7,880
Views
63
CrossRef citations to date
0
Altmetric
Review

A conceptual review of rhodanine: current applications of antiviral drugs, anticancer and antimicrobial activities

, , , &
Pages 1132-1148 | Received 20 Oct 2018, Accepted 29 Dec 2018, Published online: 03 Apr 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Sumeer Ahmed, Ajmal R. Bhat, Aziz Kalilur Rahiman, Rajendra S. Dongre, Aso Hameed Hasan, Vidya Niranjan, Lavanya C, S. A. Sheikh, Joazaizulfazli Jamalis, Malika Berredjem & Sarkar M. A. Kawsar. (2023) Green synthesis, antibacterial and antifungal evaluation of new thiazolidine-2,4-dione derivatives: molecular dynamic simulation, POM study and identification of antitumor pharmacophore sites. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-17.
Read now
İbrahim Evren Kıbrız, Senem Akkoç, Yusuf Sert, Ümit Çay & Şevket Hakan Üngören. (2022) Synthesis, antiproliferative activity, molecular docking studies of hydrazone functionalised thioparabanic acid and rhodanine analogues. Phosphorus, Sulfur, and Silicon and the Related Elements 197:9, pages 918-926.
Read now
F. Matloubi Moghaddam, Bagher Aghamiri & Mahbod Jalalinik. (2022) A facile one-pot, four-component synthesis of (Z)-isomer of rhodanine-oxindole derivatives under environmentally benevolent conditions. Synthetic Communications 52:2, pages 175-184.
Read now

Articles from other publishers (60)

Martin Krátký, Karolína Nováčková, Katarína Svrčková, Markéta Švarcová & Šárka Štěpánková. (2023) New 3-amino-2-thioxothiazolidin-4-one-based inhibitors of acetyl- and butyryl-cholinesterase: synthesis and activity. Future Medicinal Chemistry.
Crossref
Zebabanu Khalifa, Rachana Upadhyay & Amit B. Patel. (2023) Arylidene and amino spacer‐linked rhodanine‐quinoline hybrids as upgraded antimicrobial agents. Chemical Biology & Drug Design 102:6, pages 1632-1642.
Crossref
Anna Kryshchyshyn-Dylevych, Danylo Kaminskyy & Roman Lesyk. (2023) In‐vitro antiviral screening of some thiopyranothiazoles. Chemico-Biological Interactions 386, pages 110738.
Crossref
Zainab A. Jabbar, Monther F. Mahdi & Basma M.Abd Razik. (2023) Synthesis, Characterization, ADME Study and Anti-proliferative evaluation against MCF-7 breast cancer cell line of new analog of a 4-aminophenyl quinazolinone derivative. Al Mustansiriyah Journal of Pharmaceutical Sciences 23:4, pages 411-428.
Crossref
Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Fatemeh Fallahi Nezhad, Mojtaba Binazadeh, Milad Dehdashtijahromi, Navid Omidifar, Yasamin Ghahramani, Chin Wei Lai, Wei-Hung Chiang & Ahmad Gholami. (2023) Innovative Metal-Organic Frameworks for Targeted Oral Cancer Therapy: A Review. Materials 16:13, pages 4685.
Crossref
Ayman M. Ibrahim, Mai E. Shoman, Mamdouh F. A. Mohamed, Alaa M. Hayallah & Gamal El‐Din A. Abuo‐Rahma. (2023) Chemistry and Applications of Functionalized 2,4‐Thiazolidinediones. European Journal of Organic Chemistry 26:19.
Crossref
Lin Chen & Wen‐Ya Jiao. (2023) Yb(OTf) 3 Anchored on Crosslinked Chitosan Microsphere: A Green Heterogenized Catalyst for the Synthesis of Bispiro‐Fused Heterocycles . European Journal of Organic Chemistry 26:19.
