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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 38, 2023 - Issue 1
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Research Article

Design, synthesis, apoptotic, and antiproliferative effects of 5-chloro-3- (2-methoxyvinyl)-indole-2-carboxamides and pyrido[3,4-b]indol-1-ones as potent EGFRWT/EGFRT790M inhibitors

Lamya H. Al-Wahaibia Department of Chemistry, College of Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaCorrespondence[email protected]
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,
Anber F. Mohammedb Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, EgyptView further author information
,
Fatema El-Zahraa S. Abdel Rahmanc Department of Basic Sciences, Faculty of Oral and Dental Medicine, Nahda University, Beni-Suef, EgyptView further author information
,
Mostafa H. Abdelrahmand Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Assiut, EgyptView further author information
,
Xuyuan Gue School of Natural and Computing Sciences, University of Aberdeen, Aberdeen, UKView further author information
,
Laurent Trembleaue School of Natural and Computing Sciences, University of Aberdeen, Aberdeen, UKCorrespondence[email protected]
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Bahaa G. M. Youssifb Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, EgyptCorrespondence[email protected] [email protected]
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Article: 2218602 | Received 21 Dec 2022, Accepted 22 May 2023, Published online: 31 May 2023

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Mohamed A. Mahmoud, Anber F. Mohammed, Ola I. A. Salem, Tahani Mazyad Almutairi, Stefan Bräse & Bahaa G. M. Youssif. (2024) Design, synthesis, and apoptotic antiproliferative action of new 1,2,3-triazole/1,2,4-oxadiazole hybrids as dual EGFR/VEGFR-2 inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 39:1.
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Articles from other publishers (3)

Juan Zhang, Xuliang Liu, Na Sa, Jin-He Zhang, Yong-Si Cai, Kai-Ming Wang, Wei Xu, Cheng-Shi Jiang & Kong-Kai Zhu. (2024) Synthesis and biological evaluation of 1-phenyl-tetrahydro-β-carboline-based first dual PRMT5/EGFR inhibitors as potential anticancer agents. European Journal of Medicinal Chemistry 269, pages 116341.
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Aliaa  M. Mohassab, Heba  A. Hassan, Hesham  A. Abou-Zied, Mikako Fujita, Masami Otsuka, Hesham  A.  M. Gomaa, Bahaa  G.  M. Youssif & Mohamed Abdel-Aziz. (2024) Design and synthesis of new quinoline-ester/-amide derivatives as potent antiproliferative agent targeting EGFR and BRAFV600E kinases. Journal of Molecular Structure 1297, pages 136953.
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Lamya H. Al-Wahaibi, Hesham A. Abou-Zied, Mohamed Hisham, Eman A. M. Beshr, Bahaa G. M. Youssif, Stefan Bräse, Alaa M. Hayallah & Mohamed Abdel-Aziz. (2023) Design, Synthesis, and Biological Evaluation of Novel 3-Cyanopyridone/Pyrazoline Hybrids as Potential Apoptotic Antiproliferative Agents Targeting EGFR/BRAFV600E Inhibitory Pathways. Molecules 28:18, pages 6586.
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