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Original Article

An evaluation of patient preference for an alternative insulin delivery system compared to standard vial and syringe

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Pages 133-146 | Accepted 30 Oct 2006, Published online: 14 Dec 2006

Keep up to date with the latest research on this topic with citation updates for this article.

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M. Valentini, M. Scardapane, F. Bondanini, A. Bossi, A. Colatrella, A. Girelli, A. Ciucci, S. Leotta, E. Minotti, F. Pasotti, A. Pesenti, L. Rocca, L. Sciangula, E. Vavassori & A. Nicolucci. (2015) Efficacy, safety and acceptability of the new pen needle 33G × 4 mm. AGO 01 study. Current Medical Research and Opinion 31:3, pages 487-492.
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Michael Grabner, James Chu, Swetha Raparla, Ralph Quimbo, Steve Zhou & Joseph Conoshenti. (2013) Clinical and Economic Outcomes Among Patients With Diabetes Mellitus Initiating Insulin Glargine Pen Versus Vial. Postgraduate Medicine 125:3, pages 204-213.
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David Oyer, Marcus Niemeyer & Alan Moses. (2012) Empowering People with Diabetes: Improving Perceptions and Outcomes with Technical Advances in Insulin Pens. Postgraduate Medicine 124:5, pages 110-120.
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Carlos Campos, Rosemarie Lajara & Tony Deluzio. (2012) Usability and preference assessment of a new prefilled insulin pen versus vial and syringe in people with diabetes, physicians and nurses. Expert Opinion on Pharmacotherapy 13:13, pages 1837-1846.
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Christina Schipper, Petra Musholt, Marcus Niemeyer, Marianne Qvist, Andrea Löffler, Thomas Forst & Andreas Pfützner. (2012) Patient device assessment evaluation of two insulin injection devices in a mixed cohort of insulin-treated patients with type 1 or type 2 diabetes mellitus. Current Medical Research and Opinion 28:8, pages 1297-1303.
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Daniel A. Nadeau, Carlos Campos, Marcus Niemeyer & Timothy Bailey. (2012) Healthcare professional and patient assessment of a new prefilled insulin pen versus two widely available prefilled insulin pens for ease of use, teaching and learning. Current Medical Research and Opinion 28:1, pages 3-13.
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Kate Van Brunt, Louis S Matza, Peter M Classi & Joseph A Johnston. (2011) Preferences related to attention-deficit/hyperactivity disorder and its treatment. Patient Preference and Adherence 5, pages 33-43.
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Sherwyn L Schwartz, Debra A Ignaut & Jennifer N Bodie. (2010) Humalog® KwikPen™: an insulin-injecting pen designed for ease of use. Expert Review of Medical Devices 7:6, pages 735-743.
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Laurence J. Hirsch, Michael A. Gibney, John Albanese, Shankang Qu, Kenneth Kassler-Taub, Leslie J. Klaff & Timothy S. Bailey. (2010) Comparative glycemic control, safety and patient ratings for a new 4 mm × 32G insulin pen needle in adults with diabetes. Current Medical Research and Opinion 26:6, pages 1531-1541.
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T Asakura, H Seino, M Kageyama & N Yohkoh. (2009) Evaluation of injection force of three insulin delivery pens. Expert Opinion on Pharmacotherapy 10:9, pages 1389-1393.
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Alex Z. Fu, Ying Qiu & Larry Radican. (2009) Impact of fear of insulin or fear of injection on treatment outcomes of patients with diabetes. Current Medical Research and Opinion 25:6, pages 1413-1420.
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Andreas Pfützner. (2009) FlexPen® for the delivery of insulin: accuracy, injection force and patient preference. Expert Review of Medical Devices 6:2, pages 115-123.
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A. Pfützner, T. Reimer, C. Hohberg, L. P. F. Frøkjær & C. Jørgensen. (2008) Prefilled insulin device with reduced injection force: patient perception and accuracy. Current Medical Research and Opinion 24:9, pages 2545-2549.
