630
Views
32
CrossRef citations to date
0
Altmetric
Review

Application of freeze-drying in the development of oral drug delivery systems

, &
Pages 1595-1608 | Received 13 Mar 2016, Accepted 02 Jun 2016, Published online: 20 Jun 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Ankit Patil, Pritam Patil, Sagar Pardeshi, Preena Shrimal, Norma Rebello, Popat B. Mohite, Aniruddha Chatterjee, Arun Mujumdar & Jitendra Naik. (2023) Combined microfluidics and drying processes for the continuous production of micro-/nanoparticles for drug delivery: a review. Drying Technology 41:10, pages 1533-1568.
Read now
Pengfei Yue, Weicheng Zhou, Guiting Huang, Fangfang Lei, Yingchong Chen, Zhilin Ma, Liru Chen & Ming Yang. (2022) Nanocrystals based pulmonary inhalation delivery system: advance and challenge. Drug Delivery 29:1, pages 637-651.
Read now
Sagar Pardeshi, Mahesh More, Pritam Patil, Chandrakantsing Pardeshi, Prashant Deshmukh, Arun Mujumdar & Jitendra Naik. (2021) A meticulous overview on drying-based (spray-, freeze-, and spray-freeze) particle engineering approaches for pharmaceutical technologies. Drying Technology 39:11, pages 1447-1491.
Read now
Aurica P. Chiriac, Alina Diaconu, Loredana E. Nita, Nita Tudorachi, Liliana Mititelu-Tartau, Andreea Creteanu, Oana Dragostin, Daniela Rusu & Gratiela Popa. (2017) The influence of excipients on physical and pharmaceutical properties of oral lyophilisates containing a pregabalin-acetaminophen combination. Expert Opinion on Drug Delivery 14:5, pages 589-599.
Read now

Articles from other publishers (28)

