Citations (69)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (2)
Syarief Thaufik Hidayat, Inu Mulyantoro, Suhartono Damas & Raymond R Tjandrawinata. (2023) The Effect and Safety Assessment of Metformin and DLBS3233 (A Bioactive Fraction of Lagerstroemia speciosa and Cinnamomum burmannii) on Improving Metabolic Parameters in Women with Polycystic Ovary Syndrome. International Journal of Women's Health 15, pages 971-985.
Read now
Read now
Yifan Zhou & Baojun Xu. (2022) New insights into anti-diabetes effects and molecular mechanisms of dietary saponins. Critical Reviews in Food Science and Nutrition 0:0, pages 1-26.
Read now
Read now
Articles from other publishers (67)
Xinxiu Ren, Qinfeng Guo, Hui Jiang, Xiao Han, Xiaoshi He, Haodong Liu, Zhilong Xiu & Yuesheng Dong. (2023) Combinational application of the natural products 1-deoxynojirimycin and morin ameliorates insulin resistance and lipid accumulation in prediabetic mice. Phytomedicine 121, pages 155106.
Crossref
Crossref
Piaojian Yu, Wei Wang, Wanrong Guo, Lidan Cheng, Zhiping Wan, Yanglei Cheng, Yunfeng Shen & Fen Xu. (2023) Pioglitazone-Enhanced Brown Fat Whitening Contributes to Weight Gain
in Diet-Induced Obese Mice. Experimental and Clinical Endocrinology & Diabetes 131:11, pages 595-604.
Crossref
Crossref
Xianfeng Liu, Xinmei Xu, Tao Zhang, Lei Xu, Honglin Tao, Yue Liu, Yi Zhang & Xianli Meng. (2023) Fatty acid metabolism disorders and potential therapeutic traditional Chinese medicines in cardiovascular diseases. Phytotherapy Research 37:11, pages 4976-4998.
Crossref
Crossref
Yufan Chao, Na Li, Shili Xiong, Guangbo Zhang, Songyan Gao & Xin Dong. (2023) Lipidomics based on liquid chromatography‐high resolution mass spectrometry reveals the protective role of peroxisome proliferator‐activated receptor alpha on kidney stone formation in mice treated with glyoxylate. Journal of Separation Science.
Crossref
Crossref
Elza Fonseca, María Vázquez, Laura Rodriguez-Lorenzo, Natalia Mallo, Ivone Pinheiro, Maria Lígia Sousa, Santiago Cabaleiro, Monica Quarato, Miguel Spuch-Calvar, Miguel A. Correa-Duarte, Juan José López-Mayán, Mick Mackey, Antonio Moreda, Vítor Vasconcelos, Begoña Espiña, Alexandre Campos & Mário Jorge Araújo. (2023) Getting fat and stressed: Effects of dietary intake of titanium dioxide nanoparticles in the liver of turbot Scophthalmus maximus. Journal of Hazardous Materials 458, pages 131915.
Crossref
Crossref
Jingqian Su, Yingsheng Luo, Shan Hu, Lu Tang & Songying Ouyang. (2023) Advances in Research on Type 2 Diabetes Mellitus Targets and Therapeutic Agents. International Journal of Molecular Sciences 24:17, pages 13381.
Crossref
Crossref
Jinmiao Tian, Lichao Zhang, Xiaoqin La, Xiaxia Fan, Aiping Li, Changxin Wu, Yuxuan An, Shuning Yan, Xiushan Dong, Haitao Wu & Zhuoyu Li. (2023) Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism. Cellular Signalling 108, pages 110719.
Crossref
Crossref
Sayuri Takahashi, Ichiro Takada, Kenichi Hashimoto, Atsushi Yokoyama, Tohru Nakagawa, Makoto Makishima & Haruki Kume. (2023) ESS2 controls prostate cancer progression through recruitment of chromodomain helicase DNA binding protein 1. Scientific Reports 13:1.
Crossref
Crossref
Bin Zhai, Hongtai Li, Shuaihao Li, Jinxing Gu, Hongyuan Zhang, Yanhua Zhang, Hong Li, Yadong Tian, Guoxi Li & Yongcai Wang. (2023) Transcriptome analysis reveals FABP5 as a key player in the development of chicken abdominal fat, regulated by miR-122-5p targeting. BMC Genomics 24:1.
