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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 23, 2008 - Issue 2
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Research Article

A quantitative structure-activity relationship study of novel, potent, orally active, selective VEGFR-2 and PDGFRα tyrosine kinase inhibitors: Derivatives of N-Phenyl-N′-{4-(4-quinolyloxy)phenyl}urea as antitumor agents

B. K. Sharma Department of Chemistry, S K Government College, Sikar, 332 001
,
S. K. Sharma Department of Chemistry, S K Government College, Sikar, 332 001
,
P. Singh Department of Chemistry, S K Government College, Sikar, 332 001
&
Susheela Sharma Department of Engineering Chemistry, Sobhasaria Engineering College, Sikar, 332 021, INDIA
Pages 168-173 | Received 17 Jan 2007, Accepted 01 Apr 2007, Published online: 04 Oct 2008

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Mwadham. M. Kabanda & Kemoabetswe R. N. Serobatse. (2018) A DFT study on the addition and abstraction reactions of thiourea with hydroxyl radical. Journal of Sulfur Chemistry 39:1, pages 23-46.
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Min Sun, Youguang Zheng, Hongtao Wei, Junqing Chen & Min Ji. (2009) QSAR studies on 4-anilino-3-quinolinecarbonitriles as Src kinase inhibitors using robust PCA and both linear and nonlinear models. Journal of Enzyme Inhibition and Medicinal Chemistry 24:5, pages 1109-1116.
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Articles from other publishers (11)

Muhammad Yasir Mehboob, Riaz Hussain, Saba Jamil, Mahmood Ahmed, Muhammad Usman Khan, Muhammad Haroon & Muhammad Ramzan Saeed Ashraf Janjua. (2022) Physical‐organic aspects along with linear and nonlinear optical properties of benzene sulfonamide compounds: In silico analysis. Journal of Physical Organic Chemistry 35:4.
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Samia Kausar, Ataf Ali Altaf, Muhammad Hamayun, Amin Badshah & Abdul Razzaq. 2021. Photophysics, Photochemical and Substitution Reactions - Recent Advances. Photophysics, Photochemical and Substitution Reactions - Recent Advances.
Kemoabetswe R.N. Serobatse & Mwadham M. Kabanda. (2017) An appraisal of the hydrogen atom transfer mechanism for the reaction between thiourea derivatives and radical: A case-study of dimethylthiourea and diethylthiourea . Computational and Theoretical Chemistry 1101, pages 83-95.
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Muhammad Naveed Umar, Mohammad Shoaib, Mohammad Sadiq, Muhammad Ayaz, Sumaira Miskeen, Ismail Shah, Imran Khan, Haroon Ur Rahid, Ikram Ilahi & Sher Wali Khan. (2016) Synthesis and Pharmacological Properties of 1,3-Bis[(S)Phenylethyl]Imidazolidine-2-Thione. Pharmaceutical Chemistry Journal 50:6, pages 382-387.
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Touhami Lanez & Elhafnaoui Lanez. (2016) A Molecular Docking Study of N-Ferrocenylmethylnitroanilines as Potential Anticancer Drugs. International Journal of Pharmacology, Phytochemistry and Ethnomedicine 2, pages 5-12.
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Jacek Panek, Magdalena Frąc & Nina Bilińska-Wielgus. (2016) Comparison of Chemical Sensitivity of Fresh and Long-Stored Heat Resistant Neosartorya fischeri Environmental Isolates Using BIOLOG Phenotype MicroArray System. PLOS ONE 11:1, pages e0147605.
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Rino Ragno, Flavio Ballante, Adele Pirolli, Richard B. WickershamIIIIII, Alexandros Patsilinakos, Stéphanie Hesse, Enrico Perspicace & Gilbert Kirsch. (2015) Vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors: development and validation of predictive 3-D QSAR models through extensive ligand- and structure-based approaches. Journal of Computer-Aided Molecular Design 29:8, pages 757-776.
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Shunlai Li, Rutao Zhang & Hongguang Du. (2013) 3D-QSAR Study on a Series of VEGFR-2 Kinase Inhibitors: 3-Pyrrole Substituted Indolin-2-Ones Compounds. Journal of Chemistry 2013, pages 1-8.
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Serkan Yavuz & Hilal Yıldırım. (2013) Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities. Journal of Chemistry 2013, pages 1-7.
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Ashutosh Kumar Pandey, Omprakash Tanwar, Girdhar Singh Deora, Chandrabose Karthikeyan, N. S. Hari Narayana Moorthy & Piyush Trivedi. (2011) Modeling VEGFR kinase inhibition of aminopyrazolopyridine urea derivatives using topological and physicochemical descriptors: a quantitative structure activity analysis study. Medicinal Chemistry Research 21:12, pages 3958-3964.
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Doddakunche S. Prasanna, Chandagirikoppal V. Kavitha, Kambappa Vinaya, Somasagara R. Ranganatha, Byregowda Raghava, Yelekere C. Sunil Kumar, Sathees C. Raghavan & Kanchugarakoppal S. Rangappa. (2010) Synthesis and Antileukemic Activity of 1-(( S )-2-Amino-4,5,6,7-tetrahydrobenzo[ d ]thiazol-6-yl)-3-(substituted phenyl)urea Derivatives . Bulletin of the Chemical Society of Japan 83:6, pages 689-697.
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