3,752
Views
99
CrossRef citations to date
0
Altmetric
Research Article

Inhibition of dipeptidyl peptidase IV (DPP IV) is one of the mechanisms explaining the hypoglycemic effect of berberine

, &
Pages 1061-1066 | Received 14 Jul 2005, Accepted 21 Oct 2008, Published online: 29 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Rohani, Ellin Febrina, Indah Suasani Wahyuni & Jutti Levita. (2023) Pharmacological and Clinical Studies of Medicinal Plants That Inhibit Dipeptidyl Peptidase-IV. Drug Design, Development and Therapy 17, pages 3473-3491.
Read now
Pramod Kumar, Heera Ram, Chandra Kala, Priya Kashyap, Garima Singh, Charu Agnihotri, Bhim Pratap Singh, Ashok Kumar & Anil Panwar. (2023) DPP-4 inhibition mediated antidiabetic potential of phytoconstituents of an aqueous fruit extract of Withania coagulans (Stocks) Dunal: in-silico, in-vitro and in-vivo assessments. Journal of Biomolecular Structure and Dynamics 41:13, pages 6145-6167.
Read now
Idowu Jonas Sagbo, Maryna van de Venter, Trevor Koekemoer & Graeme Bradley. (2022) Exploring the Antidiabetic Mechanism of Brachylaena Ilicifolia Using Target Directed in Vitro Screening. Journal of Herbs, Spices & Medicinal Plants 28:3, pages 309-323.
Read now
Satyender Kumar, Prakash Niguram, Vedika Bhat, Seema Jinagal, Vinod Jairaj & Neelam Chauhan. (2022) Synthesis, molecular docking and ADMET prediction of novel swertiamarin analogues for the restoration of type-2 diabetes: an enzyme inhibition assay. Natural Product Research 36:9, pages 2197-2207.
Read now
Danielle Calderwood, Eamon Rafferty, Ciaran Fitzgerald, Velizara Stoilova, Alastair Wylie, Brendan F. Gilmore, Francisco Castaneda, Alvaro Israel, Christine A. Maggs & Brian D. Green. (2021) Profiling the activity of edible European macroalgae towards pharmacological targets for type 2 diabetes mellitus. Applied Phycology 2:1, pages 10-21.
Read now
P.S. Unnikrishnan, K. Suthindhiran & M.A. Jayasri. (2015) Antidiabetic potential of marine algae by inhibiting key metabolic enzymes. Frontiers in Life Science 8:2, pages 148-159.
Read now
Kimberly A Coughlan, Rudy J Valentine, Neil B Ruderman & Asish K Saha. (2014) AMPK activation: a therapeutic target for type 2 diabetes?. Diabetes, Metabolic Syndrome and Obesity 7, pages 241-253.
Read now

Articles from other publishers (92)

Khurshid Ahmad, Sibhghatulla Shaikh, Jeong Ho Lim, Syed Sayeed Ahmad, Hee Jin Chun, Eun Ju Lee & Inho Choi. (2023) Therapeutic application of natural compounds for skeletal muscle-associated metabolic disorders: A review on diabetes perspective. Biomedicine & Pharmacotherapy 168, pages 115642.
Crossref
P. S. Unnikrishnan, K. Suthindhiran & M. A. Jayasri. (2023) Effect of marine red algal (Portieria hornemannii) extracts on starch digestion rate and its possible role in diabetes management. Aquaculture International 31:6, pages 3239-3256.
Crossref
J. Achyutha Devi, G. Bindu & S. Ravi Kiran. (2023) Evaluation of in vitro glucose metabolism potential of sterols and essential oil extracts from Erythroxylum monogynum Roxb. using cell lines and enzyme inhibition models. South African Journal of Botany 159, pages 110-130.
Crossref
AbdulRahman A. I. Alyahya, Mohammed Asad, Mohammed Alrouji, Kamal Eldin Ahmed Abdelsalam, Adel Mashan Rashed Al-Mutairi & Monjid Ahmed Ibrahim Ahmed. (2023) Hypolipidemic and Antihyperlipidemic Effects of Holarrhena pubescens Methanolic Extract Is Mediated through Inhibition of Lipase Activity and Lipid Accumulation. Life 13:7, pages 1435.
