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REVIEW ARTICLE

Pulmonary Hypertension in COPD: A Review and Consideration of the Role of Arterial Vasodilators

Pages 137-144 | Published online: 02 Jul 2009

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Polliana B Dos Santos, Rodrigo P Simões, Cássia da L Goulart, Meliza G Roscani, Renan S Marinho, Patrícia Faria Camargo, Renata F Arbex, Guilherme Casale, Cláudio R Oliveira, Renata G Mendes, Ross Arena & Audrey Borghi-Silva. (2021) Eccentric Left Ventricular Hypertrophy and Left and Right Cardiac Function in Chronic Heart Failure with or without Coexisting COPD: Impact on Exercise Performance. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 203-214.
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Peter Lange, David M Halpin, Denis E O’Donnell & William MacNee. (2016) Diagnosis, assessment, and phenotyping of COPD: beyond FEV1. International Journal of Chronic Obstructive Pulmonary Disease 11:sup1, pages 3-12.
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Annabelle Couillard, Jean François Muir & Daniel Veale. (2010) COPD Recent Findings: Impact on Clinical Practice. COPD: Journal of Chronic Obstructive Pulmonary Disease 7:3, pages 204-213.
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Ratoe Suraya, Tatsuya Nagano, Gusty Rizky Teguh Ryanto, Wiwin Is Effendi, Daisuke Hazama, Naoko Katsurada, Masatsugu Yamamoto, Motoko Tachihara, Noriaki Emoto, Yoshihiro Nishimura & Kazuyuki Kobayashi. (2022) Budesonide/glycopyrronium/formoterol fumarate triple therapy prevents pulmonary hypertension in a COPD mouse model via NFκB inactivation. Respiratory Research 23:1.
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Helen Christou & Raouf A. Khalil. (2022) Mechanisms of pulmonary vascular dysfunction in pulmonary hypertension and implications for novel therapies. American Journal of Physiology-Heart and Circulatory Physiology 322:5, pages H702-H724.
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Helen Christou, Zoe Michael, Fotios Spyropoulos, Yunfei Chen, Dan Rong & Raouf A. Khalil. (2021) Carbonic anhydrase inhibition improves pulmonary artery reactivity and nitric oxide-mediated relaxation in sugen-hypoxia model of pulmonary hypertension. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 320:6, pages R835-R850.
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Marija Gredic, Isabel Blanco, Gabor Kovacs, Zsuzsanna Helyes, Péter Ferdinandy, Horst Olschewski, Joan Albert Barberà & Norbert Weissmann. (2020) Pulmonary hypertension in chronic obstructive pulmonary disease. British Journal of Pharmacology 178:1, pages 132-151.
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Janos Varga, Attila Palinkas, Imre Lajko, Ildikó Horváth, Krisztina Boda & Attila Somfay. (2016) Pulmonary Arterial Pressure Response During Exercise in COPD: A Correlation with C-Reactive Protein (hsCRP). The Open Respiratory Medicine Journal 10:1, pages 1-11.
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Ellen Hillegass, Ann Fick, Amy Pawlik, Rebecca Crouch, Christiane Perme, Rohini Chandrashekar, Susan Butler McNamara & Lawrence P. Cahalin. (2014) Supplemental Oxygen Utilization During Physical Therapy Interventions. Cardiopulmonary Physical Therapy Journal 25:2, pages 38-49.
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Wim Timens, Hannie Sietsma & Joanne L. Wright. 2014. Spencer's Pathology of the Lung. Spencer's Pathology of the Lung 605 660 .
Robert P. Frantz & Michael D. McGoon. (2012) Diagnostic Dilemmas in Pulmonary Hypertension. Heart Failure Clinics 8:3, pages 331-352.
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Helen Christou, Ossama M. Reslan, Virak Mam, Alain F. Tanbe, Sally H. Vitali, Marlin Touma, Elena Arons, S. Alex Mitsialis, Stella Kourembanas & Raouf A. Khalil. (2012) Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension. American Journal of Physiology-Lung Cellular and Molecular Physiology 302:9, pages L875-L890.
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Mitra Esfandiarei, Julia T. N. Lam, Sahar Abdoli Yazdi, Amina Kariminia, Jorge Navarro Dorado, Boris Kuzeljevic, Harley T. Syyong, Kaiji Hu & Cornelis van Breemen. (2011) Diosgenin Modulates Vascular Smooth Muscle Cell Function by Regulating Cell Viability, Migration, and Calcium Homeostasis. Journal of Pharmacology and Experimental Therapeutics 336:3, pages 925-939.
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Neal M. Patel & Charles D. Burger. (2011) Two cases of stem cell therapy for pulmonary hypertension: A clinical report. Respiratory Medicine CME 4:2, pages 70-74.
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C. Gregory Elliott, Robyn J. Barst, Werner Seeger, Mateo Porres-Aguilar, Lynette M. Brown, Roham T. Zamanian & Lewis J. Rubin. (2010) Worldwide Physician Education and Training in Pulmonary Hypertension. Chest 137:6, pages 85S-94S.
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Jonathan De Blois, Serge Simard, Dan Atar & Stefan Agewall. (2010) COPD Predicts Mortality in HF: The Norwegian Heart Failure Registry. Journal of Cardiac Failure 16:3, pages 225-229.
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V. Mam, A. F. Tanbe, S. H. Vitali, E. Arons, H. A. Christou & R. A. Khalil. (2009) Impaired Vasoconstriction and Nitric Oxide-Mediated Relaxation in Pulmonary Arteries of Hypoxia- and Monocrotaline-Induced Pulmonary Hypertensive Rats. Journal of Pharmacology and Experimental Therapeutics 332:2, pages 455-462.
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