Crossref
Nadezhda P. Novichikhina, Alexander S. Shestakov, Svetlana M. Medvedeva, Anna M. Lagutina, Mikhail Yu. Krysin, Nadezhda A. Podoplelova, Mikhail A. Panteleev, Ivan S. Ilin, Alexey V. Sulimov, Anna S. Tashchilova, Vladimir B. Sulimov, Athina Geronikaki & Khidmet S. Shikhaliev. (2023) New Hybrid Tetrahydropyrrolo[3,2,1-ij]quinolin-1-ylidene-2-thioxothiazolidin-4-ones as New Inhibitors of Factor Xa and Factor XIa: Design, Synthesis, and In Silico and Experimental Evaluation. Molecules 28:9, pages 3851.
Crossref
Antara Sharma, Pranish Bomzan, Debadrita Roy, Abhijit Chhetri, Subhankar Choudhury, Narendra Nath Ghosh, Salim Ali, Puja BK, Shilpi Ghosh, Ankita Dutta, Anoop Kumar & Mahendra Nath Roy. (2023) Molecular Assembly of Rhodanine with Torus‐Shaped Cyclodextrins and Their Innovative Applications by Physicochemical Contrivance Simultaneously Optimized by Computational Study. ChemistrySelect 8:11.
Crossref
Meenakshi Duhan, Rahul Singh, Meena Devi, Jayant Sindhu, Parvin Kumar, Sudhir Kumar, Ramesh Kataria, Ashwani Kumar, Sohan Lal & Devender Singh. (2023) Thiazolidine-2,4-dione framework containing spiropyrrolidine-oxindole and 1,2,3-triazole scaffold: synthesis, in vitro α-amylase inhibition and in silico studies . New Journal of Chemistry 47:11, pages 5399-5412.
Crossref
Abhishek Chaurasyia, Pooja Chawla, Vikramdeep Monga & Gurpreet Singh. (2022) Rhodanine derivatives: An insight into the synthetic and medicinal perspectives as antimicrobial and antiviral agents. Chemical Biology & Drug Design 101:3, pages 500-549.
Crossref
Farrokhfar Valizadeh Harzand, Seyyed Navid Mousavi Nejad, Aziz Babapoor, Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Wei-Hung Chiang, Maria Giovanna Buonomenna & Chin Wei Lai. (2023) Recent Advances in Metal-Organic Framework (MOF) Asymmetric Membranes/Composites for Biomedical Applications. Symmetry 15:2, pages 403.
Crossref
Zhili Ren, Hui Ding, Ming Zhou, Nan Yang, Yanyong Liu & Piu Chan. (2022) 5-(4-Hydroxy-3-dimethoxybenzylidene)-thiazolidinone improves motor functions and exerts antioxidant potential in hemiparkinsonian rats. Behavioural Pharmacology 34:1, pages 68-77.
Crossref
Hayrani Eren BOSTANCI & Ulviye ACAR ÇEVİK. (2022) Benzimidazol-Tiyadiazol Türevlerinin Sentezi, Karakterizasyonu, Antioksidan ve Antikanser ÇalışmalarıSynthesis, Characterization, Antioxidant, and Anticancer Studies of Benzimidazole-Thiadiazole Derivatives. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi 9:2, pages 783-790.
Crossref
Rachana Upadhyay, Zebabanu Khalifa, Divyesh Patel & Amit B. Patel. (2022) Rhodanine‐Incorporated Indole Derivatives as Pharmacologically Vital Hybrids. ChemistrySelect 7:45.
Crossref
Yasamin Ghahramani, Marzieh Mokhberi, Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Fatemeh Fallahi Nezhad, Wei-Hung Chiang, Ahmad Gholami & Chin Wei Lai. (2022) Synergistically Enhancing the Therapeutic Effect on Cancer, via Asymmetric Bioinspired Materials. Molecules 27:23, pages 8543.
Crossref
Seyyed Mojtaba Mousavi, Gity Behbudi, Ahmad Gholami, Seyyed Alireza Hashemi, Zohre Mousavi Nejad, Sonia Bahrani, Wei-Hung Chiang, Lai Chin Wei & Navid Omidifar. (2022) Shape-controlled synthesis of zinc nanostructures mediating macromolecules for biomedical applications. Biomaterials Research 26:1.
