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Alberto Leoni, Alessandra Locatelli, Rita Morigi & Mirella Rambaldi. (2014) Novel thiazole derivatives: a patent review (2008 – 2012. Part 2). Expert Opinion on Therapeutic Patents 24:7, pages 759-777.
Read now
Read now
Doris Riether. (2012) Selective cannabinoid receptor 2 modulators: a patent review 2009 – present. Expert Opinion on Therapeutic Patents 22:5, pages 495-510.
Read now
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Praveen PN Rao & Tarek Mohamed. (2011) Current and emerging “at-site” pain medications: a review. Journal of Pain Research 4, pages 279-286.
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Articles from other publishers (70)
Mauro Maccarrone, Vincenzo Di Marzo, Jürg Gertsch, Uwe Grether, Allyn C. Howlett, Tian Hua, Alexandros Makriyannis, Daniele Piomelli, Natsuo Ueda & Mario van der Stelt. (2023) Goods and Bads of the Endocannabinoid System as a Therapeutic Target: Lessons Learned after 30 Years. Pharmacological Reviews 75:5, pages 885-958.
Crossref
Crossref
Zijian Dai, Yiyun Zhang, Yantong Meng, Siqi Li, Zhuoma Suonan, Yuge Sun, Junfu Ji, Qun Shen, Hao Zheng & Yong Xue. (2023) Targeted delivery of nutraceuticals derived from food for the treatment of obesity and its related complications. Food Chemistry 418, pages 135980.
Crossref
Crossref
Kangtai Xu, Yifei Wu, Zhuangzhuang Tian, Yuanfan Xu, Chaoran Wu & Zilong Wang. (2023) Microglial Cannabinoid CB2 Receptors in Pain Modulation. International Journal of Molecular Sciences 24:3, pages 2348.
Crossref
Crossref
Anthony S. Ferranti & Daniel J. Foster. (2022) Cannabinoid type-2 receptors: An emerging target for regulating schizophrenia-relevant brain circuits. Frontiers in Neuroscience 16.
Crossref
Crossref
Martin F. Casey & Alex F. Manini. 2022. Novel Psychoactive Substances. Novel Psychoactive Substances
415
446
.
Laura A. Bryant, Kenneth Shankland, Hannah E. Straker, Callum D. Johnston, Nicholas R. Lees & Alexander J. A. Cobb. (2021)
Enantioselective Organocatalytic Synthesis of Bicyclic Resorcinols
via
an Intramolecular Friedel−Crafts‐Type 1,4‐Addition: Access to Cannabidiol Analogues
. Advanced Synthesis & Catalysis 363:16, pages 4067-4074.
Crossref
Crossref
Benjamin Brennecke, Thais Gazzi, Kenneth Atz, Jürgen Fingerle, Pascal Kuner, Torsten Schindler, Guy de Weck, Marc Nazaré & Uwe Grether. (2021) Cannabinoid receptor type 2 ligands: an analysis of granted patents since 2010. Pharmaceutical Patent Analyst 10:3, pages 111-163.
Crossref
Crossref
Sara Arias, Marta Leon, Diego Jaimes & Rosa-Helena Bustos. (2021) Clinical Evidence of Magistral Preparations Based on Medicinal Cannabis. Pharmaceuticals 14:2, pages 78.
Crossref
Crossref
Bei-Er Jiang, Xingwu Jiang, Qiansen Zhang, Qiuwen Liang, Zi-Liang Qiu, Xiang-Bai Sun, Jun-Jie Yang, Si Chen, Chunyang Yi, Xiaolei Chai, Mingyao Liu, Li-Fang Yu, Weiqiang Lu & Han-Kun Zhang. (2020) From a Designer Drug to the Discovery of Selective Cannabinoid Type 2 Receptor Agonists with Favorable Pharmacokinetic Profiles for the Treatment of Systemic Sclerosis. Journal of Medicinal Chemistry 64:1, pages 385-403.
