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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 38, 2023 - Issue 1
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Research Paper

Design, synthesis, docking, and anticancer evaluations of new thiazolo[3,2-a] pyrimidines as topoisomerase II inhibitors

Mona S. El-Zoghbia Department of Pharmaceutical Chemistry, Menoufia University, Menoufia, EgyptCorrespondence[email protected]
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,
Samiha A. El-Sebaeyb Department of Pharmaceutical Organic Chemistry, Al-Azhar University, Nasr City, Cairo, EgyptCorrespondence[email protected]
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,
Hanan A. AL-Ghulikahc Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaView further author information
&
Eman A. Sobha Department of Pharmaceutical Chemistry, Menoufia University, Menoufia, EgyptView further author information
Article: 2175209 | Received 03 Nov 2022, Accepted 27 Jan 2023, Published online: 12 Feb 2023

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Samar El-Kalyoubi, Samiha A. El-Sebaey, Ahmed A. El-Sayed, Moustafa S. Abdelhamid, Fatimah Agili & Sherin M. Elfeky. (2023) Novel pyrimidine Schiff bases and their selenium-containing nanoparticles as dual inhibitors of CDK1 and tubulin polymerase: design, synthesis, anti-proliferative evaluation, and molecular modelling. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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