Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation

References

• Ballinger ML, Ivey ME, Osman N, Thomas WG, Little PJ. (2009). Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL. Atherosclerosis (In Press).
   Google Scholar
• Ballinger ML, Nigro J, Frontanilla KV, Dart AM, Little PJ. (2004). Regulation of glycosaminoglycan structure and atherogenesis. Cell Mol Life Sci 61: 1296–306.
   PubMed Web of Science ®Google Scholar
• Berrou E, Breton M, Deudon E, Picard J. (1991). Stimulation of large proteoglycan synthesis in cultured smooth muscle cells from pig aorta by endothelial cell-conditioned medium. J Cell Physiol 149: 436–43.
   PubMed Web of Science ®Google Scholar
• Camejo G, Hurt E, Romano M. (1985). Properties of lipoprotein complexes isolated by affinity chromatography from human aorta. Biomed Biochim Acta 44: 389–401.
   PubMedGoogle Scholar
• Campbell SC, Schwartz NB. (1988). Kinetics of intracellular processing of chondroitin sulphate proteoglycan core protein and other matrix components. J Cell Biol 106: 2191–202.
   PubMed Web of Science ®Google Scholar
• Chang MY, Potter-Perigo S, Tsoi C, Chait A, Wight TN. (2000). Oxidized low density lipoproteins regulate synthesis of monkey aortic smooth muscle cell proteoglycans that have enhanced native low density lipoprotein binding properties. J Biol Chem 275: 4766–73.
   PubMed Web of Science ®Google Scholar
• Chang Y, Yanagishita M, Hascall VC, Wight TN. (1983). Proteoglycans synthesized by smooth muscle cells derived from monkey (Macaca nemestrina) aorta. J Biol Chem 258: 5679–88.
   PubMed Web of Science ®Google Scholar
• Dadlani H, Ballinger ML, Osman N, Getachew R, Little PJ. (2008). Smad and p38 MAP kinase-mediated signalling of proteoglycan synthesis in vascular smooth muscle. J Biol Chem 283: 7844–52.
   PubMed Web of Science ®Google Scholar
• Fritz TA, Esko JD. (2001). Xyloside priming of glycosaminoglycan biosynthesis and inhibition of proteoglycan assembly. In: Iozzo RV, editor. Proteoglycan protocols. Totowa, NJ: Humana Press Inc, 317–24.
   Google Scholar
• Hascall VC, Heinegard DK, Wight TN. (1991). Proteoglycans: Metabolism and pathology. In: Hay ED, editor. Cell biology of extracellular matrix. New York: Plenum Press, 149–75.
   Google Scholar
• Hirschberg CB, Robbins PW, Abeijon C. (1998). Transporters of nucleotide sugars, ATP, and nucleotide sulphate in the endoplasmic reticulum and Golgi apparatus. Annu Rev Biochem 67: 49–69.
   PubMed Web of Science ®Google Scholar
• Ivey ME, Little PJ. (2008). Thrombin regulates vascular smooth muscle cell proteoglycan synthesis via PAR-1 and multiple downstream signalling pathways. Thromb Res 123: 288–297.
   Web of Science ®Google Scholar
• Izumikawa T, Uyama T, Okuura Y, Sugahara K, Kitagawa H. (2007). Involvement of chondroitin sulphate synthase-3 (chondroitin synthase–2) in chondroitin polymerization through its interaction with chondroitin synthase-1 or chondroitin- polymerizing factor. Biochem J 403: 545–52.
   PubMed Web of Science ®Google Scholar
• Kitagawa H, Izumikawa T, Uyama T, Sugahara K. (2003). Molecular cloning of a chondroitin polymerizing factor that cooperates with chondroitin synthase for chondroitin polymerization. J Biol Chem 278: 23666–71.
   PubMed Web of Science ®Google Scholar
• Laemmli UK. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680–5.
   PubMed Web of Science ®Google Scholar
• Linhardt RJ, Toida T. (2004). Role of glycosaminoglycans in cellular communication. Acc Chem Res 37: 431–8.
   PubMed Web of Science ®Google Scholar
• Little PJ, Ballinger ML, Burch ML, Osman N. (2008a). Biosynthesis of natural and hyperelongated chondroitin sulphate glycosaminoglycans: new insights into an elusive process. Open Biochem J 2: 135–42.
   PubMedGoogle Scholar
• Little PJ, Ballinger ML, Osman N. (2007). Vascular wall proteoglycan synthesis and structure as a target for the prevention of atherosclerosis. Vasc Health Risk Man 3: 1–8.
   PubMedGoogle Scholar
• Little PJ, Osman N, O’Brien KD. (2008b). Hyperelongated biglycan: the surreptitious initiator of atherosclerosis. Current Opinion in Lipidology 19: 448–454.
   PubMed Web of Science ®Google Scholar
• Little PJ, Tannock L, Olin KL, Chait A, Wight TN. (2002). Proteoglycans synthesized by arterial smooth muscle cells in the presence of transforming growth factor-beta1 exhibit increased binding to LDLs. Arterioscler Thromb Vasc Biol 22: 55–60.