Crossref
Crossref
Shivani Sachdev, Samuel D. Banister, Marina Santiago, Chris Bladen, Michael Kassiou & Mark Connor. (2020) Differential activation of G protein‐mediated signaling by synthetic cannabinoid receptor agonists. Pharmacology Research & Perspectives 8:2.
Crossref
Crossref
Óscar Díaz, James A. R. Dalton & Jesús Giraldo. (2019) Revealing the Mechanism of Agonist-Mediated Cannabinoid Receptor 1 (CB1) Activation and Phospholipid-Mediated Allosteric Modulation. Journal of Medicinal Chemistry 62:11, pages 5638-5654.
Crossref
Crossref
Thanh C. Ho & Marcus A. Tius. 2019. Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules. Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules
247
289
.
Noureldin Saleh, Oliver Hucke, Gert Kramer, Esther Schmidt, Florian Montel, Radoslaw Lipinski, Boris Ferger, Timothy Clark, Peter W. Hildebrand & Christofer S. Tautermann. (2018) Multiple Binding Sites Contribute to the Mechanism of Mixed Agonistic and Positive Allosteric Modulators of the Cannabinoid CB1 Receptor. Angewandte Chemie International Edition 57:10, pages 2580-2585.
Crossref
Crossref
Noureldin Saleh, Oliver Hucke, Gert Kramer, Esther Schmidt, Florian Montel, Radoslaw Lipinski, Boris Ferger, Timothy Clark, Peter W. Hildebrand & Christofer S. Tautermann. (2018) Multiple Binding Sites Contribute to the Mechanism of Mixed Agonistic and Positive Allosteric Modulators of the Cannabinoid CB1 Receptor. Angewandte Chemie 130:10, pages 2610-2615.
Crossref
Crossref
Samuel D. Banister & Mark Connor. 2018. New Psychoactive Substances. New Psychoactive Substances
165
190
.
Simone Bertini, Andrea Chicca, Francesca Gado, Chiara Arena, Daniela Nieri, Maria Digiacomo, Giuseppe Saccomanni, Pingwei Zhao, Mary E. Abood, Marco Macchia, Jürg Gertsch & Clementina Manera. (2017) Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor. Bioorganic & Medicinal Chemistry 25:24, pages 6427-6434.
Crossref
Crossref
Robert B. Laprairie, Pushkar M. Kulkarni, Jeffrey R. Deschamps, Melanie E. M. Kelly, David R. Janero, Maria G. CascioLesley A. StevensonRoger G. PertweeTerrence P. Kenakin, Eileen M. Denovan-Wright & Ganesh A. Thakur. (2017) Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor. ACS Chemical Neuroscience 8:6, pages 1188-1203.
Crossref
Crossref
Pushkar M. Kulkarni, Ameya Ranade, Sumanta Garai & Ganesh A. Thakur. (2017) Microwave‐accelerated Conjugate Addition of 2‐Arylindoles to Substituted β‐Nitrostyrenes in the Presence of Ammonium Trifluoroacetate: An Efficient Approach for the Synthesis of a Novel Class of CB1 Cannabinoid Receptor Allosteric Modulators. Journal of Heterocyclic Chemistry 54:3, pages 2079-2084.
Crossref
Crossref
Marjolein Soethoudt, Uwe Grether, Jürgen Fingerle, Travis W. Grim, Filomena Fezza, Luciano de Petrocellis, Christoph Ullmer, Benno Rothenhäusler, Camille Perret, Noortje van Gils, David Finlay, Christa MacDonald, Andrea Chicca, Marianela Dalghi Gens, Jordyn Stuart, Henk de Vries, Nicolina Mastrangelo, Lizi Xia, Georgios Alachouzos, Marc P. Baggelaar, Andrea Martella, Elliot D. Mock, Hui Deng, Laura H. Heitman, Mark Connor, Vincenzo Di Marzo, Jürg Gertsch, Aron H. Lichtman, Mauro Maccarrone, Pal Pacher, Michelle Glass & Mario van der Stelt. (2017) Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity. Nature Communications 8:1.
