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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 23, 2008 - Issue 6
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Short Communication

Norditerpenoid alkaloids from the roots of Aconitum heterophyllum Wall with antibacterial activity

Manzoor Ahmad H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan,Correspondence[email protected]
,
Waqar Ahmad Faculty of Pharmacy, Institute of Pharmaceutical Sciences, University of Karachi, Karachi 75270, Pakistan, and
,
Mansoor Ahmad Faculty of Pharmacy, Institute of Pharmaceutical Sciences, University of Karachi, Karachi 75270, Pakistan, and
,
Muhammad Zeeshan H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan,
,
Obaidullah Department of Pharmacy, University of Peshawar, Peshawar 25120, Pakistan
&
Farzana Shaheen H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan,
Pages 1018-1022 | Received 15 Aug 2007, Accepted 25 Sep 2007, Published online: 20 Oct 2008

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Hanif Ahmad, Shujaat Ahmad, Syed Adnan Ali Shah, Hidayat Ullah Khan, Farman Ali Khan, Mumtaz Ali, Abdul Latif, Farzana Shaheen & Manzoor Ahmad. (2018) Selective dual cholinesterase inhibitors from Aconitum laeve. Journal of Asian Natural Products Research 20:2, pages 172-181.
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Nidhi S. Belwal, Barkha Kamal, Vikas Sharma, Sanjay Gupta, Anoop Kumar Dobriyal & Vikash S. Jadon. (2016) Production of genetically uniform plants from shoot tips of Aconitum heterophyllum Wall. – a critically endangered medicinal herb. The Journal of Horticultural Science and Biotechnology 91:5, pages 529-535.
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Sekhar Tiwari, Puja Acharya, Bharat Solanki, Anish Kumar Sharma & Sandeep Rawat. (2023) A review on efforts for improvement in medicinally important chemical constituents inAconitum through biotechnological interventions. 3 Biotech 13:6.
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Anna MathewK. S. ChandrashekarAnoop KishoreVasudev PaiH. N Aswatha RamRamadevi Pemmereddy. (2023) Therapeutic Potential of Aconitum heterophyllum: A Review on Phyto-pharmacological properties. Research Journal of Pharmacy and Technology, pages 470-476.
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Lijun Zhang, Xiaolou Miao, Yun Li, Fangdi Hu, Dongni Ma, Zhuanping Zhang, Quanming Sun, Yuanfeng Zhu & Qingli Zhu. (2022) Traditional processing, uses, phytochemistry, pharmacology and toxicology of Aconitum sinomontanum Nakai: A comprehensive review. Journal of Ethnopharmacology 293, pages 115317.
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Tareq A. Wani, Zahoor A. Kaloo & Nisar A. Dangroo. (2022) Aconitum heterophyllum Wall. ex Royle: A critically endangered medicinal herb with rich potential for use in medicine. Journal of Integrative Medicine 20:2, pages 104-113.
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Li MI, Yu-Chen LI, Meng-Ru SUN, Pei-Lin ZHANG, Yi LI & Hua YANG. (2021) A systematic review of pharmacological activities, toxicological mechanisms and pharmacokinetic studies on Aconitum alkaloids. Chinese Journal of Natural Medicines 19:7, pages 505-520.
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Yali Wang, Dejuan Sun, Yanmei Chen, Jinyu Xu, Yang Xu, Xinyi Yue, Jingming Jia, Hua Li & Lixia Chen. (2021) Alkaloids of Delphinium grandiflorum and their implication to H2O2-induced cardiomyocytes injury. Bioorganic & Medicinal Chemistry 37, pages 116113.
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Sanjay Kumar, Mohammad Suhail Javed, Pawan Kumar, Sachin Gupta, Rishendra Kumar & Pramod Kumar Singh. (2021) In-vitro antifungal and anti-bacterial activity of chloroform extract from tubers of Aconitum laeve Royle: Endangered species, India. Materials Today: Proceedings 34, pages 563-568.
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Lei Pang, Chun-Yan Liu, Guo-Hua Gong & Zhe-Shan Quan. (2020) Synthesis, in vitro and in vivo biological evaluation of novel lappaconitine derivatives as potential anti-inflammatory agents. Acta Pharmaceutica Sinica B 10:4, pages 628-645.
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Ankit Singh, Robbie Hart, Sudeep Chandra, M. C. Nautiyal & Alexander K. Sayok. (2019) Traditional Herbal Knowledge among the Inhabitants: A Case Study in Urgam Valley of Chamoli Garhwal, Uttarakhand, India. Evidence-Based Complementary and Alternative Medicine 2019, pages 1-21.
