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Research Article

Flavonolignan Production in Cell Suspension Culture of Silybum marianum

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Pages 876-882 | Accepted 27 May 2008, Published online: 20 Jan 2009

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Muhammad aamir Shehzad, Mubarak Ali Khan, Amir Ali, Sher Mohammad, Ahmed Noureldeen, Hadeer Darwish, Asif Ali, Ayaz Ahmad, Tariq Khan & Raham Sher Khan. (2021) Interactive effects of zinc oxide nano particles and different light regimes on growth and silymarin biosynthesis in callus cultures of Silybum marianum L.. Artificial Cells, Nanomedicine, and Biotechnology 49:1, pages 523-535.
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Shadi Rahimi, Tahereh Hasanloo, Farzaneh Najafi & Ramezan Ali Khavari-Nejad. (2012) Methyl jasmonate influence on silymarin production and plant stress responses in Silybum marianum hairy root cultures in a bioreactor. Natural Product Research 26:18, pages 1662-1667.
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S. Rahimi Ashtiani, T. Hasanloo & M. R. Bihamta. (2010) Enhanced production of silymarin by Ag+ elicitor in cell suspension cultures of Silybum marianum. Pharmaceutical Biology 48:6, pages 708-715.
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Articles from other publishers (18)

Asmaa M. Khalifa, Eman Abd-ElShafy, Rasha Abu-Khudir & Reda M. Gaafar. (2022) Influence of gamma radiation and phenylalanine on secondary metabolites in callus cultures of milk thistle (Silybum marianum L.). Journal of Genetic Engineering and Biotechnology 20:1.
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Roberto Marceddu, Lucia Dinolfo, Alessandra Carrubba, Mauro Sarno & Giuseppe Di Miceli. (2022) Milk Thistle (Silybum Marianum L.) as a Novel Multipurpose Crop for Agriculture in Marginal Environments: A Review. Agronomy 12:3, pages 729.
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Samantha Drouet & Christophe Hano. 2021. Antioxidants - Benefits, Sources, Mechanisms of Action. Antioxidants - Benefits, Sources, Mechanisms of Action.
Hoda A.S. El-Garhy, Hassan S.A. Sherif, Sara M. Soliman, Shimaa A. Haredy & Mercedes Bonfill. (2021) Effect of gamma rays and colchicine on silymarin production in cell suspension cultures of Silybum marianum: A transcriptomic study of key genes involved in the biosynthetic pathway. Gene 790, pages 145700.
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Ahmed Abdelfattah Elateeq, Yanfang Sun, Winston Nxumalo & Ahmed M.M. Gabr. (2020) Biotechnological production of silymarin in Silybum marianum L.: A review. Biocatalysis and Agricultural Biotechnology 29, pages 101775.
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Hayam S. Ahmed, Abeer S. Moawad, Sameh F. AbouZid & Asmaa I. Owis. (2020) Salicylic acid increases flavonolignans accumulation in the fruits of hydroponically cultured Silybum marianum. Saudi Pharmaceutical Journal 28:5, pages 593-598.
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Mohamed Ramadan RadyMohamed Ramadan Rady. 2019. Plant Biotechnology and Medicinal Plants. Plant Biotechnology and Medicinal Plants 97 147 .
M.R. Rady, M.M. Saker & M.A. Matter. (2018) In vitro culture, transformation and genetic fidelity of Milk Thistle. Journal of Genetic Engineering and Biotechnology 16:2, pages 563-572.
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Ahmed M.M. Gabr, Hassan Ghareeb, Haatem M. El Shabrawi, Iryna Smetanska & S.A. Bekheet. (2016) Enhancement of silymarin and phenolic compound accumulation in tissue culture of Milk thistle using elicitor feeding and hairy root cultures. Journal of Genetic Engineering and Biotechnology 14:2, pages 327-333.
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Lennart Poppe & Maike Petersen. (2016) Variation in the flavonolignan composition of fruits from different Silybum marianum chemotypes and suspension cultures derived therefrom. Phytochemistry 131, pages 68-75.
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María Torres & Purificación Corchete. (2016) Gene expression and flavonolignan production in fruits and cell cultures of Silybum marianum. Journal of Plant Physiology 192, pages 111-117.
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Mubarak Ali Khan, Bilal Haider Abbasi, Naseer Ali Shah, Buhara Yücesan & Huma Ali. (2015) Analysis of metabolic variations throughout growth and development of adventitious roots in Silybum marianum L. (Milk thistle), a medicinal plant. Plant Cell, Tissue and Organ Culture (PCTOC) 123:3, pages 501-510.
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Daniel Prieto & Purificación Corchete. (2014) Transport of flavonolignans to the culture medium of elicited cell suspensions of Silybum marianum. Journal of Plant Physiology 171:2, pages 63-68.
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Mubarak Ali Khan, Bilal Haider Abbasi, Nisar Ahmed & Huma Ali. (2013) Effects of light regimes on in vitro seed germination and silymarin content in Silybum marianum. Industrial Crops and Products 46, pages 105-110.
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Ahlam Elwekeel, Sameh AbouZid, Nadia Sokkar & Ahlam Elfishway. (2012) Studies on flavanolignans from cultured cells of Silybum marianum. Acta Physiologiae Plantarum 34:4, pages 1445-1449.
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Ahlam Elwekeel, Ahlam Elfishway & Sameh AbouZid. (2012) Enhanced accumulation of flavonolignans in Silybum marianum cultured roots by methyl jasmonate. Phytochemistry Letters 5:2, pages 393-396.
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Bilal Haider Abbasi, Mubarak Ali Khan, Tariq Mahmood, Mushtaq Ahmad, Muhammad Fayyaz Chaudhary & Mir Ajab Khan. (2010) Shoot regeneration and free-radical scavenging activity in Silybum marianum L.. Plant Cell, Tissue and Organ Culture (PCTOC) 101:3, pages 371-376.
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Tahereh Hasanloo, Roshanak Sepehrifar, Hassan Rahnama & Mohammad Reza Shams. (2009) Evaluation of the yeast-extract signaling pathway leading to silymarin biosynthesis in milk thistle hairy root culture. World Journal of Microbiology and Biotechnology 25:11, pages 1901-1909.
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