Crossref
Crossref
Abhijit R. Kulkarni, Sumanta Garai, David R. Janero & Ganesh A. Thakur. 2017. Cannabinoids and Their Receptors. Cannabinoids and Their Receptors
281
315
.
M.H. Ahmed & Y. Zhang. 2017. Handbook of Cannabis and Related Pathologies. Handbook of Cannabis and Related Pathologies
680
690
.
Torbjörn U.C. Järbe, Brian J. LeMay, Ganesh A. Thakur & Alexandros Makriyannis. (2016) A high efficacy cannabinergic ligand (AM4054) used as a discriminative stimulus: Generalization to other adamantyl analogs and Δ 9 -THC in rats. Pharmacology Biochemistry and Behavior 148, pages 46-52.
Crossref
Crossref
Robert B. Laprairie, Abhijit R. Kulkarni, Pushkar M. Kulkarni, Dow P. Hurst, Diane Lynch, Patricia H. Reggio, David R. Janero, Roger G. Pertwee, Lesley A. Stevenson, Melanie E. M. Kelly, Eileen M. Denovan-Wright & Ganesh A. Thakur. (2016) Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe. ACS Chemical Neuroscience 7:6, pages 776-798.
Crossref
Crossref
Christel A.S. Bergström, William N. Charman & Christopher J.H. Porter. (2016) Computational prediction of formulation strategies for beyond-rule-of-5 compounds. Advanced Drug Delivery Reviews 101, pages 6-21.
Crossref
Crossref
Pushkar M. Kulkarni, Abhijit R. Kulkarni, Anisha Korde, Ritesh B. Tichkule, Robert B. Laprairie, Eileen M. Denovan-Wright, Han Zhou, David R. Janero, Nikolai Zvonok, Alexandros Makriyannis, Maria G. Cascio, Roger G. Pertwee & Ganesh A. Thakur. (2015) Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s). Journal of Medicinal Chemistry 59:1, pages 44-60.
Crossref
Crossref
Ruben Vardanyan & Victor Hruby. 2016. Synthesis of Best-Seller Drugs. Synthesis of Best-Seller Drugs
15
64
.
Matthias Nettekoven, Jean-Michel Adam, Stefanie Bendels, Catarina Bissantz, Jürgen Fingerle, Uwe Grether, Sabine Grüner, Wolfgang Guba, Atsushi Kimbara, Giorgio Ottaviani, Bernd Püllmann, Mark Rogers-Evans, Stephan Röver, Benno Rothenhäusler, Sebastien Schmitt, Franz Schuler, Tanja Schulz-Gasch & Christoph Ullmer. (2016) Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists as Potential Treatment for Inflammatory Kidney Diseases. ChemMedChem 11:2, pages 179-189.
Crossref
Crossref
Oscar Delgado, Francisca Delgado, Juan Antonio Vega & Andrés A. Trabanco. (2015) N-bridged 5,6-bicyclic pyridines: Recent applications in central nervous system disorders. European Journal of Medicinal Chemistry 97, pages 719-731.
Crossref
Crossref
V Kiran Vemuri & A Makriyannis. (2015) Medicinal chemistry of cannabinoids. Clinical Pharmacology & Therapeutics 97:6, pages 553-558.
Crossref
Crossref
Amine Bahi, Shamma Al Mansouri, Elyazia Al Memari, Mouza Al Ameri, Syed M Nurulain & Shreesh Ojha. (2014) β-Caryophyllene, a CB2 receptor agonist produces multiple behavioral changes relevant to anxiety and depression in mice. Physiology & Behavior 135, pages 119-124.
Crossref
Crossref
Shuang Han, Fei-Fei Zhang, Xin Xie & Jian-Zhong Chen. (2014) Design, synthesis, biological evaluation, and comparative docking study of 1,2,4-triazolones as CB1 receptor selective antagonists. European Journal of Medicinal Chemistry 74, pages 73-84.
Crossref
Crossref
Mostafa H. Ahmed, Glen E. Kellogg, Dana E. Selley, Martin K. Safo & Yan Zhang. (2014) Predicting the molecular interactions of CRIP1a–cannabinoid 1 receptor with integrated molecular modeling approaches. Bioorganic & Medicinal Chemistry Letters 24:4, pages 1158-1165.
