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Original Article

Effect of saxagliptin monotherapy in treatment-naïve patients with type 2 diabetes

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Pages 2401-2411 | Accepted 13 Jul 2009, Published online: 04 Aug 2009

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Read on this site (47)

Woh Yon Mak,Jivanraj R. Nagarajah,Hannah Abdul Halim,Anitha Ramadas,Zulsairi Mohd Pauzi,Lay Ting Pee & Nirmala Jagan. (2020) Dipeptidyl Peptidase-4 inhibitors use in type II diabetic patients in a tertiary hospital. Journal of Pharmaceutical Policy and Practice 13:1.
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Kazuki Orime & Yasuo Terauchi. (2020) Efficacy and safety of saxagliptin for the treatment of type 2 diabetes mellitus. Expert Opinion on Pharmacotherapy 21:17, pages 2101-2114.
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Kathryn M. Hurren & Marissa W. Dunham. (2018) Understanding the impact of commonly utilized, non-insulin, glucose-lowering drugs on body weight in patients with type 2 diabetes. Expert Opinion on Pharmacotherapy 19:10, pages 1087-1095.
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Takashi Kadowaki, Satsuki Muto, Yoshiumi Ouchi, Ryutaro Shimazaki & Yutaka Seino. (2017) Efficacy and safety of saxagliptin in combination with insulin in Japanese patients with type 2 diabetes mellitus: a 16-week double-blind randomized controlled trial with a 36-week open-label extension. Expert Opinion on Pharmacotherapy 18:18, pages 1903-1919.
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Huan Yu & Vincent C Woo. (2017) Emerging use of combination therapies for the management of type 2 diabetes – focus on saxagliptin and dapagliflozin. Diabetes, Metabolic Syndrome and Obesity 10, pages 317-332.
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Lisa M. Younk, Elizabeth M. Lamos & Stephen N. Davis. (2016) Cardiovascular effects of anti-diabetes drugs. Expert Opinion on Drug Safety 15:9, pages 1239-1257.
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Rose Anderson, Jennifer Hayes & Jeffrey W. Stephens. (2016) Pharmacokinetic, pharmacodynamic and clinical evaluation of saxagliptin in type 2 diabetes. Expert Opinion on Drug Metabolism & Toxicology 12:4, pages 467-473.
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Marc Evans, Stephen C. Bain & Jiten Vora. (2016) A systematic review of the safety of incretin-based therapies in type 2 diabetes. Expert Review of Endocrinology & Metabolism 11:2, pages 217-232.
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Tamer Yacoub. (2016) Dapagliflozin combination therapy in type 2 diabetes mellitus. Postgraduate Medicine 128:1, pages 124-136.
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Charles Andy Schuetz, Siew Hwa Ong & Matthias Blüher. (2015) Clinical trial simulation methods for estimating the impact of DPP-4 inhibitors on cardiovascular disease. ClinicoEconomics and Outcomes Research 7, pages 313-323.
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Shinya Nishio, Mariko Abe & Hiroyuki Ito. (2015) Anagliptin in the treatment of type 2 diabetes: safety, efficacy, and patient acceptability. Diabetes, Metabolic Syndrome and Obesity 8, pages 163-171.
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Wayne H.-H. Sheu, Sung Woo Park, Yan Gong, Sabine Pinnetti, Sudipta Bhattacharya, Sanjay Patel, Thomas Seck & Hans-Juergen Woerle. (2015) Linagliptin improves glycemic control after 1 year as add-on therapy to basal insulin in Asian patients with type 2 diabetes mellitus. Current Medical Research and Opinion 31:3, pages 503-512.
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Hiroyuki Konya, Yuzo Yano, Satoshi Matsutani, Taku Tsunoda, Takashi Ikawa, Yoshiki Kusunoki, Toshihiro Matsuo, Masayuki Miuchi, Tomoyuki Katsuno, Tomoya Hamaguchi, Jun-ichiro Miyagawa & Mitsuyoshi Namba. (2014) Profile of saxagliptin in the treatment of type 2 diabetes: focus on Japanese patients. Therapeutics and Clinical Risk Management 10, pages 547-558.
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Stanley Schwartz. (2014) Evidence-Based Practice Use of Incretin-Based Therapy in the Natural History of Diabetes. Postgraduate Medicine 126:3, pages 66-84.
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Matthew L. Mintz & Gianmaria Minervini. (2014) Saxagliptin versus glipizide as add-on therapy to metformin: assessment of hypoglycemia. Current Medical Research and Opinion 30:5, pages 761-770.
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John Gerich. (2013) Pathogenesis and management of postprandial hyperglycemia: role of incretin-based therapies. International Journal of General Medicine 6, pages 877-895.
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Stephanie Aleskow Stein, Elizabeth Mary Lamos & Stephen N Davis. (2013) A review of the efficacy and safety of oral antidiabetic drugs. Expert Opinion on Drug Safety 12:2, pages 153-175.
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Chetan S Karyekar, Shoba Ravichandran, Elsie Allen, Douglas Fleming & Robert Frederich. (2013) Tolerability and efficacy of glycemic control with saxagliptin in older patients (aged ≥ 65 years) with inadequately controlled type 2 diabetes mellitus. Clinical Interventions in Aging 8, pages 419-430.
