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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 38, 2023 - Issue 1
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Research Paper

1,2,3-Benzoxathiazine-2,2-dioxides – effective inhibitors of human carbonic anhydrases

Jekaterina Ivanovaa Latvian Institute of Organic Synthesis, Riga, LatviaORCID Iconhttps://orcid.org/0000-0001-8845-0193View further author information
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Morteza Abdolib Faculty of Materials Science and Applied Chemistry, Institute of Technology of Organic Chemistry, Riga Technical University, Riga, LatviaORCID Iconhttps://orcid.org/0000-0003-1647-4262View further author information
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Alessio Nocentinic Neurofarba Department, Università degli Studi di Firenze, Florence, ItalyORCID Iconhttps://orcid.org/0000-0003-3342-702XView further author information
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Raivis Žalubovskisa Latvian Institute of Organic Synthesis, Riga, Latvia;b Faculty of Materials Science and Applied Chemistry, Institute of Technology of Organic Chemistry, Riga Technical University, Riga, LatviaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9471-1342View further author information
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Claudiu T. Supuranc Neurofarba Department, Università degli Studi di Firenze, Florence, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-4262-0323View further author information
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Pages 225-238 | Received 05 Oct 2022, Accepted 28 Oct 2022, Published online: 13 Nov 2022

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Jekaterīna Ivanova, Morteza Abdoli, Alessio Nocentini, Raivis Žalubovskis & Claudiu T. Supuran. (2023) Derivatives of 4-methyl-1,2,3-benzoxathiazine 2,2-dioxide as selective inhibitors of human carbonic anhydrases IX and XII over the cytosolic isoforms I and II. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Morteza Abdoli, Viviana De Luca, Clemente Capasso, Claudiu T. Supuran & Raivis Žalubovskis. (2023) Novel thiazolone-benzenesulphonamide inhibitors of human and bacterial carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Claudiu T Supuran. (2023) Targeting carbonic anhydrases for the management of hypoxic metastatic tumors. Expert Opinion on Therapeutic Patents 33:11, pages 701-720.
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Morteza Abdoli, Viviana De Luca, Clemente Capasso, Claudiu T Supuran & Raivis Žalubovskis. (2023) Investigation of Carbonic Anhydrase Inhibitory Potency of (Z/E)-alkyl N‘-benzyl-N-(arylsulfonyl)-carbamimidothioates. Future Medicinal Chemistry 15:7, pages 615-627.
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Articles from other publishers (9)

Marjan Sobati, Morteza Abdoli, Andrea Angeli, Alessandro Bonardi, Marta Ferraroni, Claudiu T. Supuran & Raivis Žalubovskis. (2024) Sulfonamide‐incorporated bis(α‐aminophosphonates) as promising carbonic anhydrase inhibitors: Design, synthesis, biological evaluation, and X‐ray crystallographic studies. Archiv der Pharmazie.
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Shanshan Wu, Xiaoping Zhou, Fei Li, Wei Sun, Qingchuan Zheng & Di Liang. (2024) Novel Anthraquinone-Based Benzenesulfonamide Derivatives and Their Analogues as Potent Human Carbonic Anhydrase Inhibitors with Antitumor Activity: Synthesis, Biological Evaluation, and In Silico Analysis. International Journal of Molecular Sciences 25:6, pages 3348.
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Gönül Yapar, Nebih Lolak, Alessandro Bonardi, Suleyman Akocak & Claudiu T. Supuran. (2024) Exploring the potency of diazo‐coumarin containing hybrid molecules: Selective inhibition of tumor‐associated carbonic anhydrase isoforms IX and XII. ChemMedChem 19:4.
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Claudiu T. Supuran. (2023) A simple yet multifaceted 90 years old, evergreen enzyme: Carbonic anhydrase, its inhibition and activation. Bioorganic & Medicinal Chemistry Letters 93, pages 129411.
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Marjan Sobati, Morteza Abdoli, Alessandro Bonardi, Paola Gratteri, Claudiu T. Supuran & Raivis Žalubovskis. (2023) Inhibition Profiles of Some Novel Sulfonamide-Incorporated α-Aminophosphonates on Human Carbonic Anhydrases. ACS Medicinal Chemistry Letters 14:8, pages 1067-1072.
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Narges Hosseini Nasab, Hussain Raza, Young Seok Eom, Mubashir Hassan, Andrzej Kloczkowski, Lloyd Christopher Chetty, Hendrik Gert Kruger & Song Ja Kim. (2023) Design, synthesis, and in vitro and in silico studies of 1,3,4-thiadiazole-thiazolidinone hybrids as carbonic anhydrase inhibitors . New Journal of Chemistry 47:29, pages 13710-13720.
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Morteza Abdoli, Alessandro Bonardi, Niccolò Paoletti, Ashok Aspatwar, Seppo Parkkila, Paola Gratteri, Claudiu T. Supuran & Raivis Žalubovskis. (2023) Inhibition Studies on Human and Mycobacterial Carbonic Anhydrases with N-((4-Sulfamoylphenyl)carbamothioyl) Amides. Molecules 28:10, pages 4020.
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Jekateri̅na Ivanova, Alessio Nocentini, Kaspars Ta̅rs, Ja̅nis Leita̅ns, Elviss Dvinskis, Andris Kazaks, Ilona Domračeva, Claudiu T. Supuran & Raivis Žalubovskis. (2023) Atropo/Tropo Flexibility: A Tool for Design and Synthesis of Self-Adaptable Inhibitors of Carbonic Anhydrases and Their Antiproliferative Effect. Journal of Medicinal Chemistry 66:8, pages 5703-5718.
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Morteza Abdoli, Viviana De Luca, Clemente Capasso, Claudiu T. Supuran & Raivis Žalubovskis. (2023) Inhibition Studies on Carbonic Anhydrase Isoforms I, II, IX, and XII with a Series of Sulfaguanidines. ChemMedChem 18:6.
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