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Pharmaceutical Development and Technology Volume 6, 2001 - Issue 1
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Research Article

A Comparison of Reflectance and Transmittance Near-Infrared Spectroscopic Techniques in Determining Drug Content in Intact Tablets

Shilpa S. Thosar Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, Memphis, TN, U.S.A.
,
Reba A. Forbess Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, Memphis, TN, U.S.A.
,
Nkere K. Ebube Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, Memphis, TN, U.S.A.
,
Yixin Chen Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, Memphis, TN, U.S.A.
,
Ronald L. Rubinovitz Foss NIR Systems, Inc., Silver Spring, MD, U.S.A.
,
Mark S. Kemper Foss NIR Systems, Inc., Silver Spring, MD, U.S.A.
,
George E. Reier
,
Thomas A. Wheatley
&
Atul J. Shukla Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, Memphis, TN, U.S.A.; Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, 26 South Dunlap, 214 Feurt Building, Memphis, TN, 38163, U.S.A.
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Pages 19-29 | Received 31 Jul 1998, Accepted 09 Apr 2000, Published online: 25 Jan 2001

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M. Donoso & E.S. Ghaly. (2006) Use of Near-Infrared for Quantitative Measurement of Viscosity and Concentration of Active Ingredient in Pharmaceutical Gel. Pharmaceutical Development and Technology 11:3, pages 389-397.
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Articles from other publishers (27)