Crossref
Crossref
Huijing Lv, Shuai Jia, Yanan Sun, Meng Pang, E. Lv, Xiangling Li, Qinghui Meng & Yanqiang Wang. (2023) Docosahexaenoic acid promotes M2 microglia phenotype via activating PPARγ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury. Brain Research Bulletin 199, pages 110660.
Crossref
Crossref
Yuan-Ye Qiu, Jing Zhang, Fan-Yi Zeng & Yi Zhun Zhu. (2023) Roles of the peroxisome proliferator-activated receptors (PPARs) in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Pharmacological Research 192, pages 106786.
Crossref
Crossref
Dinara Amankulova, Gulzat Berganayeva, Bates Kudaibergenova, Dinara Zhetpisbay, Ayshagul Sharipova & Moldyr Dyusebaeva. (2023) Recent Advances in the Synthesis and Applications of m-Aryloxy Phenols. Molecules 28:6, pages 2657.
Crossref
Crossref
Karol Mierzejewski, Aleksandra Kurzyńska, Zuzanna Gerwel, Monika Golubska, Robert Stryiński & Iwona Bogacka. (2023) PPARβ/δ Ligands Regulate Oxidative Status and Inflammatory Response in Inflamed Corpus Luteum—An In Vitro Study. International Journal of Molecular Sciences 24:5, pages 4993.
Crossref
Crossref
Bianca Seminotti, Mateus Grings, Nícolas Manzke Glänzel, Jerry Vockley & Guilhian Leipnitz. (2023) Peroxisome proliferator-activated receptor (PPAR) agonists as a potential therapy for inherited metabolic disorders. Biochemical Pharmacology 209, pages 115433.
Crossref
Crossref
Qingping Shi, Feihong Chen, Yuanyi Feng, Yangxi Zheng, Ximei Zhi & Wen Wu. (2023) Exogenous Hydrogen Sulfide Mitigates Oxidative Stress and Mitochondrial Damages Induced by Polystyrene Microplastics in Osteoblastic Cells of Mice. Disease Markers 2023, pages 1-8.
Crossref
Crossref
Qingqing Yao, Jiahuan Chen, Xuechao Li, Wen Yang, Jianan Ning, Qi Liang & Qian Li. (2023) Site-selective covalent immobilization of PPARγ using a label-free strategy for chromatographic study. Microchemical Journal 185, pages 108278.
Crossref
Crossref
Karen R. Gaar-Humphreys, Alyssa van den Brink, Mark Wekking, Folkert W. Asselbergs, Frank G. van Steenbeek, Magdalena Harakalova & Jiayi Pei. (2023) Targeting lipid metabolism as a new therapeutic strategy for inherited cardiomyopathies. Frontiers in Cardiovascular Medicine 10.
Crossref
Crossref
Sergio Ammendola & Anna Scotto d’Abusco. (2022) Nutraceuticals and the Network of Obesity Modulators. Nutrients 14:23, pages 5099.
Crossref
Crossref
Yumeng Miao, Changliu Zhang, Ling Yang, Xi Zeng, Yuxiao Hu, Xinru Xue, Yue Dai & Zhifeng Wei. (2022) The activation of PPARγ enhances Treg responses through up-regulating CD36/CPT1-mediated fatty acid oxidation and subsequent N-glycan branching of TβRII/IL-2Rα. Cell Communication and Signaling 20:1.
Crossref
Crossref
Manimegalai Sengani, Bavithra V, Manosi Banerjee, Abbas Alam Choudhury, Shreya Chakraborty, Kanagavalli Ramasubbu, Devi Rajeswari V, Sami Al Obaid, Sulaiman Ali Alharbi, Baskaran Subramani & Kathirvel Brindhadevi. (2022) Evaluation of the anti-diabetic effect of biogenic silver nanoparticles and intervention in PPARγ gene regulation. Environmental Research 215, pages 114408.
