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Nanotoxicology Volume 12, 2018 - Issue 9
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Article

Autophagy-dependent release of zinc ions is critical for acute lung injury triggered by zinc oxide nanoparticles

Xuejun JiangCenter of Experimental Teaching for Public Health, Experimental Teaching and Management Center, Chongqing Medical University, Chongqing, People’s Republic of China; ;Laboratory of Tissue and Cell Biology, Experimental Teaching and Management Center, Chongqing Medical University, Chongqing, People’s Republic of China; View further author information
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Qianghu TangDepartment of Occupational and Environmental Health, School of Public Health and Management, Research Center for Medicine and Social Development, Innovation Center for Social Risk Governance in Health, Chongqing Medical University, Chongqing, People’s Republic of China; View further author information
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Jun ZhangInstitute of Life Sciences, Chongqing Medical University, Chongqing, People’s Republic of China; View further author information
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Hong WangInstitute of Life Sciences, Chongqing Medical University, Chongqing, People’s Republic of China; View further author information
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Lulu BaiDepartment of Occupational and Environmental Health, School of Public Health and Management, Research Center for Medicine and Social Development, Innovation Center for Social Risk Governance in Health, Chongqing Medical University, Chongqing, People’s Republic of China; View further author information
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Pan MengDepartment of Occupational and Environmental Health, School of Public Health and Management, Research Center for Medicine and Social Development, Innovation Center for Social Risk Governance in Health, Chongqing Medical University, Chongqing, People’s Republic of China; View further author information
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Xia QinDepartment of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; View further author information
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Ge XuInstitute of Life Sciences, Chongqing Medical University, Chongqing, People’s Republic of China; View further author information
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Diptiman D. BoseDepartment of Pharmaceutical and Administrative Sciences, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA, USA; View further author information
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Bin WangInstitute of Life Sciences, Chongqing Medical University, Chongqing, People’s Republic of China; View further author information
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Chengzhi ChenDepartment of Occupational and Environmental Health, School of Public Health and Management, Research Center for Medicine and Social Development, Innovation Center for Social Risk Governance in Health, Chongqing Medical University, Chongqing, People’s Republic of China; ;Post-doctoral Research Stations of Nursing Science, School of Nursing, Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence[email protected] [email protected]
ORCID Iconhttp://orcid.org/0000-0002-1087-4911View further author information
ORCID Icon &
Zhen ZouInstitute of Life Sciences, Chongqing Medical University, Chongqing, People’s Republic of China; Correspondence[email protected] [email protected]
ORCID Iconhttp://orcid.org/0000-0002-1651-591XView further author information
ORCID Icon show all
Pages 1068-1091 | Received 18 Apr 2018, Accepted 14 Aug 2018, Published online: 14 Oct 2018

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Cantao Yang, Zhaohong Lu, Yinyin Xia, Jun Zhang, Zhen Zou, Chengzhi Chen, Xiaoliang Wang, Xin Tian, Shuqun Cheng & Xuejun Jiang. (2023) Alterations of Gut-Derived Melatonin in Neurobehavioral Impairments Caused by Zinc Oxide Nanoparticles. International Journal of Nanomedicine 18, pages 1899-1914.
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Xia Qin, Jun Zhang, Bin Wang, Ge Xu, Xi Yang, Zhen Zou & Chao Yu. (2021) Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells. Autophagy 17:12, pages 4266-4285.
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Longbin Zhang, Liyong Zou, Xuejun Jiang, Shuqun Cheng, Jun Zhang, Xia Qin, Zhexue Qin, Chengzhi Chen & Zhen Zou. (2021) Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death. Nanotoxicology 15:6, pages 779-797.
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Hui He, Zhen Zou, Bin Wang, Ge Xu, Chengzhi Chen, Xia Qin, Chao Yu & Jun Zhang. (2020) Copper Oxide Nanoparticles Induce Oxidative DNA Damage and Cell Death via Copper Ion-Mediated P38 MAPK Activation in Vascular Endothelial Cells. International Journal of Nanomedicine 15, pages 3291-3302.
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S. Keerthana & A. Kumar. (2020) Potential risks and benefits of zinc oxide nanoparticles: a systematic review. Critical Reviews in Toxicology 50:1, pages 47-71.
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Xuemei Liu, Bin Wang, Xuejun Jiang, Jun Zhang, Qianghu Tang, Yujia Zhang, Xia Qin, Chengzhi Chen & Zhen Zou. (2019) Heterozygous Disruption of Beclin 1 Alleviates Zinc Oxide Nanoparticles-Induced Disturbance of Cholesterol Biosynthesis in Mouse Liver. International Journal of Nanomedicine 14, pages 9865-9875.
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