Citations (111)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (9)
Amirhossein Sheida, Tarannomsadat Taghavi, Rana Shafabakhsh, Amirreza Ostadian, Zahra Razaghi Bahabadi, Mahmood Khaksary Mahabady, Michael R Hamblin & Hamed Mirzaei. (2023) Potential of natural products in the treatment of myocardial infarction: focus on molecular mechanisms. Critical Reviews in Food Science and Nutrition 63:22, pages 5488-5505.
Read now
Read now
Francesca Arrighi, Arianna Granese, Paola Chimenti & Paolo Guglielmi. (2023) Novel therapeutic opportunities for Toxoplasma gondii, Trichomonas vaginalis, and Giardia intestinalis infections. Expert Opinion on Therapeutic Patents 33:3, pages 211-245.
Read now
Read now
Meiqi Zhang, Yun Chen, Huan Chen, Ye Shen, Lingxiao Pang, Weihua Wu & Zhenfei Yu. (2022) Tanshinone IIA alleviates cardiac hypertrophy through m6A modification of galectin-3. Bioengineered 13:2, pages 4260-4270.
Read now
Read now
Feng Gao, Ming Li, Wenbin Liu & Wei Li. (2020) Inhibition of EGFR Signaling and Activation of Mitochondrial Apoptosis Contribute to Tanshinone IIA-Mediated Tumor Suppression in Non-Small Cell Lung Cancer Cells. OncoTargets and Therapy 13, pages 2757-2769.
Read now
Read now
Rui Guo, Lan Li, Jing Su, Sheng Li, Sophia Esi Duncan, Zhihao Liu & Guanwei Fan. (2020) Pharmacological Activity and Mechanism of Tanshinone IIA in Related Diseases. Drug Design, Development and Therapy 14, pages 4735-4748.
Read now
Read now
Hong Xu, Haiqing Li, Pengxiong Zhu, Yun Liu, Mi Zhou & Anqing Chen. (2020) Tanshinone IIA Ameliorates Progression of CAD Through Regulating Cardiac H9c2 Cells Proliferation and Apoptosis by miR-133a-3p/EGFR Axis. Drug Design, Development and Therapy 14, pages 2853-2863.
Read now
Read now
Shihao You, Xianghui He, Mei Wang, Lina Mao & Lu Zhang. (2020) Tanshinone IIA Suppresses Glioma Cell Proliferation, Migration and Invasion Both in vitro and in vivo Partially Through miR-16-5p/Talin-1 (TLN1) Axis. Cancer Management and Research 12, pages 11309-11320.
Read now
Read now
Jiao-Jiao Wu, Neng Gan, Li Hu, Shan-Shan Chen, Hong-Chun Pan & Hong Liu. (2017) Effect of lyophilization process on the physical properties and stability of tanshinone IIA microemulsions. Drying Technology 35:10, pages 1225-1233.
Read now
Read now
Yuee Cai, Wenji Zhang, Zirong Chen, Zhi Shi, Chengwei He & Meiwan Chen. (2016) Recent insights into the biological activities and drug delivery systems of tanshinones. International Journal of Nanomedicine 11, pages 121-130.
Read now
Read now
Articles from other publishers (102)
Fahimeh Rastegarnejad, Mohammad Hossein Mirjalili & Ziba Bakhtiar. (2023) Enhanced production of tanshinone and phenolic compounds in hairy roots culture of Salvia miltiorrhiza Bunge by elicitation. Plant Cell, Tissue and Organ Culture (PCTOC) 156:1.
Crossref
Crossref
Qi Wu, Yu-bo Guan, Ke-jia Zhang, Li Li & Yao Zhou. (2023) Tanshinone IIA mediates protection from diabetes kidney disease by inhibiting oxidative stress induced pyroptosis. Journal of Ethnopharmacology 316, pages 116667.
Crossref
Crossref
Kajal sherawat & Sidharth Mehan. (2023) Tanshinone-IIA mediated neuroprotection by modulating neuronal pathways. Naunyn-Schmiedeberg's Archives of Pharmacology 396:8, pages 1647-1667.
Crossref
Crossref
Wenwen Zhang, Meihua Liu, Yurou Ji, Dake Yu, Chuanrui Ma, Jianguo Zhao & Pengpeng Qu. (2023) Tanshinone IIA inhibits endometrial carcinoma growth through the MAPK/ERK/TRIB3 pathway. Archives of Biochemistry and Biophysics 743, pages 109655.
Crossref
Crossref
Aanchal Verma, Khushbu Kumari, Parag Varshney & Ahsas Goyal. (2023) Pharmacological Actions of Tanshinone IIA with Special Focus on Nrf-2 Signaling Pathway. Revista Brasileira de Farmacognosia.
Crossref
Crossref
Jie Wang, Yong-Mei Liu, Jun Hu & Cong Chen. (2023) Potential of natural products in combination with arsenic trioxide: Investigating cardioprotective effects and mechanisms. Biomedicine & Pharmacotherapy 162, pages 114464.
