Advanced search
Publication Cover
Journal of Enzyme Inhibition and Medicinal Chemistry Volume 38, 2023 - Issue 1
Submit an article Journal homepage
2,785
Views
12
CrossRef citations to date
0
Altmetric
Research Paper

Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer’s disease

Donia E. Hafeza Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, EgyptView further author information
,
Mariam Dubielb Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf, GermanyView further author information
,
Gabriella La Spadac Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Bari, ItalyView further author information
,
Marco Cattoc Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Bari, ItalyView further author information
,
David Reiner-Linkb Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf, GermanyView further author information
,
Yu-Ting Syud Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan, TaiwanView further author information
,
Mohammad Abdel-Halima Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, EgyptCorrespondence[email protected]
View further author information
,
Tsong-Long Hwangd Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan, Taiwan;e Research Center for Chinese Herbal Medicine, Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan, Taiwan;f Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan;g Department of Chemical Engineering, Ming Chi University of Technology, New Taipei City, TaiwanCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5780-3977View further author information
ORCID Icon,
Holger Starkb Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf, GermanyView further author information
&
Ashraf H. Abadia Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, EgyptCorrespondence[email protected]
View further author information
 show all
Article: 2175821 | Received 10 Dec 2022, Accepted 29 Jan 2023, Published online: 15 Feb 2023

Citations (12)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Juan D. Sánchez, Andrés R. Alcántara, Juan F. González & José María Sánchez-Montero. (2023) Advances in the discovery of heterocyclic-based drugs against Alzheimer’s disease. Expert Opinion on Drug Discovery 18:12, pages 1413-1428.
Read now

Articles from other publishers (11)

Yasaman Tamaddon-Abibigloo, Siavoush Dastmalchi, Nima Razzaghi-Asl & Javid Shahbazi Mojarrad. (2024) Design, synthesis, in vitro and in silico evaluations of new isatin-triazine- aniline hybrids as potent anti- Alzheimer multi-target directed lead compounds. Bioorganic Chemistry 147, pages 107355.
Crossref
Nguyen Dinh Thanh, Do Son Hai, Vu Ngoc Toan, Hoang Thi Kim Van, Nguyen Thi Kim Giang & Nguyen Minh Tri. (2024) Sulfonyl thioureas with a benzo[ d ]thiazole ring as dual acetylcholinesterase/butyrylcholinesterase and human monoamine oxidase A and B inhibitors: An in vitro and in silico study . Archiv der Pharmazie 357:5.
Crossref
Soumajit Nath, Sudip Baguli & Debabrata Mukherjee. (2024) A Hybrid Benzothiazolyl-NHC Ligand with a Flexible −CH 2 – Linker and Its Cationic Rh (I) Complex That Catalyzes the Olefin Hydrosilylation . Organometallics.
Crossref
Zuting Ye, Yanming Liu, Xingjiang Jin, Yiqing Wu, Hang Zhao, Tingting Gao, Qiangfeng Deng, Jianhua Cheng, Jing Lin & Zhiqian Tong. (2024) Aβ-binding with alcohol dehydrogenase drives Alzheimer's disease pathogenesis: A review. International Journal of Biological Macromolecules 264, pages 130580.
Crossref
Omar M. Al-Saad, Moustafa Gabr, Sarah S. Darwish, Mariagrazia Rullo, Leonardo Pisani, Daniela Valeria Miniero, Grazia Maria Liuzzi, Andreas M. Kany, Anna K.H. Hirsch, Ashraf H. Abadi, Matthias Engel, Marco Catto & Mohammad Abdel-Halim. (2024) Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity. European Journal of Medicinal Chemistry 269, pages 116266.
Crossref
Chandni Pathak & Uma D. Kabra. (2024) A comprehensive review of multi-target directed ligands in the treatment of Alzheimer’s disease. Bioorganic Chemistry 144, pages 107152.
Crossref
Nguyen Dinh Thanh, Do Son Hai, Nguyen Thi Kim Giang, Vu Ngoc Toan, Hoang Thi Kim Van, Nguyen Minh Tri & Duong Ngoc Toan. (2023) Synthesis, antimicrobial activity and molecular simulation of thiourea derivatives containing 6-carboalkoxybenzo[ d ]thiazole and d -glucose moieties . New Journal of Chemistry 47:48, pages 22360-22376.
Crossref
Eida S. Al‐Farraj & Ahmed Fetoh. (2023) Synthesis of new Fe(III), Co(II), and Cr(III) complexes of N ‐(benzo[ d ]thiazol‐2‐ylcarbamothioyl)benzamide (H 2 L 2 ): Structural characterization and biological activities . Applied Organometallic Chemistry 37:11.
Crossref
Sukriti Srivastava, Shilpa Sharma, Shashank Deep & Sunil Kumar Khare. (2023) Screening of Multitarget-Directed Natural Compounds as Drug Candidates for Alzheimer’s Disease Using In Silico Techniques: Their Extraction and In Vitro Validation . ACS Omega 8:41, pages 38118-38129.
Crossref
Swati Pant, Mohan Gupta, Tulika Anthwal, Monika Chauhan & Sumitra Nain. (2023) Neuroprotective effects of novel pyrrolidine-2-one derivatives on scopolamine-induced cognitive impairment in mice: Behavioral and biochemical analysis. Pharmacology Biochemistry and Behavior 229, pages 173602.
Crossref
Maria A. Tikhonova, Hung-Ming Chang & Sandeep Kumar Singh. (2023) Editorial: Experimental and innovative approaches to multi-target treatment of Parkinson's and Alzheimer's diseases - Volume II. Frontiers in Neuroscience 17.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.