https://orcid.org/0000-0002-3587-5603
Citations (48)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Young D. Kwon, Amarendra Pegu, Eun Sung Yang, Baoshan Zhang, Michael F. Bender, Mangaiarkarasi Asokan, Qingbo Liu, Krisha McKee, Bob C. Lin, Tracy Liu, Mark K. Louder, Reda Rawi, Mateo Reveiz, Andrew J. Schaub, Chen-Hsiang Shen, Nicole A. Doria-Rose, Paolo Lusso, John R. Mascola & Peter D. Kwong. (2023) Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain. mAbs 15:1.
Read now
Read now
Dhuha H Nawab. (2021) Vaccinal antibodies: Fc antibody engineering to improve the antiviral antibody response and induce vaccine-like effects. Human Vaccines & Immunotherapeutics 17:12, pages 5532-5545.
Read now
Read now
Jeffrey L. Wong & Jonathan E. Rosenberg. (2021) Targeting nectin-4 by antibody-drug conjugates for the treatment of urothelial carcinoma. Expert Opinion on Biological Therapy 21:7, pages 863-873.
Read now
Read now
Delphine Valente, Christine Mauriac, Thorsten Schmidt, Ingo Focken, Jochen Beninga, Brian Mackness, Huawei Qiu, Pascale Vicat, Abdullah Kandira, Katarina Radošević, Srini Rao, John Darbyshire & Mostafa Kabiri. (2020) Pharmacokinetics of novel Fc-engineered monoclonal and multispecific antibodies in cynomolgus monkeys and humanized FcRn transgenic mouse models. mAbs 12:1.
Read now
Read now
Articles from other publishers (44)
Nandagopal Paneerselvam, Amber Khan & Brian R. Lawson. (2023) Broadly neutralizing antibodies targeting HIV: Progress and challenges. Clinical Immunology 257, pages 109809.
Crossref
Crossref
Azam RahimpourMeysam MosallaeiFarzad PourghaziSayed Hassan TabatabaeeReyhaneh HoseinpoorEs'hagh PourmalekiMohsen Soosanabadi. (2023) Development of an Expression Vector Engineering Strategy Based on tDNA Insulator Element for the Stable Expression of Vascular Endothelial Growth Factor Receptor-Fc Fusion Protein. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 42:4, pages 140-144.
Crossref
Crossref
Melissa Bou-Jaoudeh, Angelina Mimoun, Sandrine Delignat, Ivan Peyron, Ladislas Capdevila, Victoria Daventure, Claire Deligne, Jordan D. Dimitrov, Olivier D. Christophe, Cécile V. Denis, Peter J. Lenting, Valérie Proulle & Sébastien Lacroix-Desmazes. (2023) Imlifidase, a new option to optimize the management of patients with hemophilia A on emicizumab. Journal of Thrombosis and Haemostasis.
Crossref
Crossref
Linghui Qian, Xuefen Lin, Xue Gao, Rizwan Ullah Khan, Jia-Yu Liao, Shubo Du, Jingyan Ge, Su Zeng & Shao Q. Yao. (2023) The Dawn of a New Era: Targeting the “Undruggables” with Antibody-Based Therapeutics. Chemical Reviews 123:12, pages 7782-7853.
Crossref
Crossref
Wilhelmus E. A. de Witte, Lindsay B. Avery, Brian C. Mackness, Tom Van Bogaert, Anna Park & Maria Laura Sargentini-Maier. (2023) Mechanistic incorporation of FcRn binding in plasma and endosomes in a whole body PBPK model for large molecules. Journal of Pharmacokinetics and Pharmacodynamics 50:3, pages 229-241.
Crossref
Crossref
Gibran Nasir & Photini Sinnis. (2023) Transport of antibody into the skin is only partially dependent upon the neonatal Fc-receptor. PLOS ONE 18:4, pages e0273960.
Crossref
Crossref
Christophe Dumet, Martine Pugnière, Corinne Henriquet, Valérie Gouilleux-Gruart, Anne Poupon & Hervé Watier. (2023) Harnessing Fc/FcRn Affinity Data from Patents with Different Machine Learning Methods. International Journal of Molecular Sciences 24:6, pages 5724.
Crossref
Crossref
Tomohiro Fujii, Yutaka Matsuda, Takuya Seki, Natsuki Shikida, Yusuke Iwai, Yuri Ooba, Kazutoshi Takahashi, Muneki Isokawa, Sayaka Kawaguchi, Noriko Hatada, Tomohiro Watanabe, Rika Takasugi, Akira Nakayama, Kazutaka Shimbo, Brian A. Mendelsohn, Tatsuya Okuzumi & Kei Yamada. (2023) AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody–Drug Conjugate Production. Bioconjugate Chemistry.
