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Expert Review of Respiratory Medicine Volume 11, 2017 - Issue 11
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Review

The role of upper airway pathology as a co-morbidity in severe asthma

Amelia LicariDepartment of Pediatrics, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyORCID Iconhttp://orcid.org/0000-0002-1773-6482View further author information
ORCID Icon,
Ilaria BrambillaDepartment of Pediatrics, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyView further author information
,
Maria De FilippoDepartment of Pediatrics, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyView further author information
,
Dimitri PoddigheDepartment of Pediatrics, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy;Department of Pediatrics, ASST Melegnano e Martesana, Milan, ItalyView further author information
,
Riccardo CastagnoliDepartment of Pediatrics, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyView further author information
&
Gian Luigi MarsegliaDepartment of Pediatrics, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-3662-0159View further author information
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Pages 855-865 | Received 07 Aug 2017, Accepted 15 Sep 2017, Published online: 21 Sep 2017

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Amelia Licari, Beatrice Andrenacci, Maria Elisa Di Cicco, Maddalena Leone, Gian Luigi Marseglia & Mariangela Tosca. (2023) Respiratory comorbidities in severe asthma: focus on the pediatric age. Expert Review of Respiratory Medicine 17:1, pages 1-13.
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Shingo Tsuneyoshi, Tomotaka Kawayama, Jun Sasaki, Takashi Kinoshita, Chiyo Yano, Yoshihisa Tokunaga, Masanobu Matsuoka, Haruki Imaoka, Kazuko Matsunaga, Kyoji Furukawa & Tomoaki Hoshino. (2022) Poor Asthma Control in Schoolchildren May Lead to Lower Lung Function Trajectory from Childhood to Early Adulthood: A Japanese Cohort Study. Journal of Asthma and Allergy 15, pages 885-896.
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Seyed Vahid Razavi-Termeh, Abolghasem Sadeghi-Niaraki & Soo-Mi Choi. (2022) Spatio-temporal modelling of asthma-prone areas using a machine learning optimized with metaheuristic algorithms. Geocarto International 37:25, pages 9917-9942.
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Beatrice Andrenacci, Giuliana Ferrante, Giulia Roberto, Giorgio Piacentini, Stefania La Grutta, Gian Luigi Marseglia & Amelia Licari. (2022) Challenges in uncontrolled asthma in pediatrics: important considerations for the clinician. Expert Review of Clinical Immunology 18:8, pages 807-821.
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Martina Votto, Maria De Filippo, Amelia Licari, Alessia Marseglia, Mara De Amici & Gian Luigi Marseglia. (2021) Biological Therapies in Children and Adolescents with Severe Uncontrolled Asthma: A Practical Review. Biologics: Targets and Therapy 15, pages 133-142.
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Maria De Filippo, Martina Votto, Amelia Licari, Fabio Pagella, Marco Benazzo, Giorgio Ciprandi & Gian Luigi Marseglia. (2021) Novel therapeutic approaches targeting endotypes of severe airway disease. Expert Review of Respiratory Medicine 15:10, pages 1303-1316.
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Riccardo Castagnoli, Amelia Licari, Ilaria Brambilla, Mariangela Tosca, Giorgio Ciprandi & Gian Luigi Marseglia. (2020) An update on the role of chronic rhinosinusitis with nasal polyps as a co-morbidity in severe asthma. Expert Review of Respiratory Medicine 14:12, pages 1197-1205.
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Giovanni Battista Pajno, Riccardo Castagnoli, Stefania Arasi, Amelia Licari, Lucia Caminiti & Gian Luigi Marseglia. (2020) Pediatric use of omalizumab for allergic asthma. Expert Opinion on Biological Therapy 20:7, pages 695-703.
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Amelia Licari, Riccardo Castagnoli, Maria De Filippo, Thomas Foiadelli, Maria Angela Tosca, Gian Luigi Marseglia & Giorgio Ciprandi. (2020) Current and emerging biologic therapies for allergic rhinitis and chronic rhinosinusitis. Expert Opinion on Biological Therapy 20:6, pages 609-619.
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Amelia Licari, Riccardo Castagnoli, Maria Angela Tosca, Gianluigi Marseglia & Giorgio Ciprandi. (2019) Personalized therapies for the treatment of allergic rhinitis. Expert Review of Precision Medicine and Drug Development 4:5, pages 275-281.
