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Journal of Asthma Volume 42, 2005 - Issue 4
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Original Article

Hydrofluoroalkane-134A Beclomethasone or Chlorofluorocarbon Fluticasone: Effect on Small Airways in Poorly Controlled Asthma

Torpong Thongngarm Division of Allergy and Clinical Immunology, Department of Medicine, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, ColoradoUSA
, M.D.,
Philip E Silkoff Department of Medicine, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, ColoradoUSA
, M.D.,
William S Kossack Division of Biostatistics, National Jewish Medical and Research Center, Denver, ColoradoUSA
, M.S. &
Harold S Nelson Division of Allergy and Clinical Immunology, Department of Medicine, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, ColoradoUSACorrespondence[email protected]
, M.D.
Pages 257-263 | Published online: 02 Jul 2009

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István Ivancsó, Renáta Böcskei, Veronika Müller & Lilla Tamási. (2013) Extrafine inhaled corticosteroid therapy in the control of asthma. Journal of Asthma and Allergy 6, pages 69-80.
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Ruediger Nave & Helgert Mueller. (2013) From inhaler to lung: clinical implications of the formulations of ciclesonide and other inhaled corticosteroids. International Journal of General Medicine 6, pages 99-107.
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Nicola Scichilone, Adele Contino, Giovanni Battista Figlioli, Giuseppe Paglino & Vincenzo Bellia. (2010) Patient perspectives in the management of asthma: improving patient outcomes through critical selection of treatment options. Patient Preference and Adherence 4, pages 17-23.
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Articles from other publishers (35)

