of farmers towards pesticides and the health effect of pesticides: A cross-sectional study in the oil palm plantations of Papar, Malaysia. Interdisciplinary Toxicology 12:1, pages 15-25.
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Dong-Jun Fu, Ping Li, Jian Song, Sai-Yang Zhang & Han-Zhong Xie. (2019) Mechanisms of synergistic neurotoxicity induced by two high risk pesticide residues – Chlorpyrifos and Carbofuran via oxidative stress. Toxicology in Vitro 54, pages 338-344.
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Wei-Chun Chou, Wei-Ren Tsai, Hsiu-Hui Chang, Shui-Yuan Lu, King-Fu Lin & Pinpin Lin. (2019) Prioritization of pesticides in crops with a semi-quantitative risk ranking method for Taiwan postmarket monitoring program. Journal of Food and Drug Analysis 27:1, pages 347-354.
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S. Parvez, R. R. Gerona, C. Proctor, M. Friesen, J. L. Ashby, J. L. Reiter, Z. Lui & P. D. Winchester. (2018) Glyphosate exposure in pregnancy and shortened gestational length: a prospective Indiana birth cohort study. Environmental Health 17:1.
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Chien-Che Hung, Feng-Jung Huang, Ya-Qing Yang, Chia-Jung Hsieh, Chun-Chieh Tseng & Lih-Ming Yiin. (2018) Pesticides in indoor and outdoor residential dust: a pilot study in a rural county of Taiwan. Environmental Science and Pollution Research 25:23, pages 23349-23356.
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Charikleia Kalliora, Charalampos Mamoulakis, Eleni Vasilopoulos, George A. Stamatiades, Lydia Kalafati, Roza Barouni, Triantafyllia Karakousi, Mohammad Abdollahi & Aristidis Tsatsakis. (2018) Association of pesticide exposure with human congenital abnormalities. Toxicology and Applied Pharmacology 346, pages 58-75.
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E. Corsini, C. Colosio & JB. Barnett. 2018. Comprehensive Toxicology. Comprehensive Toxicology 761 773 .
Charlene C. Nielsen, Carl G. Amrhein & Alvaro R. Osornio-Vargas. (2017) Mapping outdoor habitat and abnormally small newborns to develop an ambient health hazard index. International Journal of Health Geographics 16:1.
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Hie Ling Wong, David G. Garthwaite, Carmel T. Ramwell & Colin D. Brown. (2017) How does exposure to pesticides vary in space and time for residents living near to treated orchards?. Environmental Science and Pollution Research 24:34, pages 26444-26461.
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Jane A. Hoppin & Catherine E. LePrevost. 2017. Environmental Pest Management. Environmental Pest Management 249 273 .
Élida Campos & Carmen Freire. (2016) Exposure to non-persistent pesticides and thyroid function: A systematic review of epidemiological evidence. International Journal of Hygiene and Environmental Health 219:6, pages 481-497.
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Daniele Focosi, Fabrizio Maggi & Mauro Pistello. (2016) Zika Virus: Implications for Public Health. Clinical Infectious Diseases 63:2, pages 227-233.
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Zahra Khoshnood. (2016) Using Biomarkers in Ecotoxicology: What and Why?. Focus on Sciences 2:2, pages 1-10.
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Alison J. Falck, Sandra Mooney, Shiv S. Kapoor, Kimberly M.R. White, Cynthia Bearer & Dina El Metwally. (2015) Developmental Exposure to Environmental Toxicants. Pediatric Clinics of North America 62:5, pages 1173-1197.
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Guodong Ding, Chang Cui, Limei Chen, Yu Gao, Yijun Zhou, Rong Shi & Ying Tian. (2014) Prenatal exposure to pyrethroid insecticides and birth outcomes in Rural Northern China. Journal of Exposure Science & Environmental Epidemiology 25:3, pages 264-270.
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Michael Goodman, Jack S. Mandel, John M. DeSesso & Anthony R. Scialli. (2014) Atrazine and Pregnancy Outcomes: A Systematic Review of Epidemiologic Evidence. Birth Defects Research Part B: Developmental and Reproductive Toxicology 101:3, pages 215-236.
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Ru Qiong Qin, Ling Yun Mo, Hong Hu Zeng, Li Tang Qin & Yan Peng Liang. (2014) Progress on OCPs and Chronic Disease. Applied Mechanics and Materials 535, pages 383-387.
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Emilien L. Jamin, Nathalie Bonvallot, Marie Tremblay-Franco, Jean-Pierre Cravedi, Cécile Chevrier, Sylvaine Cordier & Laurent Debrauwer. (2013) Untargeted profiling of pesticide metabolites by LC–HRMS: an exposomics tool for human exposure evaluation. Analytical and Bioanalytical Chemistry 406:4, pages 1149-1161.
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Mikel Basterrechea, Aitana Lertxundi, Carmen Iñiguez, Michelle Mendez, Mario Murcia, Imanol Mozo, Fernando Goñi, Joan Grimalt, Marieta Fernández & Mònica Guxens. (2014) Prenatal exposure to hexachlorobenzene (HCB) and reproductive effects in a multicentre birth cohort in Spain. Science of The Total Environment 466-467, pages 770-776.
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Guodong Ding & Ying Tian. (2013) Organophosphate pesticide exposure and child health in China. Environmental Science and Pollution Research 21:1, pages 759-760.