Crossref
Crossref
Xu Deng, Su-Ling Huang, Jian Ren, Zheng-Hong Pan, Yu Shen, Hao-Feng Zhou, Zhi-Li Zuo, Ying Leng & Qin-Shi Zhao. (2022) Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors. Natural Products and Bioprospecting 12:1.
Crossref
Crossref
Yanyun Zhou, Hong Zhang, Yitong Huang, Shengyun Wu & Zongjun Liu. (2022) Tanshinone IIA regulates expression of glucose transporter 1 via activation of the HIF‑1α signaling pathway. Molecular Medicine Reports 26:5.
Crossref
Crossref
Jie Liu, Yong-hong Wu, Zheng-liang Zhang & Ping Li. (2022) Tanshinone IIA improves sepsis-induced acute lung injury through the ROCK2/NF-κB axis. Toxicology and Applied Pharmacology 446, pages 116021.
Crossref
Crossref
Lung-Shuo Wang, Pei-Tzu Yen, Shih-Feng Weng, Jong-Hau Hsu & Jwu-Lai Yeh. (2022) Clinical Patterns of Traditional Chinese Medicine for Ischemic Heart Disease Treatment: A Population-Based Cohort Study. Medicina 58:7, pages 879.
Crossref
Crossref
Jing-jing Tang, Guang-xi Li, Zhi-guo Liu, Rong Yi, Dong Yu, Yue-bo Zhang, Shuang-qiao Zhao & Shi-han Wang. (2020) Danlou Tablet Improves Chronic Intermittent Hypoxia-Induced Dyslipidemia and Arteriosclerosis by HIF-1α-Angptl4 mRNA Signaling Pathway. Chinese Journal of Integrative Medicine 28:6, pages 509-517.
Crossref
Crossref
Amira A. El-Gazar, Ayat M. Emad, Ghada M. Ragab & Dalia M. Rasheed. (2022) Mentha pulegium L. (Pennyroyal, Lamiaceae) Extracts Impose Abortion or Fetal-Mediated Toxicity in Pregnant Rats; Evidenced by the Modulation of Pregnancy Hormones, MiR-520, MiR-146a, TIMP-1 and MMP-9 Protein Expressions, Inflammatory State, Certain Related Signaling Pathways, and Metabolite Profiling via UPLC-ESI-TOF-MS. Toxins 14:5, pages 347.
Crossref
Crossref
Xiaoyong Tang, Chao Chen, Guangqing Cheng, Yan Chen, Changsheng Li & Xiaoni Yang. (2022) Prognostic Values of Tanshinone in Mediating the Activity of Human Umbilical Vein Endothelial Cells. International Journal of Pharmacology 18:5, pages 983-993.
Crossref
Crossref
Nan Wei, Lizhou Wang, Min Xu, Tianzhi An, Xueqing Huang & Shi Zhou. (2022) Research on mechanism of tanshinone a in regulating biological characteristics of hematopoietic stem cell in liver cirrhosis through targeting of miR-9a-5p. Materials Express 12:5, pages 653-659.
Crossref
Crossref
Tsuo-Cheng Lu, Yi-Hsiu Wu, Wei-Yu Chen & Yu-Chiang Hung. (2022) Targeting Oxidative Stress and Endothelial Dysfunction Using Tanshinone IIA for the Treatment of Tissue Inflammation and Fibrosis. Oxidative Medicine and Cellular Longevity 2022, pages 1-20.
Crossref
Crossref
L Liu, Y Yang, W Li, Y Li, X Jiang & L Wang. (2022) Tanshinone IIA alleviate rifampicin-induced cholestasis by regulating the expression and function of bile salt export pump. Human & Experimental Toxicology 41, pages 096032712210973.
Crossref
Crossref
Hongxia Li, Mingyu Wu, Congying Guo, Rao Zhai & Jun Chen. (2022) Tanshinone IIA Regulates Keap1/Nrf2 Signal Pathway by Activating Sestrin2 to Restrain Pulmonary Fibrosis. The American Journal of Chinese Medicine 50:08, pages 2125-2151.
Crossref
Crossref
Wenfeng Zhang, Cun Liu, Jie Li, Yiping Lu, Huayao Li, Jing Zhuang, Xin Ren, Mengmeng Wang & Changgang Sun. (2022) Tanshinone IIA: New Perspective on the Anti-Tumor Mechanism of A Traditional Natural Medicine. The American Journal of Chinese Medicine 50:01, pages 209-239.
Crossref
Crossref
He Huang, Yongfang Yao, Guodong Hou, Cui Zhao, Jinling Qin, Yixin Zhang, Yongtao Duan, Chuanjun Song & Junbiao Chang. (2021) Design, synthesis and biological evaluation of tanshinone IIA-based analogues: Potent inhibitors of microtubule formation and angiogenesis. European Journal of Medicinal Chemistry 224, pages 113708.
