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Cell Communication & Adhesion Volume 15, 2008 - Issue 1-2
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Original

Diverse Subcellular Distribution Profiles of Pannexin1 and Pannexin3

Silvia Penuela Departments of Anatomy and Cell Biology, University of Western Ontario, London, Ontario, Canada
,
Steven J. Celetti Departments of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada
,
Ruchi Bhalla Departments of Anatomy and Cell Biology, University of Western Ontario, London, Ontario, Canada
,
Qing Shao Departments of Anatomy and Cell Biology, University of Western Ontario, London, Ontario, Canada
&
Dale W. Laird Departments of Anatomy and Cell Biology, University of Western Ontario, London, Ontario, Canada
Pages 133-142 | Received 22 Oct 2007, Accepted 07 Dec 2007, Published online: 11 Jul 2009

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Helen P Makarenkova, Sameer B Shah & Valery I Shestopalov. (2018) The two faces of pannexins: new roles in inflammation and repair. Journal of Inflammation Research 11, pages 273-288.
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Rachael Bartlett, Leanne Stokes, Stephen J. Curtis, Belinda L. Curtis & Ronald Sluyter. (2017) Probenecid directly impairs activation of the canine P2X7 receptor. Nucleosides, Nucleotides & Nucleic Acids 36:12, pages 736-744.
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Kenji F Shoji, Pablo J Sáez, Paloma A Harcha, Hector L Aguila & Juan C Sáez. (2014) Pannexin1 channels act downstream of P2X7 receptors in ATP-induced murine T-cell death. Channels 8:2, pages 142-156.
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Andrew KJ Boyce, Ross T Prager, Leigh E Wicki-Stordeur & Leigh Anne Swayne. (2014) Pore positioning. Channels 8:2, pages 110-117.
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Articles from other publishers (56)

Hang Zhang, Shiyu Wang, Zhenzhen Zhang, Mengzhuo Hou, Chunyu Du, Zhenye Zhao, Horst Vogel, Zhifang Li, Kaige Yan, Xiaokang Zhang, Jianping Lu, Yujie Liang, Shuguang Yuan, Daping Wang & Huawei Zhang. (2023) Cryo-EM structure of human heptameric pannexin 2 channel. Nature Communications 14:1.
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Olga M. Rusiecka, Malaury Tournier, Filippo Molica & Brenda R. Kwak. (2022) Pannexin1 channels—a potential therapeutic target in inflammation. Frontiers in Cell and Developmental Biology 10.
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Amir Tajbakhsh, Fatemeh Yousefi, Seyedeh M. Abedi, Mehdi Rezaee, Amir Savardashtaki, Yong Teng & Amirhossein Sahebkar. (2022) The cross‐talk between soluble “Find me” and “Keep out” signals as an initial step in regulating efferocytosis. Journal of Cellular Physiology 237:8, pages 3113-3126.
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Eijaz Ahmed Bhat & Nasreena Sajjad. (2021) Human Pannexin 1 channel: Insight in structure–function mechanism and its potential physiological roles. Molecular and Cellular Biochemistry 476:3, pages 1529-1540.
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Zheng Ruan, Ian J. Orozco, Juan Du & Wei Lü. (2020) Structures of human pannexin 1 reveal ion pathways and mechanism of gating. Nature 584:7822, pages 646-651.
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Yang Yang, Leon J. Delalio, Angela K. Best, Edgar Macal, Jenna Milstein, Iona Donnelly, Ashley M. Miller, Martin McBride, Xiaohong Shu, Michael Koval, Brant E. Isakson & Scott R. Johnstone. (2020) Endothelial Pannexin 1 Channels Control Inflammation by Regulating Intracellular Calcium. The Journal of Immunology 204:11, pages 2995-3007.
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Masaki Ishikawa, Geneva Williams, Patricia Forcinito, Momoko Ishikawa, Ryan J. Petrie, Kan Saito, Satoshi Fukumoto & Yoshihiko Yamada. (2019) Pannexin 3 ER Ca2+ channel gating is regulated by phosphorylation at the Serine 68 residue in osteoblast differentiation. Scientific Reports 9:1.
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Mireille Alhouayek, René Sorti, Jonathan D. Gilthorpe & Christopher J. Fowler. (2019) Role of pannexin-1 in the cellular uptake, release and hydrolysis of anandamide by T84 colon cancer cells. Scientific Reports 9:1.
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Mark S. Aquilino, Paige Whyte-Fagundes, Georg Zoidl & Peter L. Carlen. (2019) Pannexin-1 channels in epilepsy. Neuroscience Letters 695, pages 71-75.
