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Original Articles

Pharmaceuticals as Neuroendocrine Disruptors: Lessons Learned from Fish on Prozac

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Pages 387-412 | Published online: 26 Jul 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

Ifenna Ilechukwu, Chioma Joy Okonkwo, Tolulope Abisola Olusina, Jarvis Abel Mpock & Chibuamam Ilechukwu. (2023) Occurrence and risk assessment of selected pharmaceuticals in water and sediments of Usuma Dam, Abuja, Nigeria. International Journal of Environmental Analytical Chemistry 103:16, pages 4398-4410.
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Amanda Carolina Cole Varela, Suelen Mendonça Soares, Milena Fortuna, Vitória Cadore Costa, Ísis Piasson Barletto, Mateus Timbola Mozatto, Lisiane Siqueira, Heloísa Helena de Alcantara Barcellos, Rodrigo Egydio Barreto & Leonardo José Gil Barcellos. (2023) A single exposure to sub-lethal concentrations of a glyphosate-based herbicide or fluoxetine-based agent on growth performance in Nile tilapia. Journal of Toxicology and Environmental Health, Part A 86:15, pages 534-542.
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Zeyana Al-Ghafri, Aziz A. Al-Habsi & Michael J. Barry. (2023) Atorvastatin and gemfibrozil alter zebrafish behavior. Marine and Freshwater Behaviour and Physiology 56:3-4, pages 73-89.
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Susana Barros, Ana M. Coimbra, Nélson Alves, Marlene Pinheiro, José Benito Quintana, Miguel M. Santos & Teresa Neuparth. (2020) Chronic exposure to environmentally relevant levels of simvastatin disrupts zebrafish brain gene signaling involved in energy metabolism. Journal of Toxicology and Environmental Health, Part A 83:3, pages 113-125.
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Erinn K. Richmond, Emma J. Rosi, Alexander J. Reisinger, Brittany R. Hanrahan, Ross M. Thompson & Michael R. Grace. (2019) Influences of the antidepressant fluoxetine on stream ecosystem function and aquatic insect emergence at environmentally realistic concentrations. Journal of Freshwater Ecology 34:1, pages 513-531.
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Adrieli Sachett, Fernanda Bevilaqua, Rafael Chitolina, Cristiane Garbinato, Henrique Gasparetto, Jacir Dal Magro, Greicy M Conterato & Anna M Siebel. (2018) Ractopamine hydrochloride induces behavioral alterations and oxidative status imbalance in zebrafish. Journal of Toxicology and Environmental Health, Part A 81:7, pages 194-201.
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Emily E. Burns, Laura J. Carter, Jason Snape, Jane Thomas-Oates & Alistair B.A. Boxall. (2018) Application of prioritization approaches to optimize environmental monitoring and testing of pharmaceuticals. Journal of Toxicology and Environmental Health, Part B 21:3, pages 115-141.
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Tomas Brodin, Johanna Nordling, Annelie Lagesson, Jonatan Klaminder, Gustav Hellström, Bent Christensen & Jerker Fick. (2017) Environmental relevant levels of a benzodiazepine (oxazepam) alters important behavioral traits in a common planktivorous fish, (Rutilus rutilus). Journal of Toxicology and Environmental Health, Part A 80:16-18, pages 963-970.
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Cheryl S. Rosenfeld, Nancy D. Denslow, Edward F. Orlando, Juan Manuel Gutierrez-Villagomez & Vance L Trudeau. (2017) Neuroendocrine disruption of organizational and activational hormone programming in poikilothermic vertebrates. Journal of Toxicology and Environmental Health, Part B 20:5, pages 276-304.
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Steven D. Melvin, Mark C. Cameron & Chantal M. Lanctôt. (2014) Individual and Mixture Toxicity of Pharmaceuticals Naproxen, Carbamazepine, and Sulfamethoxazole to Australian Striped Marsh Frog Tadpoles (Limnodynastes peronii). Journal of Toxicology and Environmental Health, Part A 77:6, pages 337-345.
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Yann Le Page, Mélanie Vosges, Arianna Servili, François Brion & Olivier Kah. (2011) Neuroendocrine Effects of Endocrine Disruptors in Teleost Fish. Journal of Toxicology and Environmental Health, Part B 14:5-7, pages 370-386.
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Andrew Waye & Vance L. Trudeau. (2011) Neuroendocrine Disruption: More Than Hormones are Upset. Journal of Toxicology and Environmental Health, Part B 14:5-7, pages 270-291.
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Teresa L. Dzieweczynski, Brennah A. Campbell & Jessica L. Kane. (2016) Dose-dependent fluoxetine effects on boldness in male Siamese fighting fish. Journal of Experimental Biology 219:6, pages 797-804.
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Marco Pelli & Victoria P. Connaughton. (2015) Chronic exposure to environmentally-relevant concentrations of fluoxetine (Prozac) decreases survival, increases abnormal behaviors, and delays predator escape responses in guppies. Chemosphere 139, pages 202-209.
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Marion Sebire, Jessica Elphinstone Davis, Robert Hatfield, Svante Winberg & Ioanna Katsiadaki. (2015) Prozac affects stickleback nest quality without altering androgen, spiggin or aggression levels during a 21-day breeding test. Aquatic Toxicology 168, pages 78-89.
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