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Hasandeep Singh, Sakshi Bhushan, Rohit Arora, Harpal Singh Buttar, Saroj Arora & Balbir Singh. (2017) Alternative treatment strategies for neuropathic pain: Role of Indian medicinal plants and compounds of plant origin-A review. Biomedicine & Pharmacotherapy 92, pages 634-650.
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Muhammad Jamil Ahmed & Tanweer Akhtar. (2016) Indigenous knowledge of the use of medicinal plants in Bheri, Muzaffarabad, Azad Kashmir, Pakistan. European Journal of Integrative Medicine 8:4, pages 560-569.
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Tengfei Xu, Shu Liu, Lulu Meng, Zifeng Pi, Fengrui Song & Zhiqiang Liu. (2016) Bioactive heterocyclic alkaloids with diterpene structure isolated from traditional Chinese medicines. Journal of Chromatography B 1026, pages 56-66.
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Jambey Tsering, Hui Tag, Baikuntha Jyoti Gogoi & Vijay Veer. 2016. Herbal Insecticides, Repellents and Biomedicines: Effectiveness and Commercialization. Herbal Insecticides, Repellents and Biomedicines: Effectiveness and Commercialization 189 203 .
Wenxiu Sun, Shi Zhang, Hong Wang & Yunpu Wang. (2015) Synthesis, characterization and antinociceptive properties of the lappaconitine salts. Medicinal Chemistry Research 24:9, pages 3474-3482.
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Yi Dong, Nana Du, Xueyuan Li, Litao Zheng & Gang Liu. (2015) Tandem Chloropalladation/Cyclization and Dearomative Cyclization toward Functionalized Tricyclic Bridged [3.2.1] Skeleton Compounds. Organic Letters 17:16, pages 4110-4113.
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Shupeng Yang, Huiyan Zhang, Ross C. Beier, Feifei Sun, Xingyuan Cao, Jianzhong Shen, Zhanhui Wang & Suxia Zhang. (2015) Comparative metabolism of Lappaconitine in rat and human liver microsomes and in vivo of rat using ultra high-performance liquid chromatography–quadrupole/time-of-flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 110, pages 1-11.
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Eric Nyirimigabo, Yanyan Xu, Yubo Li, Yuming Wang, Kojo Agyemang & Yanjun Zhang. (2015) A review on phytochemistry, pharmacology and toxicology studies of Aconitum . Journal of Pharmacy and Pharmacology 67:1, pages 1-19.
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Satyendra K Prasad, Damiki Laloo, Alakh N Sahu, Gopal Nath & Siva Hemalatha. (2014) Cryptocoryne spiralis , a substitute of Aconitum heterophyllum in the treatment of diarrhoea . Journal of Pharmacy and Pharmacology 66:12, pages 1808-1817.
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Neelma Munir, Wasqa Ijaz, Imran Altaf & Shagufta Naz. (2014) Evaluation of antifungal and antioxidant potential of two medicinal plants: Aconitum heterophyllum and Polygonum bistorta. Asian Pacific Journal of Tropical Biomedicine 4, pages S639-S643.
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Yoirentomba Meetei Sinam, Sanjeev Kumar, Sachin Hajare, Satyendra Gautam, Suchandra Chatterjee, Prasad S. Variyar, G.A. Shantibala Devi & Arun Sharma. (2012) Isolation and identification of antibacterial compound from Indo–Himalayan Aconitum nagarum. Asian Pacific Journal of Tropical Disease 2, pages S878-S882.
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Nidhi Srivastava, Vikas Sharma, Barkha Kamal, A.K. Dobriyal & Vikash S. Jadon. (2010) Polyphenolics Free DNA Isolation from Different Types of Tissues of Aconitum heterophyllum Wall-endangered Medicinal Species. Journal of Plant Sciences 5:4, pages 414-419.
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Phurpa Wangchuk, John B. Bremner, Samten, Brian W. Skelton, Allan H. White, Roonglawan Rattanajak & Sumalee Kamchonwongpaisan. (2010) Antiplasmodial activity of atisinium chloride from the Bhutanese medicinal plant, Aconitum orochryseum. Journal of Ethnopharmacology 130:3, pages 559-562.
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Feng-Peng Wang, Qiao-Hong Chen & Xiao-Yu Liu. (2010) Diterpenoid alkaloids. Natural Product Reports 27:4, pages 529.
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