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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 23, 2008 - Issue 1
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Research Article

Synthesis and biological evaluation of novel angular fused Pyrrolocoumarins

Christos Kontogiorgis Laboratory of Organic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece
,
Konstantinos E. Litinas Laboratory of Organic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece
,
Aristea Makri Laboratory of Organic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece
,
Demetrios N. Nicolaides Laboratory of Organic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece
,
Anastasia Vronteli Laboratory of Organic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece
,
Dimitra J. Hadjipavlou-Litina Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece
,
Eleni Pontiki Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece
&
Asimoula Siohou Department of Medical Laboratories, Alexandrion Technological Educational Foundation of Thessaloniki, Thessaloniki, 57400, Greece
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Pages 43-49 | Received 12 Feb 2007, Accepted 23 Mar 2007, Published online: 04 Oct 2008

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Sahar A. Ali, Samir Mohamed Awad, Ahmed Mohammed Said, Shahenda Mahgoub, Heba Taha & Naglaa Mohamed Ahmed. (2020) Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 847-863.
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Michael G. Kallitsakis, Dimitra J. Hadjipavlou-Litina & Konstantinos E. Litinas. (2013) Synthesis of purine homo-N-nucleosides modified with coumarins as free radicals scavengers*. Journal of Enzyme Inhibition and Medicinal Chemistry 28:4, pages 765-775.
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Konstantinos E. Litinas, Alexandros Mangos, Thomas E. Nikkou & Dimitra J. Hadjipavlou-Litina. (2011) Synthesis and biological evaluation of fused oxepinocoumarins as free radicals scavengers. Journal of Enzyme Inhibition and Medicinal Chemistry 26:6, pages 805-812.
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Zrinka Rajić, Ivana Perković, Ivan Butula, Branka Zorc, Dimitra Hadjipavlou-Litina, Eleni Pontiki, Stjepan Pepeljnjak & Ivan Kosalec. (2009) Synthesis and biological evaluation of O-methyl and O-ethyl NSAID hydroxamic acids. Journal of Enzyme Inhibition and Medicinal Chemistry 24:5, pages 1179-1187.
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Articles from other publishers (11)

Thomas D. Balalas, Maria G. Kanelli, Catherine Gabriel, Eleni Pontiki, Dimitra J. Hadjipavlou-Litina & Konstantinos E. Litinas. (2022) Pd-Catalyzed N–H or C–H Functionalization/Oxidative Cyclization for the Efficient Synthesis of N-Aryl-Substituted [3,4]-Fused Pyrrolo­coumarins. Synthesis 54:12, pages 2894-2806.
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Karthik Kumara, Malledevarapura Gurumurthy Prabhudeva, Channa Basappa Vagish, Hamse Kameshwar Vivek, Kuriya Madavu Lokanatha Rai, Neratur Krishnappagowda Lokanath & Kariyappa Ajay Kumar. (2021) Design, synthesis, characterization, and antioxidant activity studies of novel thienyl-pyrazoles. Heliyon 7:7, pages e07592.
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Mengjie Xiao, Dengfeng Xu, Weihong Liang, Wenyu Wu, Albert S. C. Chan & Junling Zhao. (2018) Organocatalytic Enantioselective Friedel-Crafts Alkylation/Lactonization Reaction of Hydroxyindoles with Methyleneoxindoles. Advanced Synthesis & Catalysis 360:5, pages 917-924.
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Cheng Wang, Tao Wang, Limin Huang, Yajing Hou, Wen Lu & Huaizhen He. (2016) Facile synthetic approach for 5-aryl-9-hydroxypyrano [3,2-f] indole-2(8H)-one. Arabian Journal of Chemistry 9:6, pages 882-890.
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Stella Manta, Dimitra-Niki Gkaragkouni, Eleni Kaffesaki, Petros Gkizis, Dimitra Hadjipavlou-Litina, Eleni Pontiki, Jan Balzarini, Wim Dehaen & Dimitri Komiotis. (2014) A novel and easy two-step, microwave-assisted method for the synthesis of halophenyl pyrrolo[2,3-b]quinoxalines via their pyrrolo precursors. Evaluation of their bioactivity. Tetrahedron Letters 55:11, pages 1873-1876.
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K. C. Majumdar, Nirupam De, Biswajit Sinha & B. Roy. (2011) Synthesis of 3-iodopyrrolocoumarins via iodine-induced 5-endo-dig electrophilic cyclization. Monatshefte für Chemie - Chemical Monthly 143:7, pages 1067-1073.
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K.C. Majumdar, Somjit Hazra & B. Roy. (2011) Gold-catalyzed heteroannulation and allyl migration: synthesis of highly functionalized indole derivatives. Tetrahedron Letters 52:50, pages 6697-6701.
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A.-M. Katsori, M. Chatzopoulou, K. Dimas, C. Kontogiorgis, A. Patsilinakos, T. Trangas & D. Hadjipavlou-Litina. (2011) Curcumin analogues as possible anti-proliferative & anti-inflammatory agents. European Journal of Medicinal Chemistry 46:7, pages 2722-2735.
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Konstantinos E. Litinas & Theodoros S. Symeonidis. (2010) Convenient synthesis of fused pyrano[3,2-h]- and furo[3,2-h]benzo[f]coumarins from naphthalene-2,3-diol. Tetrahedron 66:6, pages 1289-1293.
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Andreas Thalassitis, Dimitra J. Hadjipavlou-Litina, Konstantinos E. Litinas & Panagiotis Miltiadou. (2009) Synthesis of modified homo-N-nucleosides from the reactions of mesityl nitrile oxide with 9-allylpurines and their influence on lipid peroxidation and thrombin inhibition. Bioorganic & Medicinal Chemistry Letters 19:22, pages 6433-6436.
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Theodoros Symeonidis, Michael Chamilos, Dimitra J. Hadjipavlou-Litina, Michael Kallitsakis & Konstantinos E. Litinas. (2009) Synthesis of hydroxycoumarins and hydroxybenzo[f]- or [h]coumarins as lipid peroxidation inhibitors. Bioorganic & Medicinal Chemistry Letters 19:4, pages 1139-1142.
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