Crossref
Crossref
Kausik K. Nanda, Darrell A. Henze, Kimberly Della Penna, Reshma Desai, Michael Leitl, Wei Lemaire, Rebecca B. White, Suzie Yeh, Janine N. Brouillette, George D. Hartman, Mark T. Bilodeau & B. Wesley Trotter. (2014) Benzimidazole CB2 agonists: Design, synthesis and SAR. Bioorganic & Medicinal Chemistry Letters 24:4, pages 1218-1221.
Crossref
Crossref
Rodrigo Teodoro, Rareş-Petru Moldovan, Corinna Lueg, Robert Günther, Cornelius K Donat, Friedrich-Alexander Ludwig, Steffen Fischer, Winnie Deuther-Conrad, Bernhard Wünsch & Peter Brust. (2013) Radiofluorination and biological evaluation of N-aryl-oxadiazolyl-propionamides as potential radioligands for PET imaging of cannabinoid CB2 receptors. Organic and Medicinal Chemistry Letters 3:1.
Crossref
Crossref
Sean P. Hollinshead, Michael W. Tidwell, John Palmer, Rossella GuidettiAdam SandersonMichael P. Johnson, Mark G. Chambers, Jennifer Oskins, Robert Stratford & Peter C. Astles. (2013) Selective Cannabinoid Receptor Type 2 (CB2) Agonists: Optimization of a Series of Purines Leading to the Identification of a Clinical Candidate for the Treatment of Osteoarthritic Pain. Journal of Medicinal Chemistry 56:14, pages 5722-5733.
Crossref
Crossref
Ganesh A. Thakur, Shama Bajaj, Carol Paronis, Yan Peng, Anna L. Bowman, Lawrence S. Barak, Marc G. Caron, Demon Parrish, Jeffrey R. Deschamps & Alexandros Makriyannis. (2013) Novel Adamantyl Cannabinoids as CB1 Receptor Probes. Journal of Medicinal Chemistry 56:10, pages 3904-3921.
Crossref
Crossref
Ken-ichi Kusakabe, Yukio Tada, Yasuyoshi Iso, Masahiro Sakagami, Yasuhide Morioka, Nobuo Chomei, Satomi Shinonome, Keiko Kawamoto, Hideyuki Takenaka, Kiyoshi Yasui, Hiroshi Hamana & Kohji Hanasaki. (2013) Design, synthesis, and binding mode prediction of 2-pyridone-based selective CB2 receptor agonists. Bioorganic & Medicinal Chemistry 21:7, pages 2045-2055.
Crossref
Crossref
Matthias Nettekoven, Jürgen Fingerle, Uwe Grether, Sabine Grüner, Atsushi Kimbara, Bernd Püllmann, Mark Rogers-Evans, Stephan Röver, Franz Schuler, Tanja Schulz-Gasch & Christoph Ullmer. (2013) Highly potent and selective cannabinoid receptor 2 agonists: Initial hit optimization of an adamantyl hit series identified from high-through-put screening. Bioorganic & Medicinal Chemistry Letters 23:5, pages 1177-1181.
Crossref
Crossref
Alleyn T. Plowright, Karolina Nilsson, Madeleine Antonsson, Kosrat Amin, Johan Broddefalk, Jörgen Jensen, Anders Lehmann, Shujuan Jin, Stephane St-Onge, Mirosław J. Tomaszewski, Maxime Tremblay, Christopher Walpole, Zhongyong Wei, Hua Yang & Johan Ulander. (2012) Discovery of Agonists of Cannabinoid Receptor 1 with Restricted Central Nervous System Penetration Aimed for Treatment of Gastroesophageal Reflux Disease. Journal of Medicinal Chemistry 56:1, pages 220-240.
Crossref
Crossref
Volker Auwärter, Paul I. Dargan & David M. Wood. 2013. Novel Psychoactive Substances. Novel Psychoactive Substances
317
343
.