Crossref
Tri Widyawati, Rony Abdi Syahputra, Siti Syarifah & Imam Bagus Sumantri. (2023) Analysis of Antidiabetic Activity of Squalene via In Silico and In Vivo Assay. Molecules 28:9, pages 3783.
Crossref
Indah Purwaningsih, Iman Permana Maksum, Dadan Sumiarsa & Sriwidodo Sriwidodo. (2023) A Review of Fibraurea tinctoria and Its Component, Berberine, as an Antidiabetic and Antioxidant. Molecules 28:3, pages 1294.
Crossref
Ana L. S. Oliveira, Maria João Carvalho, Diana Luazi Oliveira, Eduardo Costa, Manuela Pintado & Ana Raquel Madureira. (2022) Sugarcane Straw Polyphenols as Potential Food and Nutraceutical Ingredient. Foods 11:24, pages 4025.
Crossref
Pullikaparambil Sasidharan Unnikrishnan, Andhere Animish, Gunabalan Madhumitha, Krishnamurthy Suthindhiran & Mangalam Achuthananthan Jayasri. (2022) Bioactivity Guided Study for the Isolation and Identification of Antidiabetic Compounds from Edible Seaweed—Ulva reticulata. Molecules 27:24, pages 8827.
Crossref
Farjana Sharmen, Md. Atiar Rahman, A. M. Abu Ahmed, Tanvir Ahmed Siddique, Md. Khalid Juhani Rafi & Jitbanjong Tangpong. (2022) Upregulation of Antioxidative Gene Expression by Lasia spinosa Organic Extract Improves the Predisposing Biomarkers and Tissue Architectures in Streptozotocin-Induced Diabetic Models of Long Evans Rats. Antioxidants 11:12, pages 2398.
Crossref
Srishti Chhabria, Shivangi Mathur, Sebastian Vadakan, Dipak Kumar Sahoo, Pragnyashree Mishra & Biswaranjan Paital. (2022) A review on phytochemical and pharmacological facets of tropical ethnomedicinal plants as reformed DPP-IV inhibitors to regulate incretin activity. Frontiers in Endocrinology 13.
Crossref
Sanjay Naik, Neha Deora, Sudhir Kumar Pal, Mohammad Z. Ahmed, Ali S. Alqahtani, Prakash Kumar Shukla, Krishnan Venkatraman & Sanjit Kumar. (2022) Purification, biochemical characterization, and DPP‐IV and α ‐amylase inhibitory activity of Berberine from Cardiospermum halicacabum . Journal of Molecular Recognition 35:11.
Crossref
Duyi Samyor, Danielle Calderwood, Manus Carey, Amit B. Das, Brian D. Green & Sankar C. Deka. (2022) Dipeptidyl peptidase-4 (DPP-4) inhibitory activity and glucagon-like peptide (GLP-1) secretion in arsenically safe pigmented red rice (Oryza sativa L.) and its product. Journal of Food Science and Technology 59:10, pages 4016-4024.
Crossref
Tapan Behl, Amit Gupta, Mohammed Albratty, Asim Najmi, Abdulkarim M. Meraya, Hassan A. Alhazmi, Md. Khalid Anwer, Saurabh Bhatia & Simona Gabriela Bungau. (2022) Alkaloidal Phytoconstituents for Diabetes Management: Exploring the Unrevealed Potential. Molecules 27:18, pages 5851.
Crossref
Sarah Jane Monica, Sheila John, R. Madhanagopal, C. Sivaraj, Ameer Khusro, P. Arumugam, Márió Gajdács, D. Esther Lydia, Muhammad Umar Khayam Sahibzada, Saad Alghamdi, Mazen Almehmadi & Talha Bin Emran. (2022) Chemical composition of pumpkin (Cucurbita maxima) seeds and its supplemental effect on Indian women with metabolic syndrome. Arabian Journal of Chemistry 15:8, pages 103985.
