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Original Article

A randomized, double-blind, phase III study comparing multiple doses of tapentadol IR, oxycodone IR, and placebo for postoperative (bunionectomy) pain

, , , &
Pages 765-776 | Accepted 07 Jan 2009, Published online: 09 Feb 2009

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Read on this site (29)

Estelle Watson, Akash Khandelwal, Jan Freijer, John van den Anker, Claudia Lefeber & Mariëlle Eerdekens. (2019) Population pharmacokinetic modeling to facilitate dose selection of tapentadol in the pediatric population. Journal of Pain Research 12, pages 2835-2850.
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R. Ffrench-O’Carroll, H. Steinhaeuser, S. Duff, J. Close, J. McNamara, N. Ahmed, M. Murray, T. Rice & S. Immanni. (2019) A randomized controlled trial comparing tapentadol with oxycodone in non-breastfeeding women post elective cesarean section. Current Medical Research and Opinion 35:6, pages 975-981.
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Laura E. Gressler, Drayton A. Hammond & Jacob T. Painter. (2017) Serotonin Syndrome in Tapentadol Literature: Systematic Review of Original Research. Journal of Pain & Palliative Care Pharmacotherapy 31:3-4, pages 228-236.
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Yeung-Jen Chen, Chao-Ching Chiang, Peng-Ju Huang, Jason Huang, Keith Karcher & Honglan Li. (2015) Tapentadol immediate-release for acute postbunionectomy pain: a phase 3, randomized, double-blind, placebo-controlled, parallel-group study in Taiwan. Current Medical Research and Opinion 31:11, pages 2001-2009.
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Nebojsa Nick Knezevic, Tatiana Tverdohleb, Ivana Knezevic & Kenneth D Candido. (2015) Unique pharmacology of tapentadol for treating acute and chronic pain. Expert Opinion on Drug Metabolism & Toxicology 11:9, pages 1475-1492.
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Ashley JB MacLean & Thomas L Schwartz. (2015) Tramadol for the treatment of fibromyalgia. Expert Review of Neurotherapeutics 15:5, pages 469-475.
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Neil Singla, Rachel Margulis, Kenneth Kostenbader, Yanping Zheng, Thomas Barrett, Michael J. Giuliani, Yin Chen & Jim L. Young. (2015) Randomized, double-blind, placebo-controlled study of the efficacy and safety of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen tablets for acute postoperative pain. The Physician and Sportsmedicine 43:2, pages 126-137.
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Neil Singla, Thomas Barrett, Lisa Sisk, Kenneth Kostenbader & Jim Young. (2014) Assessment of the safety and efficacy of extended-release oxycodone/acetaminophen, for 14 days postsurgery. Current Medical Research and Opinion 30:12, pages 2571-2578.
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Y. K. Lee, J. S. Ko, H. Y. Rhim, E. J. Lee, K. Karcher, H. Li, D. Shapiro & H. S. Lee. (2014) Acute postoperative pain relief with immediate-release tapentadol: randomized, double-blind, placebo-controlled study conducted in South Korea. Current Medical Research and Opinion 30:12, pages 2561-2570.
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Nalini Vadivelu, Yili Huang, Brian Mirante, Michael Jacoby, Ferne R Braveman, Roberta L Hines & Raymond Sinatra. (2013) Patient considerations in the use of tapentadol for moderate to severe pain. Drug, Healthcare and Patient Safety 5, pages 151-159.
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Robert B Raffa, Helmut Buschmann, Thomas Christoph, Gary Eichenbaum, Werner Englberger, Christopher M Flores, Torsten Hertrampf, Babette Kögel, Klaus Schiene, Wolfgang Straßburger, Rolf Terlinden & Thomas M Tzschentke. (2012) Mechanistic and functional differentiation of tapentadol and tramadol. Expert Opinion on Pharmacotherapy 13:10, pages 1437-1449.
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Robert B Raffa, Ronald J Tallarida, Robert Taylor$suffix/text()$suffix/text() & Joseph V Pergolizzi$suffix/text()$suffix/text(). (2012) Fixed-dose combinations for emerging treatment of pain. Expert Opinion on Pharmacotherapy 13:9, pages 1261-1270.
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Craig T Hartrick & Jose Rafael Rodríguez Hernandez. (2012) Tapentadol for pain: a treatment evaluation. Expert Opinion on Pharmacotherapy 13:2, pages 283-286.
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Nalini Vadivelu, Alexander Timchenko, Yili Huang & Raymond Sinatra. (2011) Tapentadol extended-release for treatment of chronic pain: a review. Journal of Pain Research 4, pages 211-218.
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Stephen E. Daniels, Ron J. Spivey, Sonia Singla, Michael Golf & Francis J. Clark. (2011) Efficacy and safety of oxycodone HCl/niacin tablets for the treatment of moderate-to-severe postoperative pain following bunionectomy surgery. Current Medical Research and Opinion 27:3, pages 593-603.
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Marc Afilalo, Jens-Ulrich Stegmann & David Upmalis. (2010) Tapentadol immediate release: a new treatment option for acute pain management. Journal of Pain Research 3, pages 1-9.
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Robert Buynak, Douglas Y Shapiro, Akiko Okamoto, Ilse Van Hove, Christine Rauschkolb, Achim Steup, Bernd Lange, Claudia Lange & Mila Etropolski. (2010) Efficacy and safety of tapentadol extended release for the management of chronic low back pain: results of a prospective, randomized, double-blind, placebo- and active-controlled Phase III study. Expert Opinion on Pharmacotherapy 11:11, pages 1787-1804.
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Paul Sloan. (2010) Tapentadol for acute and chronic pain. Expert Opinion on Pharmacotherapy 11:11, pages 1783-1785.
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Craig T Hartrick. (2010) Tapentadol immediate-release for acute pain. Expert Review of Neurotherapeutics 10:6, pages 861-869.
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Craig T Hartrick. (2009) Tapentadol immediate release for the relief of moderate-to-severe acute pain. Expert Opinion on Pharmacotherapy 10:16, pages 2687-2696.
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Stephen Daniels, Ed Casson, Jens-Ulrich Stegmann, Charles Oh, Akiko Okamoto, Christine Rauschkolb & David Upmalis. (2009) A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute pain. Current Medical Research and Opinion 25:6, pages 1551-1561.
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Martin Hale, David Upmalis, Akiko Okamoto, Claudia Lange & Christine Rauschkolb. (2009) Tolerability of tapentadol immediate release in patients with lower back pain or osteoarthritis of the hip or knee over 90 days: a randomized, double-blind study. Current Medical Research and Opinion 25:5, pages 1095-1104.
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