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Clinical Toxicology Volume 59, 2021 - Issue 1
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Clinical Research

Comparison of rates of opioid withdrawal symptoms and reversal of opioid toxicity in patients treated with two naloxone dosing regimens: a retrospective cohort study

Roy Purssella Department of Emergency Medicine, University of British Columbia, Vancouver, Canada;b British Columbia Drug and Poison Information Centre, British Columbia Centre for Disease Control, Vancouver, CanadaCorrespondence[email protected]
,
Jesse Godwina Department of Emergency Medicine, University of British Columbia, Vancouver, Canada;b British Columbia Drug and Poison Information Centre, British Columbia Centre for Disease Control, Vancouver, Canada
,
Jessica Moea Department of Emergency Medicine, University of British Columbia, Vancouver, Canada
,
Jane Buxtonc School of Population and Public Health, University of British Columbia, Vancouver, Canada
,
Alexis Crabtreec School of Population and Public Health, University of British Columbia, Vancouver, Canada
,
Andrew Kestlera Department of Emergency Medicine, University of British Columbia, Vancouver, Canada
,
Chris DeWitta Department of Emergency Medicine, University of British Columbia, Vancouver, Canada;b British Columbia Drug and Poison Information Centre, British Columbia Centre for Disease Control, Vancouver, Canada
,
Frank Scheuermeyera Department of Emergency Medicine, University of British Columbia, Vancouver, Canada
,
Shannon Erdelyia Department of Emergency Medicine, University of British Columbia, Vancouver, Canada
,
Robert Balshawd Department of Community Health Sciences, Faculty of Health Sciences, College of Medicine, University of Manitoba, Winnipeg, Canada
,
Adrianna Rowea Department of Emergency Medicine, University of British Columbia, Vancouver, Canada
,
Christopher K. Cochranea Department of Emergency Medicine, University of British Columbia, Vancouver, Canada
,
Benjamin Nga Department of Emergency Medicine, University of British Columbia, Vancouver, Canada
,
Andy Jianga Department of Emergency Medicine, University of British Columbia, Vancouver, Canada
,
Alessia Risie Faculty of Pharmacy, University of British Columbia, Vancouver, Canada
,
Vi Hoa Department of Emergency Medicine, University of British Columbia, Vancouver, Canada
&
Jeffrey R. Brubachera Department of Emergency Medicine, University of British Columbia, Vancouver, Canada
 show all
Pages 38-46 | Received 17 Dec 2019, Accepted 14 Apr 2020, Published online: 13 May 2020

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Jessica Xavier, Alissa Greer, Alexis Crabtree & Jane A. Buxton. (2023) Police officers’ perceptions of their role at overdose events: a qualitative study. Drugs: Education, Prevention and Policy 30:4, pages 361-372.
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Roy Purssell, Jesse Godwin, Jessica Moe, Jane Buxton, Andrew Kestler & Jeffrey R. Brubacher. (2021) Authors' reply to Comment on Comparison of rates of opioid withdrawal symptoms and reversal of opioid toxicity in patients treated with two naloxone dosing regimens. Clinical Toxicology 59:1, pages 80-81.
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Mohamed Y. Jefri & Lewis S. Nelson. (2021) Comment on Comparison of rates of opioid withdrawal symptoms and reversal of opioid toxicity in patients treated with two naloxone dosing regimens. Clinical Toxicology 59:1, pages 79-80.
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James N. Bates, Paulina M. Getsy, Gregory A. Coffee, Santhosh M. Baby, Peter M. MacFarlane, Yee-Hsee Hsieh, Zackery T. Knauss, Jason A. Bubier, Devin Mueller & Stephen J. Lewis. (2023) L-cysteine ethyl ester prevents and reverses acquired physical dependence on morphine in male Sprague Dawley rats. Frontiers in Pharmacology 14.
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Katherine R. Marks, Douglas R. Oyler, Justin C. Strickland, Jody Jaggers, Monica F. Roberts, Dustin K. Miracle, Chase Barnes, Feitong Lei, Amanda Smith, Eric Mackin, Martika C. Martin & Patricia R. Freeman. (2023) Bystander preference for naloxone products: a field experiment. Harm Reduction Journal 20:1.
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Eric J. Lavonas, Peter D. Akpunonu, Ann M. Arens, Kavita M. Babu, Dazhe Cao, Robert S. Hoffman, Christopher O. Hoyte, Maryann E. Mazer-Amirshahi, Andrew Stolbach, Maude St-Onge, Trevonne M. Thompson, George Sam Wang, Amber V. Hoover & Ian R. Drennan. (2023) 2023 American Heart Association Focused Update on the Management of Patients With Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation.
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Bianca Yugar, Kelly McManus, Christine Ramdin, Lewis S. Nelson & Mehruba Anwar Parris. (2023) SYSTEMATIC REVIEW OF NALOXONE DOSING AND ADVERSE EVENTS IN THE EMERGENCY DEPARTMENT. The Journal of Emergency Medicine.
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Renata C.N. Marchette, Erika R. Carlson, Emma V. Frye, Lyndsay E. Hastings, Janaina C.M. Vendruscolo, Gustavo Mejias-Torres, Stephen J. Lewis, Aidan Hampson, Nora D. Volkow, Leandro F. Vendruscolo & George F. Koob. (2023) Heroin- and Fentanyl-Induced Respiratory Depression in a Rat Plethysmography Model: Potency, Tolerance, and Sex Differences. Journal of Pharmacology and Experimental Therapeutics 385:2, pages 117-134.
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Jamil Danaf, Carolina da Silveira Scarpellini & Gaspard Montandon. (2023) βγ G-proteins, but not regulators of G-protein signaling 4, modulate opioid-induced respiratory rate depression. Frontiers in Physiology 14.
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Rachel Luba, Jermaine Jones, C. Jean Choi & Sandra Comer. (2022) Fentanyl withdrawal: Understanding symptom severity and exploring the role of body mass index on withdrawal symptoms and clearance. Addiction 118:4, pages 719-726.
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Stevie C. Britch & Sharon L. Walsh. (2022) Treatment of opioid overdose: current approaches and recent advances. Psychopharmacology 239:7, pages 2063-2081.
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Lucas G. Hill, Claire M. Zagorski & Lindsey J. Loera. (2022) Increasingly powerful opioid antagonists are not necessary. International Journal of Drug Policy 99, pages 103457.
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