Crossref
Ayşen IŞIK, Ulviye Acar Çevik, Ismail Çelik, Hayrani Eren Bostancı, Arzu Karayel, Gülsüm Gündoğdu, Ufuk Ince, Ahmet Koçak, Yusuf Özkay & Zafer Asım Kaplancıklı. (2022) Benzimidazole-hydrazone derivatives: Synthesis, in vitro anticancer, antimicrobial, antioxidant activities, in silico DFT and ADMET studies. Journal of Molecular Structure 1270, pages 133946.
Crossref
Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Sargol Mazraedoost, Wei-Hung Chiang, Khadije Yousefi, Omid Arjmand, Yasmin Ghahramani, Ahmad Gholami, Navid Omidifar, Nelson Pynadathu Rumjit, Marjan Salari & Asma Sadrmousavi-Dizaj. (2022) Anticancer, antimicrobial and biomedical features of polyoxometalate as advanced materials: A review study. Inorganic Chemistry Communications 146, pages 110074.
Crossref
Baijayantimala Swain, Abrar Khan, Priti Singh, Vaibhav S. Marde, Andrea Angeli, Krishna Kartheek Chinchilli, Venkata Madhavi Yaddanapudi, Simone Carradori, Claudiu T. Supuran & Mohammed Arifuddin. (2022) Design, Synthesis and Biological Assessment of Rhodanine-Linked Benzenesulfonamide Derivatives as Selective and Potent Human Carbonic Anhydrase Inhibitors. Molecules 27:22, pages 8028.
Crossref
Sina Yaghoubi, Aziz Babapoor, Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Chin Wei Lai & Wei-Hung Chiang. (2022) Recent Advances in Plasmonic Chemically Modified Bioactive Membrane Applications for the Removal of Water Pollution. Water 14:22, pages 3616.
Crossref
Consuelo B. Correa Sierra & Luis M. Schang. (2022) On the Sensitivity of the Virion Envelope to Lipid Peroxidation. Microbiology Spectrum 10:5.
Crossref
Ewa Żesławska, Waldemar Tejchman, Annamária Kincses, Gabriella Spengler, Wojciech Nitek, Grzegorz Żuchowski & Ewa Szymańska. (2022) 5-Arylidenerhodanines as P-gp Modulators: An Interesting Effect of the Carboxyl Group on ABCB1 Function in Multidrug-Resistant Cancer Cells. International Journal of Molecular Sciences 23:18, pages 10812.
Crossref
Ahmad Khairul Daniel bin Ahmad Kamar, Lim Ju Yin, Chin Tze Liang, Gan Tjin Fung & Vasudeva Rao Avupati. (2022) Rhodanine scaffold: A review of antidiabetic potential and structure–activity relationships (SAR). Medicine in Drug Discovery 15, pages 100131.
Crossref
Huiying Guo, Pengfei Zhang, Ronghui Zhao, Xue Meng, Hongmei Liu & Kuilin Deng. (2022) Aggregation-induced emission enhancement (AIEE) of polyethylenimine functionalized with 3-allylrhodanine and specific detection for Ag+ ions. Dyes and Pigments 205, pages 110562.
Crossref
Rui Li, Yuankun Wang & Tengfei Long. (2022) Efficient Isolation of Circulating Tumor Cells Using Ultra-Convenient Substrates Based on Self-Assembled Hollow MnO2 Nanoparticles. Coatings 12:8, pages 1214.
Crossref
Qing Han, Nan Wu, Yao-Yang Liu, Jing-Yu Zhang, Ru-Lei Zhang, Hui-Lin Li, Zhi-Yang Jiang, Jia-Xing Huang, Hong-Xia Duan & Qing Yang. (2022) Piperonyl-Tethered Rhodanine Derivatives Potently Inhibit Chitinolytic Enzymes of Ostrinia furnacalis . Journal of Agricultural and Food Chemistry 70:24, pages 7387-7399.