Crossref
Crossref
Tolulope A. Aweda, Shih-Hsun Cheng, Stephen C. Lenhard, Armin Sepp, Tinamarie Skedzielewski, Chih-Yang Hsu, Shelly Marshall, Heather Haag, Jonathan Kehler, Prabhas Jagdale, Alessia Peter, Michael A. Schmid, Andrew Gehman, Minh Doan, Andrew P. Mayer, Peter Gorycki, Marie Fanget, Christophe Colas, Brenda Smith, Curtis C. Maier & Hasan Alsaid. (2022) In vivo biodistribution and pharmacokinetics of sotrovimab, a SARS-CoV-2 monoclonal antibody, in healthy cynomolgus monkeys. European Journal of Nuclear Medicine and Molecular Imaging 50:3, pages 667-678.
Crossref
Crossref
Neil M Bodie, Rina Hashimoto, David Connolly, Jennifer Chu, Kazuo Takayama & Bruce D Uhal. (2023) Design of a chimeric ACE-2/Fc-silent fusion protein with ultrahigh affinity and neutralizing capacity for SARS-CoV-2 variants. Antibody Therapeutics 6:1, pages 59-74.
Crossref
Crossref
Abdulrahman Theyab, Khalaf F. Alsharif, Khalid J. Alzahrani, Atif Abdulwahab A. Oyouni, Yousef MohammedRabaa Hawsawi, Mohammad Algahtani, Saad Alghamdi & Amal F. Alshammary. (2023) New insight into strategies used to develop long-acting G-CSF biologics for neutropenia therapy. Frontiers in Oncology 12.
Crossref
Crossref
Yoshika IwataHitoshi Katada, Momoko Okuda, Yoshiaki DoiTim Jang Ching, Asako HaradaAkira TakeiriMasaki HondaMasayuki Mishima. (2023) Preclinical <i>in vitro</i> evaluation of immune suppression induced by GYM329, Fc-engineered sweeping antibody. The Journal of Toxicological Sciences 48:7, pages 399-409.
Crossref
Crossref
Michael W. Leach & Katherine Hammerman. 2023. Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 2 : Safety Assessment Environmental Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 2 : Safety Assessment Environmental Toxicologic Pathology
175
230
.
Adem Hadjabdelhafid-Parisien, Sebastian Bitsch, Arturo Macarrón Palacios, Lukas Deweid, Harald Kolmar & Joelle N. Pelletier. (2022) Tag-free, specific conjugation of glycosylated IgG1 antibodies using microbial transglutaminase. RSC Advances 12:52, pages 33510-33515.
Crossref
Crossref
Matthew Dent, Katarina L. Mayer, Noel Verjan Garcia, Haixun Guo, Hiroyuki Kajiura, Kazuhito Fujiyama & Nobuyuki Matoba. (2022)
Impact of glycoengineering and antidrug antibodies on the anticancer activity of a plant‐made
lectin‐Fc
fusion protein
. Plant Biotechnology Journal 20:11, pages 2217-2230.
Crossref
Crossref
Sanghwan Ko, Sora Park, Myung Ho Sohn, Migyeong Jo, Byoung Joon Ko, Jung-Hyun Na, Hojin Yoo, Ae Lee Jeong, Kyungsoo Ha, Ju Rang Woo, Chungsu Lim, Jung Hyu Shin, Dohyun Lee, So-Young Choi & Sang Taek Jung. (2022) An Fc variant with two mutations confers prolonged serum half-life and enhanced effector functions on IgG antibodies. Experimental & Molecular Medicine 54:11, pages 1850-1861.
Crossref
Crossref
Jong Won Lee, Jiwon Choi, Yeonho Choi, Kwangmeyung Kim, Yoosoo Yang, Sun Hwa Kim, Hong Yeol Yoon & Ick Chan Kwon. (2022) Molecularly engineered siRNA conjugates for tumor-targeted RNAi therapy. Journal of Controlled Release 351, pages 713-726.
Crossref
Crossref
Xiaoming Liu, Xiaohui Zhou, Aziz Ullah Noor, Xinyu Zhang, Chengyi Song & Huaichang Sun. (2022) Enhancing half-life and cytotoxicity of porcine respiratory and reproductive syndrome virus soluble receptors by taming their Fc domains. Veterinary Microbiology 273, pages 109526.
