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Research Article

Benzo(a)pyrene-induced genotoxicity: Attenuation by farnesol in a mouse model

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Pages 888-894 | Received 09 Mar 2007, Accepted 21 Apr 2007, Published online: 20 Oct 2008

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Gyllyandeson De Araújo Delmondes, Izabel Cristina Santiago Lemos, Diógenes De Queiroz Dias, Glacithane Lins Da Cunha, Isaac Moura Araújo, Roseli Barbosa, Henrique Douglas Melo Coutinho, Cícero Francisco Bezerra Felipe, José Maria Barbosa-Filho, Natanael Teles Ramos De Lima, Irwin Rose Alencar De Menezes & Marta Regina Kerntopf. (2020) Pharmacological applications of farnesol (C15H26O): a patent review. Expert Opinion on Therapeutic Patents 30:3, pages 227-234.
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R AliA ShahidN AliSK HasanF MajedS Sultana. (2016) Amelioration of Benzo[a]pyrene-induced oxidative stress and pulmonary toxicity by Naringenin in Wistar rats: A plausible role of COX-2 and NF-κB. Human & Experimental Toxicology 36:4, pages 349-364.
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Ayaz Shahid, Rashid Ali, Nemat Ali, Syed Kazim Hasan, Preeti Bernwal, Shekh Mohammad Afzal, Abul Vafa & Sarwat Sultana. (2016) Modulatory effects of catechin hydrate against genotoxicity, oxidative stress, inflammation and apoptosis induced by benzo(a)pyrene in mice. Food and Chemical Toxicology 92, pages 64-74.
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Ayaz Shahid, Rashid Ali, Nemat Ali, Syed Kazim Hasan, Summya Rashid, Ferial Majed & Sarwat Sultana. (2016) Attenuation of genotoxicity, oxidative stress, apoptosis and inflammation by rutin in benzo(a)pyrene exposed lungs of mice: plausible role of NF-κB, TNF-α and Bcl-2. Journal of Complementary and Integrative Medicine 13:1, pages 17-29.
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Joung Hyuck Joo, Eiichiro Ueda, Carl D. Bortner, Xiao-Ping Yang, Grace Liao & Anton M. Jetten. (2015) Farnesol activates the intrinsic pathway of apoptosis and the ATF4-ATF3-CHOP cascade of ER stress in human T lymphoblastic leukemia Molt4 cells. Biochemical Pharmacology 97:3, pages 256-268.
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Germán Chamorro-CevallosLeticia Garduño-SicilianoElizdath Martínez-GaleroAngélica Mojica-VillegasNicole PagesGabriela Gutiérrez-Salmeán. (2014) The Protective Effect of Dietary Arthrospira ( Spirulina ) maxima Against Mutagenicity Induced by Benzo[alpha]pyrene in Mice . Journal of Medicinal Food 17:5, pages 527-534.
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Robert Tisserand & Rodney Young. 2014. Essential Oil Safety. Essential Oil Safety 483 647 .
S T Ahmad & S Sultana. (2011) Tannic acid mitigates cisplatin-induced nephrotoxicity in mice. Human & Experimental Toxicology 31:2, pages 145-156.
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Jie-Qiong Ma, Chan-Min Liu, Zhi-Hong Qin, Ji-Hong Jiang & Yun-Zhi Sun. (2011) Ganoderma applanatum terpenes protect mouse liver against benzo(α)pyren-induced oxidative stress and inflammation. Environmental Toxicology and Pharmacology 31:3, pages 460-468.
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Joung Hyuck Joo & Anton M. Jetten. (2010) Molecular mechanisms involved in farnesol-induced apoptosis. Cancer Letters 287:2, pages 123-135.
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