Crossref
Crossref
Sushma Mishra, Pramod Kumar Sahu, Vishad Agarwal & Namrata Singh. (2021) Exploiting endophytic microbes as micro-factories for plant secondary metabolite production. Applied Microbiology and Biotechnology 105:18, pages 6579-6596.
Crossref
Crossref
Lalita Subedi & Bhakta Prasad Gaire. (2021) Tanshinone IIA: A phytochemical as a promising drug candidate for neurodegenerative diseases. Pharmacological Research 169, pages 105661.
Crossref
Crossref
Qiaojing Yan, Zhimin Mao, Jingru Hong, Kun Gao, Manabu Niimi, Takahiko Mitsui & Jian Yao. (2021) Tanshinone IIA Stimulates Cystathionine γ-Lyase Expression and Protects Endothelial Cells from Oxidative Injury. Antioxidants 10:7, pages 1007.
Crossref
Crossref
Sophia Ogechi Ekeuku, Kok-Lun Pang & Kok-Yong Chin. (2021) The Skeletal Effects of Tanshinones: A Review. Molecules 26:8, pages 2319.
Crossref
Crossref
Alessandro Allegra, Chiara Imbesi, Alessandra Bitto & Roberta Ettari. (2021) Drug Repositioning for the Treatment of Hematologic Disease: Limits, Challenges and Future Perspectives. Current Medicinal Chemistry 28:11, pages 2195-2217.
Crossref
Crossref
Huaian LinYifan ZhangLi YuDanning ZhengJuan An. (2021) Salvia miltiorrhiza Injection Promotes the Adipogenic Differentiation of Human Adipose-Derived Stem Cells. Plastic & Reconstructive Surgery 147:3, pages 613-624.
Crossref
Crossref
Heng Zou, Yanli Li, Xiaomin Liu, Zong Wu, Jingjing Li & Zhongliang Ma. (2020)
Roles of plant‐derived bioactive compounds and related
microRNAs
in cancer therapy
. Phytotherapy Research 35:3, pages 1176-1186.
Crossref
Crossref
Sepideh Mirzaei, Ali Zarrabi, Farid Hashemi, Amirhossein Zabolian, Hossein Saleki, Negar Azami, Soodeh Hamzehlou, Mahdi Vasheghani Farahani, Kiavash Hushmandi, Milad Ashrafizadeh, Haroon Khan & Alan Prem Kumar. (2021) Nrf2 Signaling Pathway in Chemoprotection and Doxorubicin Resistance: Potential Application in Drug Discovery. Antioxidants 10:3, pages 349.
Crossref
Crossref
Hadi Mohsenpour, Mirko Pesce, Antonia Patruno, Azam Bahrami, Pardis Mohammadi Pour & Mohammad Hosein Farzaei. (2021) A Review of Plant Extracts and Plant-Derived Natural Compounds in the Prevention/Treatment of Neonatal Hypoxic-Ischemic Brain Injury. International Journal of Molecular Sciences 22:2, pages 833.
Crossref
Crossref
Tianpeng Chen, Gaoyang Zhu, Xiangwei Meng & Xingxian Zhang. (2020) Recent developments of small molecules with anti-inflammatory activities for the treatment of acute lung injury. European Journal of Medicinal Chemistry 207, pages 112660.
Crossref
Crossref
Aml Ghanem, Hamdy A. Emara, Shaden Muawia, Ahmed I. Abd El Maksoud, Ahmed A. Al-Karmalawy & Mohamed F. Elshal. (2020)
Tanshinone IIA synergistically enhances the antitumor activity of doxorubicin by interfering with the PI3K/AKT/mTOR pathway and inhibition of topoisomerase II:
in vitro
and molecular docking studies
. New Journal of Chemistry 44:40, pages 17374-17381.
Crossref
Crossref
Yang Ma, Wenjun Wang, Jiani Yang, Sha Zhang, Zhe Li, Fei Li, Shaojie Huang, Lu Lei, Kai Wang, Aidong Wen & Yi Ding. (2020) A Network Pharmacology Technique to Investigate the Synergistic Mechanisms of Salvia miltiorrhiza and Radix puerariae in Treatment of Cardio-Cerebral Vascular Diseases. Evidence-Based Complementary and Alternative Medicine 2020, pages 1-18.
Crossref
Crossref
Yalan Wu, Suowen Xu & Xiao Yu Tian. (2020) The Effect of Salvianolic Acid on Vascular Protection and Possible Mechanisms. Oxidative Medicine and Cellular Longevity 2020, pages 1-9.
Crossref
Crossref
Xiaozhong Liao, Ying Gao, Jiahui Liu, Lanting Tao, Dongmei Wang, Dan Xie & Suilin Mo. (2020) Combination of Tanshinone IIA and Cisplatin Inhibits Esophageal Cancer by Downregulating NF-κB/COX-2/VEGF Pathway. Frontiers in Oncology 10.