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A Pfützner, T Asakura, B Sommavilla & WC Lee. (2008) Insulin delivery with FlexPen®: dose accuracy, patient preference and adherence. Expert Opinion on Drug Delivery 5:8, pages 915-925.
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Mark Peyrot & Richard R. Rubin. (2008) Physician perception and recommendation of insulin pens for patients with type 2 diabetes mellitus. Current Medical Research and Opinion 24:8, pages 2413-2422.
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Debra A Ignaut & Willem JRR Venekamp. (2007) HumaPen® Memoir™: a novel insulin-injecting pen with a dose-memory feature. Expert Review of Medical Devices 4:6, pages 793-802.
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Colin H. Ridyard, Dalia M. M. Dawoud, Lorna V. Tuersley & Dyfrig A. Hughes. (2016) A Systematic Review of Patients’ Perspectives on the Subcutaneous Route of Medication Administration. The Patient - Patient-Centered Outcomes Research 9:4, pages 281-292.
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Danny D Meetoo. (2016) Insulin: An evolving paradigm in diabetes management. Practice Nursing 27:Sup3, pages 11-16.
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Susan LaRue & Jaret Malloy. (2015) Evaluation of the Dual-Chamber Pen Design for the Injection of Exenatide Once Weekly for the Treatment of Type 2 Diabetes. Journal of Diabetes Science and Technology 9:4, pages 815-821.
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Andrew AhmannSheryl L. SzeinbachJasvinder GillLouise TraylorSatish K. Garg. (2014) Comparing Patient Preferences and Healthcare Provider Recommendations with the Pen Versus Vial-and-Syringe Insulin Delivery in Patients with Type 2 Diabetes. Diabetes Technology & Therapeutics 16:2, pages 76-83.
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Robert M. Cuddihy & Sarah K. Borgman. (2013) Considerations for Diabetes. American Journal of Therapeutics 20:6, pages 694-702.
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Susan M. Joy, Emily Little, Nisa M. Maruthur, Tanjala S. Purnell & John F. P. Bridges. (2013) Patient Preferences for the Treatment of Type 2 Diabetes: A Scoping Review. PharmacoEconomics 31:10, pages 877-892.
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Takashi MiwaRokuro ItohTakaaki KobayashiTakashi TanabeJunpei ShikumaTomono TakahashiMasato Odawara. (2012) Comparison of the Effects of a New 32-Gauge×4-mm Pen Needle and a 32-Gauge×6-mm Pen Needle on Glycemic Control, Safety, and Patient Ratings in Japanese Adults with Diabetes. Diabetes Technology & Therapeutics 14:12, pages 1084-1090.
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Kellie J. Antinori-Lent. (2012) Analysis of Comparison of Patient Preference for Two Insulin Injection Pen Devices in Relation to Patient Dexterity Skills. Journal of Diabetes Science and Technology 6:4, pages 917-920.
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Danny MeetooGillian McAllister, Adele West & Mandy Turnbull. (2012) In pursuit of excellence in diabetes care: trends in insulin delivery. British Journal of Nursing 21:10, pages 588-595.
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Burkhard Ludescher, Marc Rommel, Tobias Willmer, Andreas Fritsche, Fritz Schick & Juergen Machann. (2011) Subcutaneous adipose tissue thickness in adults - correlation with BMI and recommendations for pen needle lengths for subcutaneous self-injection. Clinical Endocrinology 75:6, pages 786-790.
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Barbara J. AndersonMaria J. Redondo. (2011) What Can We Learn from Patient-Reported Outcomes of Insulin Pen Devices?. Journal of Diabetes Science and Technology 5:6, pages 1563-1571.
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Ragnar Hanas, Carine de Beaufort, Hilary Hoey & Barbara Anderson. (2011) Insulin delivery by injection in children and adolescents with diabetes. Pediatric Diabetes 12:5, pages 518-526.
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Jayne Hodgkiss. (2010) Incretin-based therapies for type 2 diabetes: a nurse’s perspective. British Journal of Nursing 19:21, pages 1337-1344.
