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Emerging Microbes & Infections Volume 11, 2022 - Issue 1
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Antimicrobial Agents

Cell membrane-anchored anti-HIV single-chain antibodies and bifunctional inhibitors targeting the gp41 fusion protein: new strategies for HIV gene therapy

Yue Chena NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China;b Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaView further author information
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Hongliang Jina NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China;b Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaCorrespondence[email protected]
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Xiaoran Tanga NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China;b Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaView further author information
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Li Lia NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaView further author information
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Xiuzhu Genga NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China;b Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaView further author information
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Yuanmei Zhua NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China;b Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-4515-6864View further author information
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Huihui Chonga NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China;b Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaView further author information
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Yuxian Hea NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China;b Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaCorrespondence[email protected]
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Pages 30-49 | Received 16 Jun 2021, Accepted 23 Nov 2021, Published online: 21 Dec 2021

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Xin Yao, Qingyu Wang, Changge Han, Jiaojiao Nie, Yaotian Chang, Lipeng Xu, Bingya Wu, Jingtian Yan, Zhiyuan Chen, Wei Kong, Yuhua Shi & Yaming Shan. (2023) Combined Nano-Vector Mediated-Transfer to Suppress HIV-1 Infection with Targeted Antibodies in-vitro. International Journal of Nanomedicine 18, pages 4635-4645.
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Hui-Yu Wu, Chia-Jung Kuo, Chia-Huei Chou, Mao-Wang Ho, Chyi-Liang Chen, Tsui-Shan Hsu, Ying-Chu Chen, Chuan Chiang-Ni, Yi-Ywan M. Chen, Cheng-Hsun Chiu & Chih-Ho Lai. (2023) Clostridium innocuum, an emerging pathogen that induces lipid raft-mediated cytotoxicity. Virulence 14:1.
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Articles from other publishers (4)

Fu-Sheng Wang & Linqi Zhang. (2024) The Fourth Symposium of Grand Challenges on HIV (2023.12.28). Infectious Diseases & Immunity 4:2, pages 96-98.
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Yani Gong & Yuxian He. (2023) Cell membrane anchoring strategies for HIV gene therapy. Cellular & Molecular Immunology 20:6, pages 683-685.
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Sara Insausti, Miguel Garcia-Porras, Johana Torralba, Izaskun Morillo, Ander Ramos-Caballero, Igor de la Arada, Beatriz Apellaniz, Jose M. M. Caaveiro, Pablo Carravilla, Christian Eggeling, Edurne Rujas & Jose L. Nieva. (2022) Functional Delineation of a Protein–Membrane Interaction Hotspot Site on the HIV-1 Neutralizing Antibody 10E8. International Journal of Molecular Sciences 23:18, pages 10767.
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Hongxia Yan, Tong Wu, Yue Chen, Hongliang Jin, Li Li, Yuanmei Zhu, Huihui Chong & Yuxian He. (2022) Design of a Bispecific HIV Entry Inhibitor Targeting the Cell Receptor CD4 and Viral Fusion Protein Gp41. Frontiers in Cellular and Infection Microbiology 12.
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