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Archives of Physiology and Biochemistry
The Journal of Metabolic Diseases
Volume 115, 2009 - Issue 3
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Original Article

Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation

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Pages 147-154 | Received 06 May 2009, Accepted 11 Jun 2009, Published online: 06 Jul 2009

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Narin Osman, Robel Getachew, Micah Burch, Graeme Lancaster, Rikang Wang, Haitau Wang, Wenhua Zheng & Peter J. Little. (2011) TGF-β stimulates biglycan core protein synthesis but not glycosaminoglycan chain elongation via Akt phosphorylation in vascular smooth muscle. Growth Factors 29:5, pages 203-210.
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Articles from other publishers (17)

Danielle Kamato & Peter J. Little. 2023. Lipoproteins in Diabetes Mellitus. Lipoproteins in Diabetes Mellitus 319 336 .
Pragyi Shrestha, Saritha Adepu, Romain R. Vivès, Rana El Masri, Astrid Klooster, Fleur Kaptein, Wendy Dam, Stephan J. L. Bakker, Harry van Goor, Bart van de Sluis & Jacob van den Born. (2021) Hypercholesterolemia in Progressive Renal Failure Is Associated with Changes in Hepatic Heparan Sulfate - PCSK9 Interaction. Journal of the American Society of Nephrology 32:6, pages 1371-1388.
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Ying Zhou, Peter J. Little, Yingnan Cao, Hang T. Ta & Danielle Kamato. (2020) Lysophosphatidic acid receptor 5 transactivation of TGFBR1 stimulates the mRNA expression of proteoglycan synthesizing genes XYLT1 and CHST3. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1867:12, pages 118848.
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Danielle Kamato, Bich Hang Do, Narin Osman, Benjamin P. Ross, Raafat Mohamed, Suowen Xu & Peter J. Little. (2019) Smad linker region phosphorylation is a signalling pathway in its own right and not only a modulator of canonical TGF-β signalling. Cellular and Molecular Life Sciences 77:2, pages 243-251.
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Rizwana Afroz, Yingnan Cao, Muhamad Ashraf Rostam, Hang Ta, Suowen Xu, Wenhua Zheng, Narin Osman, Danielle Kamato & Peter J. Little. (2018) Signalling pathways regulating galactosaminoglycan synthesis and structure in vascular smooth muscle: Implications for lipoprotein binding and atherosclerosis. Pharmacology & Therapeutics 187, pages 88-97.
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Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman & Peter J. Little. (2018) Flavopiridol Inhibits TGF- β -Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 . Journal of Pharmacology and Experimental Therapeutics 365:1, pages 156-164.
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Camilla Mohlin, Kerstin Sandholm, Kristina N. Ekdahl & Bo Nilsson. (2017) The link between morphology and complement in ocular disease. Molecular Immunology 89, pages 84-99.
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Narges Sharifat, Ghorban Mohammad Zadeh, Mohammad-Ali Ghaffari, Parisa Dayati, Danielle Kamato, Peter J Little & Hossein Babaahmadi-Rezaei. (2017) Endothelin-1 (ET-1) stimulates carboxy terminal Smad2 phosphorylation in vascular endothelial cells by a mechanism dependent on ET receptors and de novo protein synthesis . Journal of Pharmacy and Pharmacology 69:1, pages 66-72.
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Muhamad A. Rostam, Danielle Kamato, Terence J. Piva, Wenhua Zheng, Peter J. Little & Narin Osman. (2016) The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle. Cellular Signalling 28:8, pages 956-966.
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Rebekah Bernard, Robel Getachew, Danielle Kamato, Lyna Thach, Narin Osman, Vincent Chan, Wenhua Zheng & Peter J Little. (2016) Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response. Journal of Pharmacy and Pharmacology 68:3, pages 368-378.
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Othman Al Gwairi, Lyna Thach, Wenhua Zheng, Narin Osman & Peter J. Little. (2016) Cellular and Molecular Pathology of Age-Related Macular Degeneration: Potential Role for Proteoglycans. Journal of Ophthalmology 2016, pages 1-7.
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Narin Osman & Peter J. Little. 2014. Lipoproteins in Diabetes Mellitus. Lipoproteins in Diabetes Mellitus 215 229 .
Danielle Kamato, Micah L. Burch, Terrence J. Piva, Hossein Babaahmadi Rezaei, Muhamad Ashraf Rostam, Suowen Xu, Wenhua Zheng, Peter J. Little & Narin Osman. (2013) Transforming growth factor-β signalling: Role and consequences of Smad linker region phosphorylation. Cellular Signalling 25:10, pages 2017-2024.
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Micah L. Burch, Wenhua Zheng & Peter J. Little. (2010) Smad linker region phosphorylation in the regulation of extracellular matrix synthesis. Cellular and Molecular Life Sciences 68:1, pages 97-107.
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Sundy N.Y. YANG, Micah L. BURCH, Lisa R. TANNOCK, Stephen EVANKO, Narin OSMAN & Peter J. LITTLE. (2010) Transforming growth factor‐β regulation of proteoglycan synthesis in vascular smooth muscle: Contribution to lipid binding and accelerated atherosclerosis in diabetes. Journal of Diabetes 2:4, pages 233-242.
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Robel Getachew, Mandy L. Ballinger, Micah L. Burch, Julianne J. Reid, Levon M. Khachigian, Thomas N. Wight, Peter J. Little & Narin Osman. (2010) PDGF β-Receptor Kinase Activity and ERK1/2 Mediate Glycosaminoglycan Elongation on Biglycan and Increases Binding to LDL. Endocrinology 151:9, pages 4356-4367.
Crossref
Micah L. Burch, Sundy N. Y. Yang, Mandy L. Ballinger, Robel Getachew, Narin Osman & Peter J. Little. (2010) TGF-β stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad2. Cellular and Molecular Life Sciences 67:12, pages 2077-2090.
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