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Current Medical Research and Opinion Volume 26, 2010 - Issue 7
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Original Article

Efficacy and safety of a single-pill combination of amlodipine/valsartan in Asian hypertensive patients inadequately controlled with amlodipine monotherapy

YuanNan Ke China-Japan Friendship Hospital, Beijing, ChinaCorrespondence[email protected]
,
DingLiang Zhu Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai, China
,
HuaShan Hong Fujian Medical University Union Hospital, Fuzhou, China
,
JunRen Zhu Zhongshan Hospital, Fudan University, Shanghai, China
,
RuoNan Wang Beijing Novartis Pharma Co Ltd, Beijing, China
,
Pamela Cardenas Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
&
Ying Zhang Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
 show all
Pages 1705-1713 | Accepted 19 Apr 2010, Published online: 14 May 2010

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Shunping Li, Xiaohan Liu & Lanting Li. (2020) A Multicenter Retrospective Analysis on Clinical Effectiveness and Economic Assessment of Compound Reserpine and Hydrochlorothiazide Tablets (CRH) for Hypertension. ClinicoEconomics and Outcomes Research 12, pages 107-114.
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Maodong Ren, Dennis Xuan, Yongji Lu, YuYan Fu & Jianwei Xuan. (2020) Economic evaluation of olmesartan/amlodipine fixed-dose combination for hypertension treatment in China. Journal of Medical Economics 23:4, pages 394-400.
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Yong Huo, Ye Gu, Genshan Ma, Jincheng Guo, Longgen Xiong, Zhurong Luo, Jianhong Xie, Weimin Li, Jianrong Zhao, Xiaowei Yan, Wei Liu, Yawei Xu, Xiaomei Bao, Luosha Zhao, Ming Yang, Bei Wang & The China STATUS III Study Group. (2019) China STudy of valsartan/amlodipine fixed-dose combination-bAsed long-Term blood pressUre management in HypertenSive patients: a one-year registry (China STATUS III). Current Medical Research and Opinion 35:8, pages 1441-1449.
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Sverre E. Kjeldsen, Franz H. Messerli, Chern-En Chiang, Peter A. Meredith & Lisheng Liu. (2012) Are fixed-dose combination antihypertensives suitable as first-line therapy?. Current Medical Research and Opinion 28:10, pages 1685-1697.
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Shu-Meng Cheng, Guang-Yuan Mar, Shih-Chung Huang, Chung-Sen Chen, Chih-Min Hsieh, Lien-Chi Huang & Kwo-Chang Ueng. (2012) Post-marketing surveillance study of valsartan/amlodipine combination in Taiwanese hypertensive patients. Blood Pressure 21:sup1, pages 11-19.
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Articles from other publishers (16)

