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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 12, 2009 - Issue 2
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Research articles

Cognitive and mood effects of 8 weeks' supplementation with 400 mg or 1000 mg of the omega-3 essential fatty acid docosahexaenoic acid (DHA) in healthy children aged 10–12 years

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Pages 48-56 | Published online: 19 Jul 2013

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Hugo A. E. Morandini, Pradeep Rao, Sean D. Hood, Kristi Griffiths, Timothy J. Silk & Florian D. Zepf. (2022) Effects of dietary omega-3 intake on vigilant attention and resting-state functional connectivity in neurotypical children and adolescents. Nutritional Neuroscience 25:11, pages 2269-2278.
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Magdalena Ogłuszka, Paweł Lipiński & Rafał Radosław Starzyński. (2022) Interaction between iron and omega-3 fatty acids metabolisms: where is the cross-link?. Critical Reviews in Food Science and Nutrition 62:11, pages 3002-3022.
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Jens Bo Nielsen, Maria Willerslev-Olsen, Lasse Christiansen, Jesper Lundbye-Jensen & Jakob Lorentzen. (2015) Science-Based Neurorehabilitation: Recommendations for Neurorehabilitation From Basic Science. Journal of Motor Behavior 47:1, pages 7-17.
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Justin E. Karr, Joel E. Alexander & Robert G. Winningham. (2011) Omega-3 polyunsaturated fatty acids and cognition throughout the lifespan: A review. Nutritional Neuroscience 14:5, pages 216-225.
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Gillian England-Mason & Deborah Dewey. 2023. Handbook of Clinical Child Psychology. Handbook of Clinical Child Psychology 235 268 .
Dean SherzaiRoman MonessSophia SherzaiAyesha Sherzai. (2022) A Systematic Review of Omega-3 Fatty Acid Consumption and Cognitive Outcomes in Neurodevelopment. American Journal of Lifestyle Medicine, pages 155982762211160.
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Xin Wang, Xiaojing Song, Yuying Jin, Xiaoling Zhan, Muqing Cao, Xuning Guo, Siyu Liu, Xiaoxuan Ou, Tingfeng Gu, Jin Jing, Li Cai & Xiuhong Li. (2022) Association between dietary quality and executive functions in school-aged children with autism spectrum disorder. Frontiers in Nutrition 9.
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Melissa Basso, Nicola Johnstone, Paul Knytl, Arjen Nauta, Andre Groeneveld & Kathrin Cohen Kadosh. (2022) A Systematic Review of Psychobiotic Interventions in Children and Adolescents to Enhance Cognitive Functioning and Emotional Behavior. Nutrients 14:3, pages 614.
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Subash Raj Susai, Sophie Sabherwal, David Mongan, Melanie Föcking & David R. Cotter. (2021) Omega‐3 fatty acid in ultra‐high‐risk psychosis: A systematic review based on functional outcome. Early Intervention in Psychiatry 16:1, pages 3-16.
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Sarah E Costello, Eveline Geiser & Nora Schneider. (2021) Nutrients for executive function development and related brain connectivity in school-aged children. Nutrition Reviews 79:12, pages 1293-1306.
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Devaraj Parasannanavar, Indraja Gaddam, Tulja Bukya, Ahamed Ibrahim S, Suryam Reddy K, Santosh Kumar Banjara, Blessy P Priyanka Salvadi, Naveen Kumar B, Sylvia Fernandez Rao, J J Babu Geddam & Hemalatha Rajkumar. (2021) Omega-3 polyunsaturated fatty acid intake and plasma fatty acids of school going Indian children - a cross-sectional study. Prostaglandins, Leukotrienes and Essential Fatty Acids 170, pages 102294.
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Guo-Yi Yang, Ting Wu, Si-Yu Huang, Bi-Xia Huang, Hai-Lin Wang, Qiu-Ye Lan, Chun-Lei Li, Hui-Lian Zhu & Ai-Ping Fang. (2020) No effect of 6-month supplementation with 300 mg/d docosahexaenoic acid on executive functions among healthy school-aged children: a randomized, double-blind, placebo-controlled trial. European Journal of Nutrition 60:4, pages 1985-1997.
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Stine Vuholm, Marie N. Teisen, Christian Mølgaard, Lotte Lauritzen & Camilla T. Damsgaard. (2021) Sleep and physical activity in healthy 8–9-year-old children are affected by oily fish consumption in the FiSK Junior randomized trial. European Journal of Nutrition.
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Inge S.M. van der Wurff, Barbara J. Meyer & Renate H.M. de Groot. (2020) Effect of Omega-3 Long Chain Polyunsaturated Fatty Acids (n-3 LCPUFA) Supplementation on Cognition in Children and Adolescents: A Systematic Literature Review with a Focus on n-3 LCPUFA Blood Values and Dose of DHA and EPA. Nutrients 12:10, pages 3115.