Crossref
Ewa Żesławska, Robert Zakrzewski, Arkadiusz Nowicki, Izabela Korona-Głowniak, Antonín Lyčka, Agnieszka Kania, Krzysztof Kazimierz Zborowski, Piotr Suder, Agnieszka Skórska-Stania & Waldemar Tejchman. (2022) Synthesis, Crystal Structures, Lipophilic Properties and Antimicrobial Activity of 5-Pyridylmethylidene-3-rhodanine-carboxyalkyl Acids Derivatives. Molecules 27:13, pages 3975.
Crossref
Jacek Szczepański, Helena Tuszewska & Nazar Trotsko. (2022) Anticancer Profile of Rhodanines: Structure–Activity Relationship (SAR) and Molecular Targets—A Review. Molecules 27:12, pages 3750.
Crossref
Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Masoomeh Yari Kalashgrani, Neralla Vijayakameswara Rao, Navid Omidifar, Wesley Wei-Wen Hsiao, Chin Wei Lai & Wei-Hung Chiang. (2022) Plasma-Enabled Smart Nanoexosome Platform as Emerging Immunopathogenesis for Clinical Viral Infection. Pharmaceutics 14:5, pages 1054.
Crossref
Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Masoomeh Yari Kalashgrani, Ahmad Gholami, Navid Omidifar, Aziz Babapoor, Neralla Vijayakameswara Rao & Wei-Hung Chiang. (2022) Recent Advances in Plasma-Engineered Polymers for Biomarker-Based Viral Detection and Highly Multiplexed Analysis. Biosensors 12:5, pages 286.
Crossref
Pedro Silvino Pereira, Adrielle Rodrigues Costa, Thalyta Julyanne Silva de Oliveira, Carlos Vinícius Barros Oliveira, Maria do Carmo Alves de Lima, Jamerson Ferreira de Oliveira, Bonglee Kim, Henrique D. M. Coutinho, Antonia Eliene Duarte, Jean Paul Kamdem & Teresinha Gonçalves da Silva. (2022) Neurolocomotor Behavior and Oxidative Stress Markers of Thiazole and Thiazolidinedione Derivatives against Nauphoeta cinerea. Antioxidants 11:2, pages 420.
Crossref
Agustin Garcia-Caballero, Vinicius M. Gadotti, Md Yousof Ali, Chris Bladen, Eder Gambeta, Jeffrey F. Van Humbeck, Justin L. MacCallum & Gerald W. Zamponi. (2022) A Synthetically Accessible Small-Molecule Inhibitor of USP5-Cav3.2 Calcium Channel Interactions with Analgesic Properties. ACS Chemical Neuroscience 13:4, pages 524-536.
Crossref
Fatma A. Mohamed, Shaban Elkhabiry, Ismail A. Ismail & Attia O. Attia. (2022) Synthesis, Application and Antimicrobial Activity of New Acid Dyes Based on 3-Amino-2-thioxo-4-thiazolidinone Nucleus on Wool and Silk Fabrics. Current Organic Synthesis 19:1, pages 166-176.
Crossref
Kalpana Tilekar, Onkar Shelke, Neha Upadhyay, Antonio Lavecchia & C S Ramaa. (2022) Current status and future prospects of molecular hybrids with thiazolidinedione (TZD) scaffold in anticancer drug discovery. Journal of Molecular Structure 1250, pages 131767.
Crossref
Valentina Gentili, Giulia Turrin, Paolo Marchetti, Sabrina Rizzo, Giovanna Schiuma, Silvia Beltrami, Virginia Cristofori, Davide Illuminati, Greta Compagnin, Claudio Trapella, Roberta Rizzo, Daria Bortolotti & Anna Fantinati. (2022) Synthesis and biological evaluation of novel rhodanine-based structures with antiviral activity towards HHV-6 virus. Bioorganic Chemistry 119, pages 105518.
Crossref
Lim Ju Yin, Ahmad Khairul Daniel bin Ahmad Kamar, Gan Tjin Fung, Chin Tze Liang & Vasudeva Rao Avupati. (2022) Review of anticancer potentials and structure-activity relationships (SAR) of rhodanine derivatives. Biomedicine & Pharmacotherapy 145, pages 112406.