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S P S GHUMAN, U RATNAKARAN, J S BEDI & J P S GILL. (2013) Impact of pesticide residues on fertility of dairy animals: A review. The Indian Journal of Animal Sciences 83:12.
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R. Slama & S. Cordier. (2013) Impact des facteurs environnementaux physiques et chimiques sur le déroulement et les issues de grossesse. Journal de Gynécologie Obstétrique et Biologie de la Reproduction 42:5, pages 413-444.
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Susan R. Reutman & Juliana W. Meadows. 2013. Effects of Persistent and Bioactive Organic Pollutants on Human Health. Effects of Persistent and Bioactive Organic Pollutants on Human Health 237 314 .
A. Blanc-Lapierre, G. Bouvier, A. Gruber, K. Leffondre, P. Lebailly, C. Fabrigoule & I. Baldi. (2013) Cognitive Disorders and Occupational Exposure to Organophosphates: Results From the PHYTONER Study. American Journal of Epidemiology 177:10, pages 1086-1096.
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Sara Mostafalou & Mohammad Abdollahi. (2013) Pesticides and human chronic diseases: Evidences, mechanisms, and perspectives. Toxicology and Applied Pharmacology 268:2, pages 157-177.
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James R. Roberts, Catherine J. Karr, Jerome A. Paulson, Alice C. Brock-Utne, Heather L. Brumberg, Carla C. Campbell, Bruce P. Lanphear, Kevin C. Osterhoudt, Megan T. Sandel, Leonardo Trasande & Robert O. Wright. (2012) Pesticide Exposure in Children. Pediatrics 130:6, pages e1765-e1788.
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Isabelle Baldi, Pierre Lebailly, Virginie Rondeau, Valérie Bouchart, Audrey Blanc-Lapierre, Ghislaine Bouvier, Mireille Canal-Raffin & Alain Garrigou. (2012) Levels and determinants of pesticide exposure in operators involved in treatment of vineyards: results of the PESTEXPO Study. Journal of Exposure Science & Environmental Epidemiology 22:6, pages 593-600.
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A. Blanc-Lapierre, G. Bouvier, A. Garrigou, M. Canal-Raffin, C. Raherison, P. Brochard & I. Baldi. (2012) Effets chroniques des pesticides sur le système nerveux central : état des connaissances épidémiologiques. Revue d'Épidémiologie et de Santé Publique 60:5, pages 389-400.
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Leslie London, Cheryl Beseler, Maryse F. Bouchard, David C. Bellinger, Claudio Colosio, Philippe Grandjean, Raul Harari, Tahira Kootbodien, Hans Kromhout, Francesca Little, Tim Meijster, Angelo Moretto, Diane S. Rohlman & Lorann Stallones. (2012) Neurobehavioral and neurodevelopmental effects of pesticide exposures. NeuroToxicology 33:4, pages 887-896.
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Francielle Tatiane Mathias, Renata Marino Romano, Hanan Kaled Sleiman, Claudio Alvarenga de Oliveira & Marco Aurelio Romano. (2012) Herbicide Metolachlor Causes Changes in Reproductive Endocrinology of Male Wistar Rats. ISRN Toxicology 2012, pages 1-7.
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Claudia A. Snijder, Nel Roeleveld, Egbert te Velde, Eric A.P. Steegers, Hein Raat, Albert Hofman, Vincent W.V. Jaddoe & Alex Burdorf. (2012) Occupational exposure to chemicals and fetal growth: the Generation R Study. Human Reproduction 27:3, pages 910-920.
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Mauro Giustini, Mattia Autullo, Mauro Mennuni, Gerardo Palazzo & Antonia Mallardi. (2012) Polymer-photosynthetic protein multilayer architectures for herbicide optical detection. Sensors and Actuators B: Chemical 163:1, pages 69-75.
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Alexandre Nougadère, Jean-Cédric Reninger, Jean-Luc Volatier & Jean-Charles Leblanc. (2011) Chronic dietary risk characterization for pesticide residues: A ranking and scoring method integrating agricultural uses and food contamination data. Food and Chemical Toxicology 49:7, pages 1484-1510.
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Adeleh Shirangi, Mark Nieuwenhuijsen, Danielle Vienneau & C.D'Arcy J. Holman. (2010) Living near agricultural pesticide applications and the risk of adverse reproductive outcomes: a review of the literature. Paediatric and Perinatal Epidemiology 25:2, pages 172-191.
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Yan Yan Qin, Clement K. M. Leung, C. K. Lin, Anna O. W. Leung, Hong Sheng Wang, John P. Giesy & Ming H. Wong. (2011) Halogenated POPs and PAHs in Blood Plasma of Hong Kong Residents. Environmental Science & Technology 45:4, pages 1630-1637.
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Frank Barile. 2010. Clinical Toxicology. Clinical Toxicology 363 375 .
Zhong-Cheng Luo, Jian-Meng Liu & William D. Fraser. (2010) Large prospective birth cohort studies on environmental contaminants and child health – Goals, challenges, limitations and needs. Medical Hypotheses 74:2, pages 318-324.
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Rémy Slama & Sylvaine Cordier. 2010. Environmental Impacts on Reproductive Health and Fertility. Environmental Impacts on Reproductive Health and Fertility.
Kathleen M. Brundage & John B. Barnett. 2010. Hayes' Handbook of Pesticide Toxicology. Hayes' Handbook of Pesticide Toxicology 483 497 .
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