Crossref
Crossref
He Huang, Chuanjun Song, Zhen Wang, Mengyang Li & Junbiao Chang. (2020) Total synthesis of tanshinone IIA. Tetrahedron Letters 61:28, pages 152102.
Crossref
Crossref
Junjian Wang, Rui Hu, Chunyan Yin & Yanfeng Xiao. (2019) Tanshinone IIA reduces palmitate‐induced apoptosis via inhibition of endoplasmic reticulum stress in HepG2 liver cells. Fundamental & Clinical Pharmacology 34:2, pages 249-262.
Crossref
Crossref
Yingxue Li, Bo Jiang, Ruiyin Wang, Jingyun Wang, Yachen Li & Yongming Bao. (2020) Synergistic effects of tanshinone IIA and andrographolide on the apoptosis of cancer cells via crosstalk between p53 and reactive oxygen species pathways. Pharmacological Reports 72:2, pages 400-417.
Crossref
Crossref
Dongdong Wang, Verena Hiebl, Tao Xu, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss & Verena M. Dirsch. (2020) Impact of natural products on the cholesterol transporter ABCA1. Journal of Ethnopharmacology 249, pages 112444.
Crossref
Crossref
Longkai Zhang, Weibin Lin, Xiaodan Chen, Gang Wei, Hailong Zhu & Shangping Xing. (2019) Tanshinone IIA reverses EGF‑ and TGF‑β1‑mediated epithelial‑mesenchymal transition in HepG2 cells via the PI3K/Akt/ERK signaling pathway. Oncology Letters.
Crossref
Crossref
Wenji Li, Davit Sargsyan, Renyi Wu, Shanyi Li, Lujing Wang, David Cheng & Ah-Ng Kong. (2019) DNA Methylome and Transcriptome Alterations in High Glucose-Induced Diabetic Nephropathy Cellular Model and Identification of Novel Targets for Treatment by Tanshinone IIA. Chemical Research in Toxicology 32:10, pages 1977-1988.
Crossref
Crossref
Bhawana Sharma, Aarti Yadav & Rajesh Dabur. (2019) Interactions of a medicinal climber Tinospora cordifolia with supportive interspecific plants trigger the modulation in its secondary metabolic profiles. Scientific Reports 9:1.
Crossref
Crossref
Dongdong Wang, Yang Yang, Yingnan Lei, Nikolay T. Tzvetkov, Xingde Liu, Andy Wai Kan Yeung, Suowen Xu & Atanas G. Atanasov. (2019) Targeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural Products. Pharmacological Reviews 71:4, pages 596-670.
Crossref
Crossref
Yukihiro Tambe, Tokio Terado, Chul Jang Kim, Ken‐ichi Mukaisho, Saori Yoshida, Hiroyuki Sugihara, Hiroyuki Tanaka, Junji Chida, Hiroshi Kido, Kenzaburo Yamaji, Tsuyoshi Yamamoto, Hirofumi Nakano, Satoshi Omura & Hirokazu Inoue. (2019) Antitumor activity of potent pyruvate dehydrogenase kinase 4 inhibitors from plants in pancreatic cancer. Molecular Carcinogenesis 58:10, pages 1726-1737.
Crossref
Crossref
Shuai Zhu, Ye-Hui Chen, Yong-Bin Wang, Peiyuan Yu, Shao-Yu Li, Shao-Hua Xiang, Jun-Qi Wang, Jian Xiao & Bin Tan. (2019) Organocatalytic atroposelective construction of axially chiral arylquinones. Nature Communications 10:1.
Crossref
Crossref
Lindsay K. Caesar, Sabina Nogo, Cassandra N. Naphen & Nadja B. Cech. (2019) Simplify: A Mass Spectrometry Metabolomics Approach to Identify Additives and Synergists from Complex Mixtures. Analytical Chemistry 91:17, pages 11297-11305.
Crossref
Crossref
Kunming Tian, Sayoko Ogura, Peter J. Little, Suo‐wen Xu & Tatsuya Sawamura. (2018) Targeting LOX‐1 in atherosclerosis and vasculopathy: current knowledge and future perspectives. Annals of the New York Academy of Sciences 1443:1, pages 34-53.
Crossref
Crossref
Chunyong Ding, Hongjin Chen, Bin Liang, Mingkun Jiao, Guang Liang & Ao Zhang. (2019) Biomimetic synthesis of the natural product salviadione and its hybrids: discovery of tissue-specific anti-inflammatory agents for acute lung injury. Chemical Science 10:17, pages 4667-4672.
Crossref
Crossref
Min Gao, Hao Ou, Yu Jiang, Kangkai Wang, Yue Peng, Huali Zhang, Mingshi Yang & Xianzhong Xiao. (2019) Tanshinone IIA attenuates sepsis-induced immunosuppression and improves survival rate in a mice peritonitis model. Biomedicine & Pharmacotherapy 112, pages 108609.