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Amelia Licari, Sara Manti & Giorgio Ciprandi. (2019) What are the effects of rhinitis on patients with asthma?. Expert Review of Respiratory Medicine 13:6, pages 503-505.
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Ludger Klimek, Annette Sperl, Sven Becker, Ralph Mösges & Peter Valentin Tomazic. (2019) Current therapeutical strategies for allergic rhinitis. Expert Opinion on Pharmacotherapy 20:1, pages 83-89.
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Amelia Licari & Gian Luigi Marseglia. (2018) Current and future challenges in pediatric severe asthma. Current Medical Research and Opinion 34:5, pages 943-944.
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Mona Al-Ahmad, Asmaa Ali, Mustafa Khalaf, Abdulmohsen Alterki & Tito Rodriguez-Bouza. (2023) Comorbid asthma in patients with chronic rhinosinusitis with nasal polyps: did dupilumab make a difference?. BMC Pulmonary Medicine 23:1.
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Taye Mekonnen, Xinyu Cai, Christopher Burchell, Hanieh Gholizadeh & Shaokoon Cheng. (2022) A review of upper airway physiology relevant to the delivery and deposition of inhalation aerosols. Advanced Drug Delivery Reviews 191, pages 114530.
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Cynthia A. Pate, Hatice S. Zahran, Josephine Malilay & Joy Hsu. (2022) The shifting prevalence of asthma and allergic disease in US children. Annals of Allergy, Asthma & Immunology 129:4, pages 481-489.
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Nicola Ullmann, Francesca Peri, Olivia Florio, Federica Porcaro, Elisa Profeti, Alessandro Onofri & Renato Cutrera. (2022) Severe Pediatric Asthma Therapy: Mepolizumab. Frontiers in Pediatrics 10.
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Markus A. Rose. (2021) Biologika beim schweren/schwierigen Asthma bronchiale im Kindes- und JugendalterBiologicals for severe/difficult bronchial asthma in childhood and adolescence. Der Pneumologe 18:6, pages 395-404.
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Ted Klok, Mark D. Ottink & Paul L.P. Brand. (2021) Question 6: What is the use of allergy testing in children with asthma?. Paediatric Respiratory Reviews 37, pages 57-63.
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Tanya M. Laidlaw, Joaquim Mullol, Katharine M. Woessner, Nikhil Amin & Leda P. Mannent. (2021) Chronic Rhinosinusitis with Nasal Polyps and Asthma. The Journal of Allergy and Clinical Immunology: In Practice 9:3, pages 1133-1141.
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Archita Ray, Sabita Singh, Joytri Dutta & Ulaganathan Mabalirajan. 2021. Targeting Cellular Signalling Pathways in Lung Diseases. Targeting Cellular Signalling Pathways in Lung Diseases 27 51 .
Amelia Licari, Sara Manti, Alessia Marseglia, Maria De Filippo, Elisabetta De Sando, Thomas Foiadelli & Gian Luigi Marseglia. (2020) Biologics in Children with Allergic Diseases. Current Pediatric Reviews 16:2, pages 140-147.
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Riccardo Castagnoli, Alessia Marseglia, Ilaria Brambilla, Gian Luigi Marseglia & Amelia Licari. (2020) Severe uncontrolled asthma in children: practical approach on diagnosis and management. Minerva Pediatrica 72:3.
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Amelia Licari, Riccardo Castagnoli, Alessia Marseglia, Francesca Olivero, Martina Votto, Giorgio Ciprandi & Gian Luigi Marseglia. (2020) Dupilumab to Treat Type 2 Inflammatory Diseases in Children and Adolescents. Pediatric Drugs 22:3, pages 295-310.
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İnsu YILMAZ, Murat TÜRK, Sakine BAHÇECİOĞLU, Nuri TUTAR & İnci GÜLMEZ. (2020) Efficacy of mepolizumab treatment in oral corticosteroid-dependent severe eosinophilic asthma patients with chronic rhinosinusitis with nasal polyps: single center, real life study. TURKISH JOURNAL OF MEDICAL SCIENCES 44:2, pages 433-441.
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Amelia Licari, Sara Manti, Riccardo Castagnoli, Salvatore Leonardi & Gian Luigi Marseglia. (2020) Measuring inflammation in paediatric severe asthma: biomarkers in clinical practice. Breathe 16:1, pages 190301.