Sagar R. Pardeshi, Nilesh S. Deshmukh, Darshan R. Telange, Sopan N. Nangare, Yogesh Y. Sonar, Sameer H. Lakade, Minal T. Harde, Chandrakantsing V. Pardeshi, Amol Gholap, Prashant K. Deshmukh & Mahesh P. More. (2023) Process development and quality attributes for the freeze-drying process in pharmaceuticals, biopharmaceuticals and nanomedicine delivery: a state-of-the-art review. Future Journal of Pharmaceutical Sciences 9:1.
Crossref
Madan Sai Poka, Marnus Milne, Anita Wessels & Marique Aucamp. (2023) Sugars and Polyols of Natural Origin as Carriers for Solubility and Dissolution Enhancement. Pharmaceutics 15:11, pages 2557.
Crossref
Zhi Shi, Guobin Huang, Zhongming Li, Zhenkai Lou, Zhiqiang Gong, Xin Wang, Chengyong Li & Bing Wang. (2023) A PLA-tPU based magnesium ion incorporated CSH/nHA bioactive porous composite scaffold for critical bone defect repair. Materials Advances 4:16, pages 3583-3592.
Crossref
Luo Chun, Mi Sha, Zhou Naijun, Liu Zhiqiang & Shi Wenjun. (2023) Real-time observation of the freezing stage of the mannitol solution using high-resolution optical microscopy. International Journal of Thermal Sciences 188, pages 108225.
Crossref
Kimberley Elbrink, Sofie Van Hees, René Holm & Filip Kiekens. (2023) Optimization of the different phases of the freeze-drying process of solid lipid nanoparticles using experimental designs. International Journal of Pharmaceutics 635, pages 122717.
Crossref
Nasser Alhajj, Niall J. O’Reilly & Helen Cathcart. 2023. Pulmonary Drug Delivery Systems: Material and Technological Advances. Pulmonary Drug Delivery Systems: Material and Technological Advances 91 129 .
Wedja Timóteo Vieira, Maria Vitória Silva Nicollini, Meuris Gurgel Carlos da Silva, Laura de Oliveira Nascimento & Melissa Gurgel Adeodato Vieira. (2022) Natural polysaccharides and proteins applied to the development of gastroresistant multiparticulate systems for anti-inflammatory drug delivery – A systematic review. European Polymer Journal 172, pages 111205.
Crossref
Filipa Castro, Nuno Ribeiro da Silva, Sara Cruz Silvério, Lina Fernanda Ballesteros & José António Teixeira. 2022. Current Developments in Biotechnology and Bioengineering. Current Developments in Biotechnology and Bioengineering 455 495 .
R. Olmos-Juste, O. Guaresti, T. Calvo-Correas, N. Gabilondo & A. Eceiza. (2021) Design of drug-loaded 3D printing biomaterial inks and tailor-made pharmaceutical forms for controlled release. International Journal of Pharmaceutics 609, pages 121124.
Crossref
Tarek A. Ahmed. (2021) Study the pharmacokinetics, pharmacodynamics and hepatoprotective activity of rosuvastatin from drug loaded lyophilized orodispersible tablets containing transfersomes nanoparticles. Journal of Drug Delivery Science and Technology 63, pages 102489.
Crossref
Ye Chen, Qibin Liao, Tianyue Chen, Yuchao Zhang, Weien Yuan, Jianqing Xu & Xiaoyan Zhang. (2020) Freeze-Drying Formulations Increased the Adenovirus and Poxvirus Vaccine Storage Times and Antigen Stabilities. Virologica Sinica 36:3, pages 365-372.
Crossref
Angela Abruzzo, Alessandra Crispini, Cecilia Prata, Rosanna Adduci, Fiore Pasquale Nicoletta, Francesco Dalena, Teresa Cerchiara, Barbara Luppi & Federica Bigucci. (2021) Freeze-Dried Matrices for Buccal Administration of Propranolol in Children: Physico-Chemical and Functional Characterization. Journal of Pharmaceutical Sciences 110:4, pages 1676-1686.
Crossref
Emilia Jakubowska & Janina Lulek. (2021) The application of freeze-drying as a production method of drug nanocrystals and solid dispersions – A review. Journal of Drug Delivery Science and Technology 62, pages 102357.
Crossref
John Ndayishimiye, Amirali Popat, Tushar Kumeria, Mark A.T. Blaskovich & James Robert Falconer. (2021) Supercritical carbon dioxide assisted complexation of benznidazole: γ-cyclodextrin for improved dissolution. International Journal of Pharmaceutics 596, pages 120240.
Crossref
Suryanarayana Polaka, Nimeet Desai, Bhavesh Kshirsagar, Kuldeep Rajpoot & Rakesh Kumar Tekade. 2021. Biopharmaceutics and Pharmacokinetics Considerations. Biopharmaceutics and Pharmacokinetics Considerations 387 413 .
Khater A. S. Al-Japairai, Hala M. Alkhalidi, Syed Mahmood, Samah H. Almurisi, Abd Almonem Doolaanea, Taha A. Al-Sindi & Bappaditya Chatterjee. (2020) Lyophilized Amorphous Dispersion of Telmisartan in a Combined Carrier–Alkalizer System: Formulation Development and In Vivo Study . ACS Omega 5:50, pages 32466-32480.
Crossref
Tao Liu, Xinxin Yu & Haipeng Yin. (2020) Impact of nanoparticle size and solid state on dissolution rate by investigating modified drug powders. Powder Technology 376, pages 167-175.
Crossref
Kaifei Chen, Wei Feng, Zongda Jia, Ziming Xu, Lisa Xu & Gang Li. (2020) Cryogenic-crosslink synthesis of Ba(OH)2@gelatin microcapsules for the removal of sulfate in lithium refinery. Hydrometallurgy 195, pages 105342.
Crossref
Tao Liu, Xinxin Yu & Haipeng Yin. (2020) Study of Top-down and Bottom-up Approaches by Using Design of Experiment (DoE) to Produce Meloxicam Nanocrystal Capsules. AAPS PharmSciTech 21:3.
Crossref
Barbara Giordani, Angela Abruzzo, Cecilia Prata, Fiore Pasquale Nicoletta, Francesco Dalena, Teresa Cerchiara, Barbara Luppi & Federica Bigucci. (2020) Ondansetron buccal administration for paediatric use: A comparison between films and wafers. International Journal of Pharmaceutics 580, pages 119228.
Crossref
Giulia Auriemma, Andrea Cerciello, Rita P. Aquino, Pasquale Del Gaudio, Bruno M. Fusco & Paola Russo. (2020) Pectin and Zinc Alginate: The Right Inner/Outer Polymer Combination for Core-Shell Drug Delivery Systems. Pharmaceutics 12:2, pages 87.
Crossref
Carin Ru Shan Siow, Denyse Shuwen Tang, Paul Wan Sia Heng & Lai Wah Chan. (2019) Probing the impact of HPMC viscosity grade and proportion on the physical properties of co-freeze-dried mannitol-HPMC tableting excipients using multivariate analysis methods. International Journal of Pharmaceutics 556, pages 246-262.
Crossref
Alina Porfire, Ioan Tomuta, Sonia Iurian & Tibor Casian. 2019. Pharmaceutical Quality by Design. Pharmaceutical Quality by Design 193 207 .
Carin Ru Shan Siow, Paul Wan Sia Heng & Lai Wah Chan. (2017) Bulk Freeze-Drying Milling: a Versatile Method of Developing Highly Porous Cushioning Excipients for Compacted Multiple-Unit Pellet Systems (MUPS). AAPS PharmSciTech 19:2, pages 845-857.
Crossref
Tao Liu, Guili Yao, Xue Zhang, Ximin Zuo, Lihong Wang, Haipeng Yin & Jan P. Möschwitzer. (2017) Systematical Investigation of Different Drug Nanocrystal Technologies to Produce Fast Dissolving Meloxicam Tablets. AAPS PharmSciTech 19:2, pages 783-791.
Crossref
Francesco Cilurzo, Umberto M. Musazzi, Silvia Franzé, Francesca Selmin & Paola Minghetti. (2018) Orodispersible dosage forms: biopharmaceutical improvements and regulatory requirements. Drug Discovery Today 23:2, pages 251-259.
Crossref
Timothy Pas, Bjorn Vergauwen & Guy Van den Mooter. (2018) Exploring the feasibility of the use of biopolymers as a carrier in the formulation of amorphous solid dispersions – Part I: Gelatin. International Journal of Pharmaceutics 535:1-2, pages 47-58.
Crossref
Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz & Marian PaluchMarzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz & Marian Paluch. 2018. Amorphous Drugs. Amorphous Drugs 69 106 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.