Crossref
Arpita Das, J. Naveen, Y. N. Sreerama, B. S. Gnanesh Kumar & V. Baskaran. (2021) Low-glycemic foods with wheat, barley and herbs (Terminalia chebula, Terminalia bellerica and Emblica officinalis) inhibit α-amylase, α-glucosidase and DPP-IV activity in high fat and low dose streptozotocin-induced diabetic rat. Journal of Food Science and Technology 59:6, pages 2177-2188.
Crossref
Wen Xin Janice Lim, Cheryl S. Gammon, Pamela von Hurst, Lynne Chepulis & Rachel A. Page. (2022) The Inhibitory Effects of New Zealand Pine Bark (Enzogenol®) on α-Amylase, α-Glucosidase, and Dipeptidyl Peptidase-4 (DPP-4) Enzymes. Nutrients 14:8, pages 1596.
Crossref
Rachanida Praparatana, Pattaravan Maliyam, Louis R. Barrows & Panupong Puttarak. (2022) Flavonoids and Phenols, the Potential Anti-Diabetic Compounds from Bauhinia strychnifolia Craib. Stem.. Molecules 27:8, pages 2393.
Crossref
Amal Kumar Dhara & Amit Kumar Nayak. 2022. Herbal Biomolecules in Healthcare Applications. Herbal Biomolecules in Healthcare Applications 1 19 .
Biswanath Dinda & Manikarna Dinda. 2022. Natural Products in Obesity and Diabetes. Natural Products in Obesity and Diabetes 101 275 .
Ravinder Singh, Harbir Kaur Rao, Anil Sharma, Thakur Gurjeet Singh, Abhimanyu Parashar, Randhir Singh & Balraj Saini. (2021) Comparative Evaluation of BGR-34 and Sitagliptin in Diabetic Subjects - Open Labelled Randomised Parallel Clinical Study. Serbian Journal of Experimental and Clinical Research 22:4, pages 325-332.
Crossref
Narges Hedayati, Zahra Oskouei, Jamshid Tabeshpour & Mehri Bemani Naeini. (2021) Berberine and lycopene as alternative or add-on therapy to metformin and statins, a review. European Journal of Pharmacology 913, pages 174590.
Crossref
Bikash Adhikari. (2021) Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus. Journal of Chemistry 2021, pages 1-10.
Crossref
Jing Zhang, Xing-Kai Qian, Pei-Fang Song, Xiao-Dong Li, An-Qi Wang, Hong Huo, Jing-Chun Yao, Gui-Min Zhang & Li-Wei Zou. (2021) A high-throughput screening assay for dipeptidyl peptidase-IV inhibitors using human plasma. Analytical Methods 13:24, pages 2671-2678.
Crossref
Sibhghatulla Shaikh, Eun-Ju Lee, Khurshid Ahmad, Syed-Sayeed Ahmad, Jeong-Ho Lim & Inho Choi. (2021) A Comprehensive Review and Perspective on Natural Sources as Dipeptidyl Peptidase-4 Inhibitors for Management of Diabetes. Pharmaceuticals 14:6, pages 591.
Crossref
Mutiu Kazeem, Habeeb Bankole, Olabisi Ogunrinola, Adedoja Wusu & Abidemi Kappo. (2021) Functional foods with dipeptidyl peptidase‐4 inhibitory potential and management of type 2 diabetes: A review. Food Frontiers 2:2, pages 153-162.
Crossref
Heera Ram, Pramod Kumar, Ashok Purohit, Priya Kashyap, Suresh Kumar, Shivani Kumar, Garima Singh, Abdulaziz A. Alqarawi, Abeer Hashem, Elsayed Fathi Abd-Allah, Al-Bandari Fahad Al-Arjani & Bhim Pratap Singh. (2021) Improvements in HOMA indices and pancreatic endocrinal tissues in type 2-diabetic rats by DPP-4 inhibition and antioxidant potential of an ethanol fruit extract of Withania coagulans. Nutrition & Metabolism 18:1.