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Shamsa Ali & Vivian Fonseca. (2013) Saxagliptin overview: special focus on safety and adverse effects. Expert Opinion on Drug Safety 12:1, pages 103-109.
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Michel P. Hermans, Tuncay Delibasi, Ian Farmer, Leif Lohm, Pierre Maheux, PierMarco Piatti, Elmas Malvolti, Silke Jörgens & Bernard Charbonnel. (2012) Effects of saxagliptin added to sub-maximal doses of metformin compared with uptitration of metformin in type 2 diabetes: the PROMPT study. Current Medical Research and Opinion 28:10, pages 1635-1645.
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Anthony H. Barnett, Bernard Charbonnel, Mark Donovan & Douglas Fleming. (2012) Effect of saxagliptin as add-on therapy in patients with poorly controlled type 2 diabetes on insulin alone or insulin combined with metformin. Current Medical Research and Opinion 28:4, pages 513-523.
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Sherwyn L. Schwartz. (2012) Saxagliptin for the treatment of type 2 diabetes mellitus: Focus on recent studies. Annals of Medicine 44:2, pages 157-169.
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Jean Doucet, Antonio Chacra, Pierre Maheux, Jane Lu, Susan Harris & Julio Rosenstock. (2011) Efficacy and safety of saxagliptin in older patients with type 2 diabetes mellitus. Current Medical Research and Opinion 27:4, pages 863-869.
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Paul S. Jellinger. (2011) Focus on Incretin-Based Therapies: Targeting the Core Defects of Type 2 Diabetes. Postgraduate Medicine 123:1, pages 53-65.
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Pasquale J Palumbo & Jonathan M Wert. (2010) Impact of data from recent clinical trials on strategies for treating patients with type 2 diabetes mellitus. Vascular Health and Risk Management 6, pages 17-26.
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James E Foley & Jens Jordan. (2010) Weight neutrality with the DPP-4 inhibitor, vildagliptin: Mechanistic basis and clinical experience. Vascular Health and Risk Management 6, pages 541-548.
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Mary Elizabeth Cox, Jennifer Rowell, Leonor Corsino & Jennifer B Green. (2010) Dipeptidyl peptidase-4 inhibitors in the management of type 2 diabetes: safety, tolerability, and efficacy. Drug, Healthcare and Patient Safety 2, pages 7-19.
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Morali D Sharma. (2010) Role of saxagliptin as monotherapy or adjunct therapy in the treatment of type 2 diabetes. Therapeutics and Clinical Risk Management 6, pages 233-237.
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Baptist Gallwitz. (2010) New treatments in the management of type 2 diabetes: a critical appraisal of saxagliptin. Diabetes, Metabolic Syndrome and Obesity 3, pages 117-124.
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Antonio R Chacra. (2010) Saxagliptin for type 2 diabetes. Diabetes, Metabolic Syndrome and Obesity 3, pages 325-335.
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Julio Rosenstock. (2010) Clinical overview of saxagliptin for Type 2 diabetes management. Expert Review of Endocrinology & Metabolism 5:6, pages 809-823.
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Kaj Stenlöf, Itamar Raz, Joel Neutel, Shoba Ravichandran, Niklas Berglind & Roland Chen. (2010) Saxagliptin and metformin XR combination therapy provides glycemic control over 24 hours in patients with T2DM inadequately controlled with metformin. Current Medical Research and Opinion 26:10, pages 2355-2363.
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Marie T Brown & Derek LeRoith. (2010) Overcoming challenges in Type 2 diabetes management to improve patient outcomes. Expert Review of Endocrinology & Metabolism 5:5, pages 741-751.
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Annie A. Mavian, Stephan Miller & Robert R. Henry. (2010) Managing Type 2 Diabetes: Balancing HbA1c and Body Weight. Postgraduate Medicine 122:3, pages 106-117.
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Priscilla A. Hollander & Pamela Kushner. (2010) Type 2 Diabetes Comorbidities and Treatment Challenges: Rationale for DPP-4 Inhibitors. Postgraduate Medicine 122:3, pages 71-80.
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Louis Kuritzky, Benjamin J. Epstein & Frank Lavernia. (2010) How to Obtain Appropriate Type 2 Diabetes Control in the First 180 Days of Treatment Initiation. Postgraduate Medicine 122:3, pages 33-42.
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Robert Frederich, John H. Alexander, Fred T. Fiedorek, Mark Donovan, Niklas Berglind, Susan Harris, Roland Chen, Robert Wolf & Kenneth W. Mahaffey. (2010) A Systematic Assessment of Cardiovascular Outcomes in the Saxagliptin Drug Development Program for Type 2 Diabetes. Postgraduate Medicine 122:3, pages 16-27.
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Jay H Shubrook, Randall A Colucci & Frank L Schwartz. (2009) Exploration of the DPP-4 inhibitors with a focus on saxagliptin. Expert Opinion on Pharmacotherapy 10:17, pages 2927-2934.
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Anna I. Palalau, Abd A. Tahrani, Milan K. Piya & Anthony H. Barnett. (2009) DPP-4 Inhibitors in Clinical Practice. Postgraduate Medicine 121:6, pages 70-100.
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