   PubMed Web of Science ®Google Scholar
• Nakashima Y, Fujii H, Sumiyoshi S, Wight TN, Sueishi K. (2007). Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration. Arterioscler Thromb Vasc Biol 27: 1159–65.
   PubMed Web of Science ®Google Scholar
• Nigro J, Ballinger M, Dilley R, Jennings G, Wight T, Little P. (2004). Fenofibrate modifies human vascular smooth muscle proteoglycans and reduces LDL binding. Diabetologia 47: 2105–13.
   PubMed Web of Science ®Google Scholar
• O’Brien KD, Olin KL, Alpers CE, Chiu W, Ferguson M, Hudkins K, Wight TN, Chait A. (1998). Comparison of apolipoprotein and proteoglycan deposits in human coronary atherosclerotic plaques. colocalization of biglycan with apolipoproteins. Circulation 98: 519–27.
   PubMed Web of Science ®Google Scholar
• Oorni K, Pentikainen MO, Ala-Korpela M, Kovanen PT. (2000). Aggregation, fusion, and vesicle formation of modified low density lipoprotein particles: molecular mechanisms and effects on matrix interactions. J Lipid Res 41: 1703–14.
   PubMed Web of Science ®Google Scholar
• Potter-Perigo S, Braun KR, Schonherr E, Wight TN. (1992). Altered proteoglycan synthesis via the false acceptor pathway can be dissociated from beta-D-xyloside inhibition of proliferation. Arch Biochem Biophys 297: 101–9.
   PubMed Web of Science ®Google Scholar
• Ross R. (1993). The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362: 801–9.
   PubMed Web of Science ®Google Scholar
• Sato T, Gotoh M, Kiyohara K, Akashima T, Iwasaki H, Kameyama A, Mochizuki H, Yada T, Inaba N, Togayachi A, Kudo T, Asada M, Watanabe H, Imamura T, Kimata K, Narimatsu H. (2003). Differential roles of two N-acetylgalactosaminyltransferases, CSGalNAcT-1, and a novel enzyme, CSGalNAcT-2. Initiation and elongation in synthesis of chondroitin sulphate. J Biol Chem 278: 3063–71.
   PubMed Web of Science ®Google Scholar
• Schonherr E, Jarvelainen HT, Kinsella MG, Sandell LJ, Wight TN. (1993). Platelet-derived growth factor and transforming growth factor-beta 1 differentially affect the synthesis of biglycan and decorin by monkey arterial smooth muscle cells. Arterioscler Thromb 13: 1026–36.
   PubMedGoogle Scholar
• Schonherr E, Jarvelainen HT, Sandell LJ, Wight TN. (1991). Effects of platelet-derived growth factor and transforming growth factor-beta 1 on the synthesis of a large versican-like chondroitin sulphate proteoglycan by arterial smooth muscle cells. J Biol Chem 266: 17640–7.
   PubMed Web of Science ®Google Scholar
• Schonherr E, Kinsella MG, Wight TN. (1997). Genistein selectively inhibits platelet-derived growth factor-stimulated versican biosynthesis in monkey arterial smooth muscle cells. Arch Biochem Biophys 339: 353–61.
   PubMed Web of Science ®Google Scholar
• Tabas I, Williams KJ, Boren J. (2007). Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications. Circulation 116: 1832–44.
   PubMed Web of Science ®Google Scholar
• Toma L, Pinhal MA, Dietrich CP, Nader HB, Hirschberg CB. (1996). Transport of UDP-galactose into the Golgi lumen regulates the biosynthesis of proteoglycans. J Biol Chem 271: 3897–901.
   PubMed Web of Science ®Google Scholar
• Ungefroren H, Groth S, Ruhnke M, Kalthoff H, Fandrich F. (2005). Transforming growth factor-beta (TGF-beta) type I receptor/ALK5-dependent activation of the GADD45beta gene mediates the induction of biglycan expression by TGF-beta. J Biol Chem 280: 2644–52.
   PubMed Web of Science ®Google Scholar
• Vijayagopal P, Ciolino HP, Berenson GS. (1992). Endothelial cell-conditioned medium modulates the synthesis and structure of proteoglycans in vascular smooth muscle cells. Biochim Biophys Acta 1135: 129–40.
   PubMed Web of Science ®Google Scholar
• Wight TN (1991). Dynamic iInteraction of proteoglycans. In: Gotlieb AI, editor. Atherosclerosis. New York: Plenum Press, 115–125.
   Google Scholar
• Wight TN, Hascall VC. (1983). Proteoglycans in primate arteries. III. Characterization of the proteoglycans synthesized by arterial smooth muscle cells in culture. J Cell Biol 96: 167–76.
   PubMed Web of Science ®Google Scholar
• Williams KJ, Tabas I. (1995). The response-to-retention hypothesis of early atherogenesis. Arterioscler Thromb Vasc Biol 15: 551–61.
   PubMed Web of Science ®Google Scholar
• Williams KJ, Tabas I. (1998). The response-to-retention hypothesis of atherogenesis reinforced. Curr Opin Lipidol 9: 471–4.
   PubMed Web of Science ®Google Scholar