Crossref
Crossref
Helen Haixia Wu, Maureen Crames, Yangjie Wei, Dongmei Liu, Kristina Gueneva-Boucheva, Ikbae Son, Lee Frego, Fei Han, Rachel Kroe-Barrett, Andrew Nixon & Michael Marlow. (2022) Effect of the ADCC-Modulating Mutations and the Selection of Human IgG Isotypes on Physicochemical Properties of Fc. Journal of Pharmaceutical Sciences 111:9, pages 2411-2421.
Crossref
Crossref
Stella J. Berendam, Ashley N. Nelson, Bhrugu Yagnik, Ria Goswami, Tiffany M. Styles, Margaret A. Neja, Caroline T. Phan, Sedem Dankwa, Alliyah U. Byrd, Carolina Garrido, Rama R. Amara, Ann Chahroudi, Sallie R. Permar & Genevieve G. Fouda. (2022) Challenges and Opportunities of Therapies Targeting Early Life Immunity for Pediatric HIV Cure. Frontiers in Immunology 13.
Crossref
Crossref
Tobias Ruck, Falk Nimmerjahn, Heinz Wiendl & Jan D Lünemann. (2022) Next-generation antibody-based therapies in neurology. Brain 145:4, pages 1229-1241.
Crossref
Crossref
Kyung-Ho Jung, Jin Hee Lee, Mina Kim, Young Seok Cho & Kyung-Han Lee. (2022) 89Zr Immuno-PET Imaging of Tumor PD-1 Reveals That PMA Upregulates Lymphoma PD-1 through NFκB and JNK Signaling. Molecular Imaging 2022, pages 1-13.
Crossref
Crossref
Xujiao Ren, Ping Qian, Shudan Liu, Huanchun Chen & Xiangmin Li. (2021) Fc-Mediated E2-Dimer Subunit Vaccines of Atypical Porcine Pestivirus Induce Efficient Humoral and Cellular Immune Responses in Piglets. Viruses 13:12, pages 2443.
Crossref
Crossref
Peter Bloomingdale, Suruchi Bakshi, Christian Maass, Eline van Maanen, Cesar Pichardo-Almarza, Daniela Bumbaca Yadav, Piet van der Graaf & Nitin Mehrotra. (2021) Minimal brain PBPK model to support the preclinical and clinical development of antibody therapeutics for CNS diseases. Journal of Pharmacokinetics and Pharmacodynamics 48:6, pages 861-871.
Crossref
Crossref
Lei Wang, Lixiong Liu, Xiaoping Hong, Dongzhou Liu & Zeneng Cheng. (2021) Delanzomib, a Novel Proteasome Inhibitor, Combined With Adalimumab Drastically Ameliorates Collagen-Induced Arthritis in Rats by Improving and Prolonging the Anti-TNF-α Effect of Adalimumab. Frontiers in Pharmacology 12.
Crossref
Crossref
Lu Shan, Nydia Van Dyk, Nantaporn Haskins, Kimberly M. Cook, Kim L. Rosenthal, Ronit Mazor, Sonia Dragulin-Otto, Yu Jiang, Herren Wu, William F. Dall’Acqua, Martin J. Borrok, Melissa M. Damschroder & Vaheh Oganesyan. (2021) In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Communications Biology 4:1.
Crossref
Crossref
Kum-Kang So, Jeesun Chun, Nguyen Ngoc Luong, Hee-Won Seo & Dae-Hyuk Kim. (2021) Expression of an immunocomplex consisting of Fc fragment fused with a consensus dengue envelope domain III in Saccharomyces cerevisiae. Biotechnology Letters 43:9, pages 1895-1904.
Crossref
Crossref
Hui-Chen Chang Foreman, Andrew Frank & Timothy T. Stedman. (2021) Determination of variable region sequences from hybridoma immunoglobulins that target Mycobacterium tuberculosis virulence factors. PLOS ONE 16:8, pages e0256079.
Crossref
Crossref
Cláudia Azevedo, Soraia Pinto, Sopisa Benjakul, Jeannette Nilsen, Hélder A. Santos, Giovanni Traverso, Jan Terje Andersen & Bruno Sarmento. (2021) Prevention of diabetes-associated fibrosis: Strategies in FcRn-targeted nanosystems for oral drug delivery. Advanced Drug Delivery Reviews 175, pages 113778.
Crossref
Crossref
Elias Jabbour, Shilpa Paul & Hagop Kantarjian. (2021) The clinical development of antibody–drug conjugates — lessons from leukaemia. Nature Reviews Clinical Oncology 18:7, pages 418-433.
Crossref
Crossref
Nicholas R. Mahoney & Fatemeh Rajaii. (2021) Current Management of Thyroid Eye Disease. Current Treatment Options in Neurology 23:7.