Luigino CALZETTA, Marina AIELLO, Annalisa FRIZZELLI, Giuseppina BERTORELLI & Alfredo CHETTA. (2022) Small airways in asthma: from bench-to-bedside. Minerva Medica 113:1.
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Dylan Vance, Ghiath Alnouri, William Valentino, Daniel Eichorn, Pankti Acharya & Robert T. Sataloff. (2021) Effects of Particle Size of Inhaled Corticosteroid on the Voice. Journal of Voice 35:3, pages 455-457.
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Céline El Baou, Rachael L. Di Santostefano, Rafael Alfonso-Cristancho, Elizabeth A Suarez, David Stempel, Mark L Everard & Neil Barnes. (2017) Effect of inhaled corticosteroid particle size on asthma efficacy and safety outcomes: a systematic literature review and meta-analysis. BMC Pulmonary Medicine 17:1.
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Dirkje S. Postma, Alan Kaplan, Joan B. Soriano, Jonathon Grigg, Theresa W. Guilbert, Wim van Aalderen, Nicolas Roche, Anne Burden, Elizabeth V. Hillyer, Elliot Israel & David B. Price. (2017) Cohort Analysis of Exacerbation Rates in Adolescent and Adult Patients Initiating Inhaled Corticosteroids for Asthma: Different Dose–Response Profile by Particle Size. Pulmonary Therapy 3:1, pages 113-124.
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Jatinder Kaur Mukker, Ravi Shankar Prasad Singh & Hartmut Derendorf. (2016) Ciclesonide: A Pro-Soft Drug Approach for Mitigation of Side Effects of Inhaled Corticosteroids. Journal of Pharmaceutical Sciences 105:9, pages 2509-2514.
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David Hodgson, John Anderson, Catherine Reynolds, Garry Meakin, Helen Bailey, Ian Pavord, Dominick Shaw & Tim Harrison. (2015) A randomised controlled trial of small particle inhaled steroids in refractory eosinophilic asthma (SPIRA). Thorax 70:6, pages 559-565.
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Brian Lipworth, Arvind Manoharan & William Anderson. (2014) Unlocking the quiet zone: the small airway asthma phenotype. The Lancet Respiratory Medicine 2:6, pages 497-506.
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David Price, Iain Small, John Haughney, Dermot Ryan, Kevin Gruffydd-Jones, Federico Lavorini, Tim Harris, Annie Burden, Jeremy Brockman, Christine King & Alberto Papi. (2013) Clinical and cost effectiveness of switching asthma patients from fluticasone-salmeterol to extra-fine particle beclometasone-formoterol: a retrospective matched observational study of real-world patients. Primary Care Respiratory Journal 22:4, pages 439-448.
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M. van den Berge, N. H. T. ten Hacken, E. van der Wiel & D. S. Postma. (2012) Treatment of the bronchial tree from beginning to end: targeting small airway inflammation in asthma. Allergy 68:1, pages 16-26.
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Nemr Eid & Ronald Morton. (2011) Lung function changes in asthmatic children treated with HFA‐BDP. Pediatric Pulmonology 46:9, pages 837-841.
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Charlotte Suppli Ulrik & Peter Lange. (2011) Targeting small airways in asthma: improvement in clinical benefit?. The Clinical Respiratory Journal 5:3, pages 125-130.
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Maarten van den Berge, Nick H.T. ten Hacken, Judith Cohen, W. Rob Douma & Dirkje S. Postma. (2011) Small Airway Disease in Asthma and COPD. Chest 139:2, pages 412-423.
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Alfredo de Diego Damiá & José María Vega Chicote. (2011) Abordaje terapéutico de la vía aérea pequeña en el asma. Archivos de Bronconeumología 47, pages 27-31.
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David Price, Richard J. Martin, Neil Barnes, Paul Dorinsky, Elliot Israel, Nicolas Roche, Alison Chisholm, Elizabeth V. Hillyer, Linda Kemp, Amanda J. Lee, Julie von Ziegenweidt & Gene Colice. (2010) Prescribing practices and asthma control with hydrofluoroalkane-beclomethasone and fluticasone: A real-world observational study. Journal of Allergy and Clinical Immunology 126:3, pages 511-518.e10.
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N. Scichilone, S. Battaglia, C. Sorino, G. Paglino, L. Martino, A. Paternò, R. Santagata, M. Spatafora, G. Nicolini & V. Bellia. (2010) Effects of extra‐fine inhaled beclomethasone/formoterol on both large and small airways in asthma. Allergy 65:7, pages 897-902.
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Rüdiger Nave. (2010) Determination of lung deposition following inhalation of ciclesonide using different bioanalytical procedures. Bioanalysis 2:4, pages 807-814.
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Chet Leach, Gene L. Colice & Allan Luskin. (2009) Particle size of inhaled corticosteroids: Does it matter?. Journal of Allergy and Clinical Immunology 124:6, pages S88-S93.
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N. Scichilone, S. Battaglia, D. Olivieri & V. Bellia. (2009) The role of small airways in monitoring the response to asthma treatment: what is beyond FEV 1 ? . Allergy 64:11, pages 1563-1569.
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P.-R. Burgel, I. Frachon, A. Didier & D. Dusser. (2009) Les traitements ciblant les voies aériennes distales dans l’asthme : analyse des études cliniques. Revue des Maladies Respiratoires 26:8, pages 859-866.
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Masafumi Yamaguchi, Akio Niimi, Tetsuya Ueda, Masaya Takemura, Hirofumi Matsuoka, Makiko Jinnai, Kojiro Otsuka, Tsuyoshi Oguma, Tomoshi Takeda, Isao Ito, Hisako Matsumoto, Toyohiro Hirai, Kazuo Chin & Michiaki Mishima. (2009) Effect of inhaled corticosteroids on small airways in asthma: Investigation using impulse oscillometry. Pulmonary Pharmacology & Therapeutics 22:4, pages 326-332.
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Maureen J. Lage, Gary N. Gross, Corrine Brewster & Anthony Spalitto. (2009) Outcomes and costs of patients with persistent asthma treated with beclomethasone dipropionate hydrofluoroalkane or fluticasone propionate. Advances in Therapy 26:8, pages 762-775.
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Rüdiger Nave. (2009) Clinical Pharmacokinetic and Pharmacodynamic Profile of Inhaled Ciclesonide. Clinical Pharmacokinetics 48:4, pages 243-252.
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G. Garcia, T. Perez & B. Mahut. (2009) Épreuves fonctionnelles respiratoires et évaluation des voies aériennes distales dans l’asthme. Revue des Maladies Respiratoires 26:4, pages 395-406.
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H William Kelly. (2009) Comparison of Inhaled Corticosteroids: An Update. Annals of Pharmacotherapy 43:3, pages 519-527.
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Stephen J. DeCanio & Catherine S. Norman. (2007) Economics of “essential use exemptions” for metered-dose inhalers under the Montreal Protocol. Journal of Environmental Management 85:1, pages 1-8.
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Hartmut Derendorf. (2007) Pharmacokinetic and Pharmacodynamic Properties of Inhaled Ciclesonide. The Journal of Clinical Pharmacology 47:6, pages 782-789.
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José-Manuel Tunon-de-Lara, François Laurent, Violaine Giraud, Thierry Perez, Bernard Aguilaniu, Houari Meziane, Armelle Basset-Merle & Pascal Chanez. (2007) Air trapping in mild and moderate asthma: Effect of inhaled corticosteroids. Journal of Allergy and Clinical Immunology 119:3, pages 583-590.
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A. A. Visel, V. N. Seliverstov, I. Yu. Visel, V. A. Sergeev & N. M. Rakhmatullina. (2007) Clinical equivalency of Beclasone Eco Easi Breathe and Flixotide via MDI in asthma patients. PULMONOLOGIYA:1, pages 74-81.
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Günther Hochhaus. (2007) Pharmacokinetic and pharmacodynamic properties important for inhaled corticosteroids. Annals of Allergy, Asthma & Immunology 98:2, pages S7-S15.
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Leonard Bielory. (2007) In search of the perfect steroid. Annals of Allergy, Asthma & Immunology 98:2, pages S1-S6.
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Tanya Gulliver, Ronald Morton & Nemr Eid. (2007) Inhaled Corticosteroids in Children with Asthma. Pediatric Drugs 9:3, pages 185-194.
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Gene L. Colice. (2006) Small airway disease: A riddle wrapped in a mystery inside an enigma. Journal of Allergy and Clinical Immunology 118:2, pages 337-339.
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Sylvia Verbanck, Daniël Schuermans, Manuel Paiva & Walter Vincken. (2006) The functional benefit of anti-inflammatory aerosols in the lung periphery. Journal of Allergy and Clinical Immunology 118:2, pages 340-346.
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Eli O. Meltzer & Hartmut Derendorf. (2006) The systemic safety of inhaled corticosteroid therapy: a focus on ciclesonide. Annals of Allergy, Asthma & Immunology 97:2, pages 149-157.
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. (2006) Current World Literature. Current Opinion in Allergy & Clinical Immunology 6:1, pages 67-76.
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