Crossref
Crossref
Biao Huang, Lu An, Wenxing Su, Tao Yan, Haifang Zhang & Dao-Jiang Yu. (2022) Exploring the alterations and function of skin microbiome mediated by ionizing radiation injury. Frontiers in Cellular and Infection Microbiology 12.
Crossref
Crossref
Solveig A. Krapf, Jenny Lund, Awais Ur Rehman Saqib, Hege G. Bakke, Arild C. Rustan, G. Hege Thoresen & Eili T. Kase. (2022) Pancreatic Cancer Cell-Conditioned, Human-Derived Primary Myotubes Display Increased Leucine Turnover, Increased Lipid Accumulation, and Reduced Glucose Uptake. Metabolites 12:11, pages 1095.
Crossref
Crossref
Sharma Arvind Virendra, Ankur Kumar, Pooja A. Chawla & Narsimha Mamidi. (2022) Development of Heterocyclic PPAR Ligands for Potential Therapeutic Applications. Pharmaceutics 14:10, pages 2139.
Crossref
Crossref
Caijie Gao, Xu Zhao & Jianrong Fan. (2022) Computational design and experimental confirmation of conformationally constrained peptides to compete with coactivators for pediatric PPARα by minimizing indirect readout effect. Journal of Bioinformatics and Computational Biology 20:05.
Crossref
Crossref
Yonggang Sha, Jian Wu, Barry Paul, Yue Zhao, Parker Mathews, Zhiguo Li, John Norris, Endi Wang, Donald P. McDonnell & Yubin Kang. (2022) PPAR agonists attenuate lenalidomide's anti-myeloma activity in vitro and in vivo. Cancer Letters 545, pages 215832.
Crossref
Crossref
Fangyuan Chen, Lei Ma, Guihui Cai, Junyuan Tang, Yi Wang, Qingmei Liu, Xiawen Liu, Ning Hou, Zhi Zhou & Wei Yi. (2022) Identification of a novel PPARγ modulator with good anti-diabetic therapeutic index via structure-based screening, optimization and biological validation. Biomedicine & Pharmacotherapy 154, pages 113653.
Crossref
Crossref
Ankur Kumar, Simranpreet K. Wahan, Sharma Arvind Virendra & Pooja A. Chawla. (2022) Recent Advances on the Role of Nitrogen‐Based Heterocyclic Scaffolds in Targeting HIV through Reverse Transcriptase Inhibition. ChemistrySelect 7:36.
Crossref
Crossref
Qiang Yin, Annoor Awadasseid, Yongnan Zhou, Ming Wang, Xuqiong Xiong, Yanling Wu & Wen Zhang. (2022) 4,5-diazafenylfluorene-rhodanine conjugates promote anoikis in A375 cells via inhibiting PPAR-γ expression. Medicinal Chemistry Research 31:9, pages 1476-1487.
Crossref
Crossref
Yajun Chen, Yiping He, Xinyi Wu, Xuesong Xu, Junhua Gong, Yong Chen & Jianping Gong. (2022) Rubicon promotes the M2 polarization of Kupffer cells via LC3-associated phagocytosis-mediated clearance to improve liver transplantation. Cellular Immunology 378, pages 104556.
Crossref
Crossref
Yichen Tong, Wentao Zhu, Tianzhi Wen, Zere Mukhamejanova, Fang Xu, Qi Xiang & Jiyan Pang. (2022) Xyloketal B Reverses Nutritional Hepatic Steatosis, Steatohepatitis, and Liver Fibrosis through Activation of the PPARα/PGC1α Signaling Pathway. Journal of Natural Products 85:7, pages 1738-1750.
Crossref
Crossref
Jian Wu, Min Zhang & Allison Faircloth. (2022) Role of PPAR Receptor and Ligands in the Pathogenesis and Therapy of Hematologic Malignancies. Hemato 3:3, pages 422-433.
Crossref
Crossref
Yifeng He, Haijian Li, Yunhe He, Caijie Lu, Peiyi Zhu, Mingyi Li, Juan Duan & Zhixin Fang. (2022) Troglitazone inhibits hepatic oval cell proliferation by inducing cell cycle arrest through Hippo/YAP pathway regulation. Digestive and Liver Disease 54:6, pages 791-799.