Crossref
Shafiq Ur Rahman, Hafiz Saqib Ali, Behzad Jafari, Sumera Zaib, Abdul Hameed, Yasser M.S.A Al-Kahraman, Peter Langer & Jamshed Iqbal. (2021) Structure-based virtual screening of dipeptidyl peptidase 4 inhibitors and their in vitro analysis. Computational Biology and Chemistry 91, pages 107326.
Crossref
Rita de Cássia Lemos Lima, Ulrike Böcker, Gordon J. McDougall, J. William Allwood, Nils Kristian Afseth & Sileshi Gizachew Wubshet. (2021) Magnetic ligand fishing using immobilized DPP-IV for identification of antidiabetic ligands in lingonberry extract. PLOS ONE 16:2, pages e0247329.
Crossref
Shahzad Khan, Syed S. Ahmad & Mohammad A. Kamal. (2021) Diabetic Cardiomyopathy: From Mechanism to Management in a Nutshell. Endocrine, Metabolic & Immune Disorders - Drug Targets 21:2, pages 268-281.
Crossref
Xinmei Xu, Huan Yi, Jiasi Wu, Tingting Kuang, Jing Zhang, Qi Li, Huan Du, Tong Xu, Guihua Jiang & Gang Fan. (2021) Therapeutic effect of berberine on metabolic diseases: Both pharmacological data and clinical evidence. Biomedicine & Pharmacotherapy 133, pages 110984.
Crossref
João Soeiro Teodoro, Ivo F. Machado, Ana Catarina Castela, Anabela Pinto Rolo & Carlos Marques Palmeira. 2021. Nutraceuticals. Nutraceuticals 463 483 .
Andrew G. Mtewa, Chukwuebuka Egbuna, Tamirat Bekele Beressa, Kennedy J. Ngwira & Fanuel Lampiao. 2021. Preparation of Phytopharmaceuticals for the Management of Disorders. Preparation of Phytopharmaceuticals for the Management of Disorders 25 38 .
Ankit P. Laddha & Yogesh A. Kulkarni. 2021. Structure and Health Effects of Natural Products on Diabetes Mellitus. Structure and Health Effects of Natural Products on Diabetes Mellitus 235 249 .
L. A. Sulaimon, E. O. Anise, E. M. Obuotor, T. A. Samuel, A. I. Moshood, M. Olajide & T. Fatoke. (2020) In vitro antidiabetic potentials, antioxidant activities and phytochemical profile of african black pepper (Piper guineense). Clinical Phytoscience 6:1.
Crossref
Vishakha Parab Gaonkar & Kirankumar Hullatti. (2020) Indian Traditional medicinal plants as a source of potent Anti-diabetic agents: A Review. Journal of Diabetes & Metabolic Disorders 19:2, pages 1895-1908.
Crossref
Ehsan Dehdashtian, Mohammad Hossein Pourhanifeh, Karim Hemati, Saeed Mehrzadi & Azam Hosseinzadeh. (2020) Therapeutic application of nutraceuticals in diabetic nephropathy: Current evidence and future implications. Diabetes/Metabolism Research and Reviews 36:8.
Crossref
Yuliet, Elin Y. Sukandar & I.K. Adnyana. (2020) Active Subfractions, Phytochemical Constituents, Dipeptidyl Peptidase-IV Inhibitory Activity and Antioxidant of Leaf Extract from Hibiscus surattensis L.. The Natural Products Journal 10:4, pages 400-410.
Crossref
Mojgan Sanjari, Behrang Shamsinejad, Payam Khazaeli, Zohreh Safi, Fatemeh Mirrashidi & Ahmad Naghibzadeh-Tahami. (2020) Safety and efficacy of Berberis integerrima root extract in patients with type 2 diabetes. A parallel intervention based triple blind clinical trial. Journal of Diabetes & Metabolic Disorders 19:1, pages 71-80.
Crossref
Amira R. Amin, Rami B. Kassab, Ahmed E. Abdel Moneim & Hatem K. Amin. (2020) Comparison Among Garlic, Berberine, Resveratrol, Hibiscus sabdariffa , Genus Zizyphus , Hesperidin, Red Beetroot, Catha edulis , Portulaca oleracea , and Mulberry Leaves in the Treatment of Hypertension and Type 2 DM: A Comprehensive Review . Natural Product Communications 15:4, pages 1934578X2092162.