Viktor Rempel, Nicole Volz, Sonja Hinz, Tadeusz Karcz, Irene Meliciani, Martin Nieger, Wolfgang Wenzel, Stefan Bräse & Christa E. Müller. (2012) 7-Alkyl-3-benzylcoumarins: A Versatile Scaffold for the Development of Potent and Selective Cannabinoid Receptor Agonists and Antagonists. Journal of Medicinal Chemistry 55:18, pages 7967-7977.
Crossref
Crossref
V. Auwärter, S. Kneisel, M. Hutter & A. Thierauf. (2012) Synthetische CannabinoideSynthetic cannabinoids. Rechtsmedizin 22:4, pages 259-271.
Crossref
Crossref
E. J. GILBERT & C. A. LUNN. 2012. Anti-Inflammatory Drug Discovery. Anti-Inflammatory Drug Discovery
391
413
.
Brady K. Atwood, Alex Straiker & Ken Mackie. (2012) CB2: Therapeutic target-in-waiting. Progress in Neuro-Psychopharmacology and Biological Psychiatry 38:1, pages 16-20.
Crossref
Crossref
A. O. Cox, R. C. Daw, M. D. Mason, M. Grabenauer, P. G. Pande, K. H. Davis, J. L. Wiley, P. R. Stout, B. F. Thomas & J. W. Huffman. (2012) Use of SPME-HS-GC-MS for the Analysis of Herbal Products Containing Synthetic Cannabinoids. Journal of Analytical Toxicology 36:5, pages 293-302.
Crossref
Crossref
Zhushou Luo & Mohamed Naguib. (2012) A synthetic approach for (S)-(3-benzyl-3-methyl-2,3-dihydro-benzofuran-6-yl)-piperidin-1-yl-methanone, a selective CB2 receptor agonist. Tetrahedron Letters 53:26, pages 3316-3318.
Crossref
Crossref
Jenny L. Wilkerson, Katherine R. Gentry, Ellen C. Dengler, James A. Wallace, Audra A. Kerwin, Megan N. Kuhn, Alexander M. Zvonok, Ganesh A. Thakur, Alexandros Makriyannis & Erin D. Milligan. (2012) Immunofluorescent spectral analysis reveals the intrathecal cannabinoid agonist, AM1241, produces spinal anti‐inflammatory cytokine responses in neuropathic rats exhibiting relief from allodynia. Brain and Behavior 2:2, pages 155-177.
Crossref
Crossref
Yun-Xing Cheng, Mehrnaz Pourashraf, Xuehong Luo, Sanjay Srivastava, Christopher Walpole, Dominic Salois, Stephane St-Onge, Kemal Payza, Etienne Lessard, Xiao Hong Yu & Mirosław J. Tomaszewski. (2012) γ-Carbolines: A novel class of cannabinoid agonists with high aqueous solubility and restricted CNS penetration. Bioorganic & Medicinal Chemistry Letters 22:4, pages 1619-1624.
Crossref
Crossref
Stefan Mergler, Yating Cheng, Sergej Skosyrski, Fabian Garreis, Piotr Pietrzak, Norbert Kociok, Abhilash Dwarakanath, Peter S. Reinach & Vinodh Kakkassery. (2012) Altered calcium regulation by thermosensitive transient receptor potential channels in etoposide-resistant WERI-Rb1 retinoblastoma cells. Experimental Eye Research 94:1, pages 157-173.
Crossref
Crossref
Harrie J.M. Gijsen, Michel A.J. De Cleyn, Michel Surkyn, Guy R.E. Van Lommen, Bie M.P. Verbist, Marjoleen J.M.A. Nijsen, Theo Meert, Jean Van Wauwe & Jeroen Aerssens. (2012) 5-Sulfonyl-benzimidazoles as selective CB2 agonists-Part 2. Bioorganic & Medicinal Chemistry Letters 22:1, pages 547-552.
Crossref
Crossref
Stefan Engeli. 2012. Appetite Control. Appetite Control
357
381
.