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Marie N Teisen, Stine Vuholm, Janni Niclasen, Juan J Aristizabal-Henao, Ken D Stark, Svend S Geertsen, Camilla T Damsgaard & Lotte Lauritzen. (2020) Effects of oily fish intake on cognitive and socioemotional function in healthy 8–9-year-old children: the FiSK Junior randomized trial. The American Journal of Clinical Nutrition 112:1, pages 74-83.
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Sophie Emery, Isabelle Häberling, Gregor Berger, Susanne Walitza, Klaus Schmeck, Therese Albert, Noemi Baumgartner, Michael Strumberger, Mona Albermann & Renate Drechsler. (2020) Omega-3 and its domain-specific effects on cognitive test performance in youths: A meta-analysis. Neuroscience & Biobehavioral Reviews 112, pages 420-436.
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Amy Heard Egbert, Chloe Creber, Dorothy M. Loren & Amy M. Bohnert. (2019) Executive function and dietary intake in youth: A systematic review of the literature. Appetite 139, pages 197-212.
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Inge S.M. van der Wurff, Clemens von Schacky, Trygve Bergeland, Roeslan Leontjevas, Maurice P. Zeegers, Jelle Jolles, Paul A. Kirschner & Renate H.M. de Groot. (2019) Effect of 1 Year Krill Oil Supplementation on Cognitive Achievement of Dutch Adolescents: A Double-Blind Randomized Controlled Trial. Nutrients 11:6, pages 1230.
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Marie N. Teisen, Janni Niclasen, Stine Vuholm, Jesper Lundbye-Jensen, Ken D. Stark, Camilla T. Damsgaard, Svend S. Geertsen & Lotte Lauritzen. (2019) Exploring correlations between neuropsychological measures and domain-specific consistency in associations with n-3 LCPUFA status in 8-9 year-old boys and girls. PLOS ONE 14:5, pages e0216696.
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Grace E. Giles, Caroline R. Mahoney & Robin B. Kanarek. 2019. Omega Fatty Acids in Brain and Neurological Health. Omega Fatty Acids in Brain and Neurological Health 313 355 .
Hans Demmelmair, Anita MacDonald, Urania Kotzaeridou, Peter Burgard, Domingo Gonzalez-Lamuno, Elvira Verduci, Melike Ersoy, Gulden Gokcay, Behiye Alyanak, Eva Reischl, Wolfgang Müller-Felber, Fabienne Faber, Uschi Handel, Sabrina Paci & Berthold Koletzko. (2018) Determinants of Plasma Docosahexaenoic Acid Levels and Their Relationship to Neurological and Cognitive Functions in PKU Patients: A Double Blind Randomized Supplementation Study. Nutrients 10:12, pages 1944.
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Katina Handeland, Siv Skotheim, Valborg Baste, Ingvild E. Graff, Livar Frøyland, Øyvind Lie, Marian Kjellevold, Maria W. Markhus, Kjell M. Stormark, Jannike Øyen & Lisbeth Dahl. (2018) The effects of fatty fish intake on adolescents’ nutritional status and associations with attention performance: results from the FINS-TEENS randomized controlled trial. Nutrition Journal 17:1.
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Sarah A Keim, Barbara Gracious, Kelly M Boone, Mark A Klebanoff, Lynette K Rogers, Joseph Rausch, Daniel L Coury, Kelly W Sheppard, Jesse Husk & Dale A Rhoda. (2018) ω-3 and ω-6 Fatty Acid Supplementation May Reduce Autism Symptoms Based on Parent Report in Preterm Toddlers. The Journal of Nutrition 148:2, pages 227-235.
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Solvejg L. Hansen, Anina Ritterband-Rosenbaum, Camilla B. Voigt, Lars I. Hellgren, Ann-Dorit M. Sørensen, Charlotte Jacobsen, Line Z. Greve, Katrine D. Jørgensen, Peder E. Bilde, Bente Kiens & Jens B. Nielsen. (2017) Supplementation of docosahexaenoic acid (DHA), vitamin D3 and uridine in combination with six weeks of cognitive and motor training in prepubescent children: a pilot study. BMC Nutrition 3:1.
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Inge van der Wurff, Barbara Meyer & Renate de Groot. (2017) A Review of Recruitment, Adherence and Drop-Out Rates in Omega-3 Polyunsaturated Fatty Acid Supplementation Trials in Children and Adolescents. Nutrients 9:5, pages 474.
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Mats Johnson, Gunnar Fransson, Sven Östlund, Björn Areskoug & Christopher Gillberg. (2017) Omega 3/6 fatty acids for reading in children: a randomized, double-blind, placebo-controlled trial in 9-year-old mainstream schoolchildren in Sweden. Journal of Child Psychology and Psychiatry 58:1, pages 83-93.