Crossref
Erum Dilshad, Hammad Ismail, Mubarak Ali Khan, Rosa Maria Cusido & Bushra Mirza. (2020) Metabolite profiling of Artemisia carvifolia Buch transgenic plants and estimation of their anticancer and antidiabetic potential. Biocatalysis and Agricultural Biotechnology 24, pages 101539.
Crossref
Youn Hee Nam, Bin Na Hong, Isabel Rodriguez, Min Seon Park, Seo Yule Jeong, Yeong-Geun Lee, Ji Heon Shim, Tamanna Yasmin, Na Woo Kim, Young Tae Koo, Sang Hun Lee, Dong-Hyun Paik, Yong Joon Jeong, Hyelin Jeon, Se Chan Kang, Nam-In Baek & Tong Ho Kang. (2020) Steamed Ginger May Enhance Insulin Secretion through KATP Channel Closure in Pancreatic β-Cells Potentially by Increasing 1-Dehydro-6-Gingerdione Content. Nutrients 12:2, pages 324.
Crossref
Chang-woon Jeung, Sun-woo Jeon, Sin-yeong Jeong & Hee-geun Jo. (2019) Simple Obesity Treatment by Single Intervention of Herbal Medicines without Ephedra Herba: A Case Report. The Journal of Internal Korean Medicine 40:6, pages 1294-1302.
Crossref
Krisyanti Budipramana, Junaidin Junaidin, Komar Ruslan Wirasutisna, Yanatra Budi Pramana & Sukrasno Sukrasno. (2019) An Integrated In Silico and In Vitro Assays of Dipeptidyl Peptidase-4 and α-Glucosidase Inhibition by Stellasterol from Ganoderma australe. Scientia Pharmaceutica 87:3, pages 21.
Crossref
Habib Yaribeygi, Stephen L. Atkin & Amirhossein Sahebkar. (2019) Natural compounds with DPP‐4 inhibitory effects: Implications for the treatment of diabetes. Journal of Cellular Biochemistry 120:7, pages 10909-10913.
Crossref
Ghulam Abbas, Ahmed Al Harrasi, Hidayat Hussain, Ahmed Hamaed & Claudiu T. Supuran. (2019) The management of diabetes mellitus-imperative role of natural products against dipeptidyl peptidase-4, α-glucosidase and sodium-dependent glucose co-transporter 2 (SGLT2). Bioorganic Chemistry 86, pages 305-315.
Crossref
Ipseeta Ray Mohanty, Manjusha Borde, Selvaa Kumar C & Ujwala Maheshwari. (2019) Dipeptidyl peptidase IV Inhibitory activity of Terminalia arjuna attributes to its cardioprotective effects in experimental diabetes: In silico, in vitro and in vivo analyses. Phytomedicine 57, pages 158-165.
Crossref
Jian-Hua He, Li-Xia Chen & Hua Li. (2019) Progress in the discovery of naturally occurring anti-diabetic drugs and in the identification of their molecular targets. Fitoterapia 134, pages 270-289.
Crossref
Rita de Cássia Lemos Lima, Ragnhild Stenberg Berg, Sissel Beate Rønning, Nils Kristian Afseth, Svein Halvor Knutsen, Dan Staerk & Sileshi Gizachew Wubshet. (2019) Peptides from chicken processing by-product inhibit DPP-IV and promote cellular glucose uptake: potential ingredients for T2D management. Food & Function 10:3, pages 1619-1628.
Crossref
Dong‐Hua Mi, Hong‐Juan Fang, Guang‐Hui Zheng, Xian‐Hong Liang, Ya‐Rong Ding, Xin Liu & Li‐Ping Liu. (2018) DPP‐4 inhibitors promote proliferation and migration of rat brain microvascular endothelial cells under hypoxic/high‐glucose conditions, potentially through the SIRT1/HIF‐1/VEGF pathway. CNS Neuroscience & Therapeutics 25:3, pages 323-332.
