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Research Article

Synthesis of some 4-arylidenamino-4H-1,2,4-triazole-3-thiols and their antituberculosis activity

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Pages 511-516 | Received 05 Nov 2006, Accepted 30 Nov 2006, Published online: 04 Oct 2008

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El Sayed H. El Ashry, El Sayed H. El Tamany, Mohy El Din Abd El Fattah, Mohamed R. E. Aly, Ahmed T. A. Boraei, M. Ahmed Mesaik, Omer M. Abdalla, Beenish Fatima, Almas Jabeen, Ahmed Shukrulla & Samreen Soomro. (2013) Immunomodulatory properties of S- and N-alkylated 5-(1H-indol-2-yl)-1,3,4-oxadiazole-2(3H)-thione. Journal of Enzyme Inhibition and Medicinal Chemistry 28:1, pages 105-112.
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Muhammad Nisar, Shafiq Ahmad Tariq, Inamullah Khan Marwat, Muhammad Raza Shah & Ihsan Ali Khan. (2009) Antibacterial, antifungal, insecticidal, cytotoxicity and phytotoxicity studies on Indigofera gerardiana. Journal of Enzyme Inhibition and Medicinal Chemistry 24:1, pages 224-229.
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Articles from other publishers (19)

Muawia M. Alqasaimeh, Abdel-Aziz M. Abu-Yamin, Suzan A. Matar, Ibrahim A. Sarairah, Mahmoud M. Salman & Randa M. Al-As'ad. (2024) Synthesis and characterization of a new Schiff-base derivative as an optical nickel (II) chemosensor and its antimicrobial activity. Journal of Photochemistry and Photobiology A: Chemistry 447, pages 115277.
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Jasneet Rana & R.P. Chaudhary. (2023) Excited state dynamics of 1,2,4-triazolyl-thio-pentane-2,4-dione system and their conversion to biologically active novel triazole-S-pyrazole hybrids. Journal of Molecular Structure 1291, pages 136015.
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Muawia Alqasaimeh, Abdel-Aziz Abu-Yamin, Suzan Matar, Khaled Al Khalyfeh, Tobias Rüffer, Heinrich Lang, Ibrahim A.M. Saraerah, Mahmoud Salman, Pawel Figiel, Grzegorz Leniec, Hazem Amarne & Deeb Taher. (2023) Preparation, spectroscopic investigation, biological activity and magnetic properties of three inner transition metal complexes based on (2-((p-tolylimino)methyl)phenol) Schiff base. Journal of Molecular Structure 1274, pages 134458.
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Muawia M. Alqasaimeh, Abdel-Aziz Abu-Yamin, Suzan A. Matter, Ibrahim A. Al-Saraireh & Mahmoud M. Salman. (2023) Synthesis, Characterization of Triazole Schiff-Base Derivatives as an Optical Nickel (Ii) Sensing Recognition and its Antimicrobial Activity. SSRN Electronic Journal.
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Ashraf A. Aly, Alaa A. Hassan, Maysa M. Makhlouf & Stefan Bräse. (2020) Chemistry and Biological Activities of 1,2,4-Triazolethiones—Antiviral and Anti-Infective Drugs. Molecules 25:13, pages 3036.
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Katharigatta N. Venugopala, Mohammed A. Khedr, Yarabahally R. Girish, Subhrajyoti Bhandary, Deepak Chopra, Mohamed A. Morsy, Bandar E. Aldhubiab, Pran Kishore Deb, Mahesh Attimarad, Anroop B. Nair, Nagaraja Sreeharsha, Rashmi V, Mahmoud Kandeel, Sabah H. Akrawi, Madhusudana Reddy M B, Sheena Shashikanth, Osama I. Alwassil & Viresh Mohanlall. (2020) Crystallography, in Silico Studies, and In Vitro Antifungal Studies of 2,4,5 Trisubstituted 1,2,3-Triazole Analogues. Antibiotics 9:6, pages 350.
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Javad Ghanaat, Mohammad A. Khalilzadeh, Daryoush Zareyee, Mohammadreza Shokouhimehr & Rajender S. Varma. (2019) Cell cycle inhibition, apoptosis, and molecular docking studies of the novel anticancer bioactive 1,2,4-triazole derivatives. Structural Chemistry 31:2, pages 691-699.
