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Review Article

Carnitine in the treatment of valproic acid-induced toxicity

Philippe E.R. LheureuxDepartment of Emergency Medicine, Acute Poisoning Unit, Erasme University Hospital, Université Libre de Bruxelles, Brussels, BelgiumCorrespondence[email protected]
&
Philippe HantsonDepartment of Intensive Care, St Luc University Hospital, Université Catholique de Louvain, Brussels, Belgium
Pages 101-111 | Received 15 Jan 2009, Accepted 15 Jan 2009, Published online: 01 Feb 2009

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Yujia Chen, Shuanghui Lu, Yingqiong Zhang, Binxin Chen, Hui Zhou & Huidi Jiang. (2022) Examination of the emerging role of transporters in the assessment of nephrotoxicity. Expert Opinion on Drug Metabolism & Toxicology 18:11, pages 787-804.
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Marc Ghannoum, Martin Laliberté, Thomas D. Nolin, Robert MacTier, Valery Lavergne, Robert S. Hoffman & Sophie Gosselin. (2015) Extracorporeal treatment for valproic acid poisoning: Systematic review and recommendations from the EXTRIP workgroup. Clinical Toxicology 53:5, pages 454-465.
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. (2014) XXXIV International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT) 27–30 May 2014, Brussels, Belgium. Clinical Toxicology 52:4, pages 295-443.
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Dana Felker, Alexandra Lynn, Sue Wang & Dale E Johnson. (2014) Evidence for a potential protective effect of carnitine-pantothenic acid co-treatment on valproic acid-induced hepatotoxicity. Expert Review of Clinical Pharmacology 7:2, pages 211-218.
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Chandani Lewis, Abhishek Deshpande, George E. Tesar & Roman Dale. (2012) Valproate-induced hyperammonemic encephalopathy: a brief review. Current Medical Research and Opinion 28:6, pages 1039-1042.
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Robert A. Roth & Patricia E. Ganey. (2011) Animal models of idiosyncratic drug-induced liver injury—Current status. Critical Reviews in Toxicology 41:9, pages 723-739.
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Thomas Bøhmer, Anne Bøen & Siv Cathrine Høymork. (2010) Valproate-induced hyperammonemic encephalopathy, rapidly improved by i.v. carnitine and glucose/thiamine. Scandinavian Journal of Gastroenterology 45:6, pages 762-763.
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Brigitte V Lovell & Michael J Marmura. (2010) Valproate semisodium ER for migraine and cluster headache prophylaxis. Expert Opinion on Drug Metabolism & Toxicology 6:4, pages 495-504.
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Ruben H.K. Thanacoody. (2009) Extracorporeal elimination in acute valproic acid poisoning. Clinical Toxicology 47:7, pages 609-616.
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