Crossref
Crossref
Mami Yoshizawa, Tomomi Aoyama, Toshimasa Itoh & Hiroyuki Miyachi. (2022) Arylalkynyl amide-type peroxisome proliferator-activated receptor γ (PPARγ)-selective antagonists covalently bind to the PPARγ ligand binding domain with a unique binding mode. Bioorganic & Medicinal Chemistry Letters 64, pages 128676.
Crossref
Crossref
Si-Nan Lin, Ren Mao, Chenchen Qian, Dominik Bettenworth, Jie Wang, Jiannan Li, David H. Bruining, Vipul Jairath, Brian G. Feagan, Min-Hu Chen & Florian Rieder. (2022) Development of antifibrotic therapy for stricturing Crohn’s disease: lessons from randomized trials in other fibrotic diseases. Physiological Reviews 102:2, pages 605-652.
Crossref
Crossref
Gajanan D. Katkar, Ibrahim M. Sayed, Mahitha Shree Anandachar, Vanessa Castillo, Eleadah Vidales, Daniel Toobian, Fatima Usmani, Joseph R. Sawires, Geoffray Leriche, Jerry Yang, William J. Sandborn, Soumita Das, Debashis Sahoo & Pradipta Ghosh. (2022) Artificial intelligence-rationalized balanced PPARα/γ dual agonism resets dysregulated macrophage processes in inflammatory bowel disease. Communications Biology 5:1.
Crossref
Crossref
Karol Mierzejewski, Łukasz Paukszto, Aleksandra Kurzyńska, Zuzanna Kunicka, Jan P. Jastrzębski, Karol G. Makowczenko, Monika Golubska & Iwona Bogacka. (2022) PPARγ regulates the expression of genes involved in the DNA damage response in an inflamed endometrium. Scientific Reports 12:1.
Crossref
Crossref
Qutuba G Karwi, Kim L Ho, Simran Pherwani, Ezra B Ketema, Qiuyu Sun & Gary D Lopaschuk. (2022) Concurrent diabetes and heart failure: interplay and novel therapeutic approaches. Cardiovascular Research 118:3, pages 686-715.
Crossref
Crossref
Rossella Basilotta, Marika Lanza, Giovanna Casili, Giulia Chisari, Stefania Munao, Lorenzo Colarossi, Laura Cucinotta, Michela Campolo, Emanuela Esposito & Irene Paterniti. (2022) Potential Therapeutic Effects of PPAR Ligands in Glioblastoma. Cells 11:4, pages 621.
Crossref
Crossref
Mukut Sharma, Vikas Singh, Ram Sharma, Arnav Koul, Ellen T. McCarthy, Virginia J. Savin, Trupti Joshi & Tarak Srivastava. (2022) Glomerular Biomechanical Stress and Lipid Mediators during Cellular Changes Leading to Chronic Kidney Disease. Biomedicines 10:2, pages 407.
Crossref
Crossref
Joshua Nathanael, Putu Suardana, Yoanes Maria Vianney & Sulistyo Emantoko Dwi Putra. (2021) The role of FoxO1 and its modulation with small molecules in the development of diabetes mellitus: A review. Chemical Biology & Drug Design 99:2, pages 344-361.
Crossref
Crossref
Fang Cheng, Qiang Li, Jinglin Wang, Fang Zeng & Yu Zhang. (2022) Investigation of the Potential Mechanism of Danggui Shaoyao San for the
Treatment of Non-alcoholic Fatty Liver Disease (NAFLD) with Network
Pharmacology and Molecular Docking. Current Computer-Aided Drug Design 18:4, pages 258-270.
Crossref
Crossref
Ke Zhu, Wen Deng, Hui Deng, Xiaoqiang Liu, Gongxian Wang & Bin Fu. (2021) Identification of a Novel PPAR Signature for Predicting Prognosis, Immune Microenvironment, and Chemotherapy Response in Bladder Cancer. PPAR Research 2021, pages 1-17.
Crossref
Crossref
Sebastian Kwiatkowski, Anna Kajdy, Katarzyna Stefańska, Magdalena Bednarek-Jędrzejek, Sylwia Dzidek, Piotr Tousty, Małgorzata Sokołowska & Ewa Kwiatkowska. (2021) PPARγ—A Factor Linking Metabolically Unhealthy Obesity with Placental Pathologies. International Journal of Molecular Sciences 22:23, pages 13167.