Crossref
Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Khadije Yousefi, Ahmad Gholami, Sonia Bahrani, Wei-Hung Chiang, Chin Wei Lai & Ali Alizadeh. 2022. Encyclopedia of Energy Storage. Encyclopedia of Energy Storage 692 702 .
Kritika Laxmikeshav, Pooja Kumari & Nagula Shankaraiah. (2021) Expedition of sulfur‐containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update. Medicinal Research Reviews 42:1, pages 513-575.
Crossref
Ricardo Torán, Rubén Miguélez, Amparo Sanz‐Marco, Carlos Vila, José R. Pedro & Gonzalo Blay. (2021) Asymmetric Addition and Cycloaddition Reactions with Ylidene‐Five‐Membered Heterocycles. Advanced Synthesis & Catalysis 363:23, pages 5196-5234.
Crossref
Assem Barakat, Matti Haukka, Saied M. Soliman, M. Ali, Abdullah Mohammed Al-Majid, Ayman El-Faham & Luis R. Domingo. (2021) Straightforward Regio- and Diastereoselective Synthesis, Molecular Structure, Intermolecular Interactions and Mechanistic Study of Spirooxindole-Engrafted Rhodanine Analogs. Molecules 26:23, pages 7276.
Crossref
Mao Fan, Bin Zhang, Li Fan, Feng Chen & Qiang Fu. (2021) Adsorbability of Modified PBS Nanofiber Membrane to Heavy Metal Ions and Dyes. Journal of Polymers and the Environment 29:9, pages 3029-3039.
Crossref
Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Navid Omidifar, Maryam Zarei, Sonia Bahrani, Khadije Yousefi, Wei-Hung Chiang & Aziz Babapoor. (2021) Bioinorganic Synthesis of Polyrhodanine Stabilized Fe3O4/Graphene Oxide in Microbial Supernatant Media for Anticancer and Antibacterial Applications. Bioinorganic Chemistry and Applications 2021, pages 1-12.
Crossref
Seyyed Mojtaba Mousavi, Maryam Zarei, Seyyed Alireza Hashemi, Wei‐Hung Chiang, Chin Wei Lai & Sonia Bahrani. 2021. Self‐Healing Smart Materials and Allied Applications. Self‐Healing Smart Materials and Allied Applications 475 493 .
Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Najmeh Parvin, Chin Wei Lai, Sonia Bahrani, Wei‐Hung Chiang & Sargol Mazraedoost. 2021. Flexible Supercapacitor Nanoarchitectonics. Flexible Supercapacitor Nanoarchitectonics 95 141 .
M. E. A. Elasasy, D. H. Elnaggar, N. A. Abdel Hafez, M. E. Azab, A. E. Amr, M. M. Omran & A. M. Mohamed. (2021) Synthesis and Antiproliferative Activity of Novel Hydrazono Thiazolidene and Thiazole Derivatives Bearing Rhodanine Moiety. Russian Journal of General Chemistry 91:5, pages 915-925.
Crossref
Eleonora-Mihaela Ungureanu, Mariana Popescu (Apostoiu)Georgiana-Luiza Tatu (Arnold)Liviu Birzan, Raluca Isopescu, Gabriela Stanciu & George-Octavian Buica. (2021) Electrochemical Comparison on New (Z)-5-(Azulen-1-Ylmethylene)-2-Thioxo-Thiazolidin-4-Ones. Symmetry 13:4, pages 588.
Crossref
Arif Mermer. (2021) The Importance of Rhodanine Scaffold in Medicinal Chemistry: A Comprehensive Overview. Mini-Reviews in Medicinal Chemistry 21:6, pages 738-789.
Crossref
Pedro Brandão, Carolina S. Marques, Elisabete P. Carreiro, M. Pineiro & Anthony J. Burke. (2021) Engaging Isatins in Multicomponent Reactions (MCRs) – Easy Access to Structural Diversity. The Chemical Record 21:4, pages 924-1037.
