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Pharmaceutical Biology Volume 60, 2022 - Issue 1
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Research Article

A comprehensive study on the relieving effect of Lilium brownii on the intestinal flora and metabolic disorder in p-chlorphenylalanine induced insomnia rats

Yanpo Sia Department of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, ChinaView further author information
,
Wenjun Weia Department of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, ChinaView further author information
,
Xiaohui Chena Department of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, ChinaView further author information
,
Xiaolong Xiea Department of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, ChinaView further author information
,
Tao Guoa Department of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-4398-361XView further author information
ORCID Icon,
Yohei Sasakib Graduate School of Medical Sciences, Kanazawa University, Kanazawa City, JapanView further author information
,
Youbo Zhangc State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing, ChinaView further author information
,
Lili Wanga Department of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, ChinaView further author information
,
Fei Zhanga Department of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, ChinaView further author information
&
Shuying Fengd Medical College, Henan University of Chinese Medicine, Zhengzhou, ChinaCorrespondence[email protected]
View further author information
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Pages 131-143 | Received 09 Sep 2021, Accepted 10 Dec 2021, Published online: 03 Jan 2022

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Yanpo Si, Chengcheng Hui, Tao Guo, Mengqi Liu, Xiaohui Chen, Chunhong Dong & Shuying Feng. (2023) Phellodendronoside A Exerts Anticancer Effects Depending on Inducing Apoptosis Through ROS/Nrf2/Notch Pathway and Modulating Metabolite Profiles in Hepatocellular Carcinoma. Journal of Hepatocellular Carcinoma 10, pages 935-948.
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Articles from other publishers (11)

Yu-Meng Liu, Jin-Cao Li, Yong-Fang Gu, Ren-Hong Qiu, Jia-Ying Huang, Rui Xue, Shuo Li, Yang Zhang, Kuo Zhang & You-Zhi Zhang. (2024) Cannabidiol Exerts Sedative and Hypnotic Effects in Normal and Insomnia Model Mice Through Activation of 5-HT1A Receptor. Neurochemical Research.
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Xinye Li, Chao He, Min Shen, Mingyun Wang, Jingwen Zhou, Dongying Chen, Tong Zhang & Yiqiong Pu. (2024) Effects of aqueous extracts and volatile oils prepared from Huaxiang Anshen decoction on p-chlorophenylalanine-induced insomnia mice. Journal of Ethnopharmacology 319, pages 117331.
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Wenjun Wei, Tao Guo, Wenguang Fan, Mengshan Ji, Yu Fu, Conglong Lian, Suiqing Chen, Wenjing Ma, Wenfang Ma & Shuying Feng. (2024) Integrative analysis of metabolome and transcriptome provides new insights into functional components of Lilii Bulbus. Chinese Herbal Medicines.
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Yu Yang, Zhe Chen, Guangli Yan, Ling Kong, Le Yang, Hui Sun, Ying Han, Jie Zhang & Xijun Wang. (2023) Mass spectrum oriented metabolomics for evaluating the efficacy and discovering the metabolic mechanism of Naoling Pian for insomnia. Journal of Pharmaceutical and Biomedical Analysis 236, pages 115756.
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Ling Mo, Huijuan Jing, Xiaojing Du, Chaochao Zhao, Yintao Lin, Jie Li & Hongxin Wang. (2023) Goat and cow milk differ in altering the microbiota composition and neurotransmitter levels in insomnia mouse models. Food & Function 14:14, pages 6526-6540.
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Haoran WANG, Yanqiu GU, Rahman KHALID, Xiaofei CHEN & Ting HAN. (2023) Herbal medicines for insomnia through regulating 5-hydroxytryptamine receptors: a systematic review. Chinese Journal of Natural Medicines 21:7, pages 483-498.
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Wanjun Long, Siyu Wang, Chengying Hai, Hengye Chen, Hui-Wen Gu, Xiao-Li Yin, Jian Yang & Haiyan Fu. (2023) UHPLC-QTOF-MS-based untargeted metabolomics revealing the differential chemical constituents and its application on the geographical origins traceability of lily bulbs. Journal of Food Composition and Analysis 118, pages 105194.
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Wanying Feng, Zhihua Yang, Yangxi Liu, Rui Chen, Zhihui Song, Guiyun Pan, Yuhang Zhang, Zehui Guo, Xinya Ding, Lu Chen & Yi Wang. (2023) Gut microbiota: A new target of traditional Chinese medicine for insomnia. Biomedicine & Pharmacotherapy 160, pages 114344.
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樱 罗. (2023) To Explore the Research Progress of Traditional Chinese Medicine in the Treatment of Insomnia Based on Intestinal Flora. Traditional Chinese Medicine 12:04, pages 823-828.
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Yanbo Liu, Zhen Li, Tianning Sun, Zhigang He, Hongbing Xiang & Jun Xiong. (2022) Gut microbiota-generated short-chain fatty acids are involved in para-chlorophenylalanine-induced cognitive disorders. Frontiers in Microbiology 13.
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Hong Yu, Hui Yu, Lengge Si, Husileng Meng, Wensheng Chen, Zhanli Wang & A. Gula. (2022) Influence of warm acupuncture on gut microbiota and metabolites in rats with insomnia induced by PCPA. PLOS ONE 17:4, pages e0267843.
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