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Relevance of mouse lung tumors to human risk assessment

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Tomoya Yamada, Brian G. Lake & Samuel M. Cohen. (2022) Evaluation of the human hazard of the liver and lung tumors in mice treated with permethrin based on mode of action. Critical Reviews in Toxicology 52:1, pages 1-31.
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Sun Woo Jin, Jong Seung Im, Jae Hyeon Park, Hyung Gyun Kim, Gi Ho Lee, Se Jong Kim, Seung Jun Kwack, Kyu-Bong Kim, Kyu Hyuck Chung, Byung Mu Lee, Sam Kacew, Hye Gwang Jeong & Hyung Sik Kim. (2021) Effects of tobacco compound 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) on the expression of epigenetically regulated genes in lung carcinogenesis. Journal of Toxicology and Environmental Health, Part A 84:24, pages 1004-1019.
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M. Noruzi & M. Sharifzadeh. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 675 680 .
Lyle D. Burgoon, Christopher J. Borgert, Claudio Fuentes & James E. Klaunig. (2023) Kinetically-derived maximal dose (KMD) indicates lack of human carcinogenicity of ethylbenzene. Archives of Toxicology.
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S.P. Felter, D.J. Ponting, A.M. Mudd, R. Thomas & A.A.F. Oliveira. (2023) Maximizing use of existing carcinogenicity data to support acceptable intake levels for mutagenic impurities in pharmaceuticals: Learnings from N-nitrosamine case studies. Regulatory Toxicology and Pharmacology 143, pages 105459.
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Christian Strupp, Marco Corvaro, Samuel M. Cohen, J. Christopher Corton, Kumiko Ogawa, Lysiane Richert & Miriam N. Jacobs. (2023) Increased Cell Proliferation as a Key Event in Chemical Carcinogenesis: Application in an Integrated Approach for the Testing and Assessment of Non-Genotoxic Carcinogenesis. International Journal of Molecular Sciences 24:17, pages 13246.
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Joanna Klapacz & Claire Doskey. 2003. Patty's Toxicology. Patty's Toxicology 1 59 .
Susan J. Borghoff, Sarah S. Cohen, Xiaohui Jiang, Isabel A. Lea, William D. Klaren, Grace A. Chappell, Janice K. Britt, Brianna N. Rivera, Neepa Y. Choski & Daniele S. Wikoff. (2023) Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame. Food and Chemical Toxicology 172, pages 113549.
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Marjory Moreau, Jeff Fisher, Melvin E. Andersen, Asayah Barnwell, Sage Corzine, Aarati Ranade, Patrick D. McMullen & Scott D. Slattery. (2022) NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1,3-dichloropropene. Toxicology 481, pages 153340.
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Keiko Ogata, Yang Liu, Ayako Ohara, Kensuke Kawamoto, Miwa Kondo, Kumiko Kobayashi, Takako Fukuda, Hiroyuki Asano, Sachiko Kitamoto, Brian G Lake, Samuel M Cohen & Tomoya Yamada. (2021) Club Cells Are the Primary Target for Permethrin-Induced Mouse Lung Tumor Formation. Toxicological Sciences 184:1, pages 15-32.
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Kelly L Harris, Karen L McKim, Meagan B Myers, Binsheng Gong, Joshua Xu & Barbara L Parsons. (2021) Assessment of Clonal Expansion Using CarcSeq Measurement of Lung Cancer Driver Mutations and Correlation With Mouse Strain- and Sex-Related Incidence of Spontaneous Lung Neoplasia. Toxicological Sciences 184:1, pages 1-14.
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Susan J. Borghoff, Seneca E. Fitch, Michael B. Black, Patrick D. McMullen, Melvin E. Andersen & Grace A. Chappell. (2021) A systematic approach to evaluate plausible modes of actions for mouse lung tumors in mice exposed to 4-methylimidozole. Regulatory Toxicology and Pharmacology 124, pages 104977.
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Carr J. Smith, Thomas A. Perfetti, A. Wallace Hayes, Sir Colin Berry, James E. Trosko, Judy A. King, Jay I. Goodman, C. Glenn Begley & Anthony Dayan. (2021) Categorizing the characteristics of human carcinogens: a need for specificity. Archives of Toxicology 95:8, pages 2883-2889.
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Wolfgang Dekant, Paul Jean & Josje Arts. (2021) Evaluation of the carcinogenicity of dichloromethane in rats, mice, hamsters and humans. Regulatory Toxicology and Pharmacology 120, pages 104858.
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Tomoya Yamada. (2021) Application of humanized mice to toxicology studies: Evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR). Journal of Toxicologic Pathology 34:4, pages 283-297.
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B. Bhaskar Gollapudi, Amy L. Williams & James S. Bus. (2021) A review of the genotoxicity of the industrial chemical cumene. Mutation Research/Reviews in Mutation Research 787, pages 108364.
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David Brusick, Marilyn J. Aardema, William T. Allaben, David J. Kirkland, Gary Williams, G. Craig Llewellyn, Julia M. Parker & Marisa O. Rihner. (2020) A weight of evidence assessment of the genotoxic potential of 4-methylimidazole as a possible mode of action for the formation of lung tumors in exposed mice. Food and Chemical Toxicology 145, pages 111652.
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Carr J Smith, Thomas A Perfetti & Richard G Morford. (2020) Use of 1-bromopropane (N-propyl bromide) in dry cleaning is rare and rapidly declining toward obsolescence. Toxicology Research and Application 4, pages 239784732096696.
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