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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 24, 2009 - Issue 5
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Research Article

Synthesis, inhibition of NO production and antiproliferative activities of some indole derivatives

Maria Stefania SinicropiUniversity of Calabria, Department of Pharmaceutical Sciences, 87036 Arcavacata di Rende (CS), Italy
,
Anna CarusoUniversity of Calabria, Department of Pharmaceutical Sciences, 87036 Arcavacata di Rende (CS), Italy
,
Filomena ConfortiUniversity of Calabria, Department of Pharmaceutical Sciences, 87036 Arcavacata di Rende (CS), ItalyCorrespondence[email protected]
,
Mariangela MarrelliUniversity of Calabria, Department of Pharmaceutical Sciences, 87036 Arcavacata di Rende (CS), Italy
,
Hussein El KashefUniversité de Caen Basse-Normandie, U.F.R. des Sciences Pharmaceutiques, Centre d’Etudes et de Recherche sur le Médicament de Normandie, UPRES EA-3915 FR CNRS INC3M, 5, rue Vaubénard, 14032 Caen Cedex, France
,
Jean-charles LancelotUniversité de Caen Basse-Normandie, U.F.R. des Sciences Pharmaceutiques, Centre d’Etudes et de Recherche sur le Médicament de Normandie, UPRES EA-3915 FR CNRS INC3M, 5, rue Vaubénard, 14032 Caen Cedex, France
,
Sylvain RaultUniversité de Caen Basse-Normandie, U.F.R. des Sciences Pharmaceutiques, Centre d’Etudes et de Recherche sur le Médicament de Normandie, UPRES EA-3915 FR CNRS INC3M, 5, rue Vaubénard, 14032 Caen Cedex, France
,
Giancarlo A. StattiUniversity of Calabria, Department of Pharmaceutical Sciences, 87036 Arcavacata di Rende (CS), Italy
&
Francesco MenichiniUniversity of Calabria, Department of Pharmaceutical Sciences, 87036 Arcavacata di Rende (CS), Italy
 show all
Pages 1148-1153 | Received 05 Aug 2008, Accepted 07 Dec 2008, Published online: 19 Mar 2009

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Maria Stefania Sinicropi, Domenico Iacopetta, Camillo Rosano, Rosario Randino, Anna Caruso, Carmela Saturnino, Noemi Muià, Jessica Ceramella, Francesco Puoci, Manuela Rodriquez, Pasquale Longo & Maria Rosaria Plutino. (2018) N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 434-444.
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Saeed-Ur-Rehman, Robila Nawaz & Alia Faiz. (2012) Structural Elucidation of Newly Prepared Complexes of 2-Pyrimidin Amine, N-[E-(2,3-dihydro-IH-indol-3-yl) Methylidene] Along With Bioassay and Thermal Studies. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry 42:8, pages 1053-1059.
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Ezhumalai Yamuna, Anthony Yurcho, RobertJ. Sovesky, PeterM. Smith, Matthias Zeller & Karnam Jayarampillai Rajendra Prasad. (2011) Elegant One-Pot Synthesis of Quinolino[2′,3′:7,6]-cyclohept[1,2-b]indole Through Friedländer and Pfitzinger Annulation Reaction. Synthetic Communications 41:22, pages 3351-3366.
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Articles from other publishers (34)

