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Human Vaccines & Immunotherapeutics Volume 11, 2015 - Issue 6
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Review

A paradigm shift: Cancer therapy with peptide-based B-cell epitopes and peptide immunotherapeutics targeting multiple solid tumor types: Emerging concepts and validation of combination immunotherapy

Pravin TP KaumayaDepartment of Obstetrics and Gynecology; The Ohio State University Wexner Medical Center; Columbus, OH, USA;Department of Microbiology; The Ohio State University; Columbus, OH, USA;James Cancer Hospital and Solove Research Institute and the Comprehensive Cancer Center; The Ohio State University; Columbus, OH, USACorrespondence[email protected]
Pages 1368-1386 | Received 31 Oct 2014, Accepted 26 Feb 2015, Published online: 18 Jun 2015

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Pravin T. P. Kaumaya, Linlin Guo, Jay Overholser, Manuel L. Penichet & Tanios Bekaii-Saab. (2020) Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vaccines (B-Vaxx) in a syngeneic mouse model. OncoImmunology 9:1.
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Mariela A. Moreno Ayala, Maria Florencia Gottardo, Antonela S. Asad, Camila Zuccato, Alejandro Nicola, Adriana Seilicovich & Marianela Candolfi. (2017) Immunotherapy for the treatment of breast cancer. Expert Opinion on Biological Therapy 17:7, pages 797-812.
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Articles from other publishers (13)

Jing-Jing Du, Zhenhong Su, Haoyi Yu, Sanhai Qin & Dongyuan Wang. (2023) From design to clinic: Engineered peptide nanomaterials for cancer immunotherapy. Frontiers in Chemistry 10.
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Ritika Luthra, Shreeja Datta & Arpita Roy. (2021) Role of Different Peptides for Cancer Immunotherapy. International Journal of Peptide Research and Therapeutics 27:4, pages 2777-2793.
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Muhammad Luqman Nordin, Abdin Shakirin Mohamad Norpi, Pei Yuen Ng, Khatijah Yusoff, Nadiah Abu, Kue Peng Lim & Fazren Azmi. (2021) HER2/neu-Based Peptide Vaccination-Pulsed with B-Cell Epitope Induced Efficient Prophylactic and Therapeutic Antitumor Activities in TUBO Breast Cancer Mice Model. Cancers 13:19, pages 4958.
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Jamie Wallis, Prateek Katti, Alexander M. Martin, Tom Hills, Leonard W. Seymour, Daniel P. Shenton & Robert C. Carlisle. (2020) A liposome-based cancer vaccine for a rapid and high-titre anti-ErbB-2 antibody response. European Journal of Pharmaceutical Sciences 152, pages 105456.
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Winfrey Pui Yee Hoo, Pui Yan Siak, Nur Aqlili Riana Alias, Jia Jia Wong, Ee Wern Tan, Adelene Ai-Lian Song, Raha Abdul Rahim & Lionel Lian Aun In. (2020) K-ras peptide mimotope induces a humoral immune response against G12V K-ras antigen in BALB/c mice. Asia Pacific Journal of Molecular Biology and Biotechnology, pages 22-35.
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Pravin TP Kaumaya. (2020) B-cell epitope peptide cancer vaccines: a new paradigm for combination immunotherapies with novel checkpoint peptide vaccine. Future Oncology.
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Priscilla S. Briquez, Sylvie Hauert, Alexandre de Titta, Laura T. Gray, Aaron T. Alpar, Melody A. Swartz & Jeffrey A. Hubbell. (2020) Engineering Targeting Materials for Therapeutic Cancer Vaccines. Frontiers in Bioengineering and Biotechnology 8.
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Fei Fei Guo & Jiu Wei Cui. (2019) The Role of Tumor-Infiltrating B Cells in Tumor Immunity. Journal of Oncology 2019, pages 1-9.
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Tanios Bekaii-Saab, Robert Wesolowski, Daniel H. Ahn, Christina Wu, Amir Mortazavi, Maryam Lustberg, Bhuvaneswari Ramaswamy, Jeffrey Fowler, Lai Wei, Jay Overholser & Pravin T.P. Kaumaya. (2019) Phase I Immunotherapy Trial with Two Chimeric HER-2 B-Cell Peptide Vaccines Emulsified in Montanide ISA 720VG and Nor-MDP Adjuvant in Patients with Advanced Solid Tumors. Clinical Cancer Research 25:12, pages 3495-3507.
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Naipeng CuiJianhong ShiChuanwei Yang. (2018) HER2-Based Immunotherapy for Breast Cancer. Cancer Biotherapy and Radiopharmaceuticals 33:5, pages 169-175.
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Dane A. Hayes, Dale A. Kunde, Robyn L. Taylor, Stephen B. Pyecroft, Sukhwinder Singh Sohal & Elizabeth T. Snow. (2017) ERBB3: A potential serum biomarker for early detection and therapeutic target for devil facial tumour 1 (DFT1). PLOS ONE 12:6, pages e0177919.
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P.T.P. Kaumaya & T. Bekaii-Saab. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 1 31 .
Jing-Zhang Wang, Yu-Hua Zhang, Xin-Hua Guo, Hong-Yan Zhang & Yuan Zhang. (2016) The double-edge role of B cells in mediating antitumor T-cell immunity: Pharmacological strategies for cancer immunotherapy. International Immunopharmacology 36, pages 73-85.
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