Crossref
Crossref
Xiaojun Feng, Yi Li, Yanan Wang, Lingli Li, Peter J. Little, Suo-wen Xu & Sheng Liu. (2019) Danhong injection in cardiovascular and cerebrovascular diseases: Pharmacological actions, molecular mechanisms, and therapeutic potential. Pharmacological Research 139, pages 62-75.
Crossref
Crossref
Xue-Mei Zhang, Jiao Ma, Yang Sun, Bing-Qian Yu, Zhuo-Min Jiao, Duo Wang, Mei-Yu Yu, Jin-Yue Li & Jin Fu. (2018) Tanshinone IIA promotes the differentiation of bone marrow mesenchymal stem cells into neuronal-like cells in a spinal cord injury model. Journal of Translational Medicine 16:1.
Crossref
Crossref
Choongho Lee. (2018) Therapeutic Modulation of Virus-Induced Oxidative Stress via the Nrf2-Dependent Antioxidative Pathway. Oxidative Medicine and Cellular Longevity 2018, pages 1-26.
Crossref
Crossref
Nan Li, Liang Yang, Baolian Zhang & Suqin Chen. (2018) Tanshinone IIA effects on ovarian cancer cell line. Journal of Pharmacy and Pharmacology 70:10, pages 1369-1377.
Crossref
Crossref
Hui Xu, Yu-li Hao, Li-na Xu, Liang Chen & Feng-wei Xu. (2018) Tanshinone sensitized the antitumor effects of irradiation on laryngeal cancer via JNK pathway. Cancer Medicine 7:10, pages 5187-5193.
Crossref
Crossref
Haitao Wang, Xiaoying Su, Jiankang Fang, Xingan Xin, Xia Zhao, Uma Gaur, Qiang Wen, Jiangping Xu, Peter Little & Wenhua Zheng. (2018) Tanshinone IIA Attenuates Insulin Like Growth Factor 1 -Induced Cell Proliferation in PC12 Cells through the PI3K/Akt and MEK/ERK Pathways. International Journal of Molecular Sciences 19:9, pages 2719.
Crossref
Crossref
Xiaxia Wu, Hongwei Gao, Ying Hou, Jie Yu, Wen Sun, Ying Wang, Xiaoyan Chen, Yulin Feng, Qiong-ming Xu & Xiuping Chen. (2018) Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways. Toxicology and Applied Pharmacology 355, pages 1-8.
Crossref
Crossref
Zhaohui Guo, Miao Yan, Lei Chen, Pingfei Fang, Zhihua Li, Zimeng Wan, Sisi Cao, Zhenyan Hou, Shanshan Wei, Wenqun Li & Bikui Zhang. (2018) Nrf2‑dependent antioxidant response mediated the protective effect of tanshinone IIA on doxorubicin‑induced cardiotoxicity. Experimental and Therapeutic Medicine.
Crossref
Crossref
Xian Li, Soon Jin Park, Fansi Jin, Yifeng Deng, Ju Hye Yang, Jae-Hoon Chang, Dong-Young Kim, Jung-Ae Kim, Youn Ju Lee, Makoto Murakami, Kun Ho Son & Hyeun Wook Chang. (2018) Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway. Biochemical Pharmacology 152, pages 362-372.
Crossref
Crossref
Zhuo-ming Li, Suo-wen Xu & Pei-qing Liu. (2018) Salvia miltiorrhizaBurge (Danshen): a golden herbal medicine in cardiovascular therapeutics. Acta Pharmacologica Sinica 39:5, pages 802-824.
Crossref
Crossref
Jian Fang, Peter J. Little & Suowen Xu. (2018) Atheroprotective Effects and Molecular Targets of Tanshinones Derived From Herbal Medicine Danshen. Medicinal Research Reviews 38:1, pages 201-228.
Crossref
Crossref
Liuting Zeng, Kailin Yang & Jinwen Ge. (2017) Uncovering the Pharmacological Mechanism of Astragalus Salvia Compound on Pregnancy-Induced Hypertension Syndrome by a Network Pharmacology Approach. Scientific Reports 7:1.
Crossref
Crossref
Tao Song, Yuan Yao, Teng Wang, He Huang & Hao Xia. (2017) Tanshinone IIA ameliorates apoptosis of myocardiocytes by up-regulation of miR-133 and suppression of Caspase-9. European Journal of Pharmacology 815, pages 343-350.
Crossref
Crossref
Azhar U. Khan, Nazia Malik & Tanvir Arfin. 2017. Nanocellulose and Nanohydrogel Matrices. Nanocellulose and Nanohydrogel Matrices
331
352
.