Crossref
Shian-Ren Lin, Chia-Hsiang Chang, May-Jwan Tsai, Henrich Cheng, Jian-Chyi Chen, Max K. Leong & Ching-Feng Weng. (2019) The perceptions of natural compounds against dipeptidyl peptidase 4 in diabetes: from in silico to in vivo . Therapeutic Advances in Chronic Disease 10, pages 204062231987530.
Crossref
Pooja Rawat, Pawan Kumar Singh & Vipin Kumar. 2019. Natural Bio-active Compounds. Natural Bio-active Compounds 251 274 .
Akinleye Akinrinde, Trevor Koekemoer, Maryna Van De Venter & Graeme Bradley. (2018) In Vitro Investigation of Potential Anti-Diabetic Activity of the Corm Extract of Hypoxis Argentea Harv. Ex Baker. Acta Pharmaceutica 68:4, pages 389-407.
Crossref
Nosheen Akhtar, Laila Jafri, Brian D Green, Saima Kalsoom & Bushra Mirza. (2018) A Multi-Mode Bioactive Agent Isolated From Ficus microcarpa L. Fill. With Therapeutic Potential for Type 2 Diabetes Mellitus. Frontiers in Pharmacology 9.
Crossref
Maria A. Neag, Andrei Mocan, Javier Echeverría, Raluca M. Pop, Corina I. Bocsan, Gianina Crişan & Anca D. Buzoianu. (2018) Berberine: Botanical Occurrence, Traditional Uses, Extraction Methods, and Relevance in Cardiovascular, Metabolic, Hepatic, and Renal Disorders. Frontiers in Pharmacology 9.
Crossref
Idowu Jonas Sagbo, Maryna van de Venter, Trevor Koekemoer & Graeme Bradley. (2018) In Vitro Antidiabetic Activity and Mechanism of Action of Brachylaena elliptica (Thunb.) DC . Evidence-Based Complementary and Alternative Medicine 2018, pages 1-13.
Crossref
Jayapal Naveen & Vallikannan Baskaran. (2017) Antidiabetic plant-derived nutraceuticals: a critical review. European Journal of Nutrition 57:4, pages 1275-1299.
Crossref
Gulmira Turdu, Hongwei Gao, Yingying Jiang & Madina Kabas. (2018) Plant dipeptidyl peptidase-IV inhibitors as antidiabetic agents: a brief review. Future Medicinal Chemistry 10:10, pages 1229-1239.
Crossref
Rajesh Kumar Suman. (2018) Natural dipeptidyl peptidase-4 inhibitor Terminalia arjuna mitigates myocardial infarction co-existing with diabetes in experimental rats. Journal of Diabetes, Metabolic Disorders & Control 5:2, pages 48-56.
Crossref
Sudhanshu Kumar Bharti, Supriya Krishnan, Ashwini Kumar & Awanish Kumar. (2018) Antidiabetic phytoconstituents and their mode of action on metabolic pathways. Therapeutic Advances in Endocrinology and Metabolism 9:3, pages 81-100.
Crossref
M.N. Beidokhti, E.S. Lobbens, P. Rasoavaivo, D. Staerk & A.K. Jäger. (2018) Investigation of medicinal plants from Madagascar against DPP-IV linked to type 2 diabetes. South African Journal of Botany 115, pages 113-119.
Crossref
Verena B. Oliveira, Raquel L.B. Araújo, Thomas Eidenberger & Maria G.L. Brandão. (2018) Chemical composition and inhibitory activities on dipeptidyl peptidase IV and pancreatic lipase of two underutilized species from the Brazilian Savannah: Oxalis cordata A.St.-Hil. and Xylopia aromatica (Lam.) Mart. Food Research International 105, pages 989-995.
Crossref
Gwendolyn Vliegen & Ingrid De Meester. 2018. Immunity and Inflammation in Health and Disease. Immunity and Inflammation in Health and Disease 133 147 .
Shivani Srivastava, Priya Shree & Yamini Bhusan Tripathi. (2017) Active phytochemicals of Pueraria tuberosa for DPP-IV inhibition: in silico and experimental approach. Journal of Diabetes & Metabolic Disorders 16:1.
