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Pharmaceutical Development and Technology Volume 6, 2001 - Issue 1
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Research Article

A Comparison of Reflectance and Transmittance Near-Infrared Spectroscopic Techniques in Determining Drug Content in Intact Tablets

Shilpa S. Thosar Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, Memphis, TN, U.S.A.
,
Reba A. Forbess Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, Memphis, TN, U.S.A.
,
Nkere K. Ebube Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, Memphis, TN, U.S.A.
,
Yixin Chen Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, Memphis, TN, U.S.A.
,
Ronald L. Rubinovitz Foss NIR Systems, Inc., Silver Spring, MD, U.S.A.
,
Mark S. Kemper Foss NIR Systems, Inc., Silver Spring, MD, U.S.A.
,
George E. Reier
,
Thomas A. Wheatley
&
Atul J. Shukla Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, Memphis, TN, U.S.A.; Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, 26 South Dunlap, 214 Feurt Building, Memphis, TN, 38163, U.S.A.
 show all
Pages 19-29 | Received 31 Jul 1998, Accepted 09 Apr 2000, Published online: 25 Jan 2001

REFERENCES

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  • Gottfries J., Depui H., Fransson M., Jongeneelen M., Josefson M., Langkilde F., Witte D. Vibrational Spectrometry for the Assessment of Active Substance in Metoprolol Tablets: A Comparison Between Transmission and Diffuse Reflectance Near-Infrared Spectroscopy. J. Pharm. Biomed. Anal. 1996; 14: 1495–1503
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