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Expert Opinion on Therapeutic Patents Volume 25, 2015 - Issue 12
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Therapeutic application of vitamin D receptor ligands: an updated patent review

Ichiro TakadaNihon University School of Medicine, Division of Biochemistry, Department of Biomedical Sciences, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan+81 3 39 72 81 99; +81 3 39 72 81 99; [email protected]
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Makoto MakishimaNihon University School of Medicine, Division of Biochemistry, Department of Biomedical Sciences, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan+81 3 39 72 81 99; +81 3 39 72 81 99; [email protected]
Pages 1373-1383 | Published online: 24 Sep 2015

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Miguel A. Maestro, Ferdinand Molnár, Antonio Mouriño & Carsten Carlberg. (2016) Vitamin D receptor 2016: novel ligands and structural insights. Expert Opinion on Therapeutic Patents 26:11, pages 1291-1306.
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Articles from other publishers (13)

Meifang Zheng, Hongyan Li, Yanhang Gao, David R. Brigstock & Runping Gao. (2023) Vitamin D3 analogue calcipotriol inhibits the profibrotic effects of transforming growth factor- β1 on pancreatic stellate cells. European Journal of Pharmacology 957, pages 176000.
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Sayuri Takahashi, Ichiro Takada, Kenichi Hashimoto, Atsushi Yokoyama, Tohru Nakagawa, Makoto Makishima & Haruki Kume. (2023) ESS2 controls prostate cancer progression through recruitment of chromodomain helicase DNA binding protein 1. Scientific Reports 13:1.
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Hitomi Kubota, Michiyasu Ishizawa, Makoto Kodama, Yoshihiro Nagase, Shigeaki Kato, Makoto Makishima & Kenichi Sakurai. (2023) Vitamin D Receptor Mediates Attenuating Effect of Lithocholic Acid on Dextran Sulfate Sodium Induced Colitis in Mice. International Journal of Molecular Sciences 24:4, pages 3517.
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Randy Przybylla, Christina Susanne Mullins, Mathias Krohn, Stefan Oswald & Michael Linnebacher. (2022) Establishment and Characterization of Novel Human Intestinal In Vitro Models for Absorption and First-Pass Metabolism Studies. International Journal of Molecular Sciences 23:17, pages 9861.
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Carmen M. González, Sunil Gaikwad, Gonzalo Lasanta, Julian Loureiro, Niclas Nilsson, Carole Peluso-Iltis, Natacha Rochel & Antonio Mouriño. (2021) Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR). Bioorganic Chemistry 115, pages 105202.
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Zisheng Kang, Cong Wang, Yu Tong, Yanyi Li, Yi Gao, Siyuan Hou, Meixi Hao, Xiaolin Han, Bin Wang, Qianqian Wang & Can Zhang. (2020) Novel Nonsecosteroidal Vitamin D Receptor Modulator Combined with Gemcitabine Enhances Pancreatic Cancer Therapy through Remodeling of the Tumor Microenvironment. Journal of Medicinal Chemistry 64:1, pages 629-643.
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Daniela Caccamo, Sergio Ricca, Monica Currò & Riccardo Ientile. (2018) Health Risks of Hypovitaminosis D: A Review of New Molecular Insights. International Journal of Molecular Sciences 19:3, pages 892.
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Stefan Tukaj, Katja Bieber, Mareike Witte, Saeedeh Ghorbanalipoor, Enno Schmidt, Detlef Zillikens, Ralf J. Ludwig & Michael Kasperkiewicz. (2018) Calcitriol Treatment Ameliorates Inflammation and Blistering in Mouse Models of Epidermolysis Bullosa Acquisita. Journal of Investigative Dermatology 138:2, pages 301-309.
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Makoto Makishima & Sachiko Yamada. 2018. Vitamin D. Vitamin D 629 646 .
Kelly A. Teske, Ganesha Rai, Premchendar Nandhikonda, Preetpal S. Sidhu, Belaynesh Feleke, Anton Simeonov, Adam Yasgar, Ajit Jadhav, David J. Maloney & Leggy A. Arnold. (2017) Parallel Chemistry Approach to Identify Novel Nuclear Receptor Ligands Based on the GW0742 Scaffold. ACS Combinatorial Science 19:10, pages 646-656.
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Michiyasu Ishizawa, Daisuke Akagi, Jumpei Yamamoto & Makoto Makishima. (2017) 1α,25-Dihydroxyvitamin D3 enhances TRPV6 transcription through p38 MAPK activation and GADD45 expression. The Journal of Steroid Biochemistry and Molecular Biology 172, pages 55-61.
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Makoto Makishima. 2017. Bile Acids in Gastroenterology. Bile Acids in Gastroenterology 43 59 .
Lisa Asano, Tsuyoshi Waku, Rumi Abe, Naoyuki Kuwabara, Ichiaki Ito, Junn Yanagisawa, Kazuo Nagasawa & Toshiyuki Shimizu. (2016) Regulation of the vitamin D receptor by vitamin D lactam derivatives. FEBS Letters 590:18, pages 3270-3279.
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