Crossref
P. S. Unnikrishnan & M. A. Jayasri. (2016) Antidiabetic studies of Chaetomorpha antennina extract using experimental models. Journal of Applied Phycology 29:2, pages 1047-1056.
Crossref
Jiyoung Park & Hyeung-Jin Jang. (2017) Anti-diabetic effects of natural products an overview of therapeutic strategies. Molecular & Cellular Toxicology 13:1, pages 1-20.
Crossref
Gurudeeban Selvaraj, Satyavani Kaliamurthi, Zeynep E. Cakmak & Turgay Cakmak. (2016) Computational screening of dipeptidyl peptidase IV inhibitors from micoroalgal metabolites by pharmacophore modeling and molecular docking. Phycological Research 64:4, pages 291-299.
Crossref
Appian Subramoniam. 2016. Anti-Diabetes Mellitus Plants. Anti-Diabetes Mellitus Plants 301 380 .
Appian Subramoniam. 2016. Plants with Anti-Diabetes Mellitus Properties. Plants with Anti-Diabetes Mellitus Properties 441 567 .
Harsh Panwar, Danielle Calderwood, Irene R. Grant, Sunita Grover & Brian D. Green. (2015) Lactobacilli possess inhibitory activity against dipeptidyl peptidase-4 (DPP-4). Annals of Microbiology 66:1, pages 505-509.
Crossref
Evangelos P. Daskalopoulos, Cécile Dufeys, Luc Bertrand, Christophe Beauloye & Sandrine Horman. (2016) AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation. Journal of Molecular and Cellular Cardiology 91, pages 188-200.
Crossref
João S. Teodoro, Filipe V. Duarte, Anabela P. Rolo & Carlos M. Palmeira. 2016. Nutraceuticals. Nutraceuticals 387 400 .
Sobhi M. Gomha, Taha M. A. Eldebss, Mohamed G. Badrey, Mohamed M. Abdulla & Abdelrahman S. Mayhoub. (2015) Novel 4-Heteroaryl-Antipyrines as DPP-IV Inhibitors. Chemical Biology & Drug Design 86:5, pages 1292-1303.
Crossref
Yao Xian Chin, Phaik Eem Lim, Christine A. Maggs, Siew Moi Phang, Yusrizam Sharifuddin & Brian D. Green. (2014) Anti-diabetic potential of selected Malaysian seaweeds. Journal of Applied Phycology 27:5, pages 2137-2148.
Crossref
L.H. Gu, L.P. Liao, H.J. Hu, S.W. Annie Bligh, C.H. Wang, G.X. Chou & Z.T. Wang. (2015) A thin-layer chromatography-bioautographic method for detecting dipeptidyl peptidase IV inhibitors in plants. Journal of Chromatography A 1411, pages 116-122.
Crossref
Yuanyuan Gao, Yong Zhang, Jianming Zhu, Bo Li, Zhao Li, Weiliang Zhu, Jiye Shi, Qi Jia & Yiming Li. (2015) Recent progress in natural products as DPP-4 inhibitors. Future Medicinal Chemistry 7:8, pages 1079-1089.
Crossref
Christopher E Ekpenyong, Ernest Akpan & Azah Nyoh. (2015) Ethnopharmacology, phytochemistry, and biological activities of Cymbopogon citratus (DC.) Stapf extracts. Chinese Journal of Natural Medicines 13:5, pages 321-337.
Crossref
Ali Zeytünlüoğlu & Figen Zihnioğlu. (2015) Evaluation of some plants for potential dipeptidyl peptidase IV inhibitory effects in vitro. Turkish Journal of Biochemistry 40:3.
Crossref
Rashmi Saini & Sachin L. Badole. 2015. Glucose Intake and Utilization in Pre-Diabetes and Diabetes. Glucose Intake and Utilization in Pre-Diabetes and Diabetes 349 353 .
Eric YarnellKathy Abascal. (2014) Herbs for Diabetes: Update—Part 1. Alternative and Complementary Therapies 20:6, pages 328-333.