Min Zhao, Yaling Feng, Jianping Xiao, Jie Liang, Yongxiang Yin & Daozhen Chen. (2017) Sodium tanshinone IIA sulfonate prevents hypoxic trophoblast-induced endothelial cell dysfunction via targeting HMGB1 release. Journal of Biochemical and Molecular Toxicology 31:7, pages e21903.
Crossref
Crossref
Bing Liang, Shujuan Yu, Jie Li, Fan Wang, Gaolin Liang, Ao Zhang & Chunyong Ding. (2017) Site-selective Csp 3 -H aryloxylation of natural product Tanshinone IIA and its analogues. Tetrahedron Letters 58:19, pages 1822-1825.
Crossref
Crossref
Tao Wang, Chengxi Wang, Qiong Wu, Kangdi Zheng, Jiaojiao Chen, Yutao Lan, Yao Qin, Wenjie Mei & Baoguo Wang. (2017) Evaluation of Tanshinone IIA Developmental Toxicity in Zebrafish Embryos. Molecules 22:4, pages 660.
Crossref
Crossref
Cheng Qian, Yun Ren & Yongsheng Xia. (2017) Sodium tanshinone IIA sulfonate attenuates hemorrhagic shock-induced organ damages by nuclear factor-kappa B pathway. Journal of Surgical Research 209, pages 145-152.
Crossref
Crossref
Yan Li, Jinghui Wang, Feng Lin, Yinfeng Yang & Su-Shing Chen. (2017) A Methodology for Cancer Therapeutics by Systems Pharmacology-Based Analysis: A Case Study on Breast Cancer-Related Traditional Chinese Medicines. PLOS ONE 12:1, pages e0169363.
Crossref
Crossref
Yong-dong Yang, Xing Yu, Xiu-mei Wang, Xiao-hong Mu & Feng He. (2017) Tanshinone IIA improves functional recovery in spinal cord injury-induced lower urinary tract dysfunction. Neural Regeneration Research 12:2, pages 267.
Crossref
Crossref
Jun Xie, Jia-Hui Liu, Heng Liu, Xiao-Zhong Liao, Yuling Chen, Mei-Gui Lin, Yue-Yu Gu, Tao-Li Liu, Dong-Mei Wang, Hui Ge & Sui-Lin Mo. (2016) Tanshinone IIA combined with adriamycin inhibited malignant biological behaviors of NSCLC A549 cell line in a synergistic way. BMC Cancer 16:1.
Crossref
Crossref
Jun Feng, Shusheng Li & Huawen Chen. (2016) Tanshinone IIA ameliorates apoptosis of cardiomyocytes induced by endoplasmic reticulum stress. Experimental Biology and Medicine 241:18, pages 2042-2048.
Crossref
Crossref
Chunming Jiang, Wei Zhu, Xiang Yan, Qiuyuan Shao, Biao Xu, Miao Zhang & Rujun Gong. (2016) Rescue therapy with Tanshinone IIA hinders transition of acute kidney injury to chronic kidney disease via targeting GSK3β. Scientific Reports 6:1.
Crossref
Crossref
Wenwen Zhao, Chunxia Li, Hongwei Gao, Qin Wu, Jingshan Shi & Xiuping Chen. (2016) Dihydrotanshinone I Attenuates Atherosclerosis in ApoE-Deficient Mice: Role of NOX4/NF-κB Mediated Lectin-Like Oxidized LDL Receptor-1 (LOX-1) of the Endothelium. Frontiers in Pharmacology 7.
Crossref
Crossref
Chunyong Ding, Jie Li, Mingkun Jiao & Ao Zhang. (2016)
Catalyst-Free sp
3
C–H Acyloxylation: Regioselective Synthesis of 1-Acyloxy Derivatives of the Natural Product Tanshinone IIA
. Journal of Natural Products 79:10, pages 2514-2520.
Crossref
Crossref
Qian JiangWenju LuKai YangCyrus Hadadi, Xin FuYuqin ChenXin YunJie ZhangMeichan LiLei Xu, Haiyang TangJason X-J YuanJian WangDejun Sun. (2016) Sodium tanshinone IIA sulfonate inhibits hypoxia-induced enhancement of SOCE in pulmonary arterial smooth muscle cells via the PKG-PPAR-γ signaling axis. American Journal of Physiology-Cell Physiology 311:1, pages C136-C149.
Crossref
Crossref
Jun Yan, Xue Yang, Dong Han & Juan Feng. (2016) Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats. Molecular Medicine Reports.
Crossref
Crossref
MING SHU, XIAO-RONG HU, ZUO-AN HUNG, DAM-DAN HUANG & SHUN ZHANG. (2016) Effects of tanshinone IIA on fibrosis in a rat model of cirrhosis through heme oxygenase-1, inflammation, oxidative stress and apoptosis. Molecular Medicine Reports 13:4, pages 3036-3042.
Crossref
Crossref
Hyou-Ju Jin & Chun-Guang Li. (2016) Molecular Mechanisms of Cardioprotective Actions of Tanshinones. Journal of Chemistry 2016, pages 1-14.