Crossref
Crossref
Tao Wang, Jin-Fang Song, Xue-Yan Zhou, Cheng-Lin Li, Xiao-Xing Yin & Qian Lu. (2021) PPARD rs2016520 (T/C) and NOS1AP rs12742393 (A/C) polymorphisms affect therapeutic efficacy of nateglinide in Chinese patients with type 2 diabetes mellitus. BMC Medical Genomics 14:1.
Crossref
Crossref
Zheng Li, Qiang Ren, Zongtao Zhou, Zongyu Cai, Bin Wang, Jing Han & Luyong Zhang. (2021) Discovery of the first-in-class dual PPARδ/γ partial agonist for the treatment of metabolic syndrome. European Journal of Medicinal Chemistry 225, pages 113807.
Crossref
Crossref
Giuliana Muzio, Giuseppina Barrera & Stefania Pizzimenti. (2021) Peroxisome Proliferator-Activated Receptors (PPARs) and Oxidative Stress in Physiological Conditions and in Cancer. Antioxidants 10:11, pages 1734.
Crossref
Crossref
Siyu Tian, Rui Wang, Shuming Chen, Jialing He, Weili Zheng & Yong Li. (2021) Structural Basis for PPARs Activation by The Dual PPARα/γ Agonist Sanguinarine: A Unique Mode of Ligand Recognition. Molecules 26:19, pages 6012.
Crossref
Crossref
Alba Royo-García, Sarah Courtois, Beatriz Parejo-Alonso, Pilar Espiau-Romera & Patricia Sancho. (2021) Lipid droplets as metabolic determinants for stemness and chemoresistance in cancer. World Journal of Stem Cells 13:9, pages 1307-1317.
Crossref
Crossref
Maria Greabu, Silviu Constantin Badoiu, Iulia-Ioana Stanescu-Spinu, Daniela Miricescu, Alexandra Ripszky Totan, Silvia Elena Badoiu, Michel Costagliola & Viorel Jinga. (2021) Drugs Interfering with Insulin Resistance and Their Influence on the Associated Hypermetabolic State in Severe Burns: A Narrative Review. International Journal of Molecular Sciences 22:18, pages 9782.
Crossref
Crossref
Mounia Tahri-Joutey, Pierre Andreoletti, Sailesh Surapureddi, Boubker Nasser, Mustapha Cherkaoui-Malki & Norbert Latruffe. (2021) Mechanisms Mediating the Regulation of Peroxisomal Fatty Acid Beta-Oxidation by PPARα. International Journal of Molecular Sciences 22:16, pages 8969.
Crossref
Crossref
Joan Font-Díaz, Alba Jiménez-Panizo, Carme Caelles, María dM Vivanco, Paloma Pérez, Ana Aranda, Eva Estébanez-Perpiñá, Antonio Castrillo, Mercedes Ricote & Annabel F. Valledor. (2021) Nuclear receptors: Lipid and hormone sensors with essential roles in the control of cancer development. Seminars in Cancer Biology 73, pages 58-75.
Crossref
Crossref
Xin Han, YanLing Wu, Qiao Yang & Gang Cao. (2021) Peroxisome proliferator-activated receptors in the pathogenesis and therapies of liver fibrosis. Pharmacology & Therapeutics 222, pages 107791.
Crossref
Crossref
Brian J. Kress, Dong Hyun Kim, Jared R. Mayo, Jeffery T. Farris, Benjamin Heck, Jeffrey G. Sarver, Divya Andy, Jill A. Trendel, Bruce E. Heck & Paul W. Erhardt. (2021) Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis. Journal of Medicinal Chemistry 64:10, pages 6996-7032.
Crossref
Crossref
Isabella Bonilha, Francesca Zimetti, Ilaria Zanotti, Bianca Papotti & Andrei C. Sposito. (2021) Dysfunctional High-Density Lipoproteins in Type 2 Diabetes Mellitus: Molecular Mechanisms and Therapeutic Implications. Journal of Clinical Medicine 10:11, pages 2233.