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Camilla T. Damsgaard, Lotte Lauritzen, Hanne Hauger, Stine Vuholm, Marie N. Teisen, Christian Ritz, Max Hansen, Janni Niclasen & Christian Mølgaard. (2016) Effects of oily fish intake on cardiovascular risk markers, cognitive function, and behavior in school-aged children: study protocol for a randomized controlled trial. Trials 17:1.
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Matteo M. Pusceddu, Philip Kelly, Catherine Stanton, John F. Cryan & Timothy G. Dinan. (2016) N-3 Polyunsaturated Fatty Acids through the Lifespan: Implication for Psychopathology. International Journal of Neuropsychopharmacology 19:12, pages pyw078.
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Lotte Lauritzen, Paolo Brambilla, Alessandra Mazzocchi, Laurine Harsløf, Valentina Ciappolino & Carlo Agostoni. (2016) DHA Effects in Brain Development and Function. Nutrients 8:1, pages 6.
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Inge van der Wurff, Clemens von Schacky, Kjetil Berge, Maurice Zeegers, Paul Kirschner & Renate de Groot. (2016) Association between Blood Omega-3 Index and Cognition in Typically Developing Dutch Adolescents. Nutrients 8:1, pages 13.
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Ruth E Cooper, Charlotte Tye, Jonna Kuntsi, Evangelos Vassos & Philip Asherson. (2016) The effect of omega-3 polyunsaturated fatty acid supplementation on emotional dysregulation, oppositional behaviour and conduct problems in ADHD: A systematic review and meta-analysis. Journal of Affective Disorders 190, pages 474-482.
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Jeannine Baumgartner. 2016. Handbook of Lipids in Human Function. Handbook of Lipids in Human Function 331 375 .
Louise Bergmann Sørensen, Camilla Trab Damsgaard, Stine-Mathilde Dalskov, Rikke Agnete Petersen, Niels Egelund, Camilla Brørup Dyssegaard, Ken D. Stark, Rikke Andersen, Inge Tetens, Arne Astrup, Kim Fleisher Michaelsen & Lotte Lauritzen. (2015) Diet-induced changes in iron and n -3 fatty acid status and associations with cognitive performance in 8–11-year-old Danish children: secondary analyses of the Optimal Well-Being, Development and Health for Danish Children through a Healthy New Nordic Diet School Meal Study . British Journal of Nutrition 114:10, pages 1623-1637.
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Ruth E Cooper, Charlotte Tye, Jonna Kuntsi, Evangelos Vassos & Philip Asherson. (2015) Omega-3 polyunsaturated fatty acid supplementation and cognition: A systematic review and meta-analysis. Journal of Psychopharmacology 29:7, pages 753-763.
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Katina D. Handeland, Maria Wik Markhus, Eli Aadland, Lisbeth Dahl, Lisa Midtbø, Ingvild E. Graff, Livar Frøyland, Marian Kjellevold Malde & Jannike Øyen. (2015) KJAPP I TOPPEN MED FISK I KROPPEN!. Norsk tidsskrift for ernæring 13:2, pages 6-11.
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Cornelius M. Smuts, Jani Greeff, Jane Kvalsvig, Michael B. Zimmermann & Jeannine Baumgartner. (2014) Long-chain n -3 PUFA supplementation decreases physical activity during class time in iron-deficient South African school children . British Journal of Nutrition 113:2, pages 212-224.
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Welma Stonehouse. (2014) Does Consumption of LC Omega-3 PUFA Enhance Cognitive Performance in Healthy School-Aged Children and throughout Adulthood? Evidence from Clinical Trials. Nutrients 6:7, pages 2730-2758.
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C. Joffre, A. Nadjar, M. Lebbadi, F. Calon & S. Laye. (2014) n-3 LCPUFA improves cognition: The young, the old and the sick. Prostaglandins, Leukotrienes and Essential Fatty Acids 91:1-2, pages 1-20.
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Ver?nica Portillo-Reyes, Miguel P?rez-Garc?a, Yolanda Loya-M?ndez & Antonio E. Puente. (2014) Clinical significance of neuropsychological improvement after supplementation with omega-3 in 8?12 years old malnourished Mexican children: A randomized, double-blind, placebo and treatment clinical trial. Research in Developmental Disabilities 35:4, pages 861-870.
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Jason Mazanov, Matthew Dunn, James Connor & Mai-Lee Fielding. (2013) Substance use to enhance academic performance among Australian university students. Performance Enhancement & Health 2:3, pages 110-118.
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Natalie Parletta, Patrick Cooper, Debra N. Gent, John Petkov & Kerin O'Dea. (2013) Effects of fish oil supplementation on learning and behaviour of children from Australian Indigenous remote community schools: A randomised controlled trial. Prostaglandins, Leukotrienes and Essential Fatty Acids 89:2-3, pages 71-79.
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D. Benton, R. T. Donohoe, D. E. Clayton & S. J. Long. (2012) Supplementation with DHA and the psychological functioning of young adults. British Journal of Nutrition 109:1, pages 155-161.
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