Crossref
Crossref
Lunjie Lu, Jun Zhou, Jingying Zhang, Jun Che, Yang Jiao & Yusong Zhang. (2016) Prevention and Therapeutic Effects and Mechanisms of Tanshinone IIA Sodium Sulfonate on Acute Liver Injury Mice Model. Evidence-Based Complementary and Alternative Medicine 2016, pages 1-8.
Crossref
Crossref
Xue Yang, Jun Yan & Juan Feng. (2016) Treatment with tanshinone IIA suppresses disruption of the blood-brain barrier and reduces expression of adhesion molecules and chemokines in experimental autoimmune encephalomyelitis. European Journal of Pharmacology 771, pages 18-28.
Crossref
Crossref
Feng Feng, Ying Feng, Zhen Liu, Wei-Hua Li, Wen-Cong Wang, Zhong-Dao Wu & Zhiyue Lv. (2015) Effects of albendazole combined with TSII-A (a Chinese herb compound) on optic neuritis caused by Angiostrongylus cantonensis in BALB/c mice. Parasites & Vectors 8:1.
Crossref
Crossref
Zhiping Liu, Suowen Xu, Xiaoyang Huang, Jiaojiao Wang, Si Gao, Hong Li, Changhua Zhou, Jiantao Ye, Shaorui Chen, Zheng-Gen Jin & Peiqing Liu. (2015) Cryptotanshinone, an orally bioactive herbal compound from Danshen, attenuates atherosclerosis in apolipoprotein E-deficient mice: role of lectin-like oxidized LDL receptor-1 (LOX-1). British Journal of Pharmacology 172:23, pages 5661-5675.
Crossref
Crossref
Lei Wan, Yang Zou, Li-Hui Wan, Li-Qun Wang, Mei-Zhen Huang, Juan Wu, Yi-Bao Zhu & Ou-Ping Huang. (2015) Tanshinone IIA inhibits the proliferation, migration and invasion of ectopic endometrial stromal cells of adenomyosis via 14-3-3ζ downregulation. Archives of Gynecology and Obstetrics 292:6, pages 1301-1309.
Crossref
Crossref
Fenglai Xiao, Bo Yan, Lei Chen & Dong Zhou. (2015) Review of the use of botanicals for epilepsy in complementary medical systems — Traditional Chinese Medicine. Epilepsy & Behavior 52, pages 281-289.
Crossref
Crossref
Kejun Qian, Huazhong Xu, Teng Dai & Keqing Shi. (2015) Effects of Tanshinone IIA on osteogenic differentiation of mouse bone marrow mesenchymal stem cells. Naunyn-Schmiedeberg's Archives of Pharmacology 388:11, pages 1201-1209.
Crossref
Crossref
Shao-Jun CHEN. (2015) Drug-target networks for Tanshinone IIA identified by data mining. Chinese Journal of Natural Medicines 13:10, pages 751-759.
Crossref
Crossref
Dongdong Wang, Wuxia Zhang, Tingting Wang, Na Li, Haibo Mu, Jiwen Zhang & Jinyou Duan. (2015) Unveiling the Mode of Action of Two Antibacterial Tanshinone Derivatives. International Journal of Molecular Sciences 16:8, pages 17668-17681.
Crossref
Crossref
LE YANG, JIN HU, HONG-ZHEN HAO, ZHAO YIN, GANG LIU & XIAO-JING ZOU. (2015) Sodium tanshinone IIA sulfonate attenuates the transforming growth factor-β1-induced differentiation of atrial fibroblasts into myofibroblasts in vitro. International Journal of Molecular Medicine 35:4, pages 1026-1032.
Crossref
Crossref
Bingwen Lu & Xingwei Wu. (2015) Clinical Study of Sulfotanshinone Sodium Injection in Treating Non-Ischemic Retinal Vein Occlusion. Chinese Medicine 06:02, pages 83-89.
Crossref
Crossref
Zihan Xu, Lijun Wu, Yaowen Sun, Yadong Guo, Gaoping Qin, Shengzhi Mu, Ronghui Fan, Benfeng Wang, Wenjie Gao & Zhenxin Zhang. (2014) Tanshinone IIA pretreatment protects free flaps against hypoxic injury by upregulating stem cell-related biomarkers in epithelial skin cells. BMC Complementary and Alternative Medicine 14:1.
Crossref
Crossref
Jinming Zhang, Yingbo Li, Xiefan Fang, Demin Zhou, Yitao Wang & Meiwan Chen. (2014) TPGS-g-PLGA/Pluronic F68 mixed micelles for tanshinone IIA delivery in cancer therapy. International Journal of Pharmaceutics 476:1-2, pages 185-198.