Jenny L. Wilkerson & Erin D. Milligan. (2011) The Central Role of Glia in Pathological Pain and the Potential of Targeting the Cannabinoid 2 Receptor for Pain Relief. ISRN Anesthesiology 2011, pages 1-19.
Crossref
Crossref
Aoife Gowran, Janis Noonan & Veronica A. Campbell. (2011) The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration. CNS Neuroscience & Therapeutics 17:6, pages 637-644.
Crossref
Crossref
Lev Osherovich. (2011) FLATtening pain. Science-Business eXchange 4:47, pages 1314-1314.
Crossref
Crossref
Mario van der Stelt, Jos Cals, Silvia Broeders-Josten, Jean Cottney, Antoon A. van der Doelen, Marcel Hermkens, Vera de Kimpe, Angela King, Jan Klomp, Julia Oosterom, Ilse Pols-de Rooij, Jeroen de Roos, Martin van Tilborg, Susan Boyce & James Baker. (2011) Discovery and Optimization of 1-(4-(Pyridin-2-yl)benzyl)imidazolidine-2,4-dione Derivatives As a Novel Class of Selective Cannabinoid CB2 Receptor Agonists. Journal of Medicinal Chemistry 54:20, pages 7350-7362.
Crossref
Crossref
Marion Feledziak, Giulio G. Muccioli, Didier M. Lambert & Jacqueline Marchand-Brynaert. (2011)
SAR and LC/MS Studies of β-Lactamic Inhibitors of Human Fatty Acid Amide Hydrolase (
h
FAAH): Evidence of a Nonhydrolytic Process
. Journal of Medicinal Chemistry 54:19, pages 6812-6823.
Crossref
Crossref
Kathleen M. Bisset, Amey S. Dhopeshwarkar, Chengyong Liao & Russell A. Nicholson. (2011) The G protein-coupled cannabinoid-1 (CB1) receptor of mammalian brain: Inhibition by phthalate esters in vitro. Neurochemistry International 59:5, pages 706-713.
Crossref
Crossref
Antoni R. Blaazer, Jos H.M. Lange, Martina A.W. van der Neut, Arie Mulder, Femke S. den Boon, Taco R. Werkman, Chris G. Kruse & Wytse J. Wadman. (2011) Novel indole and azaindole (pyrrolopyridine) cannabinoid (CB) receptor agonists: Design, synthesis, structure–activity relationships, physicochemical properties and biological activity. European Journal of Medicinal Chemistry 46:10, pages 5086-5098.
Crossref
Crossref
Heidi Teng, Ganesh A. Thakur & Alexandros Makriyannis. (2011) Conformationally constrained analogs of BAY 59–3074 as novel cannabinoid receptor ligands. Bioorganic & Medicinal Chemistry Letters 21:19, pages 5999-6002.
Crossref
Crossref
Xiaoyu Tian, Spiro Pavlopoulos, De-Ping Yang & Alexandros Makriyannis. (2011) The interaction of cannabinoid receptor agonists, CP55940 and WIN55212-2 with membranes using solid state 2H NMR. Biochimica et Biophysica Acta (BBA) - Biomembranes 1808:9, pages 2095-2101.
Crossref
Crossref
Yihong Fan, Bradley A. Hooker, Tiffany Runyan Garrison, Odile F. El-Kouhen, Kenneth B. Idler, Rhonda R. Holley-Shanks, Michael D. Meyer & Betty Bei Yao. (2011) Pharmacological and molecular characterization of a dorsal root ganglion cell line expressing cannabinoid CB1 and CB2 receptors. European Journal of Pharmacology 659:2-3, pages 161-168.
Crossref
Crossref
Michelle Sexton, Grace Woodruff, Eric A. Horne, Yi Hsing Lin, Giulio G. Muccioli, Mingfeng Bai, Eric Stern, Darryl J. Bornhop & Nephi Stella. (2011) NIR-mbc94, a Fluorescent Ligand that Binds to Endogenous CB2 Receptors and Is Amenable to High-Throughput Screening. Chemistry & Biology 18:5, pages 563-568.