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Eliana Scemes & Jana Velíšková. (2019) Exciting and not so exciting roles of pannexins. Neuroscience Letters 695, pages 25-31.
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Vanessa R. Lee, Kevin J. Barr, John J. Kelly, Danielle Johnston, Cody F. C. Brown, Kevin P. Robb, Samar Sayedyahossein, Kenneth Huang, Robert Gros, Lauren E. Flynn & Silvia Penuela. (2018) Pannexin 1 regulates adipose stromal cell differentiation and fat accumulation. Scientific Reports 8:1.
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Rafael Sanchez-Pupo, Danielle Johnston & Silvia Penuela. (2018) N-Glycosylation Regulates Pannexin 2 Localization but Is Not Required for Interacting with Pannexin 1. International Journal of Molecular Sciences 19:7, pages 1837.
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Jonathan Boucher, Claire Simonneau, Golthlay Denet, Jonathan Clarhaut, Annie-Claire Balandre, Marc Mesnil, Laurent Cronier & Arnaud Monvoisin. (2018) Pannexin-1 in Human Lymphatic Endothelial Cells Regulates Lymphangiogenesis. International Journal of Molecular Sciences 19:6, pages 1558.
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Marc Chanson, Masakatsu Watanabe, Erin O’Shaughnessy, Alice Zoso & Patricia Martin. (2018) Connexin Communication Compartments and Wound Repair in Epithelial Tissue. International Journal of Molecular Sciences 19:5, pages 1354.
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Paige Whyte-Fagundes, Stefan Kurtenbach, Christiane Zoidl, Valery I. Shestopalov, Peter L. Carlen & Georg Zoidl. (2018) A Potential Compensatory Role of Panx3 in the VNO of a Panx1 Knock Out Mouse Model. Frontiers in Molecular Neuroscience 11.
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Julien Guerrero, Hugo Oliveira, Rachida Aid, Reine Bareille, Robin Siadous, Didier Letourneur, Yong Mao, Joachim Kohn & Joëlle Amédée. (2018) Influence of the three‐dimensional culture of human bone marrow mesenchymal stromal cells within a macroporous polysaccharides scaffold on Pannexin 1 and Pannexin 3. Journal of Tissue Engineering and Regenerative Medicine 12:4, pages e1936-e1949.
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Akiyuki Taruno. (2018) ATP Release Channels. International Journal of Molecular Sciences 19:3, pages 808.
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Shenglong Li, Jing Wang, Yudi Han, Xiaoteng Li, Changjian Liu, Zhengshuai Lv, Xiuhui Wang, Xin Tang & Zhe Wang. (2018) Carbenoxolone inhibits mechanical stress-induced osteogenic differentiation of mesenchymal stem cells by regulating p38 MAPK phosphorylation. Experimental and Therapeutic Medicine.
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Yu-Hsin Chiu, Michael S. Schappe, Bimal N. Desai & Douglas A. Bayliss. (2018) Revisiting multimodal activation and channel properties of Pannexin 1. Journal of General Physiology 150:1, pages 19-39.
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Paige Whyte-Fagundes & Georg Zoidl. (2018) Mechanisms of pannexin1 channel gating and regulation. Biochimica et Biophysica Acta (BBA) - Biomembranes 1860:1, pages 65-71.
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Andrew K.J. Boyce, Anna L. Epp, Archana Nagarajan & Leigh Anne Swayne. (2018) Transcriptional and post-translational regulation of pannexins. Biochimica et Biophysica Acta (BBA) - Biomembranes 1860:1, pages 72-82.
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Lilian I. Plotkin, Dale W. Laird & Joelle Amedee. (2016) Role of connexins and pannexins during ontogeny, regeneration, and pathologies of bone. BMC Cell Biology 17:S1.
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Jessica L. Esseltine & Dale W. Laird. (2016) Next-Generation Connexin and Pannexin Cell Biology. Trends in Cell Biology 26:12, pages 944-955.
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Qing Shao, Kristin Lindstrom, Ruoyang Shi, John Kelly, Audrey Schroeder, Jane Juusola, Kara L. Levine, Jessica L. Esseltine, Silvia Penuela, Michael F. Jackson & Dale W. Laird. (2016) A Germline Variant in the PANX1 Gene Has Reduced Channel Function and Is Associated with Multisystem Dysfunction. Journal of Biological Chemistry 291:24, pages 12432-12443.