Michał Meisner, Piotr Duda, Beata Szulc-Musioł & Beata Sarecka-Hujar. (2023) Characteristics of Commercial Effervescent Tablets Using Selected Pharmacopeial and Novel Analytical Methods. Applied Sciences 13:5, pages 3171.
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Beata Sarecka-Hujar, Beata Szulc-Musioł, Michał Meisner & Piotr Duda. (2022) The Use of Novel, Rapid Analytical Tools in the Assessment of the Stability of Tablets—A Pilot Analysis of Expired and Unexpired Tablets Containing Nifuroxazide. Processes 10:10, pages 1934.
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Masoom Raza Siddiqui, Zeid A. AlOthman & Nafisur Rahman. (2017) Analytical techniques in pharmaceutical analysis: A review. Arabian Journal of Chemistry 10, pages S1409-S1421.
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Solveig Warnecke, Åsmund Rinnan, Morten Allesø & Soren B. Engelsen. (2015) Fluorescence Spectroscopy in Process Analytical Technology (PAT): Simultaneous Quantification of Two Active Pharmaceutical Ingredients in a Tablet Formulation. Applied Spectroscopy 69:3, pages 323-331.
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Daitaro Ishikawa, Takuma Genkawa, Kodai Murayama, Makoto Komiyama & Yukihiro Ozaki. (2014) Feasibility Study of Diffuse Reflectance and Transmittance near Infrared Spectroscopy for Rapid Analysis of Ascorbic Acid Concentration in Bilayer Tablets Using a High-Speed Polychromator-Type Spectrometer. Journal of Near Infrared Spectroscopy 22:3, pages 189-197.
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Nicola Kellichan, Alison Nordon, Pavel Matousek, David Littlejohn & Gary McGeorge. (2014) Variation in the Transmission Near-Infrared Signal with Depth in Turbid Media. Applied Spectroscopy 68:3, pages 383-387.
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Jinah Lee, Pham Khac Duy, Jihye Yoon & Hoeil Chung. (2014) Acquisition of reproducible transmission near-infrared (NIR) spectra of solid samples with inconsistent shapes by irradiation with isotropically diffused radiation using polytetrafluoroethylene (PTFE) beads. The Analyst 139:12, pages 3179.
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Solveig Warnecke, Åsmund Rinnan, Morten Allesø & Søren Balling Engelsen. (2013) Measurement of Active Content in Escitalopram Tablets by a Near-Infrared Transmission Spectroscopy Model that Encompasses Batch Variability. Journal of Pharmaceutical Sciences 102:4, pages 1268-1280.
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Jihye Yoon, Jaejin Kim, Pham Khac Duy, Mooeung Kim, Sukwon Kang & Hoeil Chung. (2013) Diffuser-incorporated transmission NIR measurement for reliable analysis of packed granular samples. The Analyst 138:17, pages 4922.
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Andrew O'Neil & Howell Edwards. 2011. Solid State Characterization of Pharmaceuticals. Solid State Characterization of Pharmaceuticals 71 134 .
Stuart L. Cantor, Stephen W. Hoag, Christopher D. Ellison, Mansoor A. Khan & Robbe C. Lyon. (2011) NIR Spectroscopy Applications in the Development of a Compacted Multiparticulate System for Modified Release. AAPS PharmSciTech 12:1, pages 262-278.
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Reuben Domike, Samuel Ngai & Charles L. Cooney. (2010) Light induced fluorescence for predicting API content in tablets: Sampling and error. International Journal of Pharmaceutics 391:1-2, pages 13-20.
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Anthony C. Moffat, Sulaf Assi & Robert A. Watt. (2010) Identifying Counterfeit Medicines Using near Infrared Spectroscopy. Journal of Near Infrared Spectroscopy 18:1, pages 1-15.
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Liwen Liang, Bin Wang, Ye Guo, Hong Ni & Yulin Ren. (2009) A support vector machine-based analysis method with wavelet denoised near-infrared spectroscopy. Vibrational Spectroscopy 49:2, pages 274-277.
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L. Alvarenga, D. Ferreira, D. Altekruse, J.C. Menezes & D. Lochmann. (2008) Tablet identification using near-infrared spectroscopy (NIRS) for pharmaceutical quality control. Journal of Pharmaceutical and Biomedical Analysis 48:1, pages 62-69.
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Masatomo Ito, Tatsuya Suzuki, Shuichi Yada, Akira Kusai, Hiroaki Nakagami, Etsuo Yonemochi & Katsuhide Terada. (2008) Development of a method for the determination of caffeine anhydrate in various designed intact tables by near-infrared spectroscopy: A comparison between reflectance and transmittance technique. Journal of Pharmaceutical and Biomedical Analysis 47:4-5, pages 819-827.
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Steven M. Short, Robert P. Cogdill & Carl A. Anderson. (2008) Figures of Merit Comparison of Reflectance and Transmittance Near-Infrared Methods for the Prediction of Constituent Concentrations in Pharmaceutical Compacts. Journal of Pharmaceutical Innovation 3:1, pages 41-50.
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L. Z. Zhao, Y. Guo, Y. Dou, B. Wang, H. Mi & Y. L. Ren. (2007) Application of artificial neural networks to the nondestructive determination of ciprofloxacin hydrochloride in powder by short-wavelength NIR spectroscopy. Journal of Analytical Chemistry 62:12, pages 1156-1162.
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Jaejin Kim, Jaegeun Noh, Hoeil Chung, Young-Ah Woo, Mark S. Kemper & Youngil Lee. (2007) Direct, non-destructive quantitative measurement of an active pharmaceutical ingredient in an intact capsule formulation using Raman spectroscopy. Analytica Chimica Acta 598:2, pages 280-285.
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Yves Roggo, Pascal Chalus, Lene Maurer, Carmen Lema-Martinez, Aurélie Edmond & Nadine Jent. (2007) A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies. Journal of Pharmaceutical and Biomedical Analysis 44:3, pages 683-700.
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Mark J. Henson & Lin Zhang. (2016) Drug Characterization in Low Dosage Pharmaceutical Tablets Using Raman Microscopic Mapping. Applied Spectroscopy 60:11, pages 1247-1255.
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Tatsuhiko Yamada, Ting-Feng Yeh, Hou-Min Chang, Laigeng Li, John F. Kadla & Vincent L. Chiang. (2006) Rapid analysis of transgenic trees using transmittance near-infrared spectroscopy (NIR). Holzforschung 60:1, pages 24-28.
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Robert Sykes, Bailian Li, Gary Hodge, Barry Goldfarb, John Kadla & H -m Chang. (2005) Prediction of loblolly pine wood properties using transmittance near-infrared spectroscopy. Canadian Journal of Forest Research 35:10, pages 2423-2431.
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Steven J. Doherty & Charles N. Kettler. 2005. Process Analytical Technology. Process Analytical Technology 329 361 .
Y. Roggo, C. Roeseler & M. Ulmschneider. (2004) Near infrared spectroscopy for qualitative comparison of pharmaceutical batches. Journal of Pharmaceutical and Biomedical Analysis 36:4, pages 777-786.
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Ralph Carsten Schneider & Karl-Artur Kovar. (2003) Analysis of ecstasy tablets: comparison of reflectance and transmittance near infrared spectroscopy. Forensic Science International 134:2-3, pages 187-195.
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Mark S. Kemper & Leza M. Luchetta. (2017) A Guide to Raw Material Analysis Using near Infrared Spectroscopy. Journal of Near Infrared Spectroscopy 11:3, pages 155-174.
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