Crossref
Crossref
Lisa Strasser, Amy Farrell, Jenny T. C. Ho, Kai Scheffler, Ken Cook, Patrick Pankert, Peter Mowlds, Rosa Viner, Barry L. Karger & Jonathan Bones. (2021) Proteomic Profiling of IgG1 Producing CHO Cells Using LC/LC-SPS-MS3: The Effects of Bioprocessing Conditions on Productivity and Product Quality. Frontiers in Bioengineering and Biotechnology 9.
Crossref
Crossref
Emanuele Andreano, Emanuele Nicastri, Ida Paciello, Piero Pileri, Noemi Manganaro, Giulia Piccini, Alessandro Manenti, Elisa Pantano, Anna Kabanova, Marco Troisi, Fabiola Vacca, Dario Cardamone, Concetta De Santi, Jonathan L. Torres, Gabriel Ozorowski, Linda Benincasa, Hyesun Jang, Cecilia Di Genova, Lorenzo Depau, Jlenia Brunetti, Chiara Agrati, Maria Rosaria Capobianchi, Concetta Castilletti, Arianna Emiliozzi, Massimiliano Fabbiani, Francesca Montagnani, Luisa Bracci, Giuseppe Sautto, Ted M. Ross, Emanuele Montomoli, Nigel Temperton, Andrew B. Ward, Claudia Sala, Giuseppe Ippolito & Rino Rappuoli. (2021) Extremely potent human monoclonal antibodies from COVID-19 convalescent patients. Cell 184:7, pages 1821-1835.e16.
Crossref
Crossref
Miho Nagayasu & Kazuhisa Ozeki. (2021) Combination of cassette-dosing and microsampling for reduced animal usage for antibody pharmacokinetics in cynomolgus monkeys, wild-type mice, and human FcRn transgenic mice. Pharmaceutical Research 38:4, pages 583-592.
Crossref
Crossref
Sanghwan Ko, Migyeong Jo & Sang Taek Jung. (2021) Recent Achievements and Challenges in Prolonging the Serum Half-Lives of Therapeutic IgG Antibodies Through Fc Engineering. BioDrugs 35:2, pages 147-157.
Crossref
Crossref
Claire I. Butré & Arnaud Delobel. 2021. Carbohydrate Analysis by Modern Liquid Phase Separation Techniques. Carbohydrate Analysis by Modern Liquid Phase Separation Techniques
761
814
.
Wibke Lembke & Mathias Locher. 2020. Regulatory Toxicology. Regulatory Toxicology
1
16
.
Wibke Lembke & Mathias Locher. 2021. Regulatory Toxicology. Regulatory Toxicology
83
98
.
Arnaud Delobel. 2021. Mass Spectrometry of Glycoproteins. Mass Spectrometry of Glycoproteins
1
21
.
Sofia Rossini, Rémi Noé, Victoria Daventure, Maxime Lecerf, Sune Justesen & Jordan D. Dimitrov. (2020) V Region of IgG Controls the Molecular Properties of the Binding Site for Neonatal Fc Receptor. The Journal of Immunology 205:10, pages 2850-2860.
Crossref
Crossref
Simone Ladel, Frank Maigler, Johannes Flamm, Patrick Schlossbauer, Alina Handl, Rebecca Hermann, Helena Herzog, Thomas Hummel, Boris Mizaikoff & Katharina Schindowski. (2020) Impact of Glycosylation and Species Origin on the Uptake and Permeation of IgGs through the Nasal Airway Mucosa. Pharmaceutics 12:11, pages 1014.
Crossref
Crossref
Xiaosheng Liu, Wei Cao & Taisheng Li. (2020) High-Dose Intravenous Immunoglobulins in the Treatment of Severe Acute Viral Pneumonia: The Known Mechanisms and Clinical Effects. Frontiers in Immunology 11.
Crossref
Crossref
Mateusz Adam Krzyscik, Małgorzata Zakrzewska & Jacek Otlewski. (2020) Site-Specific, Stoichiometric-Controlled, PEGylated Conjugates of Fibroblast Growth Factor 2 (FGF2) with Hydrophilic Auristatin Y for Highly Selective Killing of Cancer Cells Overproducing Fibroblast Growth Factor Receptor 1 (FGFR1). Molecular Pharmaceutics 17:7, pages 2734-2748.
Crossref
Crossref
Angelina Mimoun, Sandrine Delignat, Ivan Peyron, Victoria Daventure, Maxime Lecerf, Jordan D. Dimitrov, Srinivas V. Kaveri, Jagadeesh Bayry & Sébastien Lacroix-Desmazes. (2020) Relevance of the Materno-Fetal Interface for the Induction of Antigen-Specific Immune Tolerance. Frontiers in Immunology 11.
Crossref
Crossref