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Bruno Cogliati, Gregory Mennecier, Joost Willebrords, Tereza Cristina Da Silva, Michaël Maes, Isabel Veloso Alves Pereira, Sara Crespo Yanguas, Francisco Javier Hernandez-Blazquez, Maria Lúcia Zaidan Dagli & Mathieu Vinken. (2016) Connexins, Pannexins, and Their Channels in Fibroproliferative Diseases. The Journal of Membrane Biology 249:3, pages 199-213.
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Deidre Caskenette, Silvia Penuela, Vanessa Lee, Kevin Barr, Frank Beier, Dale W. Laird & Katherine E. Willmore. (2016) Global deletion of Panx3 produces multiple phenotypic effects in mouse humeri and femora . Journal of Anatomy 228:5, pages 746-756.
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Tina M. Kringelbach, Derya Aslan, Ivana Novak, Maria Ellegaard, Susanne Syberg, Christina K.B. Andersen, Kim A. Kristiansen, Ole Vang, Peter Schwarz & Niklas R. Jørgensen. (2015) Fine-tuned ATP signals are acute mediators in osteocyte mechanotransduction. Cellular Signalling 27:12, pages 2401-2409.
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Andrew K.J. Boyce, Michelle S. Kim, Leigh E. Wicki-Stordeur & Leigh Anne Swayne. (2015) ATP stimulates pannexin 1 internalization to endosomal compartments. Biochemical Journal 470:3, pages 319-330.
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Julie Dufresne & Daniel G. Cyr. (2014) Regulation of the Pannexin-1 Promoter in the Rat Epididymis1. Biology of Reproduction 91:6.
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Fanny Momboisse, María José Olivares, Ximena Báez-Matus, María José Guerra, Carolina Flores-Muñoz, Juan C. Sáez, Agustín D. Martínez & Ana M. Cárdenas. (2014) Pannexin 1 channels: new actors in the regulation of catecholamine release from adrenal chromaffin cells. Frontiers in Cellular Neuroscience 8.
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Tae-Jun Kwon, Dong-Bin Kim, Jae Woong Bae, Borum Sagong, Soo-Young Choi, Hyun-Ju Cho, Un-Kyung Kim & Kyu-Yup Lee. (2014) Molecular cloning, characterization, and expression of pannexin genes in chicken. Poultry Science 93:9, pages 2253-2261.
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Silvia Penuela, Luke Harland, Jamie Simek & Dale W. Laird. (2014) Pannexin channels and their links to human disease. Biochemical Journal 461:3, pages 371-381.
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Silvia Penuela, Jamie Simek & Roger J. Thompson. (2014) Regulation of pannexin channels by post-translational modifications. FEBS Letters 588:8, pages 1411-1415.
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Catheleyne D'hondt, Jegan Iyyathurai, Mathieu Vinken, Vera Rogiers, Luc Leybaert, Bernard Himpens & Geert Bultynck. (2013) Regulation of connexin- and pannexin-based channels by post-translational modifications. Biology of the Cell 105:9, pages 373-398.
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Nan Wang, Marijke De Bock, Elke Decrock, Mélissa Bol, Ashish Gadicherla, Mathieu Vinken, Vera Rogiers, Feliksas F. Bukauskas, Geert Bultynck & Luc Leybaert. (2013) Paracrine signaling through plasma membrane hemichannels. Biochimica et Biophysica Acta (BBA) - Biomembranes 1828:1, pages 35-50.
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Silvia Penuela, Ruchi Gehi & Dale W. Laird. (2013) The biochemistry and function of pannexin channels. Biochimica et Biophysica Acta (BBA) - Biomembranes 1828:1, pages 15-22.
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Honghong Zhang, Youting Chen & Chunbo Zhang. (2012) Patterns of heterogeneous expression of pannexin 1 and pannexin 2 transcripts in the olfactory epithelium and olfactory bulb. Journal of Molecular Histology 43:6, pages 651-660.
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Eduardo R. Lazarowski. (2012) Vesicular and conductive mechanisms of nucleotide release. Purinergic Signalling 8:3, pages 359-373.
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Silvia Penuela & Dale W. Laird. (2012) The cellular life of pannexins. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling 1:5, pages 621-632.
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Antonio Rodríguez-Sinovas, Jose A. Sánchez, Celia Fernandez-Sanz, Marisol Ruiz-Meana & David Garcia-Dorado. (2012) Connexin and pannexin as modulators of myocardial injury. Biochimica et Biophysica Acta (BBA) - Biomembranes 1818:8, pages 1962-1970.