Mengxin Xie, Tianjiao Tang & Hongsheng Liang. (2023) Efficacy of single‐pill combination in uncontrolled essential hypertension: A systematic review and network meta‐analysis. Clinical Cardiology.
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Shao-Kun Xu, Qi-Fang Huang, Wei-Fang Zeng, Chang-Sheng Sheng, Yan Li & Ji-Guang Wang. (2019) A randomized multicenter study on ambulatory blood pressure and arterial stiffness in patients treated with valsartan/amlodipine or nifedipine GITS. The Journal of Clinical Hypertension 21:2, pages 252-261.
Crossref
Weiliang Zhang, Yongbin Song & Jiangtao Xu. (2017) Effectiveness and safety of valsartan/amlodipine in hypertensive patients with stroke. Medicine 96:26, pages e7172.
Crossref
Ji-Guang Wang, Kimihiko Yukisada, Antonio Sibulo, Kudsia Hafeez, Yan Jia & Jack Zhang. (2017) Efficacy and safety of sacubitril/valsartan (LCZ696) add-on to amlodipine in Asian patients with systolic hypertension uncontrolled with amlodipine monotherapy. Journal of Hypertension 35:4, pages 877-885.
Crossref
T He, X Liu, Y Li, X Y Liu, Q Y Wu, M L Liu & H Yuan. (2016) High-dose calcium channel blocker (CCB) monotherapy vs combination therapy of standard-dose CCBs and angiotensin receptor blockers for hypertension: a meta-analysis. Journal of Human Hypertension 31:2, pages 79-88.
Crossref
Muhammad Ali Sheraz, Syed Furqan Ahsan, Marium Fatima Khan, Sofia Ahmed & Iqbal Ahmad. (2016) Formulations of Amlodipine: A Review. Journal of Pharmaceutics 2016, pages 1-11.
Crossref
Jidong SungJin-Ok JeongSung Uk KwonKyung Heon WonByung Jin KimByung Ryul ChoMyeong-Kon KimSahng LeeHak Jin KimSeong-Hoon LimSeung Woo ParkJeong Euy Park. (2016) Valsartan 160 mg/Amlodipine 5 mg Combination Therapy versus Amlodipine 10 mg in Hypertensive Patients with Inadequate Response to Amlodipine 5 mg Monotherapy. Korean Circulation Journal 46:2, pages 222.
Crossref
Lars C. Rump, Bettina Ammentorp, Petra Laeis & Jürgen Scholze. (2015) Adding Hydrochlorothiazide to Olmesartan/Amlodipine Increases Efficacy in Patients With Inadequate Blood Pressure Control on Dual‐Combination Therapy. The Journal of Clinical Hypertension 18:1, pages 60-69.
Crossref
Beihai Ge, Wenzhong Peng, Yi Zhang, Yuxiang Wen, Cong Liu & Xiaomei Guo. (2015) Effectiveness of Valsartan/Amlodipine Single-pill Combination in Hypertensive Patients With Excess Body Weight. Journal of Cardiovascular Pharmacology 66:5, pages 497-503.
Crossref
Dayi Hu, Lisheng Liu & Weimin Li. (2014) Efficacy and Safety of Valsartan/Amlodipine Single-Pill Combination in 11,422 Chinese Patients with Hypertension: an Observational Study. Advances in Therapy 31:7, pages 762-775.
Crossref
A. Lawrence Gould, S. Unniachan & D. Wu. (2014) Indirect treatment comparison between fixed-dose-combinations of amlodipine/losartan and amlodipine/valsartan in blood pressure control. International Journal of Clinical Practice 68:2, pages 163-172.
Crossref
Keith C. Ferdinand & Samar A. Nasser. (2013) A Review of the Efficacy and Tolerability of Combination Amlodipine/Valsartan in Non-White Patients with Hypertension. American Journal of Cardiovascular Drugs 13:5, pages 301-313.
Crossref
Dingliang Zhu, Kan Yang, Ningling Sun, Pingjin Gao, Ruonan Wang, Amie Grosso & Ying Zhang. (2013) Amlodipine/valsartan 5/160mg versus valsartan 160mg in Chinese hypertensives. International Journal of Cardiology 167:5, pages 2024-2030.
Crossref
Ji-Guang Wang, Wei-Fang Zeng, Yu-Song He, Liang-Long Chen, Meng Wei, Zhao-Ping Li, Bao-Wei Zhang & Yan Li. (2013) Valsartan/Amlodipine Compared to Nifedipine GITS in Patients with Hypertension Inadequately Controlled by Monotherapy. Advances in Therapy 30:8, pages 771-783.
Crossref
Dingliang L. Zhu, Harold Bays, Pingjin Gao, Michaela Mattheus, Birgit Voelker & Luis M. Ruilope. (2012) Efficacy and Tolerability of Initial Therapy With Single-Pill Combination Telmisartan/Hydrochlorothiazide 80/25 mg in Patients With Grade 2 or 3 Hypertension: A Multinational, Randomized, Double-Blind, Active-Controlled Trial. Clinical Therapeutics 34:7, pages 1613-1624.
Crossref
Harikrishna Makani, Sripal Bangalore, Jorge Romero, Nay Htyte, Ronaldo S Berrios, Hetal Makwana & Franz H Messerli. (2011) Peripheral edema associated with calcium channel blockers: incidence and withdrawal rate – a meta-analysis of randomized trials. Journal of Hypertension 29:7, pages 1270-1280.
Crossref

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