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Birthe S. Olsen, Søren Kruse Lilleøre, Conny Nøhr Korsholm & Thorben Kracht. (2010) Novopen Echo® for the Delivery of Insulin: A Comparison of Usability, Functionality and Preference among Pediatric Subjects, Their Parents, and Health Care Professionals. Journal of Diabetes Science and Technology 4:6, pages 1468-1475.
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Susan Cornell. (2010) Managing diabetes-related costs and quality of life issues: Value of insulin analogs and pens for inpatient use. Health Policy 96:3, pages 191-199.
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A. N. Naegeli & R. P. Hayes. (2010) Expectations about and experiences with insulin therapy contribute to diabetes treatment satisfaction in insulin-naïve patients with type 2 diabetes. International Journal of Clinical Practice 64:7, pages 908-916.
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Kiyomi MasudaKazutaka AokiKaori KikuchiUru NezuTomonori MuraokaKazuaki ShinodaAkinobu NakamuraMakoto ShibuyaMayumi TakahashiMari KimuraYasuo Terauchi. (2010) Self-Injection of Insulin Using Appropriate Supportive Devices in Handicapped Subjects with Diabetes. Diabetes Technology & Therapeutics 12:6, pages 483-490.
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Lisa Kroon. (2009) An Analysis of Patient Acceptance and Safety of a Prefilled Insulin Injection Device. Journal of Diabetes Science and Technology 3:6, pages 1439-1441.
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Lisa Kroon. (2009) Overview of insulin delivery pen devices. Journal of the American Pharmacists Association 49:5, pages e118-e131.
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Debra A. Ignaut, Sherwyn L. Schwartz, Samiha Sarwat & Heather L. Murphy. (2009) Comparative Device Assessments. The Diabetes Educator 35:5, pages 789-798.
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Cliff MolifeLauren J. LeeLizheng ShiMonika SawhneySheila M. Lenox. (2009) Assessment of Patient-Reported Outcomes of Insulin Pen Devices Versus Conventional Vial and Syringe. Diabetes Technology & Therapeutics 11:8, pages 529-538.
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Risa P. HayesJames T. Fitzgerald. (2009) Perceptions and Attitudes Are Primary Contributors to Insulin Delivery System Satisfaction in People with Type 2 Diabetes. Diabetes Technology & Therapeutics 11:7, pages 419-426.
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Amna A. ShaghouliBaiju R. Shah. (2009) The Prescription of Insulin Pen Devices Versus Syringes for Older People with Diabetes. Diabetes Technology & Therapeutics 11:7, pages 439-442.
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Charles F. ShaeferJr.Jr.. (2009) The pen is mightier than the sword. Insulin 4:3, pages 132-135.
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C. Bradley & C. J. B. Gilbride. (2008) Improving treatment satisfaction and other patient-reported outcomes in people with type 2 diabetes: the role of once-daily insulin glargine. Diabetes, Obesity and Metabolism 10:s2, pages 50-65.
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. (2008) Current World Literature. Current Opinion in Endocrinology, Diabetes & Obesity 15:2, pages 193-219.
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Ernest Asamoah. (2008) Insulin Pen—The “iPod” for Insulin Delivery (Why Pen Wins over Syringe). Journal of Diabetes Science and Technology 2:2, pages 292-296.
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Martha M. Funnell. (2008) Quality of Life and Insulin Therapy in Type 2 Diabetes Mellitus. Insulin 3:1, pages 31-36.
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Michael A. Magnolti & Elliot J. Rayfield. (2007) An Update on Insulin Injection Devices. Insulin 2:4, pages 173-181.
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David Cobden, Won Chan Lee, Sanjeev Balu, Ashish V Joshi & Chris L Pashos. (2007) Health Outcomes and Economic Impact of Therapy Conversion to a Biphasic Insulin Analog Pen Among Privately Insured Patients with Type 2 Diabetes Mellitus. Pharmacotherapy 27:7, pages 948-962.
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