Crossref
Samreen Saleem, Laila Jafri, Ihsan ul Haq, Leng Chee Chang, Danielle Calderwood, Brian D Green & Bushra Mirza. (2014) Plants Fagonia cretica L. and Hedera nepalensis K. Koch contain natural compounds with potent dipeptidyl peptidase-4 (DPP-4) inhibitory activity. Journal of Ethnopharmacology 156, pages 26-32.
Crossref
Omprakash Tanwar, Lalima Tanwar, Md. Shaquiquzzaman, Md. Mumtaz Alam & Mymoona Akhter. (2014) Structure based virtual screening of MDPI database: Discovery of structurally diverse and novel DPP-IV inhibitors. Bioorganic & Medicinal Chemistry Letters 24:15, pages 3447-3451.
Crossref
Hui Wang, Wei Mu, Hongcai Shang, Jia Lin & Xiang Lei. (2014) The Antihyperglycemic Effects of Rhizoma Coptidis and Mechanism of Actions: A Review of Systematic Reviews and Pharmacological Research. BioMed Research International 2014, pages 1-10.
Crossref
P. S. Unnikrishnan, K. Suthindhiran & M. A. Jayasri. (2014) Inhibitory Potential of Turbinaria ornata against Key Metabolic Enzymes Linked to Diabetes . BioMed Research International 2014, pages 1-10.
Crossref
Meritxell Teixidó, Esther Zurita, Laura Mendieta, Benjamí Oller‐Salvia, Roger Prades, Teresa Tarragó & Ernest Giralt. (2013) Dual system for the central nervous system targeting and blood‐brain barrier transport of a selective prolyl oligopeptidase inhibitor. Peptide Science 100:6, pages 662-674.
Crossref
Reginald B. Salonga, Shinsuke Hisaka, Jasmin S. Mendoza, Yoshiaki Takaya, Masatake Niwa, Christina A. Binag & Mitsuhiko Nose. (2012) Suppressive effect of the hot-water extract of Ficus pseudopalma Blanco leaves on the postprandial increase in blood glucose level in mice. Journal of Natural Medicines 67:4, pages 725-729.
Crossref
Kok Keong Tan & Kah Hwi Kim. (2013) Alternanthera sessilis Red Ethyl Acetate Fraction Exhibits Antidiabetic Potential on Obese Type 2 Diabetic Rats . Evidence-Based Complementary and Alternative Medicine 2013, pages 1-8.
Crossref
Sudhanshu Kumar Bharti, Supriya Krishnan, Amit Kumar, Kaushal Kishore Rajak, Krishna Murari, Binod Kumar Bharti & Ashok Kumar Gupta. (2013) Antidiabetic activity and molecular docking of fructooligosaccharides produced by Aureobasidium pullulans in poloxamer-407-induced T2DM rats. Food Chemistry 136:2, pages 813-821.
Crossref
. 2013. Principles and Practice of Phytotherapy. Principles and Practice of Phytotherapy 353 961 .
Sudhanshu Kumar Bharti, Supriya Krishnan, Amit Kumar, Kaushal Kishore Rajak, Krishna Murari, Binod Kumar Bharti & Ashok Kumar Gupta. (2012) Antihyperglycemic activity with DPP-IV inhibition of alkaloids from seed extract of Castanospermum australe: Investigation by experimental validation and molecular docking. Phytomedicine 20:1, pages 24-31.
Crossref
Xiao-Wu Chen, Yuan Ming Di, Jian Zhang, Zhi-Wei Zhou, Chun Guang Li & Shu-Feng Zhou. (2012) Interaction of Herbal Compounds with Biological Targets: A Case Study with Berberine. The Scientific World Journal 2012, pages 1-31.
Crossref
Hsiu-Ju Wang & Been-Huang Chiang. (2012) Anti-diabetic effect of a traditional Chinese medicine formula. Food & Function 3:11, pages 1161.
Crossref
Ting Wang, Ning Wang, Hui Song, Xiaonan Xi, JianAn Wang, Aijun Hao & Tiefu Li. (2011) Preparation of an anhydrous reverse micelle delivery system to enhance oral bioavailability and anti-diabetic efficacy of berberine. European Journal of Pharmaceutical Sciences 44:1-2, pages 127-135.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.