Crossref
Crossref
Ana Carolina B. da C. Rodrigues, Rafaela G.A. Costa, Suellen L.R. Silva, Ingrid R.S.B. Dias, Rosane B. Dias & Daniel P. Bezerra. (2021) Cell signaling pathways as molecular targets to eliminate AML stem cells. Critical Reviews in Oncology/Hematology 160, pages 103277.
Crossref
Crossref
Katarina Kores, Janez Konc & Urban Bren. (2021) Mechanistic Insights into Side Effects of Troglitazone and Rosiglitazone Using a Novel Inverse Molecular Docking Protocol. Pharmaceutics 13:3, pages 315.
Crossref
Crossref
Ana Lago-Fernandez, Sara Zarzo-Arias, Nadine Jagerovic & Paula Morales. (2021) Relevance of Peroxisome Proliferator Activated Receptors in Multitarget Paradigm Associated with the Endocannabinoid System. International Journal of Molecular Sciences 22:3, pages 1001.
Crossref
Crossref
Márcia V. de Carvalho, Cassiano F. Gonçalves-de-Albuquerque & Adriana R. Silva. (2021) PPAR Gamma: From Definition to Molecular Targets and Therapy of Lung Diseases. International Journal of Molecular Sciences 22:2, pages 805.
Crossref
Crossref
Karol Mierzejewski, Łukasz Paukszto, Aleksandra Kurzyńska, Zuzanna Kunicka, Jan Paweł Jastrzębski & Iwona Bogacka. (2021) Transcriptome analysis of porcine endometrium after LPS-induced inflammation: effects of the PPAR-gamma ligands in vitro†. Biology of Reproduction 104:1, pages 130-143.
Crossref
Crossref
Xiaozheng Dou & Adam S. Duerfeldt. (2020) Small-Molecule Modulation of PPARs for the Treatment of Prevalent Vascular Retinal Diseases. International Journal of Molecular Sciences 21:23, pages 9251.
Crossref
Crossref
Ravikumar Manickam, Kalina Duszka & Walter Wahli. (2020) PPARs and Microbiota in Skeletal Muscle Health and Wasting. International Journal of Molecular Sciences 21:21, pages 8056.
Crossref
Crossref
Iñigo Terrén, Ane Orrantia, Joana Vitallé, Gabirel Astarloa-Pando, Olatz Zenarruzabeitia & Francisco Borrego. (2020) Modulating NK cell metabolism for cancer immunotherapy. Seminars in Hematology 57:4, pages 213-224.
Crossref
Crossref
Tara Man Kadayat, Aarajana Shrestha, Yong Hyun Jeon, Hongchan An, Jina Kim, Sung Jin Cho & Jungwook Chin. (2020) Targeting Peroxisome Proliferator-Activated Receptor Delta (PPARδ): A Medicinal Chemistry Perspective. Journal of Medicinal Chemistry 63:18, pages 10109-10134.
Crossref
Crossref
Runzhi Huang, Jiaqi Zhang, Mingxiao Li, Penghui Yan, Huabin Yin, Suna Zhai, Xiaolong Zhu, Peng Hu, Jiaxin Zhang, Ling Huang, Man Li, Zehui Sun, Tong Meng, Daoke Yang & Zongqiang Huang. (2020) The Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Pan-Cancer. PPAR Research 2020, pages 1-19.
Crossref
Crossref
Yutaro Tobita, Takeshi Arima, Yuji Nakano, Masaaki Uchiyama, Akira Shimizu & Hiroshi Takahashi. (2020) Peroxisome Proliferator-Activated Receptor Beta/Delta Agonist Suppresses Inflammation and Promotes Neovascularization. International Journal of Molecular Sciences 21:15, pages 5296.
Crossref
Crossref
А.Е. Абатуров & А.А. Никулина. (2020) Antibiotic Therapy as a Risk Factor of Obesity Development in Children. Педиатрия. Восточная Европа:2, pages 268-290.
Crossref
Crossref
Nicole Wagner & Kay-Dietrich Wagner. (2020) PPAR Beta/Delta and the Hallmarks of Cancer. Cells 9:5, pages 1133.
Crossref
Crossref