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Nooka Ratnam Appna, Ravi Kumar Nagiri, Raghu Babu Korupolu, Sirisha Kanugala, Ganesh Kumar Chityal, Ganapathi Thipparapu & Narsaiah Banda. (2019) Design and synthesis of novel 4-hydrazone functionalized/1,2,4-triazole fused pyrido[2,3-d]pyrimidine derivatives, their evaluation for antifungal activity and docking studies. Medicinal Chemistry Research 28:9, pages 1509-1528.
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Farzanabi Shaikh, Samundeeswari L. Shastri, Nirmala S. Naik, Rashmi Kulkarni, Jyoti M. Madar, Lokesh A. Shastri, Shrinivas D. Joshi & Vinay Sunagar. (2019) Synthesis, Antitubercular and Antimicrobial Activity of 1,2,4‐Triazolidine‐3‐thione Functionalized Coumarin and Phenyl Derivatives and Molecular Docking Studies. ChemistrySelect 4:1, pages 105-115.
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Ramya Tokala, Swarna Bale, Ingle Pavan Janrao, Aluri Vennela, Niggula Praveen Kumar, Kishna Ram Senwar, Chandraiah Godugu & Nagula Shankaraiah. (2018) Synthesis of 1,2,4-triazole-linked urea/thiourea conjugates as cytotoxic and apoptosis inducing agents. Bioorganic & Medicinal Chemistry Letters 28:10, pages 1919-1924.
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Jeetendra Kumar Gupta & Pradeep Mishra. (2017) Pharmacological screening of some newly synthesized triazoles for H1 receptor antagonist activity. Medicinal Chemistry Research 26:10, pages 2260-2271.
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Ramazan Gup, Oktay Erer & Nefise Dilek. (2017) A rapid synthesis of 2-substituted 1,2,3- triazole-1-oxide derivative starting from 4-(methyl)isonitrosoacetophenone and its Ni(II) complex: Characterization, DNA binding and cleavage properties. Journal of Molecular Structure 1129, pages 142-151.
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Ahmed T. A. Boraei, El Sayed H. El Ashry & Axel Duerkop. (2016) Regioselectivity of the alkylation of S-substituted 1,2,4-triazoles with dihaloalkanes. Chemistry Central Journal 10:1.
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Rangappa S. Keri, Siddappa A. Patil, Srinivasa Budagumpi & Bhari Mallanna Nagaraja. (2015) Triazole: A Promising Antitubercular Agent. Chemical Biology & Drug Design 86:4, pages 410-423.
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Tetiana Matviiuk, Giorgia Mori, Christian Lherbet, Frédéric Rodriguez, Maria Rosalia Pasca, Marian Gorichko, Brigitte Guidetti, Zoia Voitenko & Michel Baltas. (2014) Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis. European Journal of Medicinal Chemistry 71, pages 46-52.
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El Sayed H. El Ashry, El Sayed H. El Tamany, Mohy El Din Abd El Fattah, Ahmed T.A. Boraei & Heba M. Abd El-Nabi. (2013) Regioselective synthesis, characterization and antimicrobial evaluation of S-glycosides and S,N-diglycosides of 1,2-Dihydro-5-(1H-indol-2-yl)-1,2,4-triazole-3-thione. European Journal of Medicinal Chemistry 66, pages 106-113.
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Guillermo R. Labadie, Agustina de la Iglesia & Héctor R. Morbidoni. (2011) Targeting tuberculosis through a small focused library of 1,2,3-triazoles. Molecular Diversity 15:4, pages 1017-1024.
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Navin B. Patel, Imran H. Khan & Smita D. Rajani. (2010) Antimycobacterial and antimicrobial study of new 1,2,4‐triazoles with benzothiazoles. Archiv der Pharmazie 343:11-12, pages 692-699.
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Marzena Rządkowska. (2009) Synthesis of new derivatives of 4-amino-1,2,4-triazoleSynteza nowych pochodnych 4-amino-1,2,4-triazolu. Annales UMCS, Pharmacia 22:2, pages 61-63.
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