Crossref
Crossref
Ester M. López, Patricia Tagliaferro, Emmanuel S. Onaivi & Juan J. López-Costa. (2011) Distribution of CB2 cannabinoid receptor in adult rat retina. Synapse 65:5, pages 388-392.
Crossref
Crossref
B. Wesley Trotter, Kausik K. Nanda, Christopher S. Burgey, Craig M. Potteiger, James Z. Deng, Ahren I. Green, John C. Hartnett, Nathan R. Kett, Zhicai Wu, Darrell A. Henze, Kimberly Della Penna, Reshma Desai, Michael D. Leitl, Wei Lemaire, Rebecca B. White, Suzie Yeh, Mark O. Urban, Stefanie A. Kane, George D. Hartman & Mark T. Bilodeau. (2011) Imidazopyridine CB2 agonists: Optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy. Bioorganic & Medicinal Chemistry Letters 21:8, pages 2354-2358.
Crossref
Crossref
Peter J. Manley, Amy Zartman, Daniel V. Paone, Christopher S. Burgey, Darrell A. Henze, Kimberly Della Penna, Reshma Desai, Michael D. Leitl, Wei Lemaire, Rebecca B. White, Suzie Yeh, Mark O. Urban, Stefanie A. Kane, George D. Hartman, Mark T. Bilodeau & B. Wesley Trotter. (2011) Decahydroquinoline amides as highly selective CB2 agonists: Role of selectivity on in vivo efficacy in a rodent model of analgesia. Bioorganic & Medicinal Chemistry Letters 21:8, pages 2359-2364.
Crossref
Crossref
Elizabeth M. Moir, Kazuya Yoshiizumi, Jim Cairns, Phillip Cowley, Morag Ferguson, Fiona Jeremiah, Takao Kiyoi, Richard Morphy, Jason Tierney, Grant Wishart, Mark York, James Baker, Jean E. Cottney, Andrea K. Houghton, Petula McPhail, Andrew Osprey, Glenn Walker & Julia M. Adam. (2010) Design, synthesis, and structure–activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists. Bioorganic & Medicinal Chemistry Letters 20:24, pages 7327-7330.
Crossref
Crossref
Jos H.M. Lange, Amos Attali, Martina A.W. van der Neut, Henri C. Wals, Arie Mulder, Hicham Zilaout, Ate Duursma, Hans H.M. van Aken & Bernard J. van Vliet. (2010) Two distinct classes of novel pyrazolinecarboxamides as potent cannabinoid CB1 receptor agonists. Bioorganic & Medicinal Chemistry Letters 20:17, pages 4992-4998.
Crossref
Crossref
Santhi Gorantla, Edward Makarov, Deepa Roy, Jennifer Finke-Dwyer, L. Charles Murrin, Howard E. Gendelman & Larisa Poluektova. (2010) Immunoregulation of a CB2 Receptor Agonist in a Murine Model of NeuroAIDS. Journal of Neuroimmune Pharmacology 5:3, pages 456-468.
Crossref
Crossref
Jos H.M. Lange, Martina A.W. van der Neut, Henri C. Wals, Gijs D. Kuil, Alice J.M. Borst, Arie Mulder, Arnold P. den Hartog, Hicham Zilaout, Wouter Goutier, Herman H. van Stuivenberg & Bernard J. van Vliet. (2010) Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB2 receptor antagonists with high binding efficiencies. Bioorganic & Medicinal Chemistry Letters 20:3, pages 1084-1089.
Crossref
Crossref
Julia M. Adam, Jim Cairns, Wilson Caulfield, Phillip Cowley, Iain Cumming, Morag Easson, Darren Edwards, Morag Ferguson, Richard Goodwin, Fiona Jeremiah, Takao Kiyoi, Ashvin Mistry, Elizabeth Moir, Richard Morphy, Jason Tierney, Mark York, James Baker, Jean E. Cottney, Andrea K. Houghton, Paul J. Westwood & Glenn Walker. (2010) Design, synthesis, and structure–activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists. MedChemComm 1:1, pages 54.
Crossref
Crossref