Crossref
Crossref
Zihan Xu, Zhenxin Zhang, Lijun Wu, Yaowen Sun, Yadong Guo, Gaoping Qin, Shengzhi Mu, Ronghui Fan, Benfeng Wang & Wenjie Gao. (2014) Tanshinone IIA Pretreatment Renders Free Flaps against Hypoxic Injury through Activating Wnt Signaling and Upregulating Stem Cell-Related Biomarkers. International Journal of Molecular Sciences 15:10, pages 18117-18130.
Crossref
Crossref
Francesco Maione, Vincenzo De Feo, Elisabetta Caiazzo, Laura De Martino, Carla Cicala & Nicola Mascolo. (2014) Tanshinone IIA, a major component of Salvia milthorriza Bunge, inhibits platelet activation via Erk-2 signaling pathway. Journal of Ethnopharmacology 155:2, pages 1236-1242.
Crossref
Crossref
Hong-Sheng Zhang, Xin-Yu Chen, Tong-Chao Wu & Feng-Juan Zhang. (2014) Tanshinone II A Inhibits Tat-Induced HIV-1 Transactivation Through Redox-Regulated AMPK/Nampt Pathway. Journal of Cellular Physiology 229:9, pages 1193-1201.
Crossref
Crossref
Qingxiong Yu, Lingling Sheng, Mei Yang, Ming Zhu, Xiaolu Huang & Qingfeng Li. (2014) Tanshinon IIA Injection Accelerates Tissue Expansion by Reducing the Formation of the Fibrous Capsule. PLoS ONE 9:8, pages e105756.
Crossref
Crossref
JIAN ZHANG, JU WANG, JIU-YANG JIANG, SHANG-DIAN LIU, KAI FU & HONG-YU LIU. (2014) Tanshinone IIA induces cytochrome c-mediated caspase cascade apoptosis in A549 human lung cancer cells via the JNK pathway. International Journal of Oncology 45:2, pages 683-690.
Crossref
Crossref
Suowen Xu, Zhiping Liu, Yan Huang, Jianwen Chen, Shaorui Chen, Xiaoyan Shen, Heqing Huang & Peiqing Liu. (2014) Effectiveness of combination therapy of atorvastatin and non lipid-modifying tanshinone IIA from Danshen in a mouse model of atherosclerosis. International Journal of Cardiology 174:3, pages 878-880.
Crossref
Crossref
Shao-Jun Chen. (2014) A Potential Target of Tanshinone IIA for Acute Promyelocytic Leukemia Revealed by Inverse Docking and Drug Repurposing. Asian Pacific Journal of Cancer Prevention 15:10, pages 4301-4305.
Crossref
Crossref
Hui Pang, Bing Han, Tao Yu & Zhen Peng. (2014) The Complex Regulation of Tanshinone IIA in Rats with Hypertension-Induced Left Ventricular Hypertrophy. PLoS ONE 9:3, pages e92216.
Crossref
Crossref
Zhiping Liu, Jiaojiao Wang, Erwen Huang, Si Gao, Hong Li, Jing Lu, Kunming Tian, Peter J. Little, Xiaoyan Shen, Suowen Xu & Peiqing Liu. (2014) Tanshinone IIA suppresses cholesterol accumulation in human macrophages: role of heme oxygenase-1. Journal of Lipid Research 55:2, pages 201-213.
Crossref
Crossref
Yan Wang, Frankie Costanza, Haifan Wu, Daqian Song, Jianfeng Cai & Qi Li. (2014) PEG–poly(amino acid)s-encapsulated tanshinone IIA as potential therapeutics for the treatment of hepatoma. J. Mater. Chem. B 2:20, pages 3115-3122.
Crossref
Crossref
Olivia Erin Buenafe, Adriana Orellana-Paucar, Jan Maes, Hao Huang, Xuhui Ying, Wim De Borggraeve, Alexander D. Crawford, Walter Luyten, Camila V. Esguerra & Peter de Witte. (2013) Tanshinone IIA Exhibits Anticonvulsant Activity in Zebrafish and Mouse Seizure Models. ACS Chemical Neuroscience 4:11, pages 1479-1487.
Crossref
Crossref
Xiang-Shan Tan, Jing-Yi Ma, Ru Feng, Chao Ma, Wen-Jing Chen, Yu-Peng Sun, Jie Fu, Min Huang, Chi-Yu He, Jia-Wen Shou, Wen-Yi He, Yan Wang & Jian-Dong Jiang. (2013) Tissue Distribution of Berberine and Its Metabolites after Oral Administration in Rats. PLoS ONE 8:10, pages e77969.
Crossref
Crossref
Ji Hoon Jung, Tae-Rin Kwon, Soo-Jin Jeong, Eun-Ok Kim, Eun Jung Sohn, Miyong Yun & Sung-Hoon Kim. (2013) Apoptosis Induced by Tanshinone IIA and Cryptotanshinone Is Mediated by Distinct JAK/STAT3/5 and SHP1/2 Signaling in Chronic Myeloid Leukemia K562 Cells. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-10.
Crossref
Crossref