Crossref
Yogita Bansal, Richa Minhas, Ankit Singhal, Radhey Krishan Arora & Gulshan Bansal. (2021) Benzimidazole: A Multifacted Nucelus for Anticancer Agents. Current Organic Chemistry 25:6, pages 669-694.
Crossref
Mridula Guin, Kamal Rautela, R.A. Roopa, C.S. Shantharam & S. Begam Elavarasi. (2021) Hydrogen bonded complexes of rhodanine with H2X/CH3XH (X = O, S, Se). Computational and Theoretical Chemistry 1196, pages 113134.
Crossref
Chaima Boureghda, Raouf Boulcina, Vincent Dorcet, Fabienne Berrée, Bertrand Carboni & Abdelmadjid Debache. (2021) Facile synthesis of 5-arylidene rhodanine derivatives using Na2SO3 as an eco-friendly catalyst. Access to 2-mercapto-3-aryl-acrylic acids and a benzoxaborole derivative. Tetrahedron Letters 62, pages 152690.
Crossref
Amani Toumi, Sarra Boudriga, Khaled Hamden, Mansour Sobeh, Mohammed Cheurfa, Moheddine Askri, Michael Knorr, Carsten Strohmann & Lukas Brieger. (2021) Synthesis, antidiabetic activity and molecular docking study of rhodanine-substitued spirooxindole pyrrolidine derivatives as novel α-amylase inhibitors. Bioorganic Chemistry 106, pages 104507.
Crossref
Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Maryam Zarei, Ahmad Gholami, Chin Wei Lai, Wei Hung Chiang, Navid Omidifar, Sonia Bahrani & Sargol Mazraedoost. (2020) Recent Progress in Chemical Composition, Production, and Pharmaceutical Effects of Kombucha Beverage: A Complementary and Alternative Medicine. Evidence-Based Complementary and Alternative Medicine 2020, pages 1-14.
Crossref
Najmeh Parvin, Aziz Babapoor, Ali Nematollahzadeh & Seyyed Mojtaba Mousavi. (2020) Removal of phenol and β-naphthol from aqueous solution by decorated graphene oxide with magnetic iron for modified polyrhodanine as nanocomposite adsorbents: Kinetic, equilibrium and thermodynamic studies. Reactive and Functional Polymers 156, pages 104718.
Crossref
Seyyed Mojtaba Mousavi, Maryam Zarei, Seyyed Alireza Hashemi, Seeram Ramakrishna, Wei-Hung Chiang, Chin Wei Lai, Ahmad Gholami, Navid Omidifar & Mansoureh Shokripour. (2020) Asymmetric Membranes: A Potential Scaffold for Wound Healing Applications. Symmetry 12:7, pages 1100.
Crossref
Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Maryam Zarei, Sonia Bahrani, Amir Savardashtaki, Hossein Esmaeili, Chin Wei Lai, Sargol Mazraedoost, Mohsen Abassi & Bahman Ramavandi. (2020) Data on cytotoxic and antibacterial activity of synthesized Fe3O4 nanoparticles using Malva sylvestris. Data in Brief 28, pages 104929.
Crossref
Heba Kamal Abd El-Mawgoud. (2019) Synthesis, <i>in-Vitro</i> Cytotoxicity and Antimicrobial Evaluations of Some Novel Thiazole Based Heterocycles. Chemical and Pharmaceutical Bulletin 67:12, pages 1314-1323.
Crossref
Saurabh Loharch & Raman Parkesh. (2019) Epigenetic drug discovery: systematic assessment of chemical space. Future Medicinal Chemistry 11:21, pages 2803-2819.
Crossref
Mahamadhanif S. Shaikh, Ashish M. Kanhed, Balakumar Chandrasekaran, Mahesh B. Palkar, Nikhil Agrawal, Christian Lherbet, Girish A. Hampannavar & Rajshekhar Karpoormath. (2019) Discovery of novel N-methyl carbazole tethered rhodanine derivatives as direct inhibitors of Mycobacterium tuberculosis InhA. Bioorganic & Medicinal Chemistry Letters 29:16, pages 2338-2344.
Crossref