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Rekha Kar, Nidhi Batra, Manuel A. Riquelme & Jean X. Jiang. (2012) Biological role of connexin intercellular channels and hemichannels. Archives of Biochemistry and Biophysics 524:1, pages 2-15.
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Stephen R. Bond, Nan Wang, Luc Leybaert & Christian C. Naus. (2012) Pannexin 1 Ohnologs in the Teleost Lineage. The Journal of Membrane Biology 245:8, pages 483-493.
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Scott R. Johnstone, Marie Billaud, Alexander W. Lohman, Evan P. Taddeo & Brant E. Isakson. (2012) Posttranslational Modifications in Connexins and Pannexins. The Journal of Membrane Biology 245:5-6, pages 319-332.
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Alexander W. Lohman, Marie Billaud, Adam C. Straub, Scott R. Johnstone, Angela K. Best, Monica Lee, Kevin Barr, Silvia Penuela, Dale W. Laird & Brant E. Isakson. (2012) Expression of Pannexin Isoforms in the Systemic Murine Arterial Network. Journal of Vascular Research 49:5, pages 405-416.
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Stephen R Bond, Alice Lau, Silvia Penuela, Arthur V Sampaio, T Michael Underhill, Dale W Laird & Christian C Naus. (2011) Pannexin 3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes. Journal of Bone and Mineral Research 26:12, pages 2911-2922.
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Masaki Ishikawa, Tsutomu Iwamoto, Takashi Nakamura, Andrew Doyle, Satoshi Fukumoto & Yoshihiko Yamada. (2011) Pannexin 3 functions as an ER Ca2+ channel, hemichannel, and gap junction to promote osteoblast differentiation. Journal of Cell Biology 193:7, pages 1257-1274.
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Catheleyne D'hondt, Raf Ponsaerts, Humbert De Smedt, Mathieu Vinken, Elke De Vuyst, Marijke De Bock, Nan Wang, Vera Rogiers, Luc Leybaert, Bernard Himpens & Geert Bultynck. (2011) Pannexin channels in ATP release and beyond: An unexpected rendezvous at the endoplasmic reticulum. Cellular Signalling 23:2, pages 305-316.
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Jennifer RobertsonSue LangPeter A. LambertPatricia E. Martin. (2010) Peptidoglycan derived from Staphylococcus epidermidis induces Connexin43 hemichannel activity with consequences on the innate immune response in endothelial cells. Biochemical Journal 432:1, pages 133-143.
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Leigh Anne Swayne, Catherine D. Sorbara & Steffany A.L. Bennett. (2010) Pannexin 2 Is Expressed by Postnatal Hippocampal Neural Progenitors and Modulates Neuronal Commitment. Journal of Biological Chemistry 285:32, pages 24977-24986.
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Tsutomu Iwamoto, Takashi Nakamura, Andrew Doyle, Masaki Ishikawa, Susana de Vega, Satoshi Fukumoto & Yoshihiko Yamada. (2010) Pannexin 3 Regulates Intracellular ATP/cAMP Levels and Promotes Chondrocyte Differentiation. Journal of Biological Chemistry 285:24, pages 18948-18958.
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Steven J. Celetti, Kyle N. Cowan, Silvia Penuela, Qing Shao, Jared Churko & Dale W. Laird. (2010) Implications of pannexin 1 and pannexin 3 for keratinocyte differentiation. Journal of Cell Science 123:8, pages 1363-1372.
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Ruchi Bhalla-Gehi, Silvia Penuela, Jared M. Churko, Qing Shao & Dale W. Laird. (2010) Pannexin1 and Pannexin3 Delivery, Cell Surface Dynamics, and Cytoskeletal Interactions. Journal of Biological Chemistry 285:12, pages 9147-9160.
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Brian A. MacVicar & Roger J. Thompson. (2010) Non-junction functions of pannexin-1 channels. Trends in Neurosciences 33:2, pages 93-102.
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Silvia Penuela, Ruchi Bhalla, Kakon Nag & Dale W. Laird. (2009) Glycosylation Regulates Pannexin Intermixing and Cellular Localization. Molecular Biology of the Cell 20:20, pages 4313-4323.
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Catheleyne D'hondt, Raf Ponsaerts, Humbert De Smedt, Geert Bultynck & Bernard Himpens. (2009) Pannexins, distant relatives of the connexin family with specific cellular functions?. BioEssays 31:9, pages 953-974.
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George R. Dubyak. (2009) Both sides now: multiple interactions of ATP with pannexin-1 hemichannels . Focus on “A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP” . American Journal of Physiology-Cell Physiology 296:2, pages C235-C241.
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