Nan-Sheng Li, Joseph A. Piccirilli & Geoffrey L. Greene. (2023) Reinvestigating the Synthesis and Characterization of Ethyl 3-[5-(2-Ethoxycarbonyl-1-methylvinyloxy)-1-methyl-1 H -indol-3-yl]-but-2-enoate . ACS Omega 8:35, pages 31941-31945.
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Zunyuan Wang, Xiaoyu Li, Youlu Pan, Zhen Ma, Zhengrong Shen & Wenhai Huang. (2023) An unexpected reaction of indole derivatives and EAA catalyzed with InCl3. Molecular Catalysis 540, pages 113065.
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Alessia Catalano, Antonio Rosato, Lara Salvagno, Domenico Iacopetta, Jessica Ceramella, Giuseppe Fracchiolla, Maria Stefania Sinicropi & Carlo Franchini. (2021) Benzothiazole-Containing Analogues of Triclocarban with Potent Antibacterial Activity. Antibiotics 10:7, pages 803.
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Fedora Grande, Anna De Bartolo, Maria Antonietta Occhiuzzi, Anna Caruso, Carmine Rocca, Teresa Pasqua, Alessia Carocci, Vittoria Rago, Tommaso Angelone & Maria Stefania Sinicropi. (2021) Carbazole and Simplified Derivatives: Novel Tools toward β-Adrenergic Receptors Targeting. Applied Sciences 11:12, pages 5486.
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Domenico Iacopetta, Jessica Ceramella, Alessia Catalano, Carmela Saturnino, Maria Grazia Bonomo, Carlo Franchini & Maria Stefania Sinicropi. (2021) Schiff Bases: Interesting Scaffolds with Promising Antitumoral Properties. Applied Sciences 11:4, pages 1877.
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Alessia Catalano, Domenico Iacopetta, Maria Stefania Sinicropi & Carlo Franchini. (2021) Diarylureas as Antitumor Agents. Applied Sciences 11:1, pages 374.
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Majid M. Heravi & Vahideh Zadsirjan. 2021. Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids. Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids 227 294 .
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Anna Caruso, Alexia Barbarossa, Antonio Tassone, Jessica Ceramella, Alessia Carocci, Alessia Catalano, Giovanna Basile, Alessia Fazio, Domenico Iacopetta, Carlo Franchini & Maria Stefania Sinicropi. (2020) Pomegranate: Nutraceutical with Promising Benefits on Human Health. Applied Sciences 10:19, pages 6915.
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Domenico Iacopetta, Camillo Rosano, Marco Sirignano, Annaluisa Mariconda, Jessica Ceramella, Marco Ponassi, Carmela Saturnino, Maria Stefania Sinicropi & Pasquale Longo. (2020) Is the Way to Fight Cancer Paved with Gold? Metal-Based Carbene Complexes with Multiple and Fascinating Biological Features. Pharmaceuticals 13:5, pages 91.
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Jessica Ceramella, Domenico Iacopetta, Alexia Barbarossa, Anna Caruso, Fedora Grande, Maria Grazia Bonomo, Annaluisa Mariconda, Pasquale Longo, Saturnino Carmela & Maria Stefania Sinicropi. (2020) Carbazole Derivatives as Kinase-Targeting Inhibitors for Cancer Treatment. Mini-Reviews in Medicinal Chemistry 20:6, pages 444-465.
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Dawei Li, Bing Zhou & Bei Lv. (2020) Antibacterial Therapeutic Agents Composed of Functional Biological Molecules. Journal of Chemistry 2020, pages 1-13.
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Fabrizio Francomano, Anna Caruso, Alexia Barbarossa, Alessia Fazio, Chiara La Torre, Jessica Ceramella, Rosanna Mallamaci, Carmela Saturnino, Domenico Iacopetta & Maria Stefania Sinicropi. (2019) β-Caryophyllene: A Sesquiterpene with Countless Biological Properties. Applied Sciences 9:24, pages 5420.
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Anna Caruso, Jessica Ceramella, Domenico Iacopetta, Carmela Saturnino, Maria Vittoria Mauro, Rosalinda Bruno, Stefano Aquaro & Maria Stefania Sinicropi. (2019) Carbazole Derivatives as Antiviral Agents: An Overview. Molecules 24:10, pages 1912.
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Tomoki Itoh, Yuusuke Chiba, Shunsuke Kawaguchi, Yuki Koitaya, Yuuma Yoneta, Koji Yamada & Takumi Abe. (2019) Total synthesis of pyrano[3,2- e ]indole alkaloid fontanesine B by a double cyclization strategy . RSC Advances 9:18, pages 10420-10424.
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R. Tundis, D. Iacopetta, M.S. Sinicropi, M. Bonesi, M. Leporini, N.G. Passalacqua, J. Ceramella, F. Menichini & M.R. Loizzo. (2017) Assessment of antioxidant, antitumor and pro-apoptotic effects of Salvia fruticosa Mill. subsp. thomasii (Lacaita) Brullo, Guglielmo, Pavone & Terrasi (Lamiaceae). Food and Chemical Toxicology 106, pages 155-164.
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Domenico Iacopetta, Alessia Carocci, Maria Stefania Sinicropi, Alessia Catalano, Giovanni Lentini, Jessica Ceramella, Rosita Curcio & Maria Cristina Caroleo. (2017) Old Drug Scaffold, New Activity: Thalidomide-Correlated Compounds Exert Different Effects on Breast Cancer Cell Growth and Progression. ChemMedChem 12:5, pages 381-389.
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Cheng Wang, Tao Wang, Limin Huang, Yajing Hou, Wen Lu & Huaizhen He. (2016) Facile synthetic approach for 5-aryl-9-hydroxypyrano [3,2-f] indole-2(8H)-one. Arabian Journal of Chemistry 9:6, pages 882-890.
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George N. Karageorge & John E. Macor. (2011) Synthesis of dihydropyrano[3,2-e]indoles as rotationally restricted phenolic analogs of 5-hydroxyindole—thermal Claisen approach versus gold catalysis. Tetrahedron Letters 52:9, pages 1011-1013.
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Minoru Ishikura, Koji Yamada, Sayaka Yamaguchi, Noriyuki Hatae, Takumi Abe & Tatsunori Iwamura. (2011) Facile Synthesis of Pyrano[3,2-e]indoles via the Base-Promoted Pictet-Spengler Reaction of Nb-Benzylserotonin. HETEROCYCLES 83:4, pages 815.
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