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Amelia Licari, Sara Manti, Elena Chiappini, Giorgio Ciprandi & Gian Luigi Marseglia. (2020) Severe asthma in children: Current goals and unmet needs. Pediatric Allergy and Immunology 31:S24, pages 40-42.
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Amelia Licari, Riccardo Castagnoli, Enrico Tondina, Giorgia Testa, Giuseppe Fabio Parisi, Alessia Marseglia, Ilaria Brambilla & Gian Luigi Marseglia. (2020) Novel Biologics for the Treatment of Pediatric Severe Asthma. Current Respiratory Medicine Reviews 15:3, pages 195-204.
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Amelia Licari, Riccardo Castagnoli, Enrica Manca, Martina Votto, Alexander Michev & Gian Luigi Marseglia. (2020) Towards Precision Medicine in Pediatric Severe Asthma: An Update on Current and Emerging Biomarkers. Current Respiratory Medicine Reviews 15:3, pages 187-194.
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Mattia Giovannini, Francesca Mori, Simona Barni, Maurizio de Martino & Elio Novembre. (2019) Omalizumab and mepolizumab in the landscape of biological therapy for severe asthma in children: how to choose?. Italian Journal of Pediatrics 45:1.
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Е. Е. Lokshina & О. V. Zaytseva. (2019) Inhalation therapy in children: new opportunities. Russian Pulmonology 29:4, pages 499-507.
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Amelia Licari, Sara Manti, Riccardo Castagnoli, Giuseppe Fabio Parisi, Carmelo Salpietro, Salvatore Leonardi & Gian Luigi Marseglia. (2019) Targeted Therapy for Severe Asthma in Children and Adolescents: Current and Future Perspectives. Pediatric Drugs 21:4, pages 215-237.
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Landon Massoth, Cody Anderson & Kibwei A. McKinney. (2019) Asthma and Chronic Rhinosinusitis: Diagnosis and Medical Management. Medical Sciences 7:4, pages 53.
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Arianna Fallacara, Laura Busato, Michele Pozzoli, Maliheh Ghadiri, Hui Xin Ong, Paul M. Young, Stefano Manfredini & Daniela Traini. (2019) In vitro characterization of physico-chemical properties, cytotoxicity, bioactivity of urea-crosslinked hyaluronic acid and sodium ascorbyl phosphate nasal powder formulation. International Journal of Pharmaceutics 558, pages 341-350.
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Stephen T. Holgate, Samantha Walker, Brigitte West & Kay Boycott. (2019) The Future of Asthma Care. Clinics in Chest Medicine 40:1, pages 227-241.
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Antonio Pizzulli, Serena Perna, Anja Bennewiz, Holger Roeblitz, Salvatore Tripodi, Jakob Florack, Petra Wagner, Stephanie Hofmaier & Paolo Maria Matricardi. (2018) The impact of nasal aspiration with an automatic device on upper and lower respiratory symptoms in wheezing children: a pilot case-control study. Italian Journal of Pediatrics 44:1.
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Tatyana I. Eliseeva, Svetlana V. Krasilnikova, Sergey Yu. Babaev, Alexey A. Novozhilov, Dmitry Yu. Ovsyannikov, Stanislav K. Ignatov, Nailya I. Kubysheva & Andrey V. Shakhov. (2018) Dependence of Anterior Active Rhinomanometry Indices on Nasal Obstructive Disorders in Children with Atopic Bronchial Asthma Complicated by Nasal Symptoms. BioMed Research International 2018, pages 1-10.
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Barbara Boutopoulou, Despoina Koumpagioti, Vasiliki Matziou, Kostas N. Priftis & Konstantinos Douros. (2018) Interventions on Adherence to Treatment in Children With Severe Asthma: A Systematic Review. Frontiers in Pediatrics 6.
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Amelia Licari, Ilaria Brambilla, Alessia Marseglia, Maria De Filippo, Valeria Paganelli & Gian L. Marseglia. (2018) Difficult vs. Severe Asthma: Definition and Limits of Asthma Control in the Pediatric Population. Frontiers in Pediatrics 6.
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Amelia Licari, Ilaria Brambilla, Riccardo Castagnoli, Alessia Marseglia, Valeria Paganelli, Thomas Foiadelli & Gian Marseglia. (2018) Rhinosinutis